Clinical trials: Contact Lens Complication
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Pterygium of Both Eyes, Pain, Postoperative
The Two Most Common Ways Post-operative Eye Patch Are Therapeutic Contact Lenses (TCL) and Overnight Bandaging With Tight Bandage Patch: This Study is Designed to Determine the Most Effective Post-operative Care to Relief the Patient's Discomfort After Pterygium Excision Surgery
This study is designed to determine the most effective post-operative care to relief the patient's discomfort after pterygium excision surgery.
- Trial name
- NCT04151862
- Testing
- tight eye bandage, Soflex Soft Contact Lens
- Volunteers
- 50 people
- Sponsor
- Soroka University Medical Center
Contact Lens Complication, Astigmatism
Total30 for Astigmatism Contact Lenses
Determine if Total30 for Astigmatism contact lenses (CLs) provide a comfortable wearing experience all day. CL discomfort affects most CL wearers with discomfort consistently topping the reasons why established CL wearers drop…
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- NCT06052046
- Testing
- TOTAL30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Dry Eye, Contact Lens Complication
Dailies Total 1 Sphere Contact Lenses
CL discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society in their seminal report on contact lens (CL) discomfort as a condition that results in "episodic or persistent adverse ocular…
- Trial name
- NCT05239494
- Testing
- DT1 Sphere Contact Lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Contact Lens Complication
Observational Study on the Efficacy and Tolerance of EYEBRID Lenses
Technical advances in lenses are continuous and materials are improved. We provide a prospective longitudinal observational study evaluating the efficacy and safety of new EyeBrid Excel hybrid lenses (LCS) in the treatment of…
- Trial name
- EYEBRID (NCT05036954)
- Testing
- EyeBrid Excel hybrid lenses
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Caen
Ocular Discomfort, Ocular Inflammation
Effects of Xiidra on Closed Eye Tear Film Leukocytes in Dry Eye Disease
Every night during sleep, there is an accumulation of white blood cells in the closed eye. The closed eye white blood cells are predominantly neutrophils, but there is a small population (3%) of T cells.
- Conditions
- Ocular Discomfort, Ocular Inflammation, Dry Eye, Contact Lens Complication
- Trial name
- NCT03408015
- Testing
- Lifitegrast
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Myopia, Progressive, Children, Only
Myopia Control With Orthokeratology Contact Lenses in Spain
The purpose of this prospective study is to assess the efficacy, safety and patient-reported outcomes of the Menicon Z Night orthokeratolgy contact lens for reducing myopia progression in children.
- Conditions
- Myopia, Progressive, Children, Only, Contact Lens Complication, Perception, Self
- Trial name
- MCOS (NCT04806763)
- Testing
- Menicon Z Night, Control
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Menicon Co., Ltd.
Dry Eye, Contact Lens Complication
Treating Contact Lens Discomfort With Orthokeratology
The primary aim of this study is to understand if orthokeratology can be used to improve contact lens comfort and the secondary aim is understand patient adaptation to orthokeratology.
- Trial name
- NCT03566680
- Testing
- Orthokeratology
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dry Eye, Contact Lens Complication
Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens Users
In this study, two treatments typically used for dry eye disease will be tried for contact lens users to see if their symptoms when they use their contact lenses get better.
- Trial name
- CycliP (NCT06392438)
- Testing
- CycloSPORINE Ophthalmic, Intense Pulsed Light
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- Université de Sherbrooke
Contact Lens Complication
A Clinical Study Comparing the Comfort of Three Commercially Available Contact Lenses
The purpose of this study is to compare the comfort of three commercially available contact lenses.
- Trial name
- NCT02298400
- Testing
- Acuvue® Oasys® Lenses (senofilcon A), 30-Day Bausch + Lomb PureVision (balafilcon A), Clariti® 1-Day (Somofilcon A)
- Where
- United States
- Sponsor
- ORA, Inc.
Contact Lens Complication
Efficacy of "Aquoral Lipo" Artificial Tears in Contact Lens Wearers With Discomfort
There are more than 140 million contact lens wearers in the world. However, contact lens use can cause discomfort symptoms in up to 50% of wearers.
