Clinical trials: DDP
Defensive Medicine
Defensive Dentistry Practices and Dentists (DDP)
Medical malpractice claims have been on the rise in recent years due to the growing patient rights movement. This term is defined as an injury caused by a healthcare professional's failure to follow standard practice during…
- Trial name
- NCT06500832
- Testing
- Survey-based Data Collection Tool
- Where
- Turkey (Türkiye)
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Nasopharyngeal Carcinoma
Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
This is a Phase II Randomized Trial to Compare Paclitaxel combined with DDP Plus Concurrent Chemoradiotherapy With DDP Plus Concurrent Chemoradiotherapy in Patients With Locoregionally Advanced Nasopharyngeal Carcinoma
- Trial name
- NCT03047265
- Testing
- Paclitaxel, Cisplatin
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Sun Yat-sen University
Head and Neck Neoplasms
After Induction Chemotherapy of DP Plus DDP Concurrent Radiotherapy With and Without Bevacizumab Study
This is a randomized, open controlled multicenter phase II clinical study. The SPSS statistical software estimation of sample size, selection of the initial treatment of locally advanced head and neck squamous cell carcinoma in…
- Trial name
- NCT02047487
- Where
- 2 sites in China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Esophageal Squamous Cell Carcinoma
Paclitaxel and DDP Combined With Anlotinib in the First-line Treatment for Patients With Advanced Esophageal Squamous Cell Carcinoma（ESCC）.
To evaluate the efficacy and safety of paclitaxel and DDP combined with Anlotinib in the treatment of advanced esophageal squamous cell carcinoma.
- Trial name
- NCT04063683
- Testing
- Anlotinib Hydrochloride, Paclitaxel, cisplatin
- Where
- 6 sites in China
- Volunteers
- 47 people
- Sponsor
- Henan Cancer Hospital
Rectal Squamous Cell Carcinoma
Radical Concurrent Chemoradiotherapy With DDP/5-FU and PD-1 Antibody for Non-metastatic Rectal Squamous Cell Carcinoma
The goal of this clinical trial is to learn if PD-1 monoclonal antibody combined with radical chemoradiotherapy works to treat rectal squamous cell carcinoma (rSCC). lt will also learn about the safety of the regime.
- Trial name
- NCT06364384
- Testing
- PD-1 and CRT
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Mental Health, Psychiatric Problems
Relationships in Good Hands - Clinical and Cost-effectiveness of Dyadic Developmental Psychotherapy
The research question is: Can the research recommend better ways for social care and health services to work work together to help adoptive and foster families? Can a therapy called DDP improve the mental health of 5-12 year old…
- Conditions
- Mental Health, Psychiatric Problems, Child Neglect, Maltreatment
- Trial name
- RIGHT (NCT04187911)
- Testing
- Dyadic Developmental Psychotherapy (DDP), Services as Usual (SAU)
- Where
- 16 sites in United Kingdom
- Volunteers
- 240 people
- Sponsor
- University of Glasgow
Pancreatic Neoplasm
DDP ip Combined With AG in PDAC With Peritoneal Metastasis
intraperitoneal (IP) Cisplatin combined with intravenous gemcitabine + nab-paclitaxel in patients with pancreatic cancer with peritoneal metastasis
- Trial name
- NCT05222204
- Testing
- intraperitoneal (IP) Cisplatin combined with intravenous gemcitabine + nab-paclitaxel
- Where
- 2 sites in China
- Volunteers
- 91 people
- Sponsor
- Fudan University
Psychiatric Problem, Child Neglect
Implementing Dyadic Developmental Psychotherapy (DDP) - Evaluation Research
The objective of this study is to evaluate the implementation and use of Dyadic Developmental Psychotherapy (DDP) in three centra, with particular focus on its potential effects on the quality of the observable caregiver-child…
- Conditions
- Psychiatric Problem, Child Neglect, Maltreatment, Child Behavior Problem
- Trial name
- NCT04763720
- Testing
- Dyadic Developmental Psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sykehuset Telemark
Advanced Esophageal Carcinoma
mFOLFIRI as the Second Line Chemotherapy for Advanced Esophageal Carcinoma After Failure of 1st Line Treatment of Paclitaxel/DDP : a Phase II Single Center Prospective Clinical Trial
There are few studies about 2nd line treatment in advanced esophageal carcinoma(AEC), some showed that irinotecan may be effective.
