Clinical trials: Cutaneous Sarcoidosis
Sarcoidosis
SARCOTHAL. Thalidomide in Skin Sarcoidosis
Sarcoidosis is a multisystem disease involving most frequently the lung, the eyes, the lymph nodes and the skin. Skin lesions may be disfiguring and impair the quality of life.
- Trial name
- NCT00305552
- Testing
- THALIDOMIDE
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sarcoidosis, Cutaneous Sarcoidosis
Efficacy Study of Humira in the Treatment of Cutaneous Sarcoidosis
The purpose of this study is to determine the safety and efficacy of Humira in the treatment of cutaneous sarcoidosis.
- Trial name
- NCT00731757
- Testing
- Humira
- Where
- United States
- Sponsor
- Wright State University
Sarcoidosis, Cutaneous Sarcoidosis
ACTHAR Gel for Cutaneous Sarcoidosis: An Open Label Trial
ACTHAR gel has efficacy in the treatment of cutaneous sarcoidosis
- Trial name
- NCT02348905
- Testing
- ACTHAR Gel 40 units twice weekly, ACTHAR Gel 80 units twice weekly.
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Albany Medical College
Cutaneous Sarcoidosis
A Study of Brepocitinib in Adults With Cutaneous Sarcoidosis
This study will evaluate the clinical safety and efficacy of oral brepocitinib in participants with cutaneous sarcoidosis.
- Trial name
- BEACON (NCT06978725)
- Testing
- Oral Brepocitinib
- Where
- 39 sites in United States
- Volunteers
- 168 people
- Sponsor
- Priovant Therapeutics, Inc.
Cutaneous Sarcoidosis, Granuloma Annulare
Open-label Trial of Tofacitinib in Cutaneous Sarcoidosis and Granuloma Annulare
To investigate the ability of tofacitinib, a Janus kinase (JAK) inhibitor, to treat patients with cutaneous sarcoidosis and granuloma annulare during 6 months of therapy.
- Trial name
- NCT03910543
- Testing
- Tofacitinib 5 mg twice daily
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Yale University
Sarcoidosis, Cutaneous Sarcoidosis
The Efficacy and Safety of CC-10004 in Chronic Cutaneous Sarcoidosis
To determine whether CC-10004, a phosphodiesterase inhibitor, is useful in treating chronic cutaneous sarcoidosis.
- Trial name
- NCT00794274
- Testing
- CC-100004
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Cincinnati
Sarcoidosis
Trial of Antimycobacterial Therapy in Sarcoidosis
Growing research from independent laboratories provide an association between mycobacteria and sarcoidosis. More recent immunologic and molecular studies demonstrate immune responses to mycobacteria virulence factors.
- Trial name
- CLEAR (NCT01074554)
- Testing
- Antibiotic Regimen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Vanderbilt University
Sarcoidosis, Pulmonary, Sarcoidosis Skin
the PHENOSAR Trial: Use of Antibiotics in Treatment of Sarcoidosis
In this study it is investigated whether treatment with azithromycin in combination with doxycycline reduces the bacterial load of C.
- Trial name
- NCT05291468
- Testing
- FDG-PET/CT
- Where
- Netherlands
- Volunteers
- 40 people
- Sponsor
- St. Antonius Hospital
Sarcoidosis
A Phase 2 Study With CC-220 in Skin Sarcoidosis
This study will evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of oral CC-220 in adult subjects with chronic cutaneous sarcoidosis.
- Trial name
- NCT02192489
- Testing
- CC-220 0.3 mg Daily, CC-220 0.6mg Daily
- Sponsor
- Celgene
Sarcoidosis
Study to Determine the Efficacy of Adalimumab in the Treatment of Cutaneous Sarcoidosis
The purpose of the study is to see if Humira is effective and safe in the treatment of sarcoidosis.
- Trial name
- NCT00690911
- Testing
- adalimumab
- Where
- United States
- Sponsor
- Wake Forest University
Sarcoidosis, Granuloma Annulare
Tyrosine Kinase 2 (TYK2) for GA and CS
To investigate the role of an oral TYK2 inhibitor for the treatment of patients with moderate to severe sarcoidosis with cutaneous involvement (CSAMI score of 10 or greater) and GA (defined as a BSA involvement of at least 5%)…
- Trial name
- NCT06725264
- Testing
- Deucravacitinib
- Where
- United States
- Sponsor
- Yale University
Sarcoidosis, Cutaneous Sarcoidosis
Sirolimus in Cutaneous Sarcoidosis
Sarcoidosis is a multisystemic disease of unknown etiology characterized by the presence of epithelioid granulomas without caseous necrosis in the organs involved. Sarcoidosis cutaneous lesions can be severe.
- Trial name
- SIRIUS (NCT05458492)
- Testing
- Sirolimus
- Volunteers
- 10 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Sarcoidosis
A Study of Adalimumab to Treat Sarcoidosis of the Skin
The purpose of this study is to determine if adalimumab is an effective for the skin manifestations of sarcoidosis.
- Trial name
- NCT00274352
- Testing
- adalimumab
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Pariser, Robert J., M.D.
Sarcoidosis
A Study to Evaluate the Safety and Effectiveness of Ustekinumab or Golimumab Administered Subcutaneously (SC) in Patients With Sarcoidosis
This study tests the safety and effectiveness of ustekinumab or golimumab compared to placebo (placebo looks like the drugs being studied, but has no active ingredients).
- Trial name
- NCT00955279
- Testing
- Golimumab, Ustekinumab
- Where
- 53 sites in United States, Belgium and 7 more
- Volunteers
- 173 people
- Sponsor
- Centocor, Inc.