Clinical trials: Degenerative Joint Disease
Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis
Tornier Perform™ Reversed Monopost Study
This study is a Multi-center, Prospective Follow-up, Non-significant risk, Post-Market Clinical Follow-Up (PMCF) study to Evaluate the Safety and Effectiveness of the Tornier Perform™ Reversed MonoPost System.
- Conditions
- Non-inflammatory Degenerative Joint Disease, Rhematoid Arthritis, Correction of Functional Deformity, Fracture of the Humeral Head
- Trial name
- Monarch (NCT07764614)
- Testing
- Tornier Perform™ Reversed MonoPost
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Stryker Trauma and Extremities
Osteoarthritis, Knee Pain Arthritis
Long-Term Study of CartiPRO for Knee Pain Due to Osteoarthritis or Cartilage Damage
This clinical trial aims to evaluate and compare the efficacy and safety of CartiPRO, an approved intra-articular atelocollagen injection, versus Synovian injection for the relief of knee pain in patients with knee…
- Conditions
- Osteoarthritis, Knee Pain Arthritis, Cartilage Defects of the Knee, Knee Osteoarthritis
- Trial name
- NCT07267793
- Testing
- CartiPRO, Synovian®
- Where
- 5 sites in South Korea
- Volunteers
- 194 people
- Sponsor
- DALIM TISSEN Co., Ltd.
Noninflammatory Degenerative Joint Disease
Survivorship of Attune Primary Total Knee Prosthesis
This post-marketing investigation will evaluate the long term (up to 15 years) survivorship of the Attune Primary Knee Prosthesis in patients with non-inflammatory degenerative joint disease.
- Trial name
- NCT01754363
- Testing
- Attune Primary Total Knee Replacement
- Where
- 27 sites in United States, Australia and 10 more
- Volunteers
- 1,542 people
- Sponsor
- DePuy International
Degenerative Joint Disease
Journey II BCS EU Observational Trial
Post-market study to confirm the safety and efficacy of the Journey II BCS knee prosthesis.
- Trial name
- NCT02211794
- Testing
- data collection
- Where
- 5 sites in Belgium, Italy and 3 more
- Volunteers
- 179 people
- Sponsor
- Smith & Nephew Orthopaedics AG
Degenerative Joint Disease, Osteoarthritis, Hip
Safety and Effectiveness of the HIT Reverse HRS
The purpose of this study is to determine if the use of the HIT Reverse Hip Replacement System is safe and effective in patients undergoing total hip replacement.
- Conditions
- Degenerative Joint Disease, Osteoarthritis, Hip, Avascular Necrosis of Hip, Traumatic Arthropathy-Hip
- Trial name
- NCT05357378
- Testing
- Hip Innovation Technology Reverse Hip Replacement System, Already-marketed semi-constrained uncemented hip systems using a metal-on-XLPE or ceramic-on-XLPE bearing combination.
- Where
- 6 sites in United States
- Volunteers
- 288 people
- Sponsor
- Hip Innovation Technology
Disc Degenerative Disease, Spine Degeneration
Physiotherapy and Osteopathic Treatment for Pain in the Cervical and Lumbar Spine and Temporomandibular Joints
Study Summary: Effectiveness of Physiotherapy and Osteopathy in Treating Spinal and Temporomandibular Joint Pain About the Study and Its Objective This study is conducted by Artur Hołodniuk, MSc, a physiotherapist and academic…
- Conditions
- Disc Degenerative Disease, Spine Degeneration, Back Ache, Temporomandibular Disorder (TMD)
- Trial name
- NCT07830836
- Testing
- General Osteopathic Treatment, Visceral Therapy, Magnetic field therapy
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Knee Osteoarthritis, Osteoarthritis (OA)
Clinical Outcomes of Intraarticular Platelet-Rich Plasma Injection in Knee Osteoarthritis
This prospective single-arm interventional study was designed to assess the short-term clinical outcomes of intra-articular platelet-rich plasma (PRP) injections in patients with Kellgren-Lawrence grade II and III knee…
- Conditions
- Knee Osteoarthritis, Osteoarthritis (OA), Degenerative Joint Disease of Knee, Knee Pain
- Trial name
- NCT07828561
- Testing
- Platelet-Rich Plasma (PRP)
- Where
- Nepal
- Volunteers
- 59 people
- Sponsor
- KIST Medical and Teaching Hospital
Degenerative Osteoarthritis
A Study to Determine the Safety and Efficacy of TG-C in Subjects With Kellgren and Lawrence Grade 2 or 3 OA of the Knee
A randomized, double-blind, placebo-controlled, multi-center, phase 3 study to determine the safety and efficacy of TG-C in subjects with Kellgren and Lawrence Grade 2 or 3 Osteoarthritis of the Knee, Osteoarthritis Research…
- Trial name
- NCT03203330
- Testing
- TG-C
- Where
- 44 sites in United States
- Volunteers
- 535 people
- Sponsor
- Kolon TissueGene, Inc.
