Clinical trials: Contrast Induced Nephropathy
Contrast-induced Acute Kidney Injury (CI-AKI) Following Coronary Angiogram (CI-AKI), Contrast-induced Nephropathy Following Coronary Angiogram (CIN)
Effectiveness of Remote Ischemic Preconditioning for Prevention of Contrast Induced Acute Kidney Injury in Patients Undergoing Coronary Angiograms.
The use of imaging is increasing in clinical practice, either for diagnosis or intervention. In these imaging processes, contrast medium (CM) is widely used.
- Trial name
- RIP-CI-AKI (NCT05147831)
- Testing
- Remote Ischemic Preconditioning
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The University of Texas Medical Branch, Galveston
Contrast-Induced Nephropathy, Acute Kidney Injury
Uric Acid to Albumin Ratio for Predicting Contrast Associated Acute Kidney Injury After Cardiac and Non Cardiac Procedures
Contrast-associated acute kidney injury (CA-AKI) is a potential complication that can occur following exposure to iodinated contrast media during diagnostic and interventional procedures, contributing to prolonged hospital stays…
- Trial name
- NCT07855653
- Volunteers
- 100 people
- Sponsor
- Assiut University
ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN)
Beyond the Mehran Risk Score: Predictive Value of Total Ischemic Time for Contrast-Induced Nephropathy in ST Segment Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
Contrast-Induced Nephropathy (CIN) is a serious complication following primary percutaneous coronary intervention (PCI) in patients presenting with acute ST-segment elevation myocardial infarction (STEMI).
- Conditions
- ST Elevation (STEMI) Myocardial Infarction, Contrast Induced Nephropathy (CIN), Acute Kidney Injury
- Trial name
- NCT07826572
- Testing
- Total Ischemic Time Evaluation
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Assiut University
Contrast-Associated Acute Kidney Injury, Acute Kidney Injury
Contrast Volume as a Predictor of Kidney Injury Following Contrast-Enhanced CT
Iodinated contrast dye used during computed tomography (CT) scans can sometimes cause kidney stress or damage, known as contrast-associated acute kidney injury (CA-AKI).
- Conditions
- Contrast-Associated Acute Kidney Injury, Acute Kidney Injury, Contrast-Induced Nephropathy, Acute Renal Failure
- Trial name
- NCT07813819
- Volunteers
- 1,112 people
- Sponsor
- Assiut University
Acute Kidney Injury, Contrast-induced Nephropathy
Clinical Validation of the RENISCHEM L-FABP POC Assay
This study will involve measurement of levels of a novel urinary biomarker of renal ischemia, L-FABP. The purpose of the study is to perform a clinical validation of the ability of L-FABP measurements in urine using the RENISCHEM…
- Trial name
- SAKURA-POC (NCT04864847)
- Testing
- RENISCHEM L-FABP POC Test
- Where
- 6 sites in United States
- Volunteers
- 382 people
- Sponsor
- Hikari Dx, Inc.
Pentoxifylline, Contrast Induced Nephropathy
Pentoxifylline for Prevention of Contrast Induced Nephropathy in Chronic Kidney Diseased Patients in Intensive Care Unit
The aim of this study is to evaluate the effect of pentoxifylline for control of contrast induced nephropathy in chronic kidney diseased patients in intensive care unit.
- Conditions
- Pentoxifylline, Contrast Induced Nephropathy, Chronic Kidney Disease, Intensive Care Unit
- Trial name
- NCT07561801
- Testing
- Pentoxifylline, Normal saline
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Tanta University
Acute Ischemic Stroke, Contrast-induced Nephropathy
Serum Electrolytes and Contrast-Induced Nephropathy in Acute Ischemic Stroke Patients Undergoing Endovascular Treatment
This study aims to evaluate the relationship between serum electrolyte levels and the development of contrast-induced acute kidney injury (CI-AKI) in patients with acute ischemic stroke undergoing endovascular therapy (EVT).
