Clinical trials: Deep Endometriosis, open to volunteers
Endometriosis, Endometriosis (Diagnosis)
Deep Endometriosis Affecting the Urogenital Tract: Long-term Outcomes and Impact on Renal Function
Endometriosis is a chronic estrogen-dependent disease characterized by the presence and growth of endometrium-like tissue outside the uterine cavity.
- Conditions
- Endometriosis, Endometriosis (Diagnosis), Urinary Tract Diseases
- Trial name
- RENDO (NCT07776574)
- Where
- Czechia
- Volunteers
- 20 people
- Sponsor
- Charles University, Czech Republic
Endometriosis, Ovarian Reserve
Impact of Surgery for Deep Posterior Endometriosis on Ovarian Reserve (ENDORO)
Endometriosis is a chronic condition typically affecting women of reproductive age and often responsible for chronic pelvic pain and/or infertility. Its prevalence is estimated at 10% of the female population.
- Trial name
- ENDORO (NCT07469007)
- Testing
- pelvic ultrasound, Anti-Müllerian hormone assay, Questionnaire
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Deep Infiltrating Endometriosis (DIE), Transrectal Ultrasound
Evaluation of Rectal Infiltration Depth and Length in Bowel Involvement of Deep Infiltrative Endometriosis (DIE) Using Intraoperative Transrectal Ultrasound (TRUS)
we aim to evaluate the success of intraoperative transrectal ultrasound in measuring the depth and extent of bowel involvement in patients preoperatively diagnosed with intestinal endometriosis using transvaginal ultrasound and…
- Conditions
- Deep Infiltrating Endometriosis (DIE), Transrectal Ultrasound, Bowel Endometriosis, Bowel Resection
- Trial name
- DIE IO TRUS (NCT06776536)
- Testing
- Transrectal ultrasound of the bowel endometriosis during operation
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Deep Infiltrating Endometriosis
Quality of Life and Fertility of Patient With Deep Surgical Endometriosis: a Prospective Cohort
Endometriosis is a common gynaecologic disease affecting 5 to 15% women of reproductive age and up to 40% of infertile women. It is characterized by the presence of active endometrial tissue outside the uterine cavity…
- Trial name
- ENDORAA (NCT03555903)
- Testing
- Endometriosis cohort
- Where
- France
- Volunteers
- 500 people
- Sponsor
- Hospices Civils de Lyon
Endometriosis, Endometriosis-related Pain
Intraoperative Sono-assessment In Deep Endometriosis
Deep infiltrating endometriosis (DIE) involving the bowel, particularly the rectosigmoid region, is associated with significant gastrointestinal symptoms and impaired quality of life.
- Conditions
- Endometriosis, Endometriosis-related Pain, Pelvic Pain Syndrome, Endometriosis, Rectum
- Trial name
- INSIDE (NCT07517081)
- Volunteers
- 57 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Endometriosis, Deep Endometriosis
The Association Between Deep Endometriosis and the Occurrence of Colorectal Carcinoma
The goal of this study is to identify the molecular or genetic mechanisms that may predispose patients with bowel endometriosis to an increased risk of colorectal carcinoma.
- Conditions
- Endometriosis, Deep Endometriosis, Bowel Endometriosis, Colorectal Carcinoma
- Trial name
- NCT07386431
- Volunteers
- 30 people
- Sponsor
- University Medical Centre Ljubljana
Endometriosis (Diagnosis), Endometriosis
Combining Ultrasound and Biomarkers to Diagnose Superficial Endometriosis
Endometriosis is a benign gynecological disease characterized by uterine-like cells growing outside the uterus, leading to pain, infertility, and inflammation.
- Trial name
- SPGENDO (NCT05523284)
- Testing
- SonoPODography
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- McMaster University
Endometriosis
ENDOmetriosis Robotic Assisted Surgery
The purpose of this study is to compare the robot-assisted approach with the laparoscopic approach in terms of reducing the rates of intraoperative and postoperative complications in patients undergoing total hysterectomy for DIE…
- Trial name
- ENDO-RAS (NCT06445179)
- Testing
- Total Laparoscopic Hysterectomy, Ureterolysis
- Where
- 2 sites in France
- Volunteers
- 224 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Endometriosis, Deep Endometriosis
Ureteric Identification Using Indocyanine Green Dye Versus Conventional Ureteric Stenting to Reduce Post-operative Pain and Surgical Morbidity During Endometriosis Surgery
Endometriosis is a common (around 1 in 10 women), non-cancerous condition where tissue similar to the womb lining is found growing elsewhere, most commonly inside the pelvis.