Degenerative Osteoarthritis
Study to Determine the Efficacy and Safety of TG-C in Subjects With Kellgren/Lawrence Grade 2 or 3 OA of the Knee
A randomized, double-blind, placebo-controlled, multi-center, phase 3 study to determine the efficacy and safety of TG-C in subjects with Kellgren and Lawrence Grade 2 or 3 Osteoarthritis of the Knee, Osteoarthritis Research…
- Trial name
- NCT03291470
- Testing
- TG-C
- Where
- 27 sites in United States
- Volunteers
- 531 people
- Sponsor
- Kolon TissueGene, Inc.
Degenerative Osteoarthritis
A Study to Determine the Safety and Efficacy of TG-C in Subjects With Symptomatic Early Hip Osteoarthritis
A Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study to Determine the Efficacy, Safety, and Dosing of TG-C in Adult Subjects with Symptomatic Early Hip Osteoarthritis.
- Trial name
- NCT05276011
- Testing
- TG-C
- Volunteers
- 255 people
- Sponsor
- Kolon TissueGene, Inc.
Shoulder Impingement, Shoulder Pain
Study of the Effect of Neck Treatment on Shoulder Impingement
The purpose of this pilot study is to conduct research to determine the most effective physical therapy treatment for a condition called shoulder impingement.
- Conditions
- Shoulder Impingement, Shoulder Pain, Rotator Cuff Tendinitis, Cervical Degenerative Joint Disease
- Trial name
- NCT00764764
- Testing
- shoulder treatment, Shoulder AND cervical treatment
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- CAMC Health System
Osteoarthritis; Primary, Degenerative Joint Disease of Knee
A Multidisciplinary Intervention in Total Knee Arthroplasty
The purpose of this study is to investigate the effectiveness of cognitive behavioral therapy delivered as an e-therapy program, combined with physical exercise delivered by physiotherapists, for patients on waiting list for…
- Trial name
- MultiKnee (NCT03771430)
- Testing
- Osteoarthritis education, exercise and CBT, Total Knee Arthroplasty
- Where
- 3 sites in Norway
- Volunteers
- 282 people
- Sponsor
- Lovisenberg Diakonale Hospital
Inflammatory Arthritis, Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis)
A Multi-Center Study Assessing the Safety and Efficacy of the LEGION Medial Stabilized (MS) Insert in Patients Undergoing a Total Knee Arthroplasty (TKA)
The purpose of this study is to assess the long-term safety and performance of the LEGION Medial Stabilized insert and to generate clinical evidence to support and maintain product registration in global markets.
- Conditions
- Inflammatory Arthritis, Primary Total Knee Arthroplasty Due to Degenerative Joint Disease (Primary Diagnosis of Osteoarthritis), Post-traumatic Arthritis
- Trial name
- NCT07199738
- Testing
- Cemented CoCr, Cemented Oxinium, Cementless
- Where
- 4 sites in United States
- Volunteers
- 144 people
- Sponsor
- Smith & Nephew, Inc.
