Clinical trials: Complex Post-Traumatic Stress Disorder
Bipolar Disorder, Posttraumatic Stress Disorder
Study to Promote Innovation in Rural Integrated Telepsychiatry
Background: Community Health Centers care for over 20 million rural, low income and minority Americans every year. Patients often have complex mental health problems such as Posttraumatic Stress Disorder (PTSD) and Bipolar…
- Trial name
- SPIRIT (NCT02738944)
- Testing
- Telepsychiatry Collaborative Care, Telepsychiatry Enhanced Referral
- Where
- 13 sites in United States
- Volunteers
- 1,004 people
- Sponsor
- University of Washington
CPTSD, Compelx Post-traumatic Stress Disorder
The Effectiveness of Guided Written Exposure Therapy for Complex PTSD in Adolescents
This study aims to examine the effectiveness of group Guided Written Exposure Therapy for Complex Post-Traumatic Stress Disorder (GWE-C) among Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT07325734
- Testing
- Group Guided Written Exposure Therapy for CPTSD (GWE-C), Supportive Group
- Where
- 4 sites in China
- Volunteers
- 130 people
- Sponsor
- Peking University
Complex Post-Traumatic Stress Disorder (CPTSD), Post-traumatic Stress Disorder (PTSD)
Prevalence of Complex PTSD in Trauma-Exposed Children-Adolescents and Related Factors
The aim of this study is to assess the psychiatric evaluation of children and adolescents exposed to trauma in the outpatient clinic and to determine the prevalence of PTSD and Complex PTSD (CPTSD) diagnoses.
- Trial name
- NCT06918899
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University
Non Suicidal Self Injury
The Effect of Intravenous Ketamine on Non Suicidal Self Injuries.
Non-suicidal self-injuries (NSSI) is a deliberate harm a person causes directly to their body, resulting in structural or functional damage, without suicidal ideation.
- Trial name
- NCT04242914
- Testing
- Ketamine, Midazolam
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Post-Traumatic Stress Disorder Complex, Emotional Dysregulation
Child-Parent Psychotherapy After the 2023 Kahramanmaraş Earthquake
This study aims to evaluate the effectiveness of Child-Parent Psychotherapy (CPP) in reducing trauma-related symptoms and improving attachment quality among preschool-aged children who experienced the 2023 Kahramanmaraş…
- Trial name
- NCT07040462
- Testing
- Child-Parent Psychotherapy (CPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beykoz University
Complex Post-Traumatic Stress Disorder (CPTSD)
RECONNECT - Treatments for Complex PTSD
Complex PTSD (CPTSD) is a new diagnosis for which no established gold-standard treatment(s) yet exists. In this trial, three psychotherapies, Prolonged Exposure (PE), Eye Movement Desensitization and Reprocessing (EMDR), and…
- Trial name
- NCT07863089
- Testing
- Prolonged Exposure, EMDR, ESTAIR
- Volunteers
- 225 people
- Sponsor
- University of Copenhagen
Complex Post-Traumatic Stress Disorder
Eye Movement Desensitization and Reprocessing (EMDR) in Complex Psychotrauma
This study wants to demonstrate the effectiveness of combining a positive memory with "recommended" therapy based on EMDR in reducing the disturbance that patients with complex psychotrauma may experience.
- Trial name
- NCT04594434
- Testing
- Scale SUD, VOC scale, DES II scale
- Where
- France
- Volunteers
- 49 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Posttraumatic Stress Disorder, Dissociative Identity Disorder
Stabilizing Group Treatment of Complex Trauma: A Randomized Controlled Trial
The research project outlined in this proposal aims to investigate the effectiveness of stabilizing group treatment as an add-on to conventional treatment, for patients with Post Traumatic Stress Disorder (PTSD) or dissociative…
- Conditions
- Posttraumatic Stress Disorder, Dissociative Identity Disorder, Dissociative Disorder
- Trial name
- STAB (NCT02450617)
- Testing
- Conventional individual treatment, Stabilizing group treatment for PTSD, Stabilizing group treatment for Dissociative disorders
- Where
- Norway
- Volunteers
- 158 people
- Sponsor
- Modum Bad
PTSD, Addiction
The Course and Outcome of Integreated Trauma and Addiction Treatment Between PTSD and CPTSD
In the ICD-11 post-traumatic stress disorder (PTSD) and complex PTSD (CPTSD) are distinguished. CPTSD is associated with early childhood traumatization and more severe symptom patterns.
- Trial name
- NCT06588309
- Testing
- Eye movement desensitization and reprocessing (EMDR), CRA
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IrisZorg
Safety, Psychological, Acceptability of Health Care
Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms
This Pilot Randomized Controlled Trial (RCT) overall aim is to establish the safety, feasibility, acceptability and preliminary effects of a body-oriented psychotherapy, Somatic Experiencing (SE), on social functioning and mental…
- Conditions
- Safety, Psychological, Acceptability of Health Care, Psychological Safety, Maltreatment, Child
- Trial name
- NCT06549777
- Testing
- SE-group, Control
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Monique Pfaltz
Insomnia
Ramelteon for Complex Insomnia in Veterans With PTSD
Obstructive sleep apnea is commonly reported in Veterans with post-traumatic stress disorder, which can potentiate symptoms of anxiety and depression, daytime symptoms and worsen nightmares.