- Trial name
- NCT05290727
- Testing
- Aquoral Lipo (Esteve), Hyabak (Thea)
- Where
- Spain
- Volunteers
- 41 people
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Contact Lens Complication, Astigmatism
T30 for Astigmatism in Digital Device Users
This study aims to determine if Total30 lenses for astigmatism can be successfully fit in participants who are heavy digital device users.
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- T30FA (NCT06266728)
- Testing
- Total30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Contact Lens Complication, Debris in Post Lens Tear Reservoir
Evaluation of Contact Lens Saline Solutions With Scleral GP Contact Lens Wearers Experiencing Fogging
Evaluation of saline solutions used with scleral rigid gas permeable contact lens wearers experiencing debris in the post lens tear reservoir
- Trial name
- NCT03525704
- Testing
- Saline Solution Enriched, Saline Rinse Solution
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Contamac Ltd
Contact Lens Complication, Contact Lens Acute Red Eye
Soft Contacts Observation of Risk and Education (SCORE)
Specific Aims 1. Develop risk assessment scores for SCL wearers 2. Test the scoring algorithm in SCL wearers who present with adverse events 3. Explore targeted patient education to reduce risk behaviors associated with SCL wear.
- Conditions
- Contact Lens Complication, Contact Lens Acute Red Eye, Contact Lens Related Corneal Infiltrate (Disorder), Contact Lens-Induced Corneal Fluorescein Staining
- Trial name
- SCORE (NCT03305484)
- Testing
- No intervention
- Where
- 5 sites in United States, Canada
- Volunteers
- 171 people
- Sponsor
- Southern California College of Optometry at Marshall B. Ketchum University
Contact Lens Complication, Dry Eye
Total30 Sphere Contact Lenses
The purpose of this study is to map comfort over the full wear day in established, asymptomatic, soft CL wearers who are refit in Total30 Sphere CLs.
- Trial name
- NCT05183022
- Testing
- Total30 Sphere Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Contact Lens Complication, Small Incision Lenticule Extraction
Long-term Effects of SCL-wearing on Corneal Neuromediators and Postoperative Rehabilitation After SMILE
To investigate the effects of neuromediators in corneal stromal lenticules from patients with long-term soft contact lens (SCL) wear on corneal nerve regeneration and visual quality recovery following small incision lenticule…
- Trial name
- SCL SMILE (NCT07001306)
- Where
- China
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- yuhao shao
Contact Lens Complication
The Impact of Soft Contact Lenses on the Corneal Neuromediators and Optical Quality in High Myopia Prior to SMILE
To investigate the influence of Neuromediators expression in corneal stromal lenticules and corneal injury repair after small incision extraction
- Trial name
- NCT06650306
- Testing
- This study does not involve any interventions
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- yuhao shao
Dry Eye, Contact Lens Complication
Effects of Supplementation With PUFAs and Antioxidants for Contact Lens Discomfort
HydroEye® is a dietary omega 3 fatty acid supplement that contains both EPA and DHA, as well as GLA and ALA in the form of black currant seed oil.
- Trial name
- NCT04163328
- Testing
- HydroEye®
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye, Contact Lens Complication
Direct Application of Systane Complete to Contact Lenses
A common first line treatment for patients with dryness symptoms or contact lens discomfort is the application of artificial tears or rewetting drops, respectively.
- Trial name
- NCT03848221
- Testing
- Systane Complete, Sensitive Eyes Rewetting Drops
- Where
- 3 sites in United States
- Volunteers
- 73 people
- Sponsor
- University of Alabama at Birmingham
Dry Eye, Contact Lens Complication
Total30 For Contact Lens Dropouts
Contact lens (CL) discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society (TFOS) in their seminal report on CL discomfort as a condition that results in "episodic or persistent adverse…
- Conditions
- Dry Eye, Contact Lens Complication, Contact Lenses
- Trial name
- T30DO (NCT06967298)
- Testing
- T30 Contact lenses
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry