Clinical trials: Cortical Spreading Depolarization and Depression
Subarachnoid Hemorrhage, Intracerebral Hemorrhage
Multimodal Neuromonitoring
Theoretical Framework \& Background Cortical spreading depressions (CSD) and seizures, are crucial in the development of delayed cerebral ischemia and poor functional outcome in patients suffering from acute brain injuries such…
- Conditions
- Subarachnoid Hemorrhage, Intracerebral Hemorrhage, Traumatic Brain Injury, Cortical Spreading Depolarization and Depression
- Trial name
- MMNM (NCT04737369)
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Cortical Spreading Depolarization, Cortical Spreading Depression
Spreading Depolarization and Ketamine Suppression
Hypothesis: Cortical spreading depolarizations are inhibited by the NMDA receptor antagonist Ketamine Aim 1: To demonstrate, in a group of patients with acute severe brain injury requiring surgery including traumatic brain injury…
- Conditions
- Cortical Spreading Depolarization, Cortical Spreading Depression, Subarachoid Hemorrhage, Traumatic Brain Injury
- Trial name
- SAKS (NCT02501941)
- Testing
- ketamine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of New Mexico