Clinical trials: Control
Cocaine Dependence
A Placebo-Controlled Double-Blind Combined Treatment of Modafinil and CBT for Cocaine Dependence
The purpose of this study is to test whether a cognitive behavioral therapy (CBT) and a medication called modafinil, which is approved to treat sleep disorders, will help individuals who are abusing cocaine.
- Trial name
- NCT00344565
- Testing
- Modafinil, Cognitive Behavioral Therapy--Relapse Prevention
- Volunteers
- 15 people
- Sponsor
- Research Foundation for Mental Hygiene, Inc.
Dermatitis, Dermatitis, Atopic
Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects
B7451014 is a Phase 3 study to investigate PF-04965842 in patients aged 12 years and over with a minimum body weight of 40 kg who have moderate to severe atopic dermatitis.
- Conditions
- Dermatitis, Dermatitis, Atopic, Eczema, Skin Diseases
- Trial name
- NCT03627767
- Testing
- PF-04965842 100 mg, PF-04965842 200 mg
- Where
- 235 sites in United States, Argentina and 19 more
- Volunteers
- 1,235 people
- Sponsor
- Pfizer
Recurrent Vestibulopathy
Effect of Renexin Tablet in Patients With Recurrent Vestibulopathy
The purpose of this study is to determine whether Renexin is effective in the treatment of vestibular symptoms in patients with recurrent vestibulopathy.
- Trial name
- REREV (NCT01895400)
- Testing
- Renexin (cilostazol 100mg + gingko biloba extract 80 mg)
- Where
- South Korea
- Volunteers
- 26 people
- Sponsor
- Jong Woo Chung
Anesthesia, Hemodynamic Instability
Anesthesia Induction with the Target-controlled Infusion of Propofol in High-risk Patients
The purpose of this study is to compare the risk of hypotension following induction of anesthesia in high-risk patients (American Society of Anesthesiologists risk scores III and IV) using target-controlled infusion (TCI) of…
- Trial name
- NCT06535230
- Testing
- Manual anesthesia induction, Anesthesia induction with Target controlled infusions (TCI), Hemodynamic monitoring with pressure recording analytical method (PRAM)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Acibadem University
Vasomotor Symptoms, Cardiovascular Health
Vasomotor Symptoms and Cardiovascular Control
The purpose of this study is to preliminarily determine whether the frequency and/or severity of vasomotor symptoms (VMS) at baseline, and then after symptom reduction with gabapentin, relates to various cardiovascular control…
- Trial name
- NCT02202707
- Testing
- Gabapentin
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Neck Pain
Neck Motion and Motor Control in Chronic Neck Pain and Associations With Clinical Symptoms
The primary purpose of this study is to investigate if there is altered motor control of head and neck in chronic neck pain patients compared with healthy persons.
- Trial name
- NCT01778036
- Where
- 2 sites in Norway
- Volunteers
- 84 people
- Sponsor
- Norwegian University of Science and Technology
Acne Vulgaris
Bioequivalence of Adapalene Topical Gel in Patients With Acne Vulgaris
The objective of this study was to evaluate the efficacy and safety of the test formulation of adapalene gel 0.1% (PLIVA Research \& Development Ltd.) as compared to the already marketed formulation, Differin® (adapalene 0.1%)…
- Trial name
- NCT01182636
- Testing
- Adapalene, Differin®
- Where
- 22 sites in United States, Belize
- Volunteers
- 601 people
- Sponsor
- Teva Pharmaceuticals USA
Allergic Conjunctivitis
The INVIGORATE Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.
The INVIGORATE Trial: A Randomized, Double-masked, Crossover Design, Phase 3 Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.
- Trial name
- NCT04207736
- Testing
- Reproxalap Ophthalmic Solution (0.25%), Vehicle Ophthalmic Solution
- Where
- Canada
- Volunteers
- 95 people
- Sponsor
- Aldeyra Therapeutics, Inc.
Measles Vaccine, Hospital Admission
Measles Vaccination at Health System Contacts
In addition to protecting against measles infection, measles vaccine (MV) strengthens the individual's ability to combat infections in general - MV has beneficial non-specific effects (NSE) lowering the risk of death and…
- Conditions
- Measles Vaccine, Hospital Admission, Mortality, Non-specific (Heterologous) Effects of Vaccines
- Trial name
- NCT04220671
- Testing
- measles vaccine, Saline
- Where
- Guinea-Bissau
- Volunteers
- 5,400 people
- Sponsor
- Bandim Health Project
Ulcerative Colitis
GI-270384 Study In Patients With Mild To Moderate Ulcerative Colitis
The aim of this double blind, placebo controlled, study is to evaluate activity consistent with efficacy provided by 14 days administration of GI270384X, and to provide preliminary pharmacokinetics and safety/tolerability of 14…
- Trial name
- NCT00457171
- Testing
- GI-270384
- Volunteers
- 16 people
- Sponsor
- GlaxoSmithKline
De Novo Renal Transplant Recipient.