- Conditions
- Acute Ischemic Stroke, Contrast-induced Nephropathy, Acute Kidney Injury
- Trial name
- NCT07546448
- Testing
- No intervention (observational cohort study)
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital
Acute Kidney Injury, Pulmonary Embolism
Acute Kidney Injury in Patients Undergoing Contrast Exposure: VQ vs. CT
Both, CT scans and VQ scans, are used by doctors to look for pulmonary embolism. The most common reason to order a VQ scan is to avoid the IV dye.
- Conditions
- Acute Kidney Injury, Pulmonary Embolism, Contrast-induced Nephropathy
- Trial name
- VQ/CT (NCT03116139)
- Testing
- V/Q imaging, Computed tomography scan
- Where
- 5 sites in United States
- Volunteers
- 253 people
- Sponsor
- Indiana University
Contrast-Associated Acute Kidney Injury, Contrast-induced Nephropathy
Oral vs. Intravenous Hydration to Prevent Contrast-Associated Acute Kidney Injury in the ED
This study is planned to be conducted by emergency physicians between November 7, 2025, and December 7, 2026. Inclusion and Exclusion Criteria The study will include adult patients aged 18 years and older who are considered at…
- Trial name
- NCT07459413
- Testing
- Water, %0,9 NaCl
- Where
- Turkey (Türkiye)
- Volunteers
- 198 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Contrast-induced Nephropathy
Role of Amlodipine in Reduction of CIN
The aim is to assess the benefit of low dose oral amlodipine in renal protection from contrast induced nephropathy in diabetic patients in intensive care unit
- Trial name
- NCT07291375
- Testing
- Calcium channel blocker, Hydration
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Minia University
Acute Kidney Injury, Heart Failure
Remote Ischemic Preconditioning for Renal and Cardiac Protection in Congestive Heart Failure (RICH) Trial
This is a prospective, double-blind, sham-controlled, multicenter, randomized clinical trial is to study the effects of remote ischemic preconditioning on contrast-associated acute kidney injury, functional capacity, and major…
- Conditions
- Acute Kidney Injury, Heart Failure, Contrast Induced Nephropathy, Coronary Angiography
- Trial name
- RICH (NCT04982419)
- Testing
- Remote ischemic preconditioning
- Where
- 3 sites in United States
- Volunteers
- 240 people
- Sponsor
- VA Office of Research and Development
Contrast-Induced Nephropathy, Coronary Angiography
Effect of Continuing vs. Discontinuing ACE Inhibitors on Renal Function After Coronary Angiography
This clinical trial evaluates whether continuing or withholding ACE inhibitors (specifically Ramipril) before coronary angiography affects the risk of contrast-induced nephropathy (CIN).
- Conditions
- Contrast-Induced Nephropathy, Coronary Angiography, Acute Kidney Injury
- Trial name
- ACEI-RF (NCT07184918)
- Testing
- Continuing Ramipril, Withholding Ramipril
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Contrast-induced Nephropathy, Kidney Injury
Intravenous vs. Oral Hydration to Reduce the Risk of Post-Contrast Acute Kidney Injury After Intravenous Contrast-Enhanced Computed Tomography in Patients With Severe Chronic Kidney Disease
The use of contrast media (CM) poses a risk of post-contrast acute kidney injury (PC-AKI), especially among patients chronic kidney disease (CKD).
- Conditions
- Contrast-induced Nephropathy, Kidney Injury, Kidney Failure, Chronic, Risk Reduction
- Trial name
- ENRICH (NCT05283512)
- Testing
- Preventive treatment with IV-hydration, Preventive treatment with oral hydration
- Where
- Denmark
- Volunteers
- 254 people
- Sponsor
- Odense University Hospital
Ischaemic Heart Disease, Contrast-induced Nephropathy
Trial to Assess Whether Computed Tomography Cardiac Angiography Can Improve Invasive Coronary Angiography in Bypass Surgery Patients
A large number of patients with symptomatic ischaemic heart disease undergo coronary artery bypass grafting (CABG) to alleviate their symptoms and improve prognosis.
