Clinical trials: Coronary Intervention
Atrial Septal Defect, Patent Foramen Ovale
Canadian Adult Congenital Heart Disease Intervention Registry
The ACHDi Registry study will create a foundational database for adult congenital heart disease interventions. This Pan-Canadian Registry will collect clinical and patient-reported information that will enable the evaluation of…
- Conditions
- Atrial Septal Defect, Patent Foramen Ovale, Tetralogy of Fallot, Fontan
- Trial name
- C-ACHDiR (NCT04288596)
- Testing
- Participants undergoing ACHD intervention
- Where
- Canada
- Volunteers
- 9,000 people
- Sponsor
- University Health Network, Toronto
Myocardial Ischemia, Ischemic Reperfusion Injury
Remote Ischemic Preconditioning in Elective Percutaneous Interventions
Myocardial injury occurs after percutaneous coronary intervention due to micro emboli, ischemia-reperfusion injury or side branch occlusion.
- Trial name
- NCT02581618
- Testing
- remote ischemic preconditioning
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Trakya University
Atrial Fibrillation
The Norwegian Exercise in Atrial Fibrillation Trial
Atrial fibrillation (AF) patients suffer a high symptom burden and reduced quality of life (QoL), high hospitalization rates and few effective treatment options. They have a high burden of cardiovascular risk factors and events.
- Trial name
- NEXAF (NCT05164718)
- Testing
- Supervised home-based exercise, Usual care
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Norwegian University of Science and Technology
Heart Failure
Feasibility of Pharmaceutical Interventions in Elderly Heart Failure Patients.
Heart failure therapies (e.g. beta blockers) have been successful in decreasing mortality rates, as well as diminishing hospitalizations.
- Trial name
- RASP-HF (NCT02149940)
- Testing
- heart-failure related pharmaceutical intervention
- Where
- Belgium
- Volunteers
- 29 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Coronary Artery Disease
Predictive Value of Allen's Test Result in Elective Patients Undergoing Coronary Catheterization Through Radial Approach
The study will evaluate the feasibility and safety of radial approach in patients undergoing coronary catheterisation without any restrictions based on the results of Allen's test.
- Trial name
- RADAR (NCT00597324)
- Testing
- coronary catheterisation
- Where
- Italy
- Volunteers
- 203 people
- Sponsor
- Marco Valgimigli
Coronary Artery Disease, Acute Coronary Syndrome
BIOSTEMI Extended Survival
The objective of the BIOSTEMI ES study is to assess the long-term clinical outcomes with the Orsiro ultrathin-strut biodegradable polymer sirolimus-eluting stent compared to the Xience thin-strut durable polymer…
- Trial name
- BIOSTEMI ES (NCT05484310)
- Where
- 10 sites in Switzerland
- Volunteers
- 1,300 people
- Sponsor
- University Hospital, Geneva
Heart Disease
Diet and Active Lifestyle - Yuuyaraq (The Yup'ik Way of Life)
Heart disease is the leading cause of death for Alaska Native men and the second leading cause of death (after cancer) among women and Alaska Native people overall.
- Trial name
- DAiLY (NCT06629610)
- Testing
- DAiLY
- Where
- 2 sites in United States
- Volunteers
- 368 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Ischemic Heart Disease, Nerve Injury
Association Between Radial Artery Intervention and Development of Neuropathy in the Hand - A Prospective Study
Evaluation of potential nerve damage after radial CAG/PCI.
- Conditions
- Ischemic Heart Disease, Nerve Injury, Carpal Tunnel Syndrome
- Trial name
- ACCESS-IV (NCT05365282)
- Where
- Denmark
- Volunteers
- 400 people
- Sponsor
- Aarhus University Hospital Skejby
Coronary Artery Disease, Angina Pectoris
Patient-Reported Preferences Affecting Revascularization Decisions
Selection of a treatment strategy for patients with symptoms due to coronary artery disease requires consideration of patient preferences.
- Trial name
- PREPARED (NCT02272062)
- Testing
- Decision-making tool for coronary artery disease treatment
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Duke University
Physical Activity, Coronary Artery Disease
Prognostic Impact of Physical Activity Patterns After Percutaneous Coronary Intervention (PIPAP Study)
Physical activity monitoring after coronary bypass grafting and other major surgeries has been found to be predictive for hospital readmission and adverse outcome.