Total Hip Arthroplasty, Degenerative Joint Disease of Hip
G7 Acetabular System With Vivacit-E or Longevity Liner PMCF Study
The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of the G7 Acetabular Shells when used with the Vivacit-E and Longevity HXLPE liners and instrumentation in primary and…
- Conditions
- Total Hip Arthroplasty, Degenerative Joint Disease of Hip, Avascular Necrosis of Hip, Rheumatoid Arthritis of Hip
- Trial name
- NCT04754087
- Testing
- Vivacit-E and Longevity (HXLPE) Liners
- Where
- 11 sites in United States, Denmark and 3 more
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Zimmer Biomet
Elbow Joint Destruction, Post-traumatic Lesions
Clinical Outcomes Study of the Nexel Total Elbow
The objectives of the study are to confirm safety and performance of the Zimmer Nexel Total Elbow when used in primary or revision total elbow replacement.
- Conditions
- Elbow Joint Destruction, Post-traumatic Lesions, Ankylosed Joints, Advanced Rheumatoid Arthritis
- Trial name
- NCT02469662
- Testing
- Nexel Total Elbow
- Where
- 11 sites in United States, Australia and 6 more
- Volunteers
- 134 people
- Sponsor
- Zimmer Biomet
Degenerative Joint Disease of Knee, Rheumatoid Arthritis
Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.
Degenerative knee joint diseases are characterized by chronic pain, inflammation, and functional impairment. In these conditions, mast cell density in the synovial membrane is increased, resulting in an excessive release of…
- Trial name
- NCT07680101
- Testing
- Adelmidrol 2% / Hyaluronic Acid 1%, micronized Palmitoylethanolamide (mPEA) 300mg + ultramicronized Palmitoylethanolamide (umPEA) 600mg
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Universita di Verona
Degenerative Osteoarthritis, Degenerative Lumbar Vertebra
Efficacy and Safety Study of Lumbar Interbody Fusion With MatriTMBONE Associated With Autologous Bone Marrow
The main objective of this clinical study is the estimation of the rate of intersomatic fusion observed 12 months after lumbar interbody fusion by posterior approach with PEEK interbody cage of fusion in PEEK performed with…
- Trial name
- MatriBone (NCT01335243)
- Testing
- The Transforaminal Lumbar Interbody Fusion (TLIF) surgery
- Where
- France
- Volunteers
- 32 people
- Sponsor
- University Hospital, Bordeaux
Degenerative Joint Disease, Control Subjects
MRI of the TMJ in Patients With DJD
This observational research is comparative in design, that is assessing the change in qMRI measures in degenerative changes of the TMJ in patients diagnosed with DJD.
- Trial name
- NCT07008690
- Testing
- MRI, Magnetic Resonance Imaging
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis
Sidus(TM) Post Market Clinical Follow-up (PMCF) Study
This post market clinical follow-up study is designed to confirm safety and performance of the Sidus Stem-Free Shoulder when used in hemi or total shoulder arthroplasty.
- Conditions
- Non-inflammatory Degenerative Joint Disease (NIDJD), Avascular Necrosis, Osteoarthritis, Inflammatory Joint Disease (IJD)
- Trial name
- NCT01700543
- Testing
- Shoulder Arthroplasty
- Where
- 8 sites in Austria, France and 3 more
- Volunteers
- 152 people
- Sponsor
- Zimmer Biomet
Shoulder Fractures, Shoulder Arthritis Osteoarthritis
Zimmer Biomet Shoulder Arthroplasty PMCF Study
This is a multicenter, prospective, non-controlled post market surveillance study. The objectives of this study are to confirm the safety, performance, and clinical benefits of the Zimmer Biomet Shoulder Arthroplasty systems in…
- Conditions
- Shoulder Fractures, Shoulder Arthritis Osteoarthritis, Shoulder Injury, Shoulder Pain
- Trial name
- NCT06920459
- Testing
- Alliance™ Glenoid
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 50 people
- Sponsor
- Zimmer Biomet