Fixed Dose MMF vs Concentration Controlled MMF After Renal Transplantation
Determine the value of a clinically feasible strategy of therapeutic drug monitoring compared with fixed dosing in de novo MMF treated renal transplant recipients with respect to the incidence of treatment failure.
- Trial name
- NCT00166244
- Testing
- Mycophenolate Mofetil
- Where
- 67 sites in Australia, Austria and 17 more
- Volunteers
- 901 people
- Sponsor
- Erasmus Medical Center
Healthy
The Safety and Tolerability of STSA-1002 Following Intravenous Infusion in Healthy Subjects
A randomized,double-blind,placebo-controlled,single-ascending dose phase Ⅰa study to evaluate the safety,tolerability,pharmacokinetics and pharmacodynamics of STSA-1002 following intravenous infusion in healthy subjects
- Trial name
- NCT05032144
- Testing
- STSA-1002 injection
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Staidson (Beijing) Biopharmaceuticals Co., Ltd
Asthma
Dose Ranging Study Evaluating the Efficacy and Safety of GSK2190915 Administered Once Daily
To evaluate the efficacy, dose response and safety of four doses of GSK2190915 in tablet form (10mg, 30mg, 100mg and 300mg) administered once daily, over 8 weeks compared with placebo in adolescent and adult subjects (12 years of…
- Trial name
- NCT01147744
- Testing
- Fluticasone Propionate 100mcg via ACCUHALER/DISKUS, GSK2190915 100mg, GSK2190915 10mg
- Where
- 84 sites in United States, Bulgaria and 4 more
- Volunteers
- 700 people
- Sponsor
- GlaxoSmithKline
Lung Disease
Evaluation of the Hospital2Home Palliative Care Service for Patients With Advanced Progressive Lung Disease
The investigators hypothesise that H2H will result in improved symptom control and quality of life and may be more cost-effective than standard best practice.
- Trial name
- H2H-ILD (NCT01450644)
- Testing
- The Hospital2Home Service
- Where
- 2 sites in United Kingdom
- Volunteers
- 52 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Tension Headache
The Effectiveness of Pharmacopuncture on Acute Tension Headache
This study is a double blind, randomized controlled trail. condition/disease: acute tension headache treatment/intervention: Pharmacopuncture
- Trial name
- NCT05549765
- Testing
- Pharmacopuncture, Korean medical treatment
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Jaseng Medical Foundation
Adrenal Suppression, Hemodynamic Instability
THe Comparison of Target Controlled Infusion of Propofol or Etomidate at General Anesthesia in Geriatric Patients
Compare the efficacy and safety of closed-loop target controlled infusion of propofol or etomidate at general anesthesia in geriatric patients
- Trial name
- NCT02111265
- Testing
- Remifentanil, Cisatracurium, Sufentanil
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Head and Neck Squamous Cell Carcinoma
Postoperative Radiotherapy With Nimotuzumab ± Benmelstobart in Intermediate-Risk Head and Neck Squamous Cell Carcinoma
A multicenter, randomized, controlled, open-label, Phase II/III clinical trial designed to evaluate the efficacy and safety of postoperative radiotherapy combined with Nimotuzumab,with or without Bemcentinib, in postoperative…
- Trial name
- NimoBenSeq (NCT07535567)
- Testing
- Nimotuzumab, Nimotuzumab, Benmelstobart, Postoperative Radiotherapy
- Volunteers
- 386 people
- Sponsor
- Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University
Compare Operational Performance of Three Technology in Lung Models
The Assessment of the Feasibility and Operational Performance of Automated System Bronchoscopy in a Simulated Environment
Recruit 30 trainee physicians from 6 centers and compare their performance in operating lung models using automatic bronchoscopy, robotic bronchoscopy, and electromagnetic navigation bronchoscopy.
- Trial name
- NCT06741267
- Testing
- RBS, AB, ENB
- Where
- Chad
- Volunteers
- 30 people
- Sponsor
- Guangzhou Medical University
Pilonidal Sinus, Pilonidal Disease
The Role of Mesenchymal Stem Cell and Exosome in Treating Pilonidal Sinus Disease in Children
Chronic wounds that fail to heal over extended periods pose a significant financial burden on the healthcare system, underscoring the urgent need to enhance clinical treatments.
- Trial name
- NCT06391307
- Testing
- Crystallized phenol, Crystallized phenol + Exosome, Crystallized phenol + Stem Cell
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Mustafa Azizoğlu
Stroke
Very Early Rehabilitation in Acute Ischemic Stroke
The purpose of this study is to evaluate the effectiveness of a rehabilitation (physiotherapy) program in patients with acute ischemic stroke in Acute Vascular Unit and in general ward of Hospital de Clínicas de Porto Alegre, and…
- Trial name
- VERIS-Brazil (NCT01694992)
- Testing
- Early mobilization
- Where
- Brazil
- Volunteers
- 184 people
- Sponsor
- Hospital de Clinicas de Porto Alegre