Clinical trials: Coronary Angiography, open to volunteers
Contrast-induced Acute Kidney Injury (CI-AKI) Following Coronary Angiogram (CI-AKI), Contrast-induced Nephropathy Following Coronary Angiogram (CIN)
Effectiveness of Remote Ischemic Preconditioning for Prevention of Contrast Induced Acute Kidney Injury in Patients Undergoing Coronary Angiograms.
The use of imaging is increasing in clinical practice, either for diagnosis or intervention. In these imaging processes, contrast medium (CM) is widely used.
- Trial name
- RIP-CI-AKI (NCT05147831)
- Testing
- Remote Ischemic Preconditioning
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Femoral Arterial Sheath Removal, Stress Ball
Effect of Stress Ball Use During Femoral Arterial Sheath Removal After Coronary Angiography
This randomized controlled trial aims to evaluate the effects of stress ball use during femoral arterial sheath removal after coronary angiography on pain, anxiety, patient satisfaction, and hemodynamic parameters.
- Conditions
- Femoral Arterial Sheath Removal, Stress Ball, Pain, Anxiety
- Trial name
- NCT07808632
- Testing
- Stress Ball
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Mersin University
Coronary Disease, Angiography
The Effect of Position on Pain, Bleeding, Hematoma and Vital Signs After Transfemoral Coronary Angiography
In this study, it was aimed to determine the effect of the special position given to the patient after transfemoral coronary angiography (supine position that varies depending on the angles) on pain, bleeding, hematoma and vital…
- Trial name
- NCT06795308
- Testing
- Bed Position and Head Elevation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mersin University
Coronary Artery Disease, Coronary Computed Tomography Angiography
Myocardial Perfusion Quantification With SPECT Using Multi-Pinhole Collimator Compared to Photon-Counting Coronary CTA
This prospective study aims to compare functional abnormalities detected using myocardial perfusion SPECT imaging (MPI SPECT) with the extent and severity of anatomical findings on coronary computed tomography angiography…
- Conditions
- Coronary Artery Disease, Coronary Computed Tomography Angiography, SPECT, Heart Diseases
- Trial name
- MY-FUSION (NCT06670768)
- Testing
- Stress Dynamic MPI SPECT, Stress Static MPI SPECT, Rest Dynamic MPI SPECT
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- Semmelweis University
Radial Artery Access, Distal Radial Artery Access (dTRA)
UltraSound Guided Distal Radial Artery vS Conventional Transradial Access for Interventional Coronary Angiography
Comparative study of ultrasound-guided distal radial access versus conventional radial access regarding the incidence of vascular access crossover.
- Trial name
- US-DRASTIC (NCT07617259)
- Testing
- coronary angiography
- Where
- Greece
- Volunteers
- 1,400 people
- Sponsor
- University Hospital of Patras
Cardiovascular Diseases, Hypertrophic Cardiomyopathy (HCM)
AI-enabled Screening and Diagnosis of Cardiomyopathies Using Coronary CTA
The goal of this observational and diagnostic study is to develop and validate an artificial intelligence assisted approach for coronary computer tomography angiography-(CCTA)-based screening and diagnosis of cardiomyopathies in…
- Conditions
- Cardiovascular Diseases, Hypertrophic Cardiomyopathy (HCM), Dilated Cardiomyopathy (DCM), Restrictive Cardiomyopathy
- Trial name
- Atlantis (NCT06748261)
- Testing
- CCTAI model
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Coronary Artery Disease Left Main, Coronary Artery Disease
Fractional Flow Reserve Versus Angiography for Treatment-Decision and Evaluation of Significant Left MAIN Coronary Artery Disease
The primary purpose of the study was to determine whether the 2-year probability of major adverse cardiac events (primary composite outcome) differed significantly between patients who underwent angiography-guided Percutaneous…
- Trial name
- FATE-MAIN (NCT05829889)
- Testing
- FFR-Guided PCI, Angiography-Guided PCI
- Where
- 49 sites in Hong Kong, India and 3 more
- Volunteers
- 960 people
- Sponsor
- Seung-Jung Park
Cardiac Congenital Defects
Coronary Arteries Anomalies by CT in Children With CHD
Delineate coronary artery anatomy and detection of coronary anomalies in children with complex cardiac anomalies by cardiac CT-angiography before total surgical correction.
- Trial name
- NCT06381128
- Testing
- Cardiac CT
- Volunteers
- 100 people
- Sponsor
- Assiut University
Type 2 Diabetes Mellitus (T2DM), Coronary Artery Disease
SGLT2 Inhibitors on Coronary Atherosclerosis Progression Via Perivascular Adipose Tissue in Diabetes
This study is a multicenter, randomized controlled trial to test whether an SGLT2 inhibitor (dapagliflozin), a type of diabetes medication, can slow down or even reverse the progression of coronary atherosclerosis (plaque buildup…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Coronary Artery Disease, Atherosclerosis
- Trial name
- SCOPE (NCT07614230)
- Testing
- Dapagliflozin (DAPA), Standard Care (Treatment as Usual)
- Where
- 2 sites in China
- Volunteers
- 144 people
- Sponsor
- Junjie Yang
Coronary Arterial Disease (CAD), Radial Artery Spasm
Impact of Preprocedural Stress Ball Use on Radial Artery Outcomes in Elective Coronary Angiography
This randomized, double-blind, controlled trial aims to evaluate the effect of preprocedural hand exercise using a stress ball on the incidence of radial artery spasm and other vascular complications in patients undergoing…
- Conditions
- Coronary Arterial Disease (CAD), Radial Artery Spasm, Radial Artery Occlusion, Transradial Angiogram
- Trial name
- SPARROW (NCT07087522)
- Testing
- Stress Ball Use
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people
- Sponsor
- Sakarya University
Cardiogenic Shock
Randomized Evaluation of Istaroxime for Stabilization in Acute Heart Failure-Cardiogenic Shock
The goal of this clinical trial is to learn if the drug istaroxime works to treat cardiogenic shock due to acute heart failure in adults. It will also learn about the safety of istaroxime.
