Clinical trials: Complication Rate, active
Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD)
Relationship Between Insulin Dose and Complications in Type 1 Diabetes
The goal of this observational study is to better understand how the amount of insulin people with type 1 diabetes are using relates to blood glucose control and the risk of complications.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD), Severe Albuminuria, Estimated Glomerular Filtration Rate (eGFR)
- Trial name
- iDose-EDC (NCT07911033)
- Testing
- Routine/prescribed exogenous insulin dose
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rachel Miller
Mechanical Ventilation Complication, Ventilator Induced Lung Injury
Mechanical Power and Mortality in Mechanically Ventilated Adults
This prospective observational cohort study aims to investigate the relationship between mechanical power during the first 72 hours of invasive mechanical ventilation and 28-day mortality in mechanically ventilated adult patients…
- Conditions
- Mechanical Ventilation Complication, Ventilator Induced Lung Injury, ARDS, ICU Mortality (Survival Rate)
- Trial name
- NCT07836153
- Where
- Egypt
- Volunteers
- 116 people
- Sponsor
- Zagazig University
Heart Rate Monitoring, Vagal Bradycardia
Heart Rate Variability and Early Cytokine Profile in Pediatric Adenotonsillectomy
This prospective observational cohort study will assess whether perioperative short-term heart rate variability (HRV) indices and early inflammatory cytokine levels are associated with respiratory and cardiac adverse events in…
- Conditions
- Heart Rate Monitoring, Vagal Bradycardia, Adenotonsillar Hypertrophy, Tonsillitis; Hypertrophic
- Trial name
- NCT07719439
- Where
- Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Duzce University
Diabetes, Surgery Related Complications Rate
Preoperative Optimization of Diabetic Patients
Diabetic patients, as part of preoperative evaluation, should have glycated hemoglobin (HbA1C) measured. HbA1C provides information on longterm glucose control.
- Trial name
- NCT06589466
- Testing
- Surgery
- Where
- Canada
- Volunteers
- 46,000 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Complication Rate, Efficacy and Safety
Efficacy of Thermal Ablation Combined With Antithyroid Drugs in the Treatment of Primary Hyperthyroidism
Hyperthyroidism is a clinical syndrome caused by excessive production of thyroid hormones, leading to accelerated metabolism and increased excitability of multiple organ systems.
- Conditions
- Complication Rate, Efficacy and Safety, Hyperthyroidism/Thyrotoxicosis, Cure Rate
- Trial name
- NCT07557810
- Testing
- thermal ablation combined with antithyroid drug therapy
- Where
- China
- Volunteers
- 454 people
- Sponsor
- Chinese PLA General Hospital
Frailty in Adult Surgery, Frailty Syndrome
Modified Essential Frailty Toolset in Older Adults Undergoing Major Elective Surgery
Frailty is a common geriatric syndrome associated with reduced physiological reserve and increased vulnerability to surgical stress.
- Conditions
- Frailty in Adult Surgery, Frailty Syndrome, Elective Surgeries, Readmission Rates
- Trial name
- NCT07452263
- Testing
- Major elective surgery
- Where
- Iceland
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Iceland
Acute Pancreatitis, Complication
Rectal Indomethacin as Early Treatment for Acute Pancreatitis (INDOMAP Trial)
Acute pancreatitis (AP) is an inflammatory condition of the pancreas following the activated pancreatic enzymes induced by varied causes, with or without other organ(s) dysfunction.
- Conditions
- Acute Pancreatitis, Complication, Mortality Rate, Organ Failure, Multiple
- Trial name
- INDOMAP (NCT03547232)
- Testing
- Indomethacin SR
- Where
- 17 sites in China
- Volunteers
- 1,504 people
- Sponsor
- Peking Union Medical College Hospital
Microtia, Outcome Assessment
Safety and Efficacy of Connecting the Residual Ear to the Cartilage Scaffold in First- vs. Second-Stage Surgery
Eligible patients will be admitted from the outpatient clinic to complete the relevant examinations after admission（Preoperative routine examination and chest CT）.
- Conditions
- Microtia, Outcome Assessment, RCT, Surgery Related Complications Rate
- Trial name
- NCT06763991
- Testing
- Two-stage connection, One-stage connection
- Where
- China
- Volunteers
- 78 people
- Sponsor
- Sichuan Provincial People's Hospital
Cure Rate, Complication Rate
Thermal Ablation Versus Parathyroidectomy for Primary Hyperparathyroidism
This study is a prospective, multicenter study designed to compare the efficacy and safety of surgical treatment versus ablation therapy (including radiofrequency ablation and microwave ablation) for patients with primary…
- Conditions
- Cure Rate, Complication Rate, Efficacy and Safety
- Trial name
- NCT06708871
- Testing
- Thermal ablation, Parathyroidectomy
- Volunteers
- 520 people
- Sponsor
- Chinese PLA General Hospital
IBD (Inflammatory Bowel Disease), Hemorrhoid
HEmorrhoidAl Disease in Inflammatory Bowel Disease: a Multicenter Prospective Cohort Study
Patients who will undergo surgery for HD after the diagnosis of IBD over a 12-month period will be enrolled across Europe. Primary objective of this study is to determine the safety and effectiveness of surgical treatments for HD…
- Conditions
- IBD (Inflammatory Bowel Disease), Hemorrhoid, Safety, Sugery
- Trial name
- HEAD-IBD-II (NCT06638814)
- Volunteers
- 50 people
- Sponsor
- Treviso Regional Hospital