Clinical trials: Cosmetic Skin
Skin Care
A Study to Assess the Local Cutaneous and Ocular Tolerance of Three Developmental Facial Skin-care Formulations.
This study aims to determine the local cutaneous and ocular tolerance of 3 developmental skin-care products; a serum, a lotion, and a cream in healthy female subjects with clinically evaluated sensitive facial skin for 21 days.
- Trial name
- NCT04557371
- Testing
- Serum, Lotion, Cream
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Healthy
Clinical Study for the Evaluation of the Depigmenting Activity of a Cosmetic Product on Spotted Hand Skin
Aim of the study was to evaluate by instrumental measurements the depigmenting activity of a cosmetic treatment for spotted hand skin; in particular it was investigated the synergic activity of an emulsion, with…
- Trial name
- NCT02204436
- Testing
- Emulsion and gel
- Where
- Italy
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Derming SRL
Acne Vulgaris
Assess the Effects and the Tolerance of Cosmetic Product in the Follow-up Phase of Facial Acne for 1 Year
Acne is a chronic inflammatory disease of the pilo-sebaceous unit in the skin. Indeed, your skin is covered with tiny holes called hair follicles, or pores.
- Trial name
- NCT04301063
- Testing
- RV3278A
- Where
- 8 sites in France, Italy and 1 more
- Volunteers
- 54 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Mastectomy; Lymphedema, Breast Cancer
Examining and Comparing the Temporal Changes and Results of Cosmetic, Quality of Life and Patient Satisfaction Achieved With Immediate and Delayed-immediate Implant-based Breast Reconstruction Procedures and Contralateral Symmetrization Techniques
This is a response-adaptive (RAR) prospective randomized study with a long-term follow-up and the aim of this clinical study is to measure with qualitative and quantitative indicators the changes in cosmetic results, quality of…
- Conditions
- Mastectomy; Lymphedema, Breast Cancer, Quality of Life
- Trial name
- NCT04356235
- Testing
- A: expander-silicone implant exchange and contralateral symmetrization with mastopexy and if needed with volume reduction, B: expander-silicone implant exchange with contralateral symmetrization with mastopexy and Ultrapro sling, C: expander-silicone implant exchange and contralateral symmetrization with mastopexy and silicone implant augmentation
- Where
- Hungary
- Volunteers
- 528 people, healthy volunteers welcome
- Sponsor
- National Institute of Oncology, Hungary
Skin Quality
Evaluation of Skin Quality Improvement
The purpose of this study is to comprehensively investigate and objectively demonstrate the effectiveness of hyperdiltue Botox® Cosmetic in improving overall skin quality, more specifically evenness of skin tone, reduction of…
- Trial name
- NCT03097835
- Testing
- Hyper-Diluted Botox, Topical anesthesia, 0.9% saline solution
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Steve Yoelin M.D. Medical Associates, Inc.
Hyperkeratosis, Callus
Ultrasonographic Evaluation of Cosmetic Keratolytic Treatment of Foot Calluses and Corns
This prospective, non-randomized, controlled study evaluated the efficacy of a topical cosmetic keratolytic preparation (serum and cream containing urea, salicylic acid, and collagen) in reducing the thickness and associated pain…
- Conditions
- Hyperkeratosis, Callus, Corn (Clavus), Foot Dermatoses
- Trial name
- NCT07765225
- Testing
- Topical Keratolytic Cosmetic (Serum + Cream)
- Where
- Poland
- Volunteers
- 124 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Breast Cancer
RAPID: Randomized Trial of Accelerated Partial Breast Irradiation
To determine if Accelerated Partial Breast Irradiation, using 3D CRT, is as effective as Whole Breast Irradiation following breast conserving surgery in women with an new histological diagnosis of ductal carcinoma in situ only or…
- Trial name
- NCT00282035
- Testing
- APBI utilizing 3D-CRT radiation, Whole breast irradiation
- Where
- 33 sites in Australia, Canada and 1 more
- Volunteers
- 2,135 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Cesarean Section; Infection, Scar
Evaluation of Wound Infection Rates and Cosmetic Results of Different Suture Materials in Cesarean Skin Incision
Our primary aim is to determine the most beneficial suture in order to reduce complications due to skin incision in common surgeries such as cesarean section, and our secondary aim is to evaluate the suture material used in terms…
- Trial name
- NCT06119113
- Testing
- Evaluation of the wound infection at the 10th day post-op check-up among all groups, Evaluation of the cosmetic results of the incision line at the 2nd month post-op check-up among all groups, Evaluation of the cosmetic results of the incision line at the 6th month post-op check-up among all groups
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ayşenur Çalış Özbayram
Healthy Skin
Skin Cell Regeneration Efficacy of Cosmetic Product
The objective of the study is to investigate the effect of one cosmetic product (exfoliator) containing Mitopure on the skin cell regeneration as well as on the skin hydration and skin barrier function in comparison to an…
- Trial name
- Exfoliator (NCT07096466)
- Testing
- DHA stain, No DHA stain, Cosmetic product application - forearm
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Healthy
Safety of Serum for Post-Inflammatory on Hyperpigmentation Skin
This study aims to investigate the safety of serum product containing low dose of alpha hydroxy acid (AHA) i.e. 1% Glycolic acid and Lactic acid and Polyglutamate acid derivatives (PGA) for post-inflammatory hyperpigmentation…
- Trial name
- NCT05998200
- Testing
- Serum with low concentration AHA (1% Glycolic acid and Lactic acid) and PGA
- Where
- Malaysia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- USMARI Research & Innovation Centre
Breast Cancer
Quality of Life and Cosmetic Outcomes of Breast-Conserving Surgery According to Localization Method
The goal of this clinical trial is to compare Quality of Life and cosmetic outcomes in Breast Conservative Carcer surgery depending on localization method (intraoperative Ultrasound, wire and radioactive seed).
