Clinical trials: Deep Venous Thrombosis
Neoplasms, Deep Vein Thrombosis
Outpatient Treatment Of Deep Venous Thrombosis Using Subcutaneous Dalteparin (Fragmin) In Low Risk Cancer Patients
Study Plan: Adult cancer patients who have a low risk profile and present with DVT will receive dalteparin 200 IU/kg subcutaneously daily (based on actual body weight with a maximum dose of 18,000 IU).
- Trial name
- NCT00041782
- Testing
- Dalteparin (Fragmin)
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Thrombolysis, Symptomatic Proximal Deep Vein Thrombosis
A Study to Learn More About How Well BAY3018250 Works and How Safe it is for People With Proximal Deep Vein Thrombosis
Researchers are looking for a better way to treat people who have deep vein thrombosis (DVT). DVT is a condition that occurs when a blood clot forms in a deep vein in the leg.
- Trial name
- SIRIUS (NCT06149520)
- Testing
- BAY3018250
- Where
- 68 sites in Belgium, Bulgaria and 11 more
- Volunteers
- 283 people
- Sponsor
- Bayer
Isolated Distal DVT, Proximal DVT
Natural History of Isolated Deep Vein Thrombosis of the Calf
Whether isolated distal DVT (IDDVT), DVT confined to the calf, should be looked for and diagnosed to allow them to be treated with anticoagulants remains one of the still unsolved issues in vascular medicine, especially because…
- Conditions
- Isolated Distal DVT, Proximal DVT, Pulmonary Embolism
- Trial name
- CALTHRO (NCT00816920)
- Testing
- Ultrasound examination of leg veins
- Where
- 2 sites in Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Deep Vein Thrombosis
Residual Vein Thrombosis Establishes the Optimal Duration of Oral Anticoagulants
ABSTRACT Background The optimal duration of oral anticoagulant treatment in patients with idiopathic venous thromboembolism is still uncertain .
- Trial name
- DACUS (NCT00438230)
- Testing
- Warfarin
- Volunteers
- 250 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico
Venous Thromboembolism, Deep Vein Thrombosis
Global Anticoagulant Registry in the FIELD- Venous Thromboembolic Events
The protocol is a large registry to describe acute, sub-acute and extended duration of anticoagulation management, clinical and economic duration of anticoagulation management, clinical and economic outcomes in patients with…
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- GARFIELD-VTE (NCT02155491)
- Where
- United States
- Volunteers
- 10,679 people
- Sponsor
- Thrombosis Research Institute
Deep Vein Thrombosis
Whole-leg Ultrasound in Pregnant Patients
This study seeks to determine the rate of thromboembolic complications (blood clots), including death attributed to thromboembolic disease, when anticoagulation (blood thinner) therapy is withheld from pregnant patients suspected…
- Trial name
- CLOT-3 (NCT01319474)
- Testing
- Whole-leg compression ultrasound
- Where
- United States
- Volunteers
- 268 people
- Sponsor
- Intermountain Health Care, Inc.
Deep Vein Thrombosis, Total Hip Prosthesis
Generation of Thrombin and Prediction of Deep Vein Thrombosis Post Prosthetic Orthopedic Surgery of the Lower Limbs
The numerical ratio between the value of the thrombin generation test performed without soluble thrombomodulin and the value of the thrombin generation test performed in the presence of soluble thrombomodulin, performed…
- Conditions
- Deep Vein Thrombosis, Total Hip Prosthesis, Knee Prosthesis
- Trial name
- GT-PT (NCT03634124)
- Testing
- Blood test, Doppler ultrasound
- Where
- France
- Volunteers
- 146 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Deep Vein Thrombosis
New Clinical Score for Deep Vein Thrombosis
A new Clinical Score (CS) to rule out Deep Vein Thrombosis (DVT) has to be derived and internally validated (with bootstrap method), from patients suspected of DVT in Italy.
- Trial name
- NCT05680636
- Testing
- temperature measurement
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Accademia Italiana Medicina Osteopatica
Thromboembolism, Arthroplasty Replacement, Knee
Safety Study of Stopping Thromboprophylaxis Based on Ultrasound Results After Total Knee Replacement
The purpose of this study is to determine whether stopping Low Molecular Weight Heparin (LMWH) thromboprophylaxis is safe after total knee joint replacement.
- Trial name
- NCT00362492
- Testing
- Bilateral ultrasound examination 7+/- 2 after surgery
- Where
- 17 sites in France
- Volunteers
- 850 people
- Sponsor
- University Hospital, Caen
Venous Thrombosis (Disorder)
Patient Education Bundle vs. Nurses Feedback and Coaching to Prevent Missed Doses of VTE Prophylaxis
VTE associated harm is underappreciated among hospitalized patients and may be associated with missed doses of VTE prophylaxis medications.
- Trial name
- ENACT (NCT03367364)
- Testing
- Patient education bundle (PEB),, Nurse feedback and coaching (NFC)
- Where
- United States
- Volunteers
- 9,657 people
- Sponsor
- Johns Hopkins University
Venous Thromboembolism
Multicenter Registry for Effectiveness Analysis of ActiveCare+S.F.T® Mobile Compression Device for Thrombosis Prevention in Hip and Knee Arthroplasty
Venous thromboembolic events (VTE), either deep vein thromboses or pulmonary emboli, are important complications in patients undergoing knee or hip arthroplasty.
