Clinical trials: Dacryocystitis
Blepharitis, Conjunctivitis
Evaluation and Treatment of Patients With Corneal and External Diseases
This study offers evaluation and treatment for patients with certain corneal and external diseases of the eye (diseases of the surface of the eye and its surrounding structures).
- Conditions
- Blepharitis, Conjunctivitis, Corneal Disease, Dacryoadenitis
- Trial name
- NCT00008541
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- National Eye Institute (NEI)
Dacryocystitis, Bacteriology
The Study of Bacteriology and Pathogen Drug Sensitivity of Chronic Dacryocystitis
An observational study was designed to research the bacteriology and pathogen drug sensitivity of chronic dacryocystitis in China and optimize antibiotic therapy.
- Trial name
- NCT03216642
- Testing
- bacterial culture and analysis
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Dacryocystitis
Analgesic Efficacy of Pre-operative Oral Pregabalin in Dacryocystorhinostomy Surgery
This study is conducted to evaluate the effects of preoperative oral pregabalin on postoperative pain and analgesic requirements in patients undergoing DCR surgery.
- Trial name
- NCT05455944
- Testing
- Pregabalin 150mg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sameh Fathy
Epiphora, Dacryostenosis
Does Topical Ophthalmic Anesthetic Prior to Probing and Irrigation Decrease Pain?
Purpose: It is unknown whether instillation of a drop of anesthetic ophthalmic solution into the eye such as proparacaine hydrochloride 0.5% prior to probing and irrigation of the tear duct (lacrimal drainage) system improves…
- Conditions
- Epiphora, Dacryostenosis, Dacryocystitis
- Trial name
- NCT04229771
- Testing
- Proparacaine Hydrochloride ophthalmic solution, USP 0.5%, Balanced salt solution
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Corewell Health East
Dacryocystorhinostomy, Hydroxybutyl Chitosan
Safety and Efficacy of Thermosensitive Hydroxybutyl Chitosan and 5-fluorouracil Assisted Endoscopic Dacryocystorhinostomy in the Treatment of Chronic Dacryocystitis
Endoscopic dacryocystorhinostomy (En-DCR) has the advantages of less surgical trauma, shorter time, less postoperative bleeding, faster recovery, and no skin scars.
- Conditions
- Dacryocystorhinostomy, Hydroxybutyl Chitosan, Fluorouracil, Chronic Dacryocystitis
- Trial name
- NCT06175676
- Testing
- Hydroxybutyl chitosan, 5-Fluorouracil, Gelatin Sponge Sheet
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University Eye Hospital
Chronic Dacryocystitis
Absorbable Drug-Eluting Lacrimal Sac Stent for Recurrent Chronic Dacryocystitis
This study aims to evaluate the safety and effectiveness of an absorbable lacrimal sac drug-eluting stent placed at the osteotomy site during endoscopic endonasal dacryocystorhinostomy (E-DCR) in patients with recurrent chronic…
- Trial name
- NCT07499791
- Testing
- Absorbable Lacrimal Sac Drug-Eluting Stent, Conventional Ostium Packing with Budesonide Nasal Spray
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Beijing Tongren Hospital
Epiphora, Dacryocystitis
Comparative Study Between Wide and Narrow Fenstrum Endoscopic DCR
The aim of the study is to compare the efficacy and effectiveness of Endoscopic Endonasal DCR with narrow fenstrum approach and Endoscopic Endonasal DCR with wide fenstrum approach .
- Conditions
- Epiphora, Dacryocystitis, Dacryocystocele
- Trial name
- NCT04833452
- Testing
- Endoscopic dacryocystorhinostomy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Menoufia University
Glaucoma, Diabetic Retinopathy (DR)
"My Eyes, My Light": Amar Chokh, Amar Alo
Eye disease affects 2.2 billion people globally, which in turn adversely affects schooling, economic productivity, and participation in social life.
- Conditions
- Glaucoma, Diabetic Retinopathy (DR), Hypertensive Retinopathy, Cataract
- Trial name
- ACA2 (NCT07135570)
- Testing
- Multimodal Screening for Eye Disease, cataract surgery
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Data Yakka, Inc.
Lacrimal Apparatus Diseases, Dacryocystitis
Follow up of Nasolacrimal Intubation in Adults
For patients with chronic epiphora, Dacryocystorhinostomy is currently the gold standard treatment, with a success rate of 80-90% according to literature.