- Trial name
- TRIGUIDE (NCT06186011)
- Testing
- Wire-guided surgery, Radioactive seed localization, Intraoperative ultrasound localization
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- Hospital Clinic of Barcelona
Facial Skin Hydration, Skin Rejuvenation
Comparison of KIRA Hydrating Treatment and Jet Peel for Facial Skin Hydration
This study compared the effects and tolerability of two non-invasive facial treatment systems on skin hydration: a hydroabrasion-jet system (KIRA) and a conventional high-pressure jet system (JET PEEL).
- Trial name
- NCT07793149
- Testing
- Vacuum-Assisted Hydroabrasion, High-Pressure Jet Infusion, Jet Infusion at 5 Bar
- Where
- 2 sites in Serbia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Faculty of Pharmacy Novi Sad
Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms
Evaluation of a Cosmetic Product to Preserve Skin Conditions When Using Anti-EGFR Cancer Therapies
It is important for patients treated with anti-EGFR therapies to get access to cosmetic options to preserve their skin condition during treatment.
- Conditions
- Carcinoma, Non-Small-Cell Lung, Colorectal Neoplasms, Head and Neck Neoplasms
- Trial name
- OPERA (NCT04878692)
- Testing
- Application of Onco-Rash cream, Application of Onco-Neutre cream
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Hospices Civils de Lyon
Breast Cancer
Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients
In this ABLATIVE-2 trial, low-risk breast cancer patients will be treated with MRI-guided single dose preoperative partial breast radiotherapy to assess the rate of pathologic complete response after an interval of six to twelve…
- Trial name
- ABLATIVE-2 (NCT05350722)
- Testing
- Single dose ablative radiotherapy
- Where
- 7 sites in Australia, Netherlands
- Volunteers
- 100 people
- Sponsor
- Amsterdam UMC, location VUmc
Breast Fibrosis, Breast Cancer
An Integrated Optimization of Surgery and Radiotherapy Techniques to Improve Cosmetic Outcome and Quality of Life in Breast Conserving Therapy for Breast Cancer Patients (STARLINGS Study)
To assess the role of different combinations of (oncoplastic) surgery and radiotherapy techniques as risk factors for moderate to severe fibrosis and for moderate to poor cosmetic outcome.
- Conditions
- Breast Fibrosis, Breast Cancer, Breast Cancer Female, Breast Neoplasms
- Trial name
- STARLINGS (NCT05263362)
- Testing
- no intervention
- Where
- 4 sites in Netherlands
- Volunteers
- 775 people
- Sponsor
- Erasmus Medical Center
Cosmetics Product Effects
Cosmetic Products and Facial Skin Microbiome
The skin microbiome diversity in female healthy volunteers will be studied along with cosmetic products application in 1 month period.
- Trial name
- NCT05004103
- Testing
- Cosmetic products application
- Where
- Indonesia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Fungal Infection, Onychomycosis
An Open-label Study Evaluating the Effectiveness of CGB-400 Topical Gel for Fungal Infection
The goal of the current study is to evaluate the ability of CGB-400, a proprietary eutectic mixture of GRAS compounds, to clear the toenail fungal growth and improve the appearance of the fungus affected area(s).
- Conditions
- Fungal Infection, Onychomycosis, Tinea Unguium
- Trial name
- NCT05202366
- Testing
- CGB-400 Topical Gel
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- CAGE Bio Inc.
Acne
Assessment of a Cosmetic Product Effect on the Host/Microorganism Relationship in Acneic Subjects
The aim of the study is to understand the structural and functional modifications of the host, the microorganisms, and their interactions (host/microorganism relationship) before and after the RV3278A - ET0943 product application
- Trial name
- NCT05640388
- Testing
- RV3278A - ET0943 cosmetic product, RV4632A - RY1845 cosmetic product
- Where
- 2 sites in France
- Volunteers
- 41 people
- Sponsor
- Pierre Fabre Dermo Cosmetique
Healthy Subjects
Dermatological Safety and Skin Compatibility Evaluation of Test Products
Dermatological Safety and Skin Compatibility Evaluation of Test Product following Cosmetics Europe: Product Test Guidelines for Assessment of Human Skin Compatibility (Colipa Standard, 1997)
- Trial name
- NCT07195851
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Skin Aging, Dry Skin
Human In Use Test of GINPI-HP-004 in Healthy Adults
The main objective of this study was to confirm skin acceptability of the product GINPI REF. GINPI BATCH: 10/06/2024 applied under normal use conditions in healthy female adult volunteers, under gynecological control, by means of…
- Trial name
- NCT07533474
- Testing
- Depigmentig cosmetic product
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- i+Med S.Coop.