Clinical trials: Dacryocystitis; Chronic
Dacryocystorhinostomy, Hydroxybutyl Chitosan
Safety and Efficacy of Thermosensitive Hydroxybutyl Chitosan and 5-fluorouracil Assisted Endoscopic Dacryocystorhinostomy in the Treatment of Chronic Dacryocystitis
Endoscopic dacryocystorhinostomy (En-DCR) has the advantages of less surgical trauma, shorter time, less postoperative bleeding, faster recovery, and no skin scars.
- Conditions
- Dacryocystorhinostomy, Hydroxybutyl Chitosan, Fluorouracil, Chronic Dacryocystitis
- Trial name
- NCT06175676
- Testing
- Hydroxybutyl chitosan, 5-Fluorouracil, Gelatin Sponge Sheet
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Dacryocystitis; Chronic, Lacrimal Sac Space-occupying Lesions
Color Doppler Ultrasound in Lacrimal Sac Space-occupying Lesions
Dacryocystitis and nasolacrimal duct obstruction are the main common causes of epiphora. Dacryocystorhinostomy (DCR) is a widely used and effective treatment for dacryocystitis and nasolacrimal duct obstruction.
- Conditions
- Dacryocystitis; Chronic, Lacrimal Sac Space-occupying Lesions, Color Doppler Ultrasound, Computed Tomography
- Trial name
- NCT05500950
- Testing
- CDU and CT-DCG or CT examination
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Wenzhou Medical University
Dacryocystitis; Chronic
Nasolacrimal Sac Biopsy in Endoscopic Dacryocystorhinostomy
During dacryocystorhinostomy (DCR), the lacrimal sac wall biopsy is not routinely performed, but it is recommended if there is a suspicion of underlying disease other than preoperatively or intraoperatively chronic inflammation.
- Trial name
- NCT04793230
- Testing
- biopsying
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Dacryocystitis, Bacteriology
The Study of Bacteriology and Pathogen Drug Sensitivity of Chronic Dacryocystitis
An observational study was designed to research the bacteriology and pathogen drug sensitivity of chronic dacryocystitis in China and optimize antibiotic therapy.
- Trial name
- NCT03216642
- Testing
- bacterial culture and analysis
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Chronic Dacryocystitis
Absorbable Drug-Eluting Lacrimal Sac Stent for Recurrent Chronic Dacryocystitis
This study aims to evaluate the safety and effectiveness of an absorbable lacrimal sac drug-eluting stent placed at the osteotomy site during endoscopic endonasal dacryocystorhinostomy (E-DCR) in patients with recurrent chronic…
- Trial name
- NCT07499791
- Testing
- Absorbable Lacrimal Sac Drug-Eluting Stent, Conventional Ostium Packing with Budesonide Nasal Spray
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Beijing Tongren Hospital
Dacryocystitis, Dacryocystitis; Chronic
Examination of Lacrimal Sac and Nasal Mucosa Preparations Taken in Dacryocystorhinostomy Surgery of Patients With Nasolacrimal Duct Obstruction and Comparison of Clinical Groups With Each Other
The goal of this observational study is to investigate etiology and pathogenesis of nasolacrimal duct obstruction and dacryocystitis in different adult clinic groups.
- Conditions
- Dacryocystitis, Dacryocystitis; Chronic, Dacryocystorhinostomy, Epiphora
- Trial name
- NCT06810089
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Uludag University
Chronic Dacryocystitis
The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy
To study the effect of Photosensitive hydrogel used for suture free anastomosis of lacrimal cyst and nasal mucoperiosteal flap in endoscopic nasal dacryocystostomy, and evaluate its adhesion to lacrimal cyst and nasal…
- Trial name
- NCT06551766
- Testing
- Photosensitive hydrogel, 6-0 absorbable stitches
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eye & ENT Hospital of Fudan University