Clinical trials: Coronary Heart Disease NOS
Congenital Heart Defects, Hypoplastic Left Heart Syndrome
Cerebral Perfusion During Neonatal Cardiac Surgery
Neonates with a congenital heart defect are often in need of early cardiac surgery. In complex congenital heart defects, cardiopulmonary bypass is usually employed, with or without deep hypothermic circulatory arrest (DHCA).
- Conditions
- Congenital Heart Defects, Hypoplastic Left Heart Syndrome, Aortic Coarctation
- Trial name
- NCT01032876
- Testing
- Deep Hypothermic Circulatory Arrest, Antegrade Cerebral Perfusion
- Where
- Netherlands
- Volunteers
- 37 people
- Sponsor
- UMC Utrecht
Coronary Heart Disease, Acute Myocardial Infarction
Twenty-year Follow-up of the Inter99 Cohort
Being born small increases your risk of developing Type 2 diabetes (T2D) with age. Furthermore, data even suggest that some of the diseases ("complications") in the eyes, kidneys, nerves, liver, blood vessels and heart often seen…
- Conditions
- Coronary Heart Disease, Acute Myocardial Infarction, Cardiovascular Diseases, Type 2 Diabetes
- Trial name
- NCT05166447
- Where
- Denmark
- Volunteers
- 4,000 people
- Sponsor
- Bispebjerg Hospital
Arrhythmias, Cardiac, Children, Only
Mobile Electrocardiogram Monitoring for Detecting Arrhythmias in Children
The objective of this project is to evaluate the capability of a specific mobile electrocardiogram monitoring of detecting arrhythmic events in children with history of palpitation and or syncope.
- Conditions
- Arrhythmias, Cardiac, Children, Only, Congenital Heart Disease, Sudden Cardiac Death
- Trial name
- NCT05140343
- Testing
- KARDIA Mobile ECG Monitoring (KMCM)
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Centro Medico Teknon
Congenital Heart Disease, Behavior, Health
Improving Congenital Heart Disease Care
The theory-informed digital health intervention, called as "Empower My Congenital Health (EmpowerMyCH)" aims to activate and engage ACHD patients in building confidence toward navigating the adult healthcare system.
- Conditions
- Congenital Heart Disease, Behavior, Health, Quality of Life, Empowerment, Patient
- Trial name
- EmpowerMyCH (NCT06581484)
- Testing
- Digital patient empowerment intervention
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of California, San Francisco
Nonfatal Myocardial Infarction, Coronary Death
Association Between Low Dose Acetylsalicylic Acid (ASA) and Proton Pump Inhibitors and Risk of Acute Myocardial Infarction or Coronary Death
The purpose of this study is to estimate the risk of myocardial infarction (MI)/coronary death associated with use of monotherapy low dose ASA (single antiplatelet) as well as concomitant use of monotherapy low dose ASA and…
- Trial name
- NCT01360047
- Where
- Spain
- Volunteers
- 39,513 people
- Sponsor
- AstraZeneca
Coronary Heart Disease, Angina Pectoris
The Effects of Diesel Exhaust Inhalation On Exercise Capacity In Patients With Stable Angina Pectoris
The purpose of this study is to determine whether exposure to diesel exhaust (air pollution) has a functional impact on patients with stable angina pectoris.
- Trial name
- NCT00737958
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- University of Edinburgh
Myocardial Infarction, ST Elevation Myocardial Infarction
10-Years Follow-up of the EXAMINATION Trial
The EXAMINATION trial was a superiority trial that compared everolimus-eluting stents (EES) versus bare-metal stents (BMS) in an all-comer ST-segment elevation myocardial infarction (STEMI) population.
- Conditions
- Myocardial Infarction, ST Elevation Myocardial Infarction, Infarction, Necrosis
- Trial name
- EXAMINAT10N (NCT04462315)
- Testing
- Everolimus Eluting Coronary Stent System, Cobalt chromium balloon expandable stent (non-drug-eluting stent Arm)
- Where
- 11 sites in Italy, Netherlands and 1 more
- Volunteers
- 1,498 people
- Sponsor
- Hospital Clinic of Barcelona
Obesity & Overweight, Coronary Heart Disease
Effect of Mazdutide on Coronary Plaque in Patients With Coronary Atherosclerosis and Overweight or Obesity
This multicenter, randomized, double-blind, placebo-controlled trial aims to evaluate the effect of mazdutide, a dual GLP-1/GCG receptor agonist, on coronary plaque progression assessed by coronary computed tomography angiography…
- Trial name
- NCT07657676
- Testing
- Mazdutide
- Where
- China
- Volunteers
- 116 people
- Sponsor
- China National Center for Cardiovascular Diseases
Hematologic Diseases
Hematological Abnormalities in Children
the aim of the study is to determine Hematological abnormalities in Congenital Cyanotic Heart Disease
- Trial name
- NCT05541835
- Testing
- sampling
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Coronary Heart Disease (CHD)
Metoprolol and Trimetazidine for Coronary Heart Disease With Angina
This is a prospective, randomized study to evaluate the effectiveness and safety of combining metoprolol succinate with trimetazidine compared to standard therapy for patients with coronary heart disease (CHD) and angina…
- Trial name
- NCT07074834
- Testing
- Metoprolol Succinate Sustained-Release Tablets, Trimetazidine, Routine Drug Therapy
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Shiyan City Renmin Hospital
Coronary Heart Disease, Atherosclerosis
Fluvastatin AmelIorates aTHerosclerosis Study
The study is designed to assess the effect of statin on atherosclesrosis progression as well as to explore its potential mechanism besides lipid modifying , such as effect on inflammation and vascular calcification.
