Clinical trials: Coronary Artery Disease(CAD)
Coronary Artery Disease
The Arterial Revascularization Therapies Study Part II.
The main objective is to compare the effectiveness of coronary stent implantation using the sirolimus-eluting Bx VELOCITY™ balloon expandable stent with that of surgery as observed in ARTS I.
- Trial name
- ARTS II (NCT00235170)
- Testing
- drug-eluting stent
- Where
- Netherlands
- Volunteers
- 607 people
- Sponsor
- Cordis US Corp.
Myocardial Ischemia, Ischemic Reperfusion Injury
Remote Ischemic Preconditioning in Elective Percutaneous Interventions
Myocardial injury occurs after percutaneous coronary intervention due to micro emboli, ischemia-reperfusion injury or side branch occlusion.
- Trial name
- NCT02581618
- Testing
- remote ischemic preconditioning
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Trakya University
Coronary Artery Disease
Evaluation of Health Economics for Noninvasive Coronary Fractional Flow Reserve Measurement Technology
To determine whether, in a Chinese population of patients presenting to Wuhan Asia Heart Hospital, Fractional Flow Reserve Derived from Coronary Computed Tomography Angiography (CT-FFR) as a default test is noninferior in terms…
- Trial name
- NCT05593120
- Testing
- CT-FFR, Routine care
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shenzhen Raysight Intelligent Medical Technology Co., Ltd.
Cardiovascular Diseases
Time-trend Analysis of Clinical Characteristic and Outcomes in Patients With Unprotected Left Main Coronary Artery Disease Treated With PCI Over a 10-year Period
Surgical coronary bypass surgery (CABG) has been demonstrated to confer significant survival benefit over medical therapies patients with LMCA in earlier clinical trials1,2,3 and therefore was the revascularization modality of…
- Trial name
- NCT05548023
- Testing
- The AngioliteTM Durable Fluoroacrylate Polymer-based Sirolimus-Eluting Stent
- Where
- Hong Kong
- Volunteers
- 500 people
- Sponsor
- Chinese University of Hong Kong
Coronary Artery Disease
Relation Between Lymphocyte-to-C-Reactive Protein Ratio and Coronary Artery Disease Complexity
Aim(s) of the Research : 1. To assess the relationship between the lymphocyte-to-CRP ratio and CAD complexity as assessed by Syntax score in both emergency (STEMI patients undergoing PPCI) and elective settings (patients…
- Trial name
- NCT06958562
- Testing
- No intervention administered. Standard care will be provided. Blood samples for lymphocyte count and CRP will be collected, and Syntax score will be calculated from angiography.
- Volunteers
- 600 people
- Sponsor
- Assiut University
Coronary Disease
Prospective Evaluation of MyocaRdial PerFUSion ComputEd Tomography Trial
The purpose of this study is to evaluate safety and effectiveness of CTP(computed tomography perfusion) guided revascularization vs FFR(Fractional flow reserve) guided revascularization
- Trial name
- PERFUSERCT (NCT02208388)
- Testing
- computed tomography perfusion guided treatment, Fractional flow reserve guided treatment
- Where
- 7 sites in South Korea
- Volunteers
- 1,000 people
- Sponsor
- Young-Hak Kim, MD, PhD
Cardiovascular Diseases, Coronary Disease
Determinants of Coronary Disease in High Risk Families
To define factors contributing to coronary heart disease (CHD) in high risk families.
- Conditions
- Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00005508
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Safety and Effectiveness of Visipaque 320mg-I/ml for Use in Contrast-Enhanced CT Angiography of Arteries of the Heart
CT (computed tomography) angiography (CTA) is an examination similar to a CAT scan that uses x-rays and a contrast medium (also called dye) to visualize blood flow in arteries and veins throughout the body.
- Trial name
- NCT00335335
- Testing
- iodixanol
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- GE Healthcare
Coronary Artery Disease, Endothelial Function
Differential Effect of Ticagrelor Versus Prasugrel Maintenance Dose on Endothelial Function of Peripheral Vessels in Patients With Coronary Artery Disease
Ticagrelor administration, whose molecule resembles to adenosine, led to reduction in overall mortality and thrombotic cardiovascular (CV) events when directly compared to clopidogrel in the PLATO trial, implicating possible…
- Trial name
- NCT01957540
- Testing
- Ticagrelor, Prasugrel
- Where
- Greece
- Volunteers
- 22 people
- Sponsor
- University of Patras
Cardiovascular Diseases, Heart Diseases
Epidemiology of Cardiovascular and Non-Cardiovascular Risk In Chicago
To continue the comprehensive research program on the epidemiology of cardiovascular and other major chronic diseases, including cancer and diabetes, in four Chicago population cohorts.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Cerebrovascular Disorders
- Trial name
- NCT00005140
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
A Trial of Firesorb in Patients With Coronary Artery Disease: FUTURE-II
The FUTURE-II study is a confirmative clinical trial for Sirolimus Target Eluting Bioresorbable Vascular Scaffold (Firesorb) after the feasibility and safety of the device has been preliminary confirmed in a small-scale…
- Trial name
- FUTURE-II (NCT02890160)
- Testing
- Firesorb, XIENCE
- Where
- China
- Volunteers
- 430 people
- Sponsor
- Shanghai MicroPort Medical (Group) Co., Ltd.
