Clinical trials: Contact Lens Comfort
Astigmatism
Toric Contact Lens Digital Performance and Comfort Study
This study seeks to quantify digital visual performance and subjective visual acceptance of toric contact lenses as compared to spherical lenses in low to moderate astigmatic patients.
- Trial name
- NCT04772560
- Testing
- Precision1 for Astigmatism, Precision1 Sphere
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kathryn Richdale
Myopia
A Multi-Center Investigation of Patient Acceptability of OPTI-FREE RepleniSH® Multi-Purpose Disinfecting Solution (MPDS)
The purpose of this study was to demonstrate that current successful fulltime daily wear soft contact lens wearers using competitive multi-purpose solutions will note improved comfort when using OPTI-FREE RepleniSH®.
- Trial name
- NCT00772707
- Testing
- Multi-Purpose Disinfecting Solution (OPTI-FREE RepleniSH), Contact Lenses
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Contact Lens Comfort
Contact Lens Adaptation in Neophytes
Eye care professionals prescribe contact lenses to new wearers on a daily basis, and it is common practice for practitioners to educate their patients to gradually increase their contact lens wear time over their first few days…
- Trial name
- CLAN (NCT02148263)
- Testing
- senofilcon A
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Ocular Comfort
Evaluation of Comfort in Symptomatic Contact Lens Wearers
The purpose of this study is to evaluate the comfort of an ocular lubricant in symptomatic contact lens wearers. This study will be conducted in Canada.
- Trial name
- NCT04963543
- Testing
- FID123238
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- Alcon Research
Patient Comfort, Lens Cleanliness
Comfort and Cleaning Evaluation of Multipurpose Solutions in Contact Lens Patients
To compare patient comfort and overall lens cleanliness with consecutive use of two multipurpose lens solutions.
- Trial name
- NCT00519948
- Testing
- new MPS, opti-free express no rub MPS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Innovative Medical
Dry Eye
Evaluation of Comfort of Ocular Lubricants in Symptomatic Contact Lens Wearers
The purpose of this study is to evaluate the ocular comfort of 3 ocular lubricants and a comparator.
- Trial name
- NCT05741216
- Testing
- OTF Ocular Lubricant, Ocular Lubricant
- Where
- 3 sites in Australia, Canada
- Volunteers
- 36 people
- Sponsor
- Alcon Research
Contact Lens Complication, Astigmatism
Total30 for Astigmatism Contact Lenses
Determine if Total30 for Astigmatism contact lenses (CLs) provide a comfortable wearing experience all day. CL discomfort affects most CL wearers with discomfort consistently topping the reasons why established CL wearers drop…
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- NCT06052046
- Testing
- TOTAL30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Refractive Error
Fitting Children With Contact Lenses
The purpose of this three-month study is to compare the quality of life and ease of fit among children wearing investigational single-vision contact lenses, commercially marketed single-vision contact lenses, and commercially…
- Trial name
- COPPER (NCT01233089)
- Testing
- Lotrafilcon B contact lens, investigational, Lotrafilcon B contact lens, commercial (AIR OPTIX AQUA), Lotrafilcon B multifocal contact lens, commercial (AIR OPTIX AQUA MULTIFOCAL)
- Where
- Canada
- Volunteers
- 194 people
- Sponsor
- CIBA VISION
Dry Eye Syndromes, Meibomian Gland Dysfunction
The Effect of Tear Supplements on Contact Lens Comfort
The primary goal of this investigation is to determine if lipid based artificial tear supplementation has an impact on contact lens discomfort (CLD).
- Trial name
- NCT02956083
- Testing
- Systane Balance eye drops, Systane Contacts eye drops, saline
- Volunteers
- 30 people
- Sponsor
- University of the Incarnate Word
Contact Lens Comfort and Successful Refitting
How Does DT1 Sphere Perform in Current and Successful Acuvue MAX Wearers?
The goal of this prospective study is to to understand if satisfied MAX Contact lens (CL)wearers can be successfully refit into Dailies total 1 (DT1) CL in healthy MAX CL wearers between the ages of 18-40.
- Trial name
- NCT06847230
- Testing
- Dailies total 1 contact lenses
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Contact Lens Solution Toxicity
Assessing Patient Comfort With Two Different Multi-Purpose Disinfecting Solutions
Tolerability is compared between two Multi-purpose disinfecting solutions (MPDS).
- Trial name
- NCT01847105
- Testing
- RevitaLens, OptiFree PureMoist
- Where
- 3 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Hom, Milton M., OD, FAAO
Contact Lens Base Curve (BC) Fit and Comfort
Evaluation of 8.5 vs 9.0 Base Curve for 1-DAY ACUVUE(r) TruEye(r) Brand Contact Lenses
The objective of this study is to determine if corneal diameter and keratometry readings correlate to subjective comfort and lens fitting characteristics.
- Trial name
- NCT02537522
- Testing
- Contact Lenses with 8.5 BC, Contact Lenses with 9.0 BC
- Where
- 2 sites in United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Refractive Error
Multi-Center Clinical Evaluation of Two Daily Disposable Contact Lenses (Study 2)
The purpose of this study is to compare the subjective performance of two daily disposable contact lenses with respect to comfort and handling.
- Trial name
- NCT01917162
- Testing
- Nelfilcon A contact lens, UltraFilcon B contact lens
- Where
- United Kingdom
- Volunteers
- 86 people
- Sponsor
- Alcon Research
Myopia, Astigmatism
Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers
The purpose of this study was to assess the comfort of OPTI-FREE RepleniSH in soft contact lens wearers.
- Conditions
- Myopia, Astigmatism, Refractive Error
- Trial name
- NCT01211535
- Testing
- OPTI-FREE RepleniSH multipurpose solution, ReNu Biotrue multipurpose solution, Silicone hydrogel contact lenses
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- Alcon Research
Contact Lens Related Dry Eye
The Impact of Hypo-osmolar Drops on Contact Lens Comfort
This pilot study will investigate the impact of sterile saline drops that are formulated at hypo-osmolar levels on CL comfort in comparison to an iso-osmolar drop, in a group of symptomatic CL wearers.
- Trial name
- SAFFRON (NCT03050125)
- Testing
- Hypo-osmolar drop 1, Hypo-osmolar drop 2, Iso-osmolar drop
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre for Contact Lens Research
Ametropia
Comparison of Two Toric Contact Lenses on Current Toric Wearers
The purpose of this study is to evaluate and compare the clinical performance of two toric contact lenses amongst 110 subjects, 2-week, single masked (subject), daily wear, randomized, bilateral, crossover study; 4 weeks…
- Trial name
- NCT00639379
- Testing
- senofilcon A toric, alphafilcon A toric
- Where
- 7 sites in United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Meibomian Gland Dysfunction
Contact Lens Comfort Relative to Meibomian Gland Status
This trial aims to establish a correlation between patient reported comfort while using soft contact lenses and meibomian gland dysfunction (MGD).
- Trial name
- NCT01819194
- Testing
- senofilcon A
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Vision Care, Inc.
Contact Lens Comfort and Successful Refitting, Presbyopia
Refitting Satisfied INFUSE One-Day Multifocal Wearers to DAILIES TOTAL1 Multifocal Contact Lenses
The purpose of this study is to determine the comfort and vision of DAILIES TOTAL1 Multifocal contact lenses in a population of satisfied INFUSE One-Day Multifocal contact lens wearers
- Trial name
- INFUSETODT1 (NCT07638943)
- Testing
- DAILIES TOTAL1 Multifocal (delefilcon A)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gordon Schanzlin New Vision
Dry Eye, Contact Lens Complication
Dailies Total 1 Sphere Contact Lenses
CL discomfort is a complex phenomenon that has been defined by the Tear Film and Ocular Surface Society in their seminal report on contact lens (CL) discomfort as a condition that results in "episodic or persistent adverse ocular…
- Trial name
- NCT05239494
- Testing
- DT1 Sphere Contact Lenses
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Myopia
A Prospective Study of Two Daily Disposable Contact Lenses
The purpose of this study was to evaluate the performance of a novel silicone hydrogel contact lens, DAILIES TOTAL1® (DT1) compared to the standard hydrogel material in 1-DAY ACUVUE® MOIST® (1DAVM) contact lens in contact lens…
- Trial name
- NCT01636986
- Testing
- Delefilcon A contact lenses, Etafilcon A contact lenses
- Volunteers
- 62 people
- Sponsor
- Alcon Research