Clinical trials: Coronary Artery Bypass Grafting, open to volunteers
Coronary Artery Bypass Grafting (CABG) Surgery, Coronary Artery Disease
Prospective Study Protocol for Multiparametric PCCT Assessment of Early Ventricular Outcomes After CABG
The goal of this observational study is to learn whether information about heart muscle tissue from preoperative photon-counting CT, a newer type of CT scan, can help predict heart recovery 3 months after coronary artery bypass…
- Trial name
- PCCT-CABG (NCT07883499)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Xin Lou
Coronary Artery Disease, Coronary Artery Bypass Grafting
TOP-CABG Trial: Follow-up Extension (TOP-CABG FE)
To further evaluate the long-term effects of the two antiplatelet strategies on saphenous vein graft patency, long-term adverse cardiovascular events, and bleeding events after coronary artery bypass grafting (CABG), we plan to…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Dual Antiplatelet Therapy, Bleeding
- Trial name
- NCT07871591
- Volunteers
- 2,290 people
- Sponsor
- China National Center for Cardiovascular Diseases
Coronary Artery Bypass Grafting, Postoperative Recovery
Artificial Intelligence-Supported Individualized Discharge Education After Coronary Artery Bypass Grafting
This randomized controlled trial aims to evaluate the effect of artificial intelligence-supported individualized discharge education on postoperative recovery in patients undergoing coronary artery bypass grafting.
- Trial name
- NCT07780994
- Testing
- Artificial Intelligence-Supported Individualized Discharge Education, Standard Discharge Education
- Volunteers
- 80 people
- Sponsor
- Izmir Katip Celebi University
Coronary Artery Disease, Coronary Artery Bypass Grafting
CCTA-Based vs CAG-Based CABG: A Multicenter Pragmatic Non-Inferiority Trial
The goal of this clinical trial is to find out if using a non-invasive heart scan (called coronary computed tomography angiography, or CCTA) to plan coronary artery bypass grafting (CABG) works as well as the standard invasive…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Coronary Computed Tomography Angiography, Coronary Angiography (CAG)
- Trial name
- CtaCAB (NCT07769008)
- Testing
- CCTA-based CABG, CAG-based CABG
- Where
- China
- Volunteers
- 826 people
- Sponsor
- Ruijin Hospital
Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery
ESPB vs SPSIP for Postoperative Analgesia After CABG
This prospective, randomized, active-controlled, double-blind, parallel-group study compares the postoperative analgesic efficacy and safety of ultrasound-guided bilateral Erector Spinae Plane Block (ESPB) versus bilateral…
- Conditions
- Coronary Arterial Disease, Coronary Artery Bypass Grafting (CABG) Surgery, Postoperative Pain Management
- Trial name
- ESP-SPSIP-CABG (NCT07388745)
- Testing
- Ultrasound-guided Erector Spinae Plane Block (ESPB), Ultrasound-guided Serratus Posterior Superior Intercostal Plane Block (SPSIPB)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Kutahya Health Sciences University
Coronary Heart Disease, Coronary Artery Bypass Grafting
Thiamine Intervention and Coronary Artery Bypass Grafting
The purpose of this study is to gain a better understanding of the association between brain changes and cognitive deficits in coronary heart disease (CHD) patients undergoing coronary artery bypass grafting (CABG) and whether a…
- Trial name
- B1&CABG (NCT06326996)
- Testing
- Thiamine
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of California, Los Angeles
Coronary Artery Bypass Grafting (CABG) Surgery, Saphenectomy
Adductor Canal Block: Efficacy in Postoperative Pain Management for Cardiac Surgery
Adductor Canal Block: Efficacy in Postoperative Pain Management for Cardiac Surgery
- Trial name
- AddEase (NCT07732465)
- Testing
- Aductor canal bloc, Control adductor canal block
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Montreal Heart Institute
Coronary Artery Bypass Grafting (CABG) Surgery, Heart Valve Surgery
From Prehabilitation to Rehabilitation (Prehab2Rehab): Digitally Supported Short-Term Prehabilitation Prior to Cardiac Surgery
Prehab2Rehab is a prospective single-arm feasibility study evaluating the implementation of a multimodal, digitally supported prehabilitation program for adults awaiting elective cardiac surgery.