- Trial name
- BYPASS-CTCA (NCT07022626)
- Testing
- CTCA
- Where
- 2 sites in United Kingdom
- Volunteers
- 688 people
- Sponsor
- Barts & The London NHS Trust
Contrast Induced Nephropathy
Effects of Hydration to Prevent Contrast Induced Nephropathy in PCI for ST-elevation Myocardial Infarction.
The aim of the study is to test the efficacy of low versus high volume hydration and two different solutions (sodium chloride versus sodium bicarbonate) in preventing contrast induced nephropathy (CIN) in ST elevation myocardial…
- Trial name
- CINIMA (NCT00639912)
- Testing
- sodium chloride, sodium bicarbonate
- Where
- 5 sites in Italy
- Volunteers
- 599 people
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Contrast-induced Nephropathy Following Percutaneous Intervention (CIN)
Efficacy and Safety of a Beet-Derived Inorganic Nitrate-Based Food Product for the Prevention of Contrast-Induced Nephropathy in High-Risk Patients Undergoing Percutaneous Coronary Intervention
Contrast-induced nephropathy (CIN) is a common complication in high-risk patients undergoing percutaneous coronary intervention (PCI) due to exposure to iodinated contrast agents.
- Trial name
- BEET-CIN (NCT06984406)
- Testing
- Beet-Derived Inorganic Nitrate-Based Food Product
- Where
- Russia
- Volunteers
- 88 people
- Sponsor
- National Medical Research Center for Therapy and Preventive Medicine
Non ST Segment Elevation Acute Coronary Syndrome, Contrast Induced Nephropathy
Supplementation With Beetroot Juice to Prevent Contrast Associated Nephropathy During Hospitalization for Acute Coronary Syndrome Without ST Elevation
The goal of this study is to compare the possible beneficial effect of beetroot juice supplementation versus the usual management during hospitalization to prevent contrast-induced nephropathy after cardiac catheterizations.
- Trial name
- RENACS (NCT06695429)
- Testing
- Beetroot juice
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Hospital General Universitario Santa Lucia
Coronary Artery Disease, Angina, Unstable
Contrast-associated Acute Kidney Injury in Patients With Different Types of Coronary Artery Disease
The goal of the study is to assess the prevalence of contrast-associated acute kidney injury in patients with stable coronary artery disease, ST-elevation myocardial infarction and unstable angina/NSTEMI, assess the risk factors…
- Conditions
- Coronary Artery Disease, Angina, Unstable, Angina, Stable, STEMI - ST Elevation Myocardial Infarction
- Trial name
- NCT04163484
- Testing
- Iodinated contrast
- Where
- Russia
- Volunteers
- 156 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Kidney Injury, Contrast-induced Nephropathy
Early Diagnosis as Strategy in Reducing the Incidence of Contrast-induced Nephropathy
Renal damage due to contrast media (CM) administration is one of the main complications of cardiac intervention and is called contrast-induced nephropathy (CIN).
- Trial name
- NCT04225013
- Testing
- Early kidney damage biomarkers, Predisposition to kidney injury biomarkers
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- R. Laura Vicente Vicente
Contrast-induced Nephropathy
Coenzyme Q10 Role in Prevention of Contrast Induced Nephropathy in Acute Coronary Syndrome Patients.
In this study the investigators aim to study the effect of supplementation of CoQ10 in decreasing the incidence of contrast induced acute kidney injury in patients with acute coronary syndrome undergoing coronary angiography.
- Trial name
- NCT06429345
- Testing
- Coenzyme Q10 100 Milligrams Oral Capsule
- Where
- 2 sites in Egypt
- Volunteers
- 250 people
- Sponsor
- Ain Shams University