Clinical trials: Contrast Induced Nephropathy
Contrast-induced Nephropathy, Statin
Effects Of Combination Therapy Of Statin And Ascorbic Acid For Prevention Of Contrast-Induced Nephropathy
To evaluate the benefit for statin use in prevention of of CI-AKI after computed tomography urogram (CTU).
- Conditions
- Contrast-induced Nephropathy, Statin, Ascorbic Acid, AKI
- Trial name
- NCT03391830
- Testing
- Atorvastatin-Ascorbic acid
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Mansoura University
Coronary Artery Disease, Angina, Unstable
Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease
The goal of the study is to assess the prevalence of contrast-associated acute kidney injury in patients with stable coronary artery disease, ST-elevation myocardial infarction and unstable angina/NSTEMI, assess the risk factors…
- Conditions
- Coronary Artery Disease, Angina, Unstable, Angina, Stable, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT04163484
- Testing
- Iodinated contrast
- Where
- Russia
- Volunteers
- 156 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Myocardial Infarction, Death
Prognostic Impact of Organ Damage in STEMI Patients
Besides contrast-induced acute kidney injury (CI-AKI), adscititious vital organ damage such as hypoxic liver injury (HLI) may affect the survival in patients with ST-elevation myocardial infarction (STEMI).
- Conditions
- Myocardial Infarction, Death, Acute Kidney Injury, Hepatic Insufficiency
- Trial name
- NCT02800421
- Volunteers
- 668 people
- Sponsor
- Inha University Hospital
Contrast Induced Nephropathy
Hydration and Contrast-Induced Nephropathy in Primary Angioplasty
The purpose of this study is to determine whether hydration with sodium bicarbonate is more effective than hydration with sodium chloride to prevent contrast induced nephropathy in patients undergoing Primary Coronary…
- Trial name
- NCT00770614
- Testing
- sodium bicarbonate solution, Isotonic saline
- Where
- Italy
- Volunteers
- 450 people
- Sponsor
- Ospedale Misericordia e Dolce
Acute Kidney Injury
Aminophylline and Contrast Induced Nephropathy in Acute Myocardial Infarction
The purpose of this study is to determine whether additional therapy with Aminophylline to hydration with sodium bicarbonate and administration of N-acetylcysteine is more effective to prevent contrast induced acute kidney injury…
- Trial name
- NCT01594489
- Testing
- Aminophylline, Hydration plus N-acetylcisteine
- Where
- Italy
- Volunteers
- 250 people
- Sponsor
- Ospedale Misericordia e Dolce
Contrast Induced Nephropathy
Prevention of Contrast Induced Nephropathy With Sodium Bicarbonate
This will be a randomized controlled trial closely following the original protocol in the previous study published in JAMA 2004 by Merten et al. Patients will be randomly assigned to one of two treatment groups.
- Trial name
- NCT00392405
- Testing
- 3 amps of sodium bicarbonate mixed in one liter of D5W
- Where
- United States
- Volunteers
- 656 people
- Sponsor
- Norton Community Hospital
Aortic Aneurysm, Contrast Induced Nephropathy
Computed Tomography Arteriograms (CTA) Volume Dose Reduction Study
The purpose of the study is to determine if the dose of contrast (Omnipaque) administered for Computed Tomography Arteriograms (CTA) can be reduced without degradation of image quality.
- Conditions
- Aortic Aneurysm, Contrast Induced Nephropathy, Aortic and Arterial Anomalies
- Trial name
- NCT02669784
- Testing
- Low Dose Contrast (Omnipaque) 40mL, Low Dose Contrast (Omnipaque) 50 mL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Milton S. Hershey Medical Center
Kidney Injury, Contrast-induced Nephropathy
Early Diagnosis as Strategy in Reducing the Incidence of Contrast-induced Nephropathy
Renal damage due to contrast media (CM) administration is one of the main complications of cardiac intervention and is called contrast-induced nephropathy (CIN).
- Trial name
- NCT04225013
- Testing
- Early kidney damage biomarkers, Predisposition to kidney injury biomarkers
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- R. Laura Vicente Vicente
Renal Failure
Sodium Bicarbonate for Prevention of Contrast-Induced Nephropathy
The purpose of this study is to determine whether hydration with sodium bicarbonate is superior to hydration with saline to prevent contrast-induced nephropathy.
- Trial name
- NCT01172353
- Testing
- sodium bicarbonate, saline
- Where
- Brazil
- Volunteers
- 301 people
- Sponsor
- Hospital Sao Lucas da PUCRS
Non ST Segment Elevation Acute Coronary Syndrome, Contrast Induced Nephropathy
Supplementation With Beetroot Juice to Prevent Contrast Associated Nephropathy During Hospitalization for Acute Coronary Syndrome Without ST Elevation
The goal of this study is to compare the possible beneficial effect of beetroot juice supplementation versus the usual management during hospitalization to prevent contrast-induced nephropathy after cardiac catheterizations.