- Conditions
- Coronary Artery Bypass Grafting (CABG) Surgery, Heart Valve Surgery, Surgical Closure of an Atrial Septal Defect (ASD)
- Trial name
- Prehab2Rehab (NCT07716761)
- Testing
- Digitally supported prehabilitation program
- Where
- Austria
- Volunteers
- 40 people
- Sponsor
- Ludwig Boltzmann Institute for Digital Health and Prevention
Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting (CABG)
Colchicine for the Prevention of Post-Operative Atrial Fibrillation After Coronary Artery Bypass Grafting: A Single-Center, Strategy-Stratified, Randomized, Double-Blind, Placebo-Controlled Trial
Post-operative atrial fibrillation after coronary artery bypass grafting (CABG)
- Trial name
- NCT07611019
- Testing
- Colchicine 0.5 MG oral tablet twice daily
- Where
- Taiwan
- Volunteers
- 400 people
- Sponsor
- National Taiwan University Hospital
Intensive Care Unit, Coronary Artery Bypass Grafting (CABG)
Intravenous Fish Oil Based Lipid Emulsion to Enhance Recovery in High-Risk Cardiac Surgery Patients
The MODIFY CSX study is a prospective, randomized, placebo-controlled trial conducted in heart centers in Germany and Italy. A total of 550 high-risk cardiac surgery patients will receive either 0.20 g fish oil/kg body weight…
- Conditions
- Intensive Care Unit, Coronary Artery Bypass Grafting (CABG), High Risk Patients, Cardiopulmonary Bypass
- Trial name
- MODIFY CSX (NCT06279793)
- Testing
- Fish Oil, Intravenous 0.9% Sodium Chloride
- Where
- 10 sites in Germany
- Volunteers
- 550 people
- Sponsor
- GCP-Service International West GmbH
Postoperative Pain Following Coronary Artery Bypass Grafting (CABG)
Combined SPSP and TTP Blocks for Postoperative Analgesia Post-CABG
The goal of this clinical trial is to learn if combining two ultrasound-guided nerve blocks - one for the front of the chest and one for the side of the chest - works better than standard pain medications alone to treat pain…
- Trial name
- PACT (NCT07658521)
- Testing
- Transversus Thoracic Plane Block, Transversus Thoracic Plane (TTP) Block, Conventional Systemic Analgesia
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Percutaneous Coronary Intervention, Valve Repair/Replacement
Cardiac Rehab Referral Nudges
Investigators will evaluate the effectiveness of two different EHR-embedded nudges to improve referral to cardiac rehabilitation.
- Conditions
- Percutaneous Coronary Intervention, Valve Repair/Replacement, Coronary Artery Bypass Grafting
- Trial name
- NCT07607522
- Testing
- EHR Nudges
- Where
- United States
- Volunteers
- 7,000 people
- Sponsor
- NYU Langone Health
Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury
Trajectory-Based Phenotyping After Coronary Artery Bypass Surgery
Coronary artery bypass grafting is a commonly performed heart surgery, but patients may have different risks for postoperative complications even when their preoperative risk scores are similar.
- Conditions
- Coronary Artery Bypass Grafting, Postoperative Acute Kidney Injury, Postoperative Complications, Risk Stratification
- Trial name
- NCT07598682
- Testing
- Early Postoperative Phenotype Classification
- Where
- Turkey (Türkiye)
- Volunteers
- 1,000 people
- Sponsor
- Bursa Sevket Yilmaz Training and Research Hospital
Cardio-pulmonary Bypass, Cardiovascular Diseases
Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Prevention of CAD by targeting modifiable factors remains a key public health priority. L-Ascorbic Acid (Vitamin C - Vit.