- Trial name
- RESCUE HF-CS (NCT07583446)
- Testing
- istaroxime
- Where
- Armenia
- Volunteers
- 600 people
- Sponsor
- Seismic Pharmaceuticals Operations LLC
Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary Syndrome
Angio-based Final Functional Effect of PCI
Fractional flow reserve (FFR) has revolutionized the diagnosis and treatment of coronary artery disease (CAD), and more recently, post percutaneous coronary intervention (post-PCI) FFR has emerged as an independent predictor of…
- Conditions
- Acute Coronary Syndrome, Non ST Segment Elevation Acute Coronary Syndrome, Chronic Coronary Syndrome
- Trial name
- AFFE-PCI (NCT06255678)
- Testing
- Angiography-based vessel fractional flow reserve (vFFR) calculation
- Where
- Poland
- Volunteers
- 2,005 people
- Sponsor
- Medical University of Warsaw
Coronary Arterial Disease (CAD), Coronary Arteriosclerosis
PRogression of Atheroma Evaluated by CT Angiography and IntraCoronary Imaging tEchniques
This is a combined cohort study with retrospectively and prospectively enrolled coronary artery disease (CAD) patients. All the patients will undergo clinical follow-up for up to 5 years, and repeat coronary CTA will be conducted…
- Trial name
- PRACTICE (NCT06794684)
- Where
- 2 sites in China
- Volunteers
- 50,000 people
- Sponsor
- Ruijin Hospital
Cardiovascular Diseases, Myocardial Ischemia
A Prospective, Multicenter, Randomized Controlled Trial to Investigate the Value of Coronary CT Angiography in the Understanding and Management of Coronary Calcium (The Optimal Trial)
The OPTIMAL randomized clinical trial has been designed to compare two imaging strategies and to test the hypothesis that a calcium modification strategy informed by coronary CT angiography (CCTA) will improve procedural…
- Conditions
- Cardiovascular Diseases, Myocardial Ischemia, Heart Diseases, Arteriosclerosis
- Trial name
- NCT07286578
- Testing
- CT(Computed Tomography) guided Percutaneous Coronary Intervention, IVUS (Intravascular Ultrasound) guided Percutaneous Coronary Intervention
- Where
- 15 sites in United States, Belgium and 2 more
- Volunteers
- 700 people
- Sponsor
- Fundación EPIC
Non-ST Elevation Myocardial Infarction, Acute Coronary Syndrome
Cardiac MRI Prior to Invasive Coronary Angiography in Patients With Suspected Non-ST-Elevation Myocardial Infarction
Patients with a suspected myocardial infarction are subdivided into ST-elevation and non-ST-elevation myocardial infarctions (STEMI and NSTEMI, respectively) using ECG.
- Trial name
- KaPSICA-CMR (NCT06566625)
- Testing
- Cardiac MRI (CMR) examination
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Region Stockholm
ACS (Acute Coronary Syndrome), SGLT2 Inhibitors
CCTA Evaluation of SGLT2i-related Pericoronary Fat Changes Patients With Stage 4 CKM Syndrome
The aim of this clinical trial is to investigate whether dapagliflozin (a sodium-glucose cotransporter 2 inhibitor, SGLT2i) can reduce levels of coronary inflammation in patients with stage 4 CKM syndrome.
- Trial name
- DAPA-PCAT (NCT07351643)
- Testing
- Dapagliflozin
- Where
- China
- Volunteers
- 110 people
- Sponsor
- Shenyang Northern Hospital
Coronary Disease, Coronary Arteriosclerosis
Effects of a Healthy Nordic Diet on Atherosclerosis in Patients with Coronary Heart Disease
Diet can play a key role in atherosclerosis and coronary heart disease (CHD), but little interventional data exists, and the mediators of possible anti-atherosclerotic effects of diet are unclear.
- Conditions
- Coronary Disease, Coronary Arteriosclerosis, Myocardial Infarction, Chronic Coronary Syndrome
- Trial name
- NORDHEART (NCT06701968)
- Testing
- Healthy Nordic Diet, Usual Care
- Where
- Sweden
- Volunteers
- 150 people
- Sponsor
- Uppsala University
Severe Aortic Stenosis
Transfemoral TAVI With or Without Coronary Angiogram in Patients With Severe Aortic Stenosis (PURE TAVI)
This study will be conducted in patients with severe aortic stenosis who are referred for transcatheter aortic valve implantation (TAVI). TAVI is the recommended treatment for severe aortic stenosis.
- Trial name
- PURETAVI (NCT06898086)
- Testing
- Transcatheter aortic valve implantation
- Where
- 23 sites in Austria, Czechia and 5 more
- Volunteers
- 620 people
- Sponsor
- Rede Optimus Hospitalar SA
Vascular Access, Coronary Interventions
Vascular Access Registry
The Vascular Access Registry (VARegistry) is a prospective patient registry that will be conducted at the Hemodynamic Laboratory of the Cardiology Clinic of the University General Hospital of Patras.
- Trial name
- VARegistry (NCT06942260)
- Where
- Greece
- Volunteers
- 1,157 people
- Sponsor
- University Hospital of Patras
Healthy, Angiography
Effect of Teach-Back Method in Angiography
This study aims to evaluate the effect of discharge training with Teach-Back Method on anxiety, fear of death and knowledge level in patients undergoing coronary angiography.
- Trial name
- NCT06959303
- Testing
- Teach Back Education
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Tarsus University