Clinical trials: D-dimer
Pathologic Fibrinolysis
Fibrinolysis Before Cardiopulmonary Bypass?
It is common practice to use antifibrinolytic agents before and during cardiopulmonary bypass. They are not without side effects.
- Trial name
- NCT01981863
- Testing
- Epsilonaminocaproic acid
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stanford University
Venous Thromboembolism
D-dimer to Predict Recurrence in Patients With Multiple Episodes of Venous Thromboembolism
Optimal duration of oral anticoagulant therapy in patients with recurrent episodes of venous thromboembolism (VTE) is a matter of debate and recommendations are based on inadequate evidence.
- Trial name
- NCT00428441
- Testing
- Warfarin
- Where
- Italy
- Volunteers
- 73 people
- Sponsor
- Università degli Studi dell'Insubria
HIV
Attenuation of D-dimer Using Vorapaxar to Target Inflammatory and Coagulation Endpoints
ADVICE is a randomised, international, double-blind, placebo-controlled trial. The purpose of the ADVICE study is to compare the safety and efficacy of vorapaxar in reducing d-dimer expression and markers of cellular immune…
- Trial name
- ADVICE (NCT02394730)
- Testing
- vorapaxar
- Where
- 7 sites in United States, Australia
- Volunteers
- 65 people
- Sponsor
- Kirby Institute
Covid19
Assessing Safety, Hospitalization and Efficacy of rNAPc2 in COVID-19
Sequential randomized, multicenter, active comparator study to evaluate the hypothesis that rNAPc2 (AB201), a novel, potent and highly selective tissue factor inhibitor with anticoagulant, anti-inflammatory and potential…
- Trial name
- ASPEN (NCT04655586)
- Testing
- rNAPc2, Heparin
- Where
- 24 sites in United States, Argentina and 1 more
- Volunteers
- 160 people
- Sponsor
- ARCA Biopharma, Inc.
Heart Valve Disease
D-Dimer Determined Anticoagulation INTENSITY in Patients With Mechanical Valve Replacement
The optimal intensity of oral anticoagulation in China patients undergoing mechanical valve replacements is still controversial due to the different risk profiles of thrombophilia and bleeding in Chinese patients.
- Trial name
- 3D-INTENSITY (NCT01996657)
- Testing
- Warfarin
- Where
- 2 sites in China
- Volunteers
- 772 people, healthy volunteers welcome
- Sponsor
- Wuhan Asia Heart Hospital
Thrombosis
Sickle Cell Trait and the Risk of Venous Thromboembolism
The purpose of this trial is to investigate D-Dimer levels, a surrogate marker of venous thromboembolism, in pregnant/postpartum white women as compared to pregnant/postpartum black women, and pregnant/postpartum women with…
- Trial name
- SCT&DVT (NCT01148940)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Atrial Fibrillation
D-dimer Assay for the Exclusion of Intra-atrial Thrombus Risk Before Ablation of Atrial Fibrillation
The purpose of this study is to determine whether D-dimer dosage allow to exclude risk of intraatrial thrombus before performing an ablation of atrial fibrillation
- Trial name
- NCT02199080
- Testing
- D-dimer assay before ablation of atrial fibrillation
- Where
- 37 sites in France
- Volunteers
- 2,506 people
- Sponsor
- Groupe Hospitalier de la Rochelle Ré Aunis
Gall Stone Disease, Polyp
Comparison of Coagulation Factors During Laparoscopic Cholecystectomy
Pneumoperitoneum is formed with CO2 during laparoscopic abdominal operations. Effect of pneumoperitoneum on coagulation factors is not well known.
- Trial name
- NCT02568852
- Testing
- Combined anaesthesia, General anaesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Lütfiye Nuri Burat Government Hospital
Pulmonary Embolism
Breath Analysis Technique to Diagnose Pulmonary Embolism
A pulmonary embolism (PE) is a blockage in one of the arteries of the lungs, and is usually caused by a traveling blood clot. The D-dimer blood test is currently used to diagnose PEs, but it is not always accurate for individuals…
- Trial name
- NCT00368836
- Testing
- BreathScreen PE
- Where
- United States
- Volunteers
- 475 people
- Sponsor
- Wake Forest University Health Sciences