- Trial name
- ACOR (NCT01984190)
- Where
- 10 sites in United States
- Volunteers
- 411 people
- Sponsor
- Medical Compression Systems
Deep Venous Thrombosis
Deep Venous Thrombosis in Non-severe COVID-19 Patients Hospitalized for a Neurovascular Pathology
Severe SARS-CoV-2 infection, responsible of COVID-19, is accompanied by many venous thromboembolic events. Antithrombotic treatment is the cornerstone of management of many neurovascular diseases (NVDs) and the benefit-risk ratio…
- Trial name
- VT-Covid-19 (NCT04452422)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Strasbourg, France
Atrial Fibrillation, Deep Vein Thrombosis
Pilot Study: Comparison of Patients' Knowledge of Direct Oral Anticoagulants in Post-hospitalization Between 2 Cardiology Departments Offering or Not a Pharmaceutical Interview During Hospitalization
Direct oral anticoagulants (Rivaroxaban, Apixaban and Dabigatran) are an alternative to anti-vitamin K drugs and low molecular weight heparins in many cardiovascular diseases.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- EDUC-AOD (NCT04674202)
- Testing
- Phone interview
- Where
- 2 sites in France
- Volunteers
- 154 people
- Sponsor
- Direction Centrale du Service de Santé des Armées
Venous Thrombosis
Ongoing Registry of Deep Venous Reconstructions
Ongoing registration of deep venous obstructive disease patients treated by means of percutaneous transluminal angioplasty (PTA) and stenting with or without endophlebectomy (surgical desobstruction, also termed endovenectomy) of…
- Trial name
- NCT02650453
- Testing
- Deep venous reconstruction
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Maastricht University Medical Center
Venous Thromboses, Venous Disease
The GORE® VIABAHN® FORTEGRA Venous Stent IVC Study
This study is a prospective, multicenter, non-randomized, single-arm study to evaluate the performance, safety, and efficacy of the GORE® VIABAHN® FORTEGRA Venous Stent (formerly known as GORE® VIAFORT Vascular Stent) for…
- Conditions
- Venous Thromboses, Venous Disease, Venous Leg Ulcer, Venous Stasis
- Trial name
- NCT05409976
- Testing
- GORE® VIAFORT Vascular Stent
- Where
- 17 sites in United States, Australia and 5 more
- Volunteers
- 136 people
- Sponsor
- W.L.Gore & Associates
Atrial Fibrillation, Deep Vein Thrombosis
Genotype-Guided Warfarin Therapy Trial
The purpose of the investigators' study is to determine the clinical utility of a warfarin-dosing algorithm that incorporates genetic information (VKORC1 and CYP2C9 alleles) for adult patients initiating warfarin therapy.
- Conditions
- Atrial Fibrillation, Deep Vein Thrombosis, Pulmonary Embolism, Artificial Heart Valve
- Trial name
- WARFPGX (NCT00904293)
- Testing
- Genotype-guided dose determination, Non-genotype guided warfarin dosing
- Where
- United States
- Volunteers
- 109 people
- Sponsor
- University of North Carolina, Chapel Hill
Tranexamic Acid, Trauma
Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery Tranexamic Acid in Trauma Surgery
This study was done to evaluate the efficacy of Tranexamic Acid (TXA) in reducing blood transfusion requirement in patients of lower limb trauma undergoing surgery.
- Conditions
- Tranexamic Acid, Trauma, Lower Extremity Fracture
- Trial name
- NCT04986813
- Testing
- Tranexamic acid injection, Normal Saline
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Jaspreet Singh
Venous Thromboembolism
Examining the Benefit of Graduated Compression Stockings in the Prevention of vEnous Thromboembolism in Low-risk Surgical Patients
Hospital acquired thrombosis describes blood clots that form in the legs and lungs after someone is treated in hospital. Clots in the leg can cause swelling, pain and other problems.
- Trial name
- PETS (NCT05347550)
- Testing
- Graduated Compression Stockings - Thromboembolic deterrent stockings
- Where
- 9 sites in United Kingdom
- Volunteers
- 21,472 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Venous Thromboembolism, Pulmonary Embolism
Venous Thromboembolism in DM1
The risk for venous thromboembolism (VTE) in DM1 and in other inherited myopathies, which can lead to chronic immobilization, are unknown.
- Conditions
- Venous Thromboembolism, Pulmonary Embolism, Deep Vein Thrombosis, Myopathy
- Trial name
- DM1-VTE (NCT03141749)
- Volunteers
- 2,810 people
- Sponsor
- Institut de Myologie, France
Acute Deep Venous Thrombosis of the Lower Extremity
Low-Dose Alteplase to Treat Blood Clots in Deep Leg Veins
This study will test the effectiveness of low-dose recombinant tissue plasminogen activator (rtPA, or alteplase) in dissolving blood clots in deep leg veins.
- Trial name
- NCT00082355
- Testing
- Alteplase (Activase, Genentech)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Richard Chang, M.D.