Clinical trials: Complex Medical Patients
Delivery of Health Care, Health Services
The COPACC Study: Utilization, Health and Economic Evaluation of a Community-Based Primary Care Geriatric Hub at Whampoa
This study evaluates the Community for Successful Ageing (ComSA) Patient-Centered Medical Home (PCMH), a model of community-based primary care geriatric hub at Whampoa, Singapore.
- Conditions
- Delivery of Health Care, Health Services, Costs and Cost Analysis, Quality of Life
- Trial name
- NCT04594967
- Testing
- Patient-centred care home (PCMH)
- Where
- Singapore
- Volunteers
- 184 people
- Sponsor
- Geriatric Education and Research Institute
Medically Complex Infants
Effects of Medical Complexity Using GMA on Lurie Children's In- and Outpatients
The purpose of this study is to research a new type of test for cerebral palsy that can be performed earlier, at 10-15 weeks of age (after the due date for premature infants).
- Trial name
- CIMA (NCT01659710)
- Where
- United States
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- Raye Ann deRegnier
Tuberous Sclerosis, Lymphangioleiomyomatosis
Characterization of Patients With Tuberous Sclerosis Complex, Lymphangioleiomyomatosis and Angiomyolipoma
Tuberous Sclerosis Complex (TSC) is a multisystemic autosomal dominant disease that is characterized by the development of benign neoplasms in brain, kidney, lung, skin and heart.
- Conditions
- Tuberous Sclerosis, Lymphangioleiomyomatosis, Angiomyolipoma
- Trial name
- NCT02325505
- Where
- 3 sites in Brazil
- Volunteers
- 200 people
- Sponsor
- InCor Heart Institute
Dental Phobia, Disabilities Multiple
Evaluation of Implant Therapies Performed Under General Anesthesia in Patients With Specific Dental Needs
Implant placement is the solution of choice for replacing missing teeth in a fixed way. However, dental practitioners and surgeons are reluctant to place implants in the population of patients with special needs.
- Conditions
- Dental Phobia, Disabilities Multiple, Complex Medical Health Condition
- Trial name
- NCT05153538
- Where
- France
- Volunteers
- 57 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Kidney Diseases
Prevalance Of Helicobacter Pylori Infection In Chonic Kidney Diseased Patient Admitted To Luxor Medical Complex
Detect prevalence of Helicobacter pylori infection in chronic kidney diseased patient admitted to Luxor medical complex and possible role of Helicobacter pylori in pathogenesis of chronic kidney diseased patient of unknown…
- Trial name
- NCT06371001
- Testing
- disease
- Volunteers
- 122 people
- Sponsor
- Assiut University
Polypharmacy, Inappropriate Prescribing
SPIDER: A Research & QI Collaboration Supporting Practices in Improving Care for Complex Elderly Patients
Elders living with multiple chronic conditions often take many drugs (polypharmacy); some of the drugs may not benefit them or may be harmful.
- Conditions
- Polypharmacy, Inappropriate Prescribing, Aged, Primary Health Care
- Trial name
- SPIDER (NCT03689049)
- Testing
- SPIDER, Usual Care
- Where
- 9 sites in Canada
- Volunteers
- 104 people
- Sponsor
- University of Toronto Practice Based Research Network
Opioid Dependence, Substance Abuse Disorders
The MOUD Plus Pilot: Counseling and Peer Support to Support Retention for Medically Complex Patients With Opioid Use Disorder Seen In Primary Care
The goal of this pilot clinical trial is to learn if a community informed designed program of addiction counseling with coordinated community peer navigator for people with Opioid Use Disorder (OUD) and other medical conditions…
- Conditions
- Opioid Dependence, Substance Abuse Disorders, Complex Medical Patients, Primary Care Patients With Chronic Conditions
- Trial name
- MOUD+ (NCT06837662)
- Testing
- MOUD "Plus" Intervention (treatment as usual + coordinated counseling and referral to community based peer), Treatment As Usual (primary care with low threshold MOUD prescribing)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Automated Communication Tools, Complex Medical Patients
Virtual Continuity and Its Impact on Complex Hospitalized Patients' Care
Communication between physicians caring for a patient in the hospital and that patient's primary care provider is less than optimal, and can lead to diminished health care quality and safety.
- Trial name
- NCT01397253
- Testing
- Automated communication tools
- Where
- United States
- Volunteers
- 835 people
- Sponsor
- University of Pittsburgh
Trauma
Identification of Post-Traumatic Stress Disorder in Adult Patients With Substance Use Disorders
The aim of this study is to show that early identification of PTSD and CPTSD would increase recognition of these disorders and facilitate diagnosis, referral and recovery.
- Trial name
- IRTIPAP (NCT06432400)
- Testing
- Patient questionnaires
- Where
- 2 sites in France
- Sponsor
- Hôpital NOVO
Post-traumatic Stress Symptoms, Anxiety
Psychological Prehabilitation for Complex Gastrointestinal Surgery
The goal of this clinical trial is to learn if a psychological program before surgery can help adults who have lasting stress from past medical experiences. The program is called PREPARE-GI.