- Trial name
- RENACS (NCT06695429)
- Testing
- Beetroot juice
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Hospital General Universitario Santa Lucia
Nephropathy
Efficacy of Statins In Prevention of CIN
To determine if statin therapy plus intravenous normal saline, in patients with chronic renal insufficiency undergoing angiography, is superior to placebo plus intravenous normal saline therapy in the prevention of CIN.
- Trial name
- SCIN (NCT01071993)
- Testing
- atorvastatin
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Contrast-induced Nephropathy Following Percutaneous Intervention (CIN)
Efficacy and Safety of a Beet-Derived Inorganic Nitrate-Based Food Product for the Prevention of Contrast-Induced Nephropathy in High-Risk Patients Undergoing Percutaneous Coronary Intervention
Contrast-induced nephropathy (CIN) is a common complication in high-risk patients undergoing percutaneous coronary intervention (PCI) due to exposure to iodinated contrast agents.
- Trial name
- BEET-CIN (NCT06984406)
- Testing
- Beet-Derived Inorganic Nitrate-Based Food Product
- Where
- Russia
- Volunteers
- 88 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Contrast Induced Nephropathy
PREdictive Value of COntrast voluMe to creatinINe Clearance Ratio
To determine a relatively safe contrast media volume to creatinine clearance cut-off value to avoid contrast-induced nephropathy in patients following coronary angiography
- Trial name
- PRECOMIN (NCT01400295)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Guangdong Provincial People's Hospital
Contrast Induced Acute Kidney Injury
Contrast-inDuced nephRotoxicity as Assessed by the KIdney Load-to-DAmage RElationship
We previously demonstrated that the slope of the relationship plotting individual iodine loads against contrast-induced serum creatinine changes ( the load-to-damage relationship, LDR) characterizes the intrinsic nephrotoxicity…
- Trial name
- DrKILDARE (NCT01908309)
- Testing
- Iobitridol 350, Iodixanol 320
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Azienda Sanitaria Locale 9, Grosseto
Chronic Kidney Disease Stage 2, Radiographic Contrast Agent Nephropathy
N-Acetyl Cystein and Contrast Nephropathy
There are many controversies about the role of N-Acetyl Cystein in preventing of contrast nephropathy. These contradictory results may be due to different criteria for patients' selection, different end points, different type and…
- Trial name
- NCT01820195
- Testing
- Oral N-Acetyl Cystein, IV N-Acetyl Cystein
- Where
- Iran
- Volunteers
- 549 people
- Sponsor
- Imam Khomeini Hospital
Renal Insufficiency, Contrast Medium-induced Renal Insufficiency
Renal PRotection Against Contrast mEdium-induced nephroPathy in High Risk Patients undErgoing Coronary Angiography
This study evaluates the efficacy of remote ischemic preconditioning on preventing contrast medium-induced nephropathy in a population of high risk patients undergoing coronary angiography.
- Trial name
- PREPARE (NCT02463604)
- Testing
- Coronary Angiography
- Where
- France
- Volunteers
- 220 people
- Sponsor
- University Hospital, Angers
Kidney Failure, Chronic
A Safety Comparison of Iopromide and Iodixanol in Renal Impaired Patients
The investigators intend to find out which contrast agent has less kidney toxicity in renal impaired patients undergoing cardiac angiography or percutaneous coronary intervention (PCI).
- Trial name
- DIRECT (NCT00926562)
- Testing
- Iopromide (Ultravist), Iodixanol (Visipaque)
- Where
- 19 sites in China
- Volunteers
- 592 people
- Sponsor
- Chinese PLA General Hospital
Acute Kidney Injury
Remote Ischemic Preconditioning and Risk of Contrast-Induced Acute Kidney Injury in Patients Undergoing Coronary Stent Implantation
This single-center, randomized controlled trial is to investigate the impact of remote ischemic preconditioning (RIPC) on the risk contrast-induced acute kidney injury and its long-term impact on renal function for patients with…
- Trial name
- REPAIR (NCT01827891)
- Testing
- remote ischemic preconditioning (RIPC)
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Beijing Anzhen Hospital
Cardio-Renal Syndrome, Coronary Angiography
Risk Factors and Prognosis of Adverse Cardiovascular and Kidney Events After Coronary Intervention II
As a multi-center, retrospective observation study in southern China, this study included the main study population of patients who underwent coronary angiography at 5 hospitals from Guangzhou, Shenzhen, Yangjiang, Maoming and…
- Conditions
- Cardio-Renal Syndrome, Coronary Angiography, Coronary Artery Disease, Kidney Diseases
- Trial name
- NCT05050877
- Where
- China
- Volunteers
- 184,855 people
- Sponsor
- Guangdong Provincial People's Hospital
Remote Ischaemic Preconditioning, Contrast Induced Nephropathy
Use of Remote Ischaemic Preconditioning in the Prevention of Contrast Induced Nephropathy
With an increasingly ageing population the incidence of peripheral arterial disease (PAD) is rising. With approximately one quarter of all PAD patients ultimately progressing to Critical Limb Ischaemia (CLI), increased demands…
- Trial name
- NCT02516072
- Testing
- RIPC
- Where
- Singapore
- Volunteers
- 40 people
- Sponsor
- Changi General Hospital