Clinical trials: Cosmetic Outcome
Breast Cancer
RAPID: Randomized Trial of Accelerated Partial Breast Irradiation
To determine if Accelerated Partial Breast Irradiation, using 3D CRT, is as effective as Whole Breast Irradiation following breast conserving surgery in women with an new histological diagnosis of ductal carcinoma in situ only or…
- Trial name
- NCT00282035
- Testing
- APBI utilizing 3D-CRT radiation, Whole breast irradiation
- Where
- 33 sites in Australia, Canada and 1 more
- Volunteers
- 2,135 people
- Sponsor
- Ontario Clinical Oncology Group (OCOG)
Breast Cancer
Single-dose Preoperative Partial Breast Irradiation in Low-risk Breast Cancer Patients
In this ABLATIVE-2 trial, low-risk breast cancer patients will be treated with MRI-guided single dose preoperative partial breast radiotherapy to assess the rate of pathologic complete response after an interval of six to twelve…
- Trial name
- ABLATIVE-2 (NCT05350722)
- Testing
- Single dose ablative radiotherapy
- Where
- 7 sites in Australia, Netherlands
- Volunteers
- 100 people
- Sponsor
- Amsterdam UMC, location VUmc
Breast Fibrosis, Breast Cancer
An Integrated Optimization of Surgery and Radiotherapy Techniques to Improve Cosmetic Outcome and Quality of Life in Breast Conserving Therapy for Breast Cancer Patients (STARLINGS Study)
To assess the role of different combinations of (oncoplastic) surgery and radiotherapy techniques as risk factors for moderate to severe fibrosis and for moderate to poor cosmetic outcome.
- Conditions
- Breast Fibrosis, Breast Cancer, Breast Cancer Female, Breast Neoplasms
- Trial name
- STARLINGS (NCT05263362)
- Testing
- no intervention
- Where
- 4 sites in Netherlands
- Volunteers
- 775 people
- Sponsor
- Erasmus Medical Center
Eyelid Laceration
Cosmetic Outcome Study of Lid Laceration Repair With Suture Versus Tissue Adhesive
This project is a randomized, controlled trial investigating wound cosmetic appearance after repair of traumatic lid lacerations with three different approaches to skin closure: absorbable sutures, non-absorbable sutures, and…
- Trial name
- NCT01918059
- Testing
- Tissue Adhesive skin closure, Absorbable suture skin closure, Non-absorbable suture skin closure
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- The University of Texas Health Science Center, Houston
Breast Neoplasms
The Oncological Safety and Cosmetic Outcome of Areola Sparing Mastectomy : a Single Arm, Prospective, Cohort Study
To balance the oncological safety and cosmetic outcome is the basic principle of modern breast surgery. To preserve the nipple-areolar complex shows attractive cosmetic advantage but concerns regarding local recurrence make the…
- Trial name
- NCT03105570
- Testing
- Areola Sparing Mastectomy
- Where
- China
- Volunteers
- 145 people
- Sponsor
- Peking University People's Hospital
Cosmetic Outcome, Infection
Sutures Versus Glue in Laparoscopic Port Site Closure.
Cosmesis postoperatively is an important consideration for both patients and surgeons and consequently surgeons have become increasingly interested in replacing conventional sutures by means of adhesive bonds for the closure of…
- Conditions
- Cosmetic Outcome, Infection, Cost
- Trial name
- STILS (NCT03843866)
- Testing
- 4-0 Monocryl, Adhesive Glue
- Where
- Ireland
- Volunteers
- 200 people
- Sponsor
- St. James's Hospital, Ireland
Breast Cancer
Patient Registry: Partial Breast Irradiation
This is an Aurora Health Care system registry of patients receiving accelerated partial breast irradiation and external beam.
- Trial name
- PBI Registry (NCT01127971)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Wake Forest University Health Sciences
Breast Cancer
Proton Accelerated Partial Breast Irradiation
This prospective, non-randomized phase II study will evaluate the cosmetic outcome of using pencil beam scanning proton therapy for partial breast irradiation in patients diagnosed with early stage breast cancer.
- Trial name
- APBI (NCT03940248)
- Testing
- Proton Accelerated Partial Breast Irradiation
- Where
- United States
- Sponsor
- University of Cincinnati
Suture Dermatologic, Surgery
Comparison of Cosmetic Outcomes of Straight Line and W-plasty Techniques for Linear Wound Closure
The purpose of this study is to compare the cosmetic outcome of traditional straight-line (SL) linear closure to that of W plasty (a type of geometric broken-line cutaneous closure technique) for closure of post-auricular wounds…
- Conditions
- Suture Dermatologic, Surgery, Cosmetic Outcome
- Trial name
- NCT05074199
- Testing
- W-plasty/Linear closure
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis
Seroma
The QUILT Study: Quilting Sutures in Patients Undergoing Breast Cancer Surgery
Seroma is the most common complication following breast cancer surgery, with reported incidence up to 90%. Seroma causes patient discomfort, is associated with surgical site infections (SSI), often requires treatment and…
- Trial name
- QUILT (NCT05272904)
- Testing
- Quilting, Conventional wound closure
- Where
- Netherlands
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Canisius-Wilhelmina Hospital
Breast Cancer Female
Cosmetic Outcome, Patient-reported Outcomes, and Reconstruction-related Complications in Breast Cancer Women Treated With or Without Post-mastectomy Radiation Therapy
This study aim to investigate the breast reconstruction outcome after mastectomy with or without radiation therapy from the patient's point of view.