Coronary Artery Disease
Predictive Value of Allen's Test Result in Elective Patients Undergoing Coronary Catheterization Through Radial Approach
The study will evaluate the feasibility and safety of radial approach in patients undergoing coronary catheterisation without any restrictions based on the results of Allen's test.
- Trial name
- RADAR (NCT00597324)
- Testing
- coronary catheterisation
- Where
- Italy
- Volunteers
- 203 people
- Sponsor
- Marco Valgimigli
Coronary Artery Disease, Acute Coronary Syndrome
BIOSTEMI Extended Survival
The objective of the BIOSTEMI ES study is to assess the long-term clinical outcomes with the Orsiro ultrathin-strut biodegradable polymer sirolimus-eluting stent compared to the Xience thin-strut durable polymer…
- Trial name
- BIOSTEMI ES (NCT05484310)
- Where
- 10 sites in Switzerland
- Volunteers
- 1,300 people
- Sponsor
- University Hospital, Geneva
Coronary Artery Disease, Angina Pectoris
Patient-Reported Preferences Affecting Revascularization Decisions
Selection of a treatment strategy for patients with symptoms due to coronary artery disease requires consideration of patient preferences.
- Trial name
- PREPARED (NCT02272062)
- Testing
- Decision-making tool for coronary artery disease treatment
- Where
- United States
- Volunteers
- 203 people
- Sponsor
- Duke University
Acute Coronary Syndrome, Angina Pectoris
Comparison of BIOdegradable Polymer and DuRablE Polymer Drug-eluting Stents in an All COmeRs PopulaTion (BIO-RESORT)
The introduction of drug-eluting stents (DES) in the treatment of coronary artery disease has led to a significant reduction in morbidity.
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, Angina, Unstable, Myocardial Infarction
- Trial name
- BIO-RESORT (NCT01674803)
- Testing
- Orsiro, Synergy, Resolute Integrity
- Where
- Netherlands
- Volunteers
- 3,514 people
- Sponsor
- Foundation of Cardiovascular Research and Education Enschede
Physical Activity, Coronary Artery Disease
Prognostic Impact of Physical Activity Patterns After Percutaneous Coronary Intervention (PIPAP Study)
Physical activity monitoring after coronary bypass grafting and other major surgeries has been found to be predictive for hospital readmission and adverse outcome.
- Trial name
- PIPAP (NCT04663373)
- Testing
- Step counting
- Where
- Switzerland
- Volunteers
- 568 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Primary Prevention of Atherosclerotic Cardiovascular Disease
A Study of Inclisiran to Prevent Cardiovascular Events in High-risk Primary Prevention Patients.
CKJX839D12302 is a pivotal Phase III study designed to test the hypothesis that treatment with inclisiran sodium 300 milligram (mg) subcutaneous (s.c.) administered on Day 1, Day 90, and every 6 months thereafter in patients at…
- Trial name
- NCT05739383
- Testing
- Inclisiran sodium 300 mg (equivalent to 284 mg inclisiran) in 1.5 mL
- Where
- 983 sites in United States, Argentina and 40 more
- Volunteers
- 14,012 people
- Sponsor
- Novartis Pharmaceuticals
Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction
Coronary Microvascular Dysfunction in Angina Patients With Non-obstructive Coronary Artery Disease (ANOCA-CMD)
The goal of this observational study is to explore the incidence and effect on prognosis of coronary microvascular dysfunction in patients present of stable anginal symptoms, a clinical indication for invasive coronary…
- Conditions
- Angina Patients With Non-obstructive Coronary Artery Disease, Coronary Microvascular Dysfunction, Index of Microvascular Resistance
- Trial name
- NCT06503640
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital
Coronary Disease
Multi-Center Clinical Trial: Evaluation of Effectiveness and Safety
This trial aims to demonstrate the non-inferiority of the CI-CMS-005 Coronary Stent System to the study device as well as to the TAXUS™ Express2™ Drug-Eluting Coronary Stent System in in-segment late lumen loss at 9 months after…
- Trial name
- NCT00415961
- Testing
- CoStar Paclitaxel Drug-Eluting Coronary Stent System
- Where
- Japan
- Volunteers
- 120 people
- Sponsor
- Conor Medsystems
Coronary Disease
Cobalt Chromium Stent With Antiproliferative for Restenosis II Trial (COSTAR II)
The purpose of this study is to evaluate the safety and effectiveness of the investigational stent CoStar™ Paclitaxel-Eluting Coronary Stent- a reservoir based DES system in comparison to a surface coated DES stent (TAXUS™…
- Trial name
- NCT00165035
- Testing
- CoStar Paclitaxel Drug Eluting Coronary Stent System, TAXUS™ Express2™ Paclitaxel-Eluting Coronary Stent
- Where
- 2 sites in United States
- Volunteers
- 1,701 people
- Sponsor
- Cordis US Corp.
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.