- Trial name
- DORMI (NCT03265951)
- Testing
- Ramelteon, Usual Care
- Where
- United States
- Sponsor
- State University of New York at Buffalo
Post-Traumatic Stress Disorder Complex, Psychiatric Disorder
Evaluation of the Efficacy of "Lifespan Integration" (LI) Therapy in Patients With Complex Post-Traumatic Stress Disorder
The study aims to evaluate the efficacy of a relatively new type of psychotherapy called Lifespan Integration (LI) in patients suffering of complex PTSD
- Conditions
- Post-Traumatic Stress Disorder Complex, Psychiatric Disorder, Abuse Neglect, Abuse Physical
- Trial name
- EVALI (NCT06535243)
- Testing
- Lifespan Integration Therapy (LI)
- Where
- France
- Volunteers
- 38 people
- Sponsor
- Centre Hospitalier St Anne
PTSD
The Effectiveness of Group-Delivered Guided Written Exposure Therapy for PTSD and CPTSD Among Chinese Adolescents
The study aims to examine the effectiveness of the group-delivered guided written exposure therapy (GWE) for post-traumatic stress disorder (PTSD) and complex PTSD among Chinese adolescents with a randomized controlled trial.
- Trial name
- NCT06390293
- Testing
- Group-delivered guided written exposure therapy, Waiting-List (WL) condition
- Where
- China
- Volunteers
- 53 people
- Sponsor
- Peking University
Anxiety Disorders, Complex Regional Pain Syndrome Type II
Regional Anesthesia Military Battlefield Pain Outcomes Study
The purpose of this study is to examine the short and long-term benefits of implementing early regional anesthesia techniques for pain control after a major traumatic injury to one or more extremities during combat in the…
- Conditions
- Anxiety Disorders, Complex Regional Pain Syndrome Type II, Depressive Disorders, Post-Traumatic Stress Disorder
- Trial name
- RAMBPOS (NCT00431847)
- Testing
- Regional Anesthesia, Standard Pain Management Protocol
- Where
- 3 sites in United States
- Volunteers
- 386 people
- Sponsor
- VA Office of Research and Development
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Trauma, Mental Health Disorder
Investigating the Effect of Evidence-based Treatment for Post-traumatic Stress Disorder Among Youth
Trauma-focused cognitive-behavioral therapy (TF-CBT) is an evidence-based practice (EBP) for the treatment of posttraumatic stress disorder (PTSD) and posttraumatic stress symptoms (PTSS) among children and adolescents.
- Conditions
- Trauma, Mental Health Disorder, PTSD, Implementation
- Trial name
- NCT05226481
- Testing
- Trauma-focused cognitive behavioral therapy (TF-CBT)
- Where
- Norway
- Volunteers
- 216 people
- Sponsor
- Norwegian Center for Violence and Traumatic Stress Studies
Post-traumatic Stress Disorder (PTSD), Complex Post-Traumatic Stress Disorder (CPTSD)
Two-Year Follow-up Study on Children Exposed to Trauma
In our clinic, we plan to conduct research two years after the initial assessments (January-April 2024 and one year ago, January-June 2025) of children and adolescents with trauma exposure who were evaluated as part of their…
- Trial name
- Complex PTSD (NCT07697534)
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Istanbul University
Posttraumatic Stress Disorder, Complex Post-Traumatic Stress Disorder
Using Data Science To Center Patient Perspectives in Mechanism Discovery
Including patient perspectives when developing new therapy interventions is crucial because it can help to understand response heterogeneity and promote engagement.
- Trial name
- CPP (NCT06233968)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Complex Post-Traumatic Stress Disorder
Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study
Modular Patient Centred CBT (MPC) for Complex PTSD (CPTSD) is a manualized psychotherapy programme that consists of five treatment modules addressing 1) Affect dysregulation, 2) Disturbed relationships, 3) Negative self-concept…
- Trial name
- PACE pilot RCT (NCT05259592)
- Testing
- Psychotherapy
- Where
- 5 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Veterans Centre
Post Traumatic Stress Disorder, Complex Post-Traumatic Stress Disorder
A Pilot Study of Trauma-Focused Cognitive-Behavioral Therapy for Treatment of Post-traumatic Stress in Adults.
Post-traumatic stress disorder (PTSD) is a mental health condition that's triggered by the experience of potentially traumatic events.
- Trial name
- NCT06516874
- Testing
- Trauma-Focused Cognitive Behavioral Therapy for complex presentation (TF-CBT-CP)
- Where
- 5 sites in Chile
- Volunteers
- 13 people
- Sponsor
- University of Talca