- Trial name
- NCT01044420
- Testing
- mFOLFIRI
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University
Esophageal Squamous Cell Carcinoma
Radiotherapy Combined With S-1/DDP for Elderly Esophageal Squamous Cell Cancer.
This Prospective, single-arm Phase Ⅱ study is to determine the efficacy and safety of Once-daily Simultaneous Modulated Accelerated Radiotherapy combined with S-1/DDP for geratic esophageal squamous cell carcinoma patients.
- Trial name
- NCT02606916
- Testing
- SMART, DDP, S-1
- Where
- China
- Volunteers
- 42 people
- Sponsor
- Sun Yat-sen University
HER2-negative Breast Cancer, Neoadjuvant Chemotherapy
Efficacy and Safety of Dose-dense Chemotherapy (ddEC-ddP) for Neoadjuvant Chemotherapy of HER2-negative Breast Cancer
Recent clinical studies showed that breast cancer patients especially for those with lymph node metastasis may benefit from dose-dense chemotherapy, like adriamycin and cyclophosphamide (AC) q2w×4→ paclitaxel (P) q2w×4.
- Trial name
- NCT04576143
- Testing
- Epirubicin, Cyclophosphamid, Docetaxel
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Treatment 1:Dialectical Behavior Therapy (DBT), Treatment 2:Dynamic Deconstructive Psychotherapy (DDP)
Assessment of Cost-effectiveness in Two Empirically-based Psychotherapies for Borderline Personality Disorder: A Randomized Controlled Trial
Patients suffering from borderline personality disorder (BPD) are considered frequent utilizers of psychiatric emergency rooms and of psychiatric hospitalizations.
- Conditions
- Treatment 1:Dialectical Behavior Therapy (DBT), Treatment 2:Dynamic Deconstructive Psychotherapy (DDP), Placebo
- Trial name
- NCT04309045
- Testing
- DBT, DDP, control group
- Volunteers
- 60 people
- Sponsor
- Shalvata Mental Health Center
DDP, Head and Neck Cancer
Efficacy of Trans-tympanic Injections of a Sodium Thiosulfate Gel to Prevent Cisplatin-induced Ototoxicity
This study evaluates whether a gel containing sodium thiosulfate deposited via a trans-tympanic injection on the round window of the middle ear could reduce the ototoxicity caused by the drug Cisplatin among patients with head…
- Conditions
- DDP, Head and Neck Cancer, Adverse Effect
- Trial name
- STS001 (NCT02281006)
- Testing
- Trans-tympanic injection of a sodium thiosulfate gel
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- CHU de Quebec-Universite Laval
Locally Advanced Nasopharyngeal Carcinoma
GP Induction Chemotherapy us TPF Adjuvant Chemotherapy Combined With DDP Concurrent Chemoradiotherapy in the Treatment of Locally Advanced NPC
Through randomized controlled phase III multicenter clinical trials, GP induction chemotherapy vs TPF regimen adjuvant chemotherapy combined with DDP concurrent chemoradiotherapy for the treatment of locally advanced…
- Trial name
- NCT03604965
- Testing
- GP+CCRT, TPF+CCRT
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Guiyang Medical University
Esophageal Squamous Cell Carcinoma
Endostar Combined With NVB and DDP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas
The aim of this study is to explore whether endostar combined with NVB and DDP as treatment could improve progression-free surial time (PFS) and to evaluate the safety of the chemotherapy regimens
- Trial name
- NCT02665702
- Testing
- NVB, DDP, Endostar
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Fudan University
Stimulant Use
Drugs Brain and Behavior (DDP)
In this project, we will examine individual differences in the effects of a stimulant drug, methamphetamine (MA), on mesolimbic reward function using fMRI.
- Trial name
- DDP (NCT04642820)
- Testing
- Methamphetamine
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- University of Chicago