- Trial name
- FAITH (NCT01681199)
- Testing
- Fluvastatin extended release tablet
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Beijing Anzhen Hospital
Carcinoid Heart Disease, Neuroendocrine Tumors
CardioNETPOL National Registry of Carcinoid Heart Disease
Carcinoid tumors are neuroendocrine tumors (NETs), most commonly originating from the gastrointestinal tract, that may secrete bioactive substances such as serotonin.
- Conditions
- Carcinoid Heart Disease, Neuroendocrine Tumors, Carcinoid Syndrome, Valvular Heart Disease Patients
- Trial name
- CardioNETPOL (NCT07450287)
- Testing
- Observational Registry of Carcinoid Heart Disease
- Where
- Poland
- Volunteers
- 120 people
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
Anemia, Diabetes
A Comparative Clinical Trial of the TensorTip, a Novel Non Invasive Device for Measurement Blood Parameters
1. Aim: The aim of the clinical trial is to study the accuracy of the TensorTip device compared with registered (FDA-approved) invasive and non-invasive devices. 2.
- Conditions
- Anemia, Diabetes, Heart Disease, High Blood Pressure
- Trial name
- NCT01196533
- Testing
- Non invasive peripheral blood monitoring
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Cnoga Medical Ltd.
Growth Failure, Congenital Heart Disease
A Study to Evaluate the Effects of a New Formula on the Growth, Safety and Tolerance of Infants With Growth Failure
This study is a prospective, open-label, multi-site, growth, safety and tolerance study to evaluate a NF (New Formula). A minimum of 45 evaluable infants with confirmed growth failure will be enrolled.
- Trial name
- NCT03563391
- Testing
- New Infant Formula
- Where
- 5 sites in United States
- Volunteers
- 30 people
- Sponsor
- Nutricia North America
Elderly Patients (>65 Years), Diabetes (DM)
Multidisciplinary Dissection of Renal and Metabolic Effects of Glyfozines on Elderly Patients: From Molecular Aspects to Clinical Indications
The project aims to study the impact of SGLT2i therapy on clinical and biochemical aspects. in elderly. The project will combine different types of data, such as clinical and biological information, and will use advanced Bayesian…
- Conditions
- Elderly Patients (>65 Years), Diabetes (DM), Heart Disease, Renal Diseases
- Trial name
- NCT07119424
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Chiara Lanzani
CHD - Congenital Heart Disease
Home-based Cardiovascular Rehabilitation in Young Patients With Congenital Heart Disease: the "Muscle Your Heart" Program
Standard cardiovascular rehabilitation is performed in a medical care and rehabilitation centre. However, it may not be adapted to the patient's profile and there are few medical care and rehabilitation centres specialized in…
- Trial name
- Muscletoncoeur (NCT07115589)
- Testing
- Muscle Your Heart home-based program
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
Congenital Heart Disease
Health Literacy in Adults With Congenital Heart Disease
Currently, both oral and written health education make certain assumptions about the health literacy of patients and their parents.
- Trial name
- NCT03170024
- Where
- United States
- Volunteers
- 187 people
- Sponsor
- Stanford University
Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction
Feasibility of Non-invasive Hemodynamic Assessment by 5D Flow in Congenital Heart Disease
This study evaluates whether new flow parameters of the cardiac magnetic resonance imaging (MRI) allow evaluation of parameters for which usually invasive rigth-left heart catheterization are necessary.
- Conditions
- Pulmonary Hypertension, Right Ventricular Outflow Tract Dysfunction, Fontan Circulation
- Trial name
- NCT07742046
- Testing
- Right-left heart catheterization in magnetic resonance imaging (MRI)
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Tobias Rutz
Patient Undergoing CABG Surgery, Ischemic Heart Disease Patients
Arterial to Central co2gap in Relation to Outcome After Cardiopulmonary Bypass
This trial aims to study the performance of CO2 gap, lactate level, and central venous oxygen saturation in predicting major postoperative complications after cardiac surgery with cardiopulmonary bypass
- Trial name
- NCT06839027
- Where
- Egypt
- Volunteers
- 130 people
- Sponsor
- Ain Shams University
Premature Coronary Heart Disease
Multi-modal Adverse Events Prediction for Premature Coronary Heart Disease Trial: MAP-CHD Trial
The goal of this observational cohort study is to establish a risk prediction model for adverse events in Chinese individuals under 45 years old with premature coronary artery disease.
- Trial name
- NCT07004452
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- China National Center for Cardiovascular Diseases