- Conditions
- Post-traumatic Stress Symptoms, Anxiety, Depression Disorder, Gastrointestinal Disease
- Trial name
- PREPARE-GI (NCT07865052)
- Testing
- PREPARE-GI
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Northwestern University
Pediatric Medical Complexity Based on PMCA Score of 3
Comprehensive Assessment of Reactions to Pharmacogenetics in Complex Care Patients
The goal of this clinical trial is to determine the feasibility and acceptability of Pharmacogenetic Testing, and the attitudes towards the same in caregivers of complex care patients in Cincinnati, OH.
- Trial name
- CAREPICC (NCT07060300)
- Testing
- Agree to Pharmacogenetic Testing
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Diabetes Mellitus, Type 2
Pre-Visit Prioritization for Complex Patients With Diabetes
Patients with type 2 diabetes are increasingly complex. Lack of time to address all patient and provider priorities during primary care visits represents a barrier to effective primary care.
- Trial name
- PVP (NCT02375932)
- Testing
- Pre-Visit Tool, Usual Care Control
- Volunteers
- 146 people
- Sponsor
- Kaiser Permanente
Thymoma
Efficacy of Octreotide Treatment in Patients With Primary Inoperable Thymoma
This study will investigate the efficacy of treatment with octroetide in patients with primary inoperable thymoma to reduce tumor size.
- Trial name
- NCT00332969
- Testing
- Octreotide
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Novartis Pharmaceuticals
Acute Bleeding on Long-Term Anticoagulation Therapy, Hemorrhage
Fixed Versus Variable Dosing of 4-factor Prothrombin Complex Concentrate for Emergent Warfarin Reversal
The goal of this study is to determine if a fixed dose of 4-factor prothrombin complex concentrate (4FPCC) is as effective as the current standard of care.
- Conditions
- Acute Bleeding on Long-Term Anticoagulation Therapy, Hemorrhage, Significant Bleeding in Patients With a Coagulopathy (Prolonged Thrombin Time), Urgent Reversal of Vitamin K Antagonist (VKA) Anticoagulation
- Trial name
- kcentra (NCT03064035)
- Testing
- 4-factor prothrombin complex concentrate (4FPCC)
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- HealthPartners Institute
Intellectual Disability, Variable
A Pilot Project to Facilitate Dental Care and Reduce Barriers For Youth With Disabilities
This randomized clinical trial is an innovative pilot project to determine the acceptance and impact of telehealth visits on youth with intellectual and developmental disabilities (IDD), their caregivers, and dentists.
- Trial name
- NCT06710483
- Testing
- Pre-Dental Telehealth (PDT)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Boston University
Pediatrics, Medically Complex
Parental Adherence of a Mobile Application
This is a single-site, stratified grouping parallel- randomized control trial design comparing 30-day all-cause readmission rates and parent experience with two groups of pediatric participants.
- Conditions
- Pediatrics, Medically Complex, Children With Medical Complexity (CMC), Nursing
- Trial name
- PARAMETER (NCT06672042)
- Testing
- CHAMP App
- Where
- United States
- Sponsor
- Children's Mercy Hospital Kansas City
Geriatric Disorder, Mobil Unit
Provision of a Mobile Geriatric Team Extra-Community Hospital
The purpose of this study is to demonstrate the effectiveness of the mobile unit to reduce the geriatric hospital inappropriate (especially for emergencies) to 1 month.
- Trial name
- UMG (NCT01449968)
- Testing
- home visit, telephone management
- Where
- 3 sites in France
- Volunteers
- 334 people
- Sponsor
- University Hospital, Grenoble
Multiple Co-morbidities
Computer Assisted Symptom Evaluation of Complex Patients
Patients who have advanced or multiple chronic illnesses present management difficulties for primary care providers. Acute medical issues and limited time for patient evaluation can complicate complete assessment of physical…
- Trial name
- CASE (NCT01391026)
- Testing
- Enhanced patient-centered care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Cook County Health
Women With Breast Cancer
Prevention of Cardiovascular Diseases Caused by Complex Treatment of Patients With Primary Operated Breast Cancer
To develop a method of medical prevention of cardiovascular diseases caused by cardiotoxicity against the background of complex treatment of patients with primary resectable breast cancer to reduce the risk of cardiovascular…
- Trial name
- NCT04588935
- Testing
- Bisoprolol; Perindopril;
- Where
- Belarus
- Volunteers
- 100 people
- Sponsor
- State Institution "Republican Scientific and Practical Center" Cardiology, Belarus
Primary Health Care, Quality of Health Care
Aligning Patients and Their Primary Care Providers
This project focuses on improving the patient-provider primary care visit interaction by addressing the need to align patient and provider priorities in a way that incorporates patients' goals and preferences while supporting the…
- Conditions
- Primary Health Care, Quality of Health Care, Comorbidity, Communication
- Trial name
- APP (NCT02707146)
- Testing
- Visit Planner, Attention Control Pamphlet, iPad
- Where
- United States
- Volunteers
- 750 people
- Sponsor
- Kaiser Permanente