- Conditions
- Cardio-pulmonary Bypass, Cardiovascular Diseases, Omega-3 Polyunsaturated Fatty Acids, Omega-3 Supplementation
- Trial name
- NCT06995586
- Testing
- Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose
- Where
- Cyprus
- Volunteers
- 108 people
- Sponsor
- Nicosia General Hospital
Coronary Artery Bypass Grafting Surgery (CABG)
SSVC-CI During CABG
To investigate the superior vena cava collapsibility index (SVC-CI), measured via transesophageal echocardiography (TEE), as a marker of fluid responsiveness. Two groups will be compared in this study.
- Trial name
- SVC-CI (NCT06645327)
- Testing
- a change in operating room table position, which will mimic an IV fluid bolus
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Milton S. Hershey Medical Center
Coronary Artery Disease, Coronary Artery Bypass Grafting
Ticagrelor-Based Dual Antiplatelet Therapy Duration in CABG
This randomized controlled trial aims to evaluate the impact of different durations of Ticagrelor-based dual antiplatelet therapy (DAPT) on saphenous vein graft (SVG) patency in patients undergoing coronary artery bypass grafting…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Saphenous Vein, Dual Antiplatelet Therapy
- Trial name
- NCT06981390
- Testing
- Ticagrelor + Aspirin for 3 Months (followed by aspirin monotherapy), Ticagrelor + Aspirin for 6 Months (followed by aspirin monotherapy), Ticagrelor + Aspirin for 12 Months (followed by aspirin monotherapy)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Kexiang Liu, MD
Coronary Artery Disease, Coronary Artery Bypass Grafting
Total Arterial vs. Mixed Grafting in Left Coronary CABG
This is a prospective, randomized, double-blind controlled trial comparing the clinical efficacy of total arterial grafting (internal thoracic artery and radial artery) versus conventional mixed grafting (internal thoracic artery…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Arterial Graft, Graft Patency
- Trial name
- NCT07057713
- Testing
- Total Arterial Grafting, Conventional Mixed Grafting
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Second Hospital of Jilin University
Coronary Artery Bypass Grafting, Heart Valve Disease
LLM-Based Intelligent Health Management Assistant in Life-Cycle Health Management of Cardiac Surgery Patients
This is a single-center, prospective, randomized, open-label, parallel-controlled clinical study to evaluate the effectiveness of a large language model (LLM)-based intelligent health management assistant in the life-cycle health…
- Conditions
- Coronary Artery Bypass Grafting, Heart Valve Disease, Aortic Aneurysm, Aortic Dissection
- Trial name
- cFT-LLM (NCT07521488)
- Testing
- LLM-Based Intelligent Health Management Assistant
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Anzhen Hospital
Heart Diseases, Coronary Artery Disease
Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women
The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grafting (SAG).
- Conditions
- Heart Diseases, Coronary Artery Disease, Coronary Artery Bypass Grafting
- Trial name
- ROMA:Women (NCT04124120)
- Testing
- Single arterial graft, Multiple arterial grafting
- Where
- 146 sites in United States, Australia and 24 more
- Volunteers
- 2,300 people
- Sponsor
- Weill Medical College of Cornell University
Coronary Artery Bypass Grafting (CABG)
Improving the Quality of Coronary Artery Bypass Grafting
This is a healthcare quality improvement study focused on increasing the utilization of arterial grafts in isolated coronary artery bypass grafting (CABG).
- Trial name
- CABG Quality (NCT07377149)
- Testing
- Interventions for healthcare professionals in hospitals with low usage rates, Interventions for healthcare professionals in hospitals with high usage rates
- Volunteers
- 8,700 people
- Sponsor
- China National Center for Cardiovascular Diseases