- Trial name
- NCT03523078
- Testing
- Breast reconstructive surgery
- Where
- South Korea
- Volunteers
- 500 people
- Sponsor
- Yonsei University
Surgery
Thyroid Cosmesis Study at St. Paul's Hospital, Vancouver BC
This study looks at the difference in surgical scar outcomes between two different surgical incision methods during thyroid surgery: scalpel vs electrocautery. Patients who are already scheduled for thyroid surgery with Dr.
- Trial name
- NCT02458989
- Testing
- Scalpel, Electrocautery
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr. Sam M. Wiseman
Burns
A Randomized Comparison Study of Aquacel Ag and Glucan II as Donor Site Dressings
The research will be looking at patient outcomes for healing of donor sites after a split-thickness skin graft procedure for a burn or skin tissue loss.
- Trial name
- NCT00581217
- Testing
- Aquacel Ag, Glucan II
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, Irvine
Thyroidectomy, Distress
Postoperative Distress and Cosmetic Outcomes After Open Versus Robotic Thyroidectomy
Robotic assistance during thyroid surgery has been utilized clinically in Korea since late 2007. Robotic thyroidectomy has also been validated for surgical management of the thyroid gland.
- Conditions
- Thyroidectomy, Distress, Surgery
- Trial name
- Robot1 (NCT01075269)
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Korean Association of Endocrine Surgeons
Wound Complication, Surgical Wound Infection
Electrocautery Versus Scalpel for Skin Incisions
The aim of this research project is to compare electrocautery to scalpel for laparotomy skin incisions, with the following objectives: 1. To investigate whether electrocautery produces a cosmetically inferior surgical scar. 2.
- Conditions
- Wound Complication, Surgical Wound Infection, Post-operative Pain
- Trial name
- NCT01496404
- Testing
- Electrocautery, Scalpel
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- St. Paul's Hospital, Canada
Breast Neoplasm, Cosmetic Outcome
Aspects of Breast-conserving Surgery
Prospective study of cosmetic outcome and quality of life for women undergoing breast cancer surgery using patient a reported outcome measure (BREAST-Q) and a computer program validated to assess cosmetic outcomes after breast…
- Conditions
- Breast Neoplasm, Cosmetic Outcome, Quality of Life
- Trial name
- NCT04227613
- Where
- Sweden
- Volunteers
- 351 people
- Sponsor
- Lund University
Breast Cancer
Conventional Versus Hypofractionated Radiotherapy in Node Positive Breast Cancer
Breast cancer patients operated with modified radical mastectomy or breast conservative surgery will be randomized for either adjuvant conventional radiotherapy versus hypofractionated radiotherapy for chest wall and axilla or…
- Trial name
- NCT02690636
- Testing
- radiotherapy
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Ain Shams University
Skin Tumour, Surgery
Intracutaneous Versus Transcutaneous Sutures in the Face (IC vs TC Sutures)
Rationale: Skin cancer is common in Caucasians and often exists on sun-exposed areas, such as the face. Treatment of choice is mostly excision and result in an irreversible scar.
- Trial name
- NCT02125058
- Testing
- Transcutaneous sutures, Intracutaneous sutures
- Where
- 3 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Maastricht University Medical Center
Scar Improvement, Cosmetic Outcome
Tape Application Protocol for Enhanced Scars
What is the purpose of this study? The Investigators want to find out whether applying Micropore surgical tape to the medial half of the mastectomy scar for 3 months helps improve its appearance after 12 months, compared to no…
- Trial name
- TAPES (NCT07144046)
- Testing
- Micropore covering of the medial half of the scar
- Volunteers
- 90 people
- Sponsor
- Herlev Hospital
Suture, Dermatologic Surgery
Aesthetic Outcome of Running Cuticular Suture Distance (2mm vs 5mm)
It is standard teaching that the top layer of sutures should be placed 3-5mm from the wound edge. However, there is lack of data regarding the most optimal placement of sutures from the wound edge for the best cosmetic outcome.
- Conditions
- Suture, Dermatologic Surgery, Scar, Cosmetic Outcome
- Trial name
- NCT04870008
- Testing
- Suture
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of California, Davis