- Trial name
- PIPAP (NCT04663373)
- Testing
- Step counting
- Where
- Switzerland
- Volunteers
- 568 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Disease
Multi-Center Clinical Trial: Evaluation of Effectiveness and Safety
This trial aims to demonstrate the non-inferiority of the CI-CMS-005 Coronary Stent System to the study device as well as to the TAXUS™ Express2™ Drug-Eluting Coronary Stent System in in-segment late lumen loss at 9 months after…
- Trial name
- NCT00415961
- Testing
- CoStar Paclitaxel Drug-Eluting Coronary Stent System
- Where
- Japan
- Volunteers
- 120 people
- Sponsor
- Conor Medsystems
Coronary Disease
Cobalt Chromium Stent With Antiproliferative for Restenosis II Trial (COSTAR II)
The purpose of this study is to evaluate the safety and effectiveness of the investigational stent CoStar™ Paclitaxel-Eluting Coronary Stent- a reservoir based DES system in comparison to a surface coated DES stent (TAXUS™…
- Trial name
- NCT00165035
- Testing
- CoStar Paclitaxel Drug Eluting Coronary Stent System, TAXUS™ Express2™ Paclitaxel-Eluting Coronary Stent
- Where
- 2 sites in United States
- Volunteers
- 1,701 people
- Sponsor
- Cordis US Corp.
Diabetes Mellitus Type II, Acute Coronary Syndrome
VERifynow in DIabetes Non-responsiveness: a Study on Switching From Clopidogrel to Prasugrel
The purpose of this study is to determine if, in type 2 diabetic patients undergoing treatment with PCI and a stent, who fail to respond to normal doses of clopidogrel, a loading dose of 60 mg of prasugrel followed by 10 mg once…
- Trial name
- VERDI (NCT01684813)
- Testing
- Prasugrel., Clopidogrel
- Where
- Spain
- Volunteers
- 65 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Coronary Artery Disease, Acute Coronary Syndrome
PRESSUREwire Study
The purpose of this study is to understand routine use of FFR (Fractional Flow Reserve) and alternate indices in clinical practice.
- Trial name
- NCT02935088
- Testing
- Fractional Flow Reserve
- Where
- 71 sites in United States, Austria and 13 more
- Volunteers
- 2,217 people
- Sponsor
- Abbott Medical Devices
Myocardial Infarction
Randomized Evaluation of Shenfu Injection to Reduce Myocardial Injury
This study aims to evaluate whether perioperative use of Shenfu Injection, as compared to placebo, could reduce infarct size assessed by cardiac magnetic resonance (CMR) in patients with acute anterior ST-segment elevation…
- Trial name
- RESTORE (NCT04493840)
- Testing
- Shenfu Injection, 5% Glucose Injection
- Where
- China
- Volunteers
- 326 people
- Sponsor
- Beijing Anzhen Hospital
Coronary Disease
Pro-calcitonin Marker as Indicator of Ischemia in Patients With Complicated Coronary Intervention.
The aim of this study is to determine on preliminary basis weather an elevated pro-calcitonin level can be used to assess ischemia as a result of coronary artery complications during percutaneous coronary intervention (PCI).
- Trial name
- NCT01609569
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Saint Michael's Medical Center
Chronic Total Occlusion of Coronary Artery
CT Coronary Angiography Prior to CTO PCI
A Chronic Total Occlusion or CTO of a coronary artery is a an artery that has been blocked for >/= 3 months. More than a decade ago, patients with such coronary artery blockage would have been sent for Coronary Artery Bypass…
- Trial name
- NCT05364827
- Testing
- CTCA
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sandwell & West Birmingham Hospitals NHS Trust
Atrial Fibrillation (AF), Atrial Flutter
Registry of Atrial Arrhythmia Ablation Procedures Using Pulsed Field Ablation in Poland
The aim of the described project is to establish a multicenter, nationwide registry of atrial arrhythmia ablation procedures using the Pulsed Field Ablation (PFA) method.
- Conditions
- Atrial Fibrillation (AF), Atrial Flutter, Atrial Tachycardia, Ablation Techniques
- Trial name
- PFA Registry (NCT07109141)
- Testing
- PFA ablation procedure of atrial arrythmia
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Wroclaw Medical University
Atrial Fibrillation, Valve
The Concomitant Cryomaze Procedure Using Nitreous Oxide Cryoprobe: Comparison With Argon Based Cryoprobe
The aim of this study is compare the surgical convenience and early and long-term outcomes of cryomaze procedure using nitrous oxide with using Argon gas.
- Trial name
- NCT01812356
- Testing
- Cryomaze procedure using Nitrous oxide, Cryomaze procedure using Argon
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Samsung Medical Center
Obesity, Cardiovascular Disease
Healthy Bodies, Healthy Hearts: A Physical Activity Intervention Trial
The overall aim of Healthy Bodies, Healthy Hearts research study is to promote physical activity in women aged 45-65 years to promote reduced risk of cardiovascular disease.
- Conditions
- Obesity, Cardiovascular Disease, High Blood Pressure
- Trial name
- HBHH (NCT01099007)
- Testing
- In Person, At Home
- Where
- United States
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh