Clinical trials: Congenital Cataract
Glaucoma, Congenital Cataract
Glaucoma After Congenital And Infantile Cataract Surgery
Pediatric patients who have undergone surgery for congenital or infantile cataracts have a risk of developing suspected glaucoma and glaucoma, but the current evidence does not address our understanding of the incidence and…
- Trial name
- NCT04131114
- Where
- China
- Volunteers
- 241 people
- Sponsor
- Sun Yat-sen University
Cataract, Fuchs Endothelial Corneal Dystrophy
Partial Range Of Field IOLs in DMEK-Enabled Procedures
Study Overview This study aims to evaluate the visual outcomes, quality of vision, and patient satisfaction after receiving an extended range PRoF intraocular lens (IOL) during triple Descemet Membrane Endothelial Keratoplasty…
- Trial name
- PROFIDE (NCT07441616)
- Testing
- combined cataract and lamellar endothelial keratoplasty
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Universitair Ziekenhuis Brussel
Congenital Cataract, Aphakic or Pseudophakic Glaucoma
Mechanism of Aphakic and Pseudophakic Glaucoma in Pediatric Patients
In cell cultures, lens epithelial cells and trabecular meshwork cells will be exposed to aqueous humor from pediatric eyes undergoing cataract removal surgery.
- Trial name
- NCT01136473
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Carmel Medical Center
Cataract
Developmental Profile of Ocular Refraction in Patients With Congenital Cataract
The purpose of prospective cohort study is to describe the developmental profile of refraction change in a large cohort of Chinese CC patients.
- Trial name
- NCT02761850
- Where
- China
- Volunteers
- 1,164 people
- Sponsor
- Sun Yat-sen University
Cataract
Effect of the Timing of Cataract Surgery on Complications in Patients With Bilateral Congenital Cataracts
Congenital cataract is an important treatable cause of visual handicap in childhood throughout the world. Successful management of childhood cataract is dependent on individualized treatment strategies and rigorous postoperative…
- Trial name
- NCT02581046
- Testing
- Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 3month of the patients, Phacomulsification lens removal cataract surgery without Intraocular lens(IOL) implantation at the age of 6 month of the patients, Subconjunctival dexamethasone and general anesthesia
- Where
- China
- Volunteers
- 61 people
- Sponsor
- Sun Yat-sen University
Congenital Cataract
The Effect of Ophthalmic Solutions on Contact Lenses Used After Surgery for Congenital Cataract Investigated in Vivo
Patients with congenital cataract operated at St. Erik Eye Hospital are given the topical steroid dexamethasone (Isopto-Maxidex) according to a set treatment plan.
- Trial name
- NCT03125785
- Volunteers
- 80 people
- Sponsor
- St. Erik Eye Hospital
Aphakia
Artisan Aphakia Lens for the Correction of Aphakia in Children
The purpose of this study is to determine the safety and effectiveness of the Artisan Aphakia Lens in the treatment of aphakia in children.
- Trial name
- NCT01547442
- Testing
- Artisan Aphakia Intraocular Lens
- Where
- 19 sites in United States, Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ophtec USA
Cataract
Comparison of Artificial Intelligent Clinic and Normal Clinic
In this study, the investigators provide participants≤14 years old the artificial intelligent clinic or normal clinic in the purpose of seeking out a better way to make a definite diagnosis with high efficiency and accuracy, and…
- Trial name
- NCT03240848
- Testing
- artificial intelligent clinic, normal clinic, experts diagnose
- Where
- China
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Fuch's Endothelial Dystrophy, Cataracts
Study of the Effect of Aspheric Lenses in Patients With Fuch's Dystrophy
The proposed study will recruit patients with mild to moderate Fuch's dystrophy who need cataract surgery alone. They will be randomly assigned to receive either spheric or aspheric lenses.
- Trial name
- NCT02109276
- Testing
- Spheric Sensar(R) 3-piece IOL, Aspheric Tecnis(R) 3-piece IOL
- Where
- Canada
- Sponsor
- Queen's University
Congenital Cataract
Clinical Characteristics in Congenital Cataract Eyes
This study involved children with congenial cataract eyes, who underwent cataract surgeries at the Eye Hospital of Wenzhou Medical University (Hangzhou, China). All medical records were reviewed for primary diagnosis.
- Trial name
- NCT03905044
- Testing
- eyes with congenital cataracts
- Volunteers
- 239 people
- Sponsor
- yin ying zhao
Cataract
Individual vs Cohort Long Distance Advising for Mental Care for Congenital Cataract Guardians
Nowadays, doctors put mental health at a prior place and pay more attention to the psychological problems of ill kids' parents. In our research, we try to find a new modern and efficient psychological counseling mode to improve…
- Trial name
- NCT03216655
- Testing
- phone call, wechat group
- Where
- China
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Cataract, Down Syndrome
Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome
This study involves the collection ocular lens tissue from individuals with Down syndrome and age-matched controls at the time of cataract surgery.
- Trial name
- NCT03778528
- Testing
- cataract surgery
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Colorado, Denver
Congenital Cataract
Comparison of Minimal Invasive Lens Surgery and Traditional Cataract Surgery
Previously, we have developed a minimal invasive lens surgery in the purpose of reduce post-operative complications of congenital cataract.
- Trial name
- NCT03230799
- Testing
- minimal invasive lens surgery, traditional cataract surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sun Yat-sen University
Congenital Cataract, Aphakic Glaucoma
Prophylactic Peripheral Iridectomy Prevents Aphakic Angle-closure Glaucoma
This is a retrospective, nonrandomized comparative trial with historical control to investigate the safety and efficacy of a novel progressive grasping peripheral iridectomy (PGPI) surgical method in preventing aphakic…
- Trial name
- NCT03610295
- Testing
- PPI group, cataract extraction
- Where
- 2 sites in China
- Volunteers
- 87 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Congenital Cataract
Reduction of Corneal Astigmatism With Toric Intraocular Lens Implantation in Congenital Cataract
This study was conducted to evaluate changes of reduction of corneal astigmatism with toric intraocular lens(IOL) in congenital cataract.
- Trial name
- NCT02040129
- Testing
- Acrysof Toric IOL
- Where
- South Korea
- Volunteers
- 4 people
- Sponsor
- Kyungpook National University Hospital
Fuchs' Endothelial Dystrophy, Cataract
Netarsudil Use After Descemetorhexis Without Endothelial Keratoplasty
Primary aim of the study is to determine whether a rho kinase inhibitor, Netarsudil, can speed corneal clearance after DWEK. Secondary aim of the study is to investigate whether patient factors, such as baseline age, pachymetry…
- Trial name
- NCT04057053
- Testing
- Netarsudil 0.02% Ophthalmic Solution
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts Eye and Ear Infirmary
Cataract
Clinical and Genetic Studies of Families With Congenital or Hereditary Cataracts
This study will explore the clinical and hereditary (genetic) features of inherited cataracts. A cataract is a clouding of the eye lens, which focuses light on the back of the eye.
- Trial name
- NCT00056771
- Where
- 5 sites in United States, China and 3 more
- Volunteers
- 3,432 people
- Sponsor
- National Eye Institute (NEI)
Leukodystrophy, White Matter Disease
LeukoSEQ: Whole Genome Sequencing as a First-Line Diagnostic Tool for Leukodystrophies
Leukodystrophies, and other heritable disorders of the white matter of the brain, were previously resistant to genetic characterization, largely due to the extreme genetic heterogeneity of molecular causes.
- Conditions
- Leukodystrophy, White Matter Disease, 4H Syndrome, Adrenoleukodystrophy
- Trial name
- NCT02699190
- Where
- United States
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Philadelphia
Deprivation Amblyopia, Congenital Cataract
Augmented Reality Training for Amblyopia After Congenital Cataract Surgery
This study will evaluate whether augmented reality training is effective and safe for treating unilateral amblyopia after congenital cataract surgery in children.
- Trial name
- NCT07693790
- Testing
- Augmented Reality Amblyopia Training, Conventional Patching
- Volunteers
- 88 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract Congenital
Multifocal vs Monofocal IOL in Congenital Cataract Surgery
The aim of this study is to evaluate long-term outcome after congenital cataract surgery comparing results achieved with multifocal and monofocal IOLs.
- Trial name
- NCT04872829
- Testing
- cataract surgery
- Volunteers
- 43 people
- Sponsor
- Bambino Gesù Hospital and Research Institute