- Trial name
- NCT00706251
- Testing
- Silicone tube
- Where
- Israel
- Volunteers
- 180 people
- Sponsor
- Shaare Zedek Medical Center
Dacryocystitis, Dacryocystitis; Chronic
Examination of Lacrimal Sac and Nasal Mucosa Preparations Taken in Dacryocystorhinostomy Surgery of Patients With Nasolacrimal Duct Obstruction and Comparison of Clinical Groups With Each Other
The goal of this observational study is to investigate etiology and pathogenesis of nasolacrimal duct obstruction and dacryocystitis in different adult clinic groups.
- Conditions
- Dacryocystitis, Dacryocystitis; Chronic, Dacryocystorhinostomy, Epiphora
- Trial name
- NCT06810089
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Uludag University
Epiphora, Dacryostenosis
Does Topical Ophthalmic Proparacaine 0.5% Prior to Probing and Irrigation Decrease Pain?
Purpose: It is unknown whether instillation of a drop of anesthetic ophthalmic solution into the eye such as proparacaine hydrochloride 0.5% prior to probing and irrigation of the tear duct (lacrimal drainage) system improves…
- Conditions
- Epiphora, Dacryostenosis, Dacryocystitis
- Trial name
- NCT05663684
- Testing
- Proparacaine Hydrochloride ophthalmic solution, USP 0.5%, Balanced salt solution
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Neonatal Dacryocystitis, Congenital Nasolacrimal Duct Obstruction
Efficacy and Safety of Piclosept in the Complex Treatment of Neonatal Dacryocystitis
This single-center, prospective, randomized, controlled, assessor-blinded study will evaluate the efficacy and safety of Piclosept® ophthalmic solution as an adjunct to standardized lacrimal sac massage in children aged 1 to 12…
- Trial name
- NCT07875517
- Testing
- Picloxidine, Levofloxacin, Standardized lacrimal sac massage
- Where
- Kazakhstan
- Volunteers
- 90 people
- Sponsor
- Kazakh Eye Research Institute
Dacryocystitis
The Microbiological Spectrum in Acute Dacryocystitis
Acute dacryocystitis in adults can be a very painful disease and may not respond well to medical therapy. The purpose of this prospective non-randomised study is to determine the microorganisms causing acute dacryocystitis and…
- Trial name
- NCT00349297
- Where
- Singapore
- Sponsor
- Singapore National Eye Centre
Dacryocystitis
Hyaluronic Acid vs Mitomycin-C in External Dacryocystorhinostomy
RCT to compare the surgical success in patients undergoing external dacryocystorhinostomy with intraoperative Mitomycin-C (0.4 mg/ml) Vs Hyaluronic acid 1% (1ml) as adjuvant, To compare the complication rates and wound healing…
- Trial name
- HAM-DCR (NCT07504250)
- Testing
- Hyaluronic Acid (HA), Mitomycin -C
- Volunteers
- 36 people
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Chronic Dacryocystitis
The Application of Photosensitive Hydrogel in Intranasal Endoscopic Dacryocystorhinostomy
To study the effect of Photosensitive hydrogel used for suture free anastomosis of lacrimal cyst and nasal mucoperiosteal flap in endoscopic nasal dacryocystostomy, and evaluate its adhesion to lacrimal cyst and nasal…
- Trial name
- NCT06551766
- Testing
- Photosensitive hydrogel, 6-0 absorbable stitches
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Dacryocystitis; Chronic
Nasolacrimal Sac Biopsy in Endoscopic Dacryocystorhinostomy
During dacryocystorhinostomy (DCR), the lacrimal sac wall biopsy is not routinely performed, but it is recommended if there is a suspicion of underlying disease other than preoperatively or intraoperatively chronic inflammation.
- Trial name
- NCT04793230
- Testing
- biopsying
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Al-Azhar University
Dacryocystitis
Efficacy of Mitomycin C in Endoscopic Dacryocystorhinostomy: A Systematic Review and Meta-Analysis
To assess the efficacy and safety of local application of intraoperative mitomycin C (MMC) at osteotomy site in endoscopic dacryocystorhinostomy(EN-DCR).
- Trial name
- NCT01772277
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Yifan Feng
Dacryocystitis; Chronic, Lacrimal Sac Space-occupying Lesions
Color Doppler Ultrasound in Lacrimal Sac Space-occupying Lesions
Dacryocystitis and nasolacrimal duct obstruction are the main common causes of epiphora. Dacryocystorhinostomy (DCR) is a widely used and effective treatment for dacryocystitis and nasolacrimal duct obstruction.
- Conditions
- Dacryocystitis; Chronic, Lacrimal Sac Space-occupying Lesions, Color Doppler Ultrasound, Computed Tomography
- Trial name
- NCT05500950
- Testing
- CDU and CT-DCG or CT examination
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Wenzhou Medical University