Clinical trials: Deep Brain Stimulation
Deep Brain Stimulation, PARKINSON DISEASE (Disorder)
Cortical Network Modulation by Subthalamic Nucleus DBS
Deep brain stimulation of the subthalamic nucleus (STN DBS) in Parkinson's disease (PD) can provide substantial motor benefit yet can also produce unwanted mood and cognitive side effects.
- Trial name
- NCT04922411
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Deep Brain Stimulation
Evaluation of Advanced Imaging and Visualization for Clinical Deep Brain Stimulation
The objective of this project is to evaluate next generation visualization tools and surgical targeting models for clinical deep brain stimulation (DBS).
- Trial name
- NCT06191874
- Testing
- Standard-of-care (SOC) surgery plan, HoloDBS hypothetical surgery plan
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Duke University
Parkinson Disease, Deep Brain Stimulation
The Impact of Exercise on Subthalamic Nucleus Neural Activity in Parkinson's Disease
Fifteen PwPD who have undergone DBS surgery and utilize the Percept system will complete a FE and VE exercise session on a stationary cycle while Off antiparkinsonian medication.
- Trial name
- NCT05905302
- Testing
- Forced and Voluntary Exercise
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Jay Alberts
Parkinson Disease, DBS
Utilizing Neural Signatures and Virtual Reality to Advance DBS Programming
The project uses virtual reality technology to recreate situations that cause freezing of gait in individuals with Parkinson's disease.
- Conditions
- Parkinson Disease, DBS, Deep Brain Stimulation, Freezing of Gait
- Trial name
- NCT05103384
- Testing
- Virtual Reality Environment
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Cleveland Clinic
Parkinson's Disease, Deep Brain Stimulation
Dual-task Augmented Reality for PD DBS
The goal of this project is to evaluate the safety and preliminary effectiveness of utilizing a digital therapeutic, Dual-task Augmented Reality Treatment (DART) protocol, for the treatment of postural instability and gait…
- Trial name
- DART for DBS (NCT06418152)
- Testing
- Multi-modal treatment
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Jay Alberts
Parkinson Disease, Deep Brain Stimulation
Burst-Type Deep Brain Stimulation of the Subthalamic Nucleus in Parkinson's Disease
This is a study to evaluate Deep brain stimulation (DBS) burst-type electrical stimulation programming verses standard DBS programming.
- Trial name
- BURST (NCT05753449)
- Testing
- Baseline (or standard of care) DBS programming, Burst-type DBS electrical stimulation programming
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Allegheny Singer Research Institute (also known as Allegheny Health Network Research Institute)
Parkinson's Disease, Deep Brain Stimulation
Tandem DBS for Parkinson's Disease: A Pilot Study Utilizing STN/GPi + Hypothalamic Stimulation
Does dual hemispheric stimulation of the subthalamic nucleus (STN) and fornix/hypothalamus potentially improve cognitive function in patients with Parkinsons disease.
- Trial name
- NCT01563341
- Testing
- Deep brain stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Spasmodic Dysphonia, Laryngeal Dystonia
Thalamic Deep Brain Stimulation for Spasmodic Dysphonia- DEBUSSY Trial
Laryngeal Dystonia (LD), also commonly referred to as spasmodic dysphonia, is a neurological voice disorder characterized by involuntary dystonic contractions of the laryngeal muscles.
- Conditions
- Spasmodic Dysphonia, Laryngeal Dystonia, Deep Brain Stimulation
- Trial name
- NCT02558634
- Testing
- VIM Thalamic Deep Brain Stimulation ON, VIM Thalamic Deep Brain Stimulation OFF
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- University of British Columbia
Parkinson's Disease, Deep Brain Stimulation Surgery
Effects of Dexmedetomidine on Activity in the Subthalamic Nucleus
The purpose of this research study is to find out whether dexmedetomidine changes brain cell activity in the subthalamic nucleus (STN).
- Trial name
- NCT01721460
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Wisconsin, Madison