Clinical trials: Decidual Stromal Cells
Hemorrhagic Cystitis, Stem Cell Transplantation
A Double Blind Randomized Study Using Placenta Derived Decidual Stromal Cells for Hemorrhagic Cystitis
A prospective double blind randomized study comparing placenta derived decidual stromal cells with placebo for hemorrhagic cystitis after allogeneic hematopoietic cell transplantation.
- Conditions
- Hemorrhagic Cystitis, Stem Cell Transplantation, Decidual Stromal Cells
- Trial name
- NCT02174536
- Testing
- Decidual stromal cells
- Where
- Sweden
- Volunteers
- 20 people
- Sponsor
- Karolinska Institutet
Myelodysplastic/Myeloproliferative Neoplasm, Steroid Refractory GVHD
Decidual Stromal Cells to Treat Graft-vs-Host Disease After Stem Cell Transplant for Myelodysplastic Syndrome/Myeloproliferative Neoplasm
This is a single participant study of decidual stromal cells (DSC) for the treatment of steroid refractory graft-versus-host disease (GVHD) in a patient with myelodysplastic syndrome/myeloproliferative neoplasm (MDS/MPN).
- Conditions
- Myelodysplastic/Myeloproliferative Neoplasm, Steroid Refractory GVHD, Allogeneic Hematopoietic Cell Transplant
- Trial name
- DSC-SR (NCT04926194)
- Testing
- Decidual stromal cells (DSC)
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University Health Network, Toronto
Hemorrhagic Cystitis
A Pilot Study Using Placenta Derived Decidual Stromal Cells for Hemorrhagic Cystitis
The purpose of this study is to evaluate the safety and efficacy using placenta derived decidual stromal cell therapy for hemorrhagic cystitis after allogeneic hematopoietic cell transplantation.
- Trial name
- NCT02172963
- Testing
- Decidual Stromal Cell therapy
- Where
- Sweden
- Volunteers
- 12 people
- Sponsor
- Karolinska Institutet
Graft Vs Host Disease
A Randomized Phase II Study to Compare the Potential Long-Lasting Positive Effect of Decidual Stromal Cells to the Best Available Treatment in Graft Versus Host Disease
This is an academic open-label, phase II randomized study in patients with steroid resistant severe acute Graft versus host disease (GvHD) who have had allogeneic hematopoietic stem cell transplantation.
- Trial name
- NCT05132166
- Testing
- Drug or biologic - anti-thymocyte globulin (ATG), extracorporeal photopheresis (ECP), mTOR inhibitors (everolimus or sirolimus), vedolizumab, ruxolitinib., Decidual Stromal Cells
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University Health Network, Toronto
Acute Lung Injury, Decidual Stromal Cells
A Pilot Study Using Placenta Derived Decidual Stromal Cells for Toxicity and Inflammation With Special Focus to the Allogeneic Hematopoietic Cell Transplantation Setting
To evaluate safety and efficacy using decidual stromal cell therapy for toxicity and inflammation, with special focus on allogeneic hematopoietic cell transplantation patients.
- Conditions
- Acute Lung Injury, Decidual Stromal Cells, Stem Cell Transplantation, Inflammation
- Trial name
- NCT02175303
- Testing
- Decidual stromal cell therapy
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Graft vs Host Disease
Decidual Stromal Cells as Treatment for Acute Graft Versus Host Disease, a Phase 1-2 Study
The purpose of this study is to evaluate safety and efficacy using decidual stromal cell therapy for graft versus host disease after allogeneic hematopoietic stem cell transplantation.
- Trial name
- NCT02172937
- Testing
- Decidual Stromal Cells thawed in plasma, Decidual Stromal Cells thawed in human albumin
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Karolinska Institutet
COVID-19, Acute Respiratory Distress Syndrome
Study of Decidual Stromal Cells to Treat COVID-19 Respiratory Failure
This is a research study to see how safe and effective decidual stromal cells are in treating patients with respiratory failure (breathing problem where not enough oxygen is passed from the lungs into the blood) caused by…
- Trial name
- NCT04451291
- Testing
- Decidual Stromal Cells (DSC)
- Where
- 3 sites in Canada
- Volunteers
- 19 people
- Sponsor
- University Health Network, Toronto
Graft vs Host Disease
A Phase 2 Study Using Placenta Derived Decidual Stromal Cells for Graft Versus Host Disease
The purpose of this study is to evaluate the safety and efficacy using decidual stromal cell therapy for graft versus host disease after allogeneic hematopoietic stem cell transplantation.
- Trial name
- NCT02172924
- Testing
- Early Decidual stromal cell therapy, Late Decidual stromal cell therapy
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Karolinska Institutet