- Trial name
- ICE (NCT06852248)
- Testing
- Ureteric stenting, Indocyanine green (ICG) dye
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University Hospitals of North Midlands NHS Trust
Endometriosis, Deep Endometriosis
Cohort of the Franco-European Multidisciplinary Institute of Endometriosis
Endometriosis is a chronic benign gynecological condition affecting 5 to 10% of women of reproductive age, often responsible for pelvic pain, digestive symptoms, and infertility, leading to a significant reduction in quality of…
- Conditions
- Endometriosis, Deep Endometriosis, Pelvic Pain
- Trial name
- IFEMEndo (NCT07243587)
- Testing
- OBSERVATIONAL
- Where
- France
- Volunteers
- 15,000 people
- Sponsor
- Clinique Tivoli Ducos
Endometriosis
TVUS vs MRI Efficacy in Diagnosis of Laparoscopically Managed Patients With DIE
The purpose of the study is to compare the reliability and accuracy of systematic ultrasonographic scanning using International Deep Endometriosis Analysis group approach versus magnetic resonance imaging (MRI) assessment in…
- Trial name
- NCT06821438
- Testing
- Laparoscopy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Endometriosis, Adenomyosis of Uterus
Artificial Intelligence Into Ultrasound Diagnostics in Reproductive Medicine
The goal of this observational study is to develop and validate artificial intelligence (AI)-based algorithms that support ultrasound diagnosis of endometriosis, adenomyosis, myometrial masses, uterine malformations, and impaired…
- Conditions
- Endometriosis, Adenomyosis of Uterus, Leiomyoma (Uterine Fibroids), Uterine Neoplasms
- Trial name
- AUDRIE (NCT07810920)
- Where
- Hungary
- Volunteers
- 1,600 people
- Sponsor
- Semmelweis University
Deep Endometriosis, Surgery
Imaging Comparison for the Preoperative Planning and Diagnosis of DIE: a Multicenter Retrospective Study.
Several centers in Belgium use both transvaginal ultrasound (TVS) and magnetic resonance imaging (MRI) for the preoperative diagnosis of deep infiltrating endometriosis (DIE), while other centers rely almost exclusively on TVS.
- Conditions
- Deep Endometriosis, Surgery, Transvaginal Ultrasound, MRI
- Trial name
- NCT06994091
- Where
- Belgium
- Volunteers
- 200 people
- Sponsor
- Ziekenhuis Oost-Limburg
Deep Endometriosis
Robotic Surgery in the Treatment of Deep Endometriosis: Da Vinci Vs HUGO RAS Comparison
The aim is to clarify whether both surgical approaches represent, equivalently, a good treatment for the management of patients with deep endometriosis who are candidates for surgery, or whether there are any differences between…
- Trial name
- NCT06781398
- Where
- 2 sites in Italy
- Volunteers
- 86 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Deep Infiltrating Endometriosis With or Without Bowel Involvement
Intraoperative Ultrasound in Bowel Deep Endometriosis
This study investigates the use of intraoperative transvaginal (IOTVUS) and/or endorectal ultrasound (IOERUS) in the surgical treatment of bowel deep infiltrating endometriosis (DIE).
- Trial name
- NCT06876376
- Testing
- intraoperative ultrasound for the assessment of bowel deep infiltrating endometriosis
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacion Dexeus
Indocyanine Green (ICG), Robotic Surgical Procedure
Assessing the Efficacy of Indocyanine Green for Ureter Identification During Robot-Assisted Surgery in Advanced-Stage Endometriosis
The goal of this side-randomized, self-controlled trial, 1-site study is to explore the efficacy of Indocyanine Green Fluorescence (ICG) for Intraoperative Ureter Identification During Robot-Assisted Single-Site Surgery in…
- Conditions
- Indocyanine Green (ICG), Robotic Surgical Procedure, Deep Infiltrating Endometriosis (DIE), Endometriosis Pelvic
- Trial name
- NCT07144904
- Testing
- Indocyanine Green (ICG)-Assisted Ureteral Identification, Standard Ureteral Identification without ICG
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Ovarian Endometrioma, Endometriosis
Histological Assessment of Tissue Penetration Depth of Argon Beam Coagulation in Ovarian Endometriomas
The goal of this clinical trial is to evaluate the depth of tissue penetration of Argon Beam Coagulation (ABC) during laparoscopic surgery for ovarian endometriomas.
- Trial name
- ENDO-ARGON (NCT07711743)
- Testing
- Argon Plasma Coagulation
- Where
- Switzerland
- Volunteers
- 50 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Molecular Markers of Fibrosis of Single Types of Endometriosis and Their Use in Predicting Disease Severity
Molecular Markes of Fibrosis of Endometriosis and Their Use in Predicting Disease Severity
The primary aim of the project is to analyse gene expression in individual types of ectopic endometrium (ovarian endometriosis, peritoneal endometriosis, deep infiltrating endometriosis) and compare it with gene expression in…
- Trial name
- MMF (NCT06020482)
- Testing
- Molecular markes of fibrosis of single types of endometriosis and their use in predicting disease severity
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- General University Hospital, Prague
Endometriosis, Deep Endometriosis
Robotic Versus Laparoscopic Surgery for Deep Endometriosis
The objective of this study is to examine whether robot-assisted laparoscopy is superior compared to conventional laparoscopy as regards to patient outcome.
- Conditions
- Endometriosis, Deep Endometriosis, Surgery
- Trial name
- ROBEndo (NCT05179109)
- Testing
- Minimally invasive surgery
- Where
- Finland
- Volunteers
- 70 people
- Sponsor
- University of Oulu
Endometriosis, Endometriosis Rectum
Clinical Impact of Ultrasound Diagnosis in Bowel Endometriosis
This retrospective single-centre study evaluates how accurately preoperative ultrasound detects bowel involvement in women with deep endometriosis, using surgical findings as the reference.
- Conditions
- Endometriosis, Endometriosis Rectum, Endometriosis Pelvic, Endometriosis Colon
- Trial name
- NCT07900698
- Testing
- preoperative transvaginal ultrasound
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Erasme University Hospital