Clinical trials: Comparative Study
Breast Neoplasms
Breast Lump Clipping Methods Comparison
Breast cancer is the most frequently diagnosed malignancy among women worldwide, with increasing rates in later life. It represents a significant healthcare challenge in low- and middle-income countries where limited access to…
- Trial name
- BLC (NCT07716644)
- Testing
- Breast Lesion Clip Placement
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- University of Faisalabad
Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction
Bipolar Resection vs Enucleation of Prostate
The aim of this study is to evaluate efficacy and safety of transurethral resection of the prostate and bipolar enucleation of the prostate.
- Conditions
- Benign Prostatic Hyperplasia (BPH) Requiring Surgical Resection, Benign Prostatic Hyperplasia With Outflow Obstruction, Benign Prostatic Hyperplasia With Symptomatic Lower Urinary Tract Symptoms, Benign Prostatic Hyperplasia With Lower Urinary Tract Symptoms
- Trial name
- TURP vs BiTUEP (NCT06983444)
- Testing
- TURP, TUEP
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- South Valley University
Ivermectin, Hydroxychloroquine
A Comparative Study on Ivermectin and Hydroxychloroquine on the COVID19 Patients in Bangladesh
COVID19 is a worldwide pandemic. Hence SARS-CoV-2 is a novel virus; there is no specific medication against it. Like other countries of the world, Bangladesh is also struggling in the case of treatment of this disease.
- Conditions
- Ivermectin, Hydroxychloroquine, COVID19
- Trial name
- NCT04434144
- Testing
- Ivermectin + Doxycycline, Hydroxychloroquine + Azithromycin
- Where
- Bangladesh
- Volunteers
- 116 people
- Sponsor
- Upazila Health & Family Planning Officer's (UHFPO) Office, Chakoria, Cox's Bazar
Video Laryngoscope, Airway
Comparative Study Between Combined Video Laryngoscope and Video Stylet Intubation Versus Combined Video Laryngoscope and Fiberoptic Intubation in a Simulated Difficult Airway
This study titled "Comparative Study Between Combined Video Laryngoscope and Video Stylet Intubation Versus Combined Video Laryngoscope and Fibreoptic Intubation in a Simulated Difficult Airway" aims to evaluate and compare two…
- Conditions
- Video Laryngoscope, Airway, Difficult Airway, Fiberoptic Guided Intubation
- Trial name
- NCT07470736
- Testing
- Video laryngoscope alone as a control, Video Laryngoscope plus Video Stylet, Video Laryngoscope plus Fiberoptic bronchoscope
- Where
- Malaysia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- National University of Malaysia
Postoperative Pulmonary Dysfunction
Different Modes of Ventilation During Cardiopulmonary Bypass
66 patients divided into 3 groups with different modes of ventilation.
- Trial name
- NCT03824301
- Testing
- Volume controlled ventilation, Pressure controlled ventilation
- Where
- Egypt
- Volunteers
- 66 people
- Sponsor
- Ain Shams University
Episiotomy Wound
Steristrips Adhesive Tape Versus Subcuticular Suture for Episiotomy Repair in Primigravid Obese Women
This study will be done to question the superiority of using skin adhesive tape (® Steri-Strip) closure in wound pain and healing over the traditional running absorbable subcuticular suture technique in perineal repair after…
- Trial name
- NCT03702751
- Testing
- Adhesive tape, Continuous subcuticular skin suturing
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Fibromyalgia
Newer Antidepressants in Combination With Pregabalin for Fibromyalgia Syndrome
Background: The investigator hypothesized that the combined use of pregabalin and paroxetine would be associated with comparable Somatic Symptoms Scale-8 (SSS-8) and higher tolerability than amitriptyline or venlafaxine.
- Trial name
- NCT02451475
- Testing
- Amitriptyline, Venlafaxine, Paroxetine
- Volunteers
- 75 people
- Sponsor
- Mansoura University
Continuous Adductor Canal Block, Infiltration Between The Popliteal Artery and Capsule of The Knee
Effect of Continuous Adductor Canal Block Versus Continuous Adductor Canal Block With Additional Infiltration Between The Popliteal Artery and Capsule of The Knee (IPACK) After Arthroscopic Knee Surgeries
This study aims to evaluate the effect of Continuous Adductor Canal Block only versus adding posterior knee block, known as the Infiltration between the Popliteal Artery and Capsule of the Knee (IPACK) block with Continuous…
- Conditions
- Continuous Adductor Canal Block, Infiltration Between The Popliteal Artery and Capsule of The Knee, Arthroscopic Knee Surgeries
- Trial name
- NCT06802419
- Testing
- Continuous adductor canal block, Continuous Adductor Canal Block with additional Infiltration between The Popliteal Artery and Capsule
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Ain Shams University
Type 2 Diabetes Mellitus
A Study to Assess the Safety and Efficacy of ASP1941 in Combination With Dipeptidyl Peptidase-4 (DPP-4) Inhibitor in Type 2 Diabetic Patients
This study is to evaluate long-term safety and efficacy after concomitant administration of ASP1941 and DPP-4 inhibitor in Japanese patients with type 2 diabetes mellitus.
- Trial name
- NCT01242228
- Testing
- ipragliflozin, DPP-4 inhibitor
- Where
- 6 sites in Japan
- Volunteers
- 106 people
- Sponsor
- Astellas Pharma Inc
Hip Injuries, Acetabular Labral Tear
A 12 Months Prospective Study Comparing Functional Outcome Scores in Hip Arthroscopic Labral Repair Versus Debridement
This study aims to address hip labral tears and compare arthroscopic labral repair versus debridement in non-athletic population aged 20 to 50 years old, including both sexes.
- Conditions
- Hip Injuries, Acetabular Labral Tear, Femoro Acetabular Impingement
- Trial name
- NCT06288867
- Testing
- Arthroscopic Labral Repair, Arthroscopic Labral Debridement
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Bronchial Asthma
Efficacy and Safety of Roflumilast in Japanese Patients With Bronchial Asthma (20 to 70 y) (APTA-2217-05).
The aim of the study is to investigate the effect of roflumilast (APTA-2217) on lung function in patients with asthma. Roflumilast will be administered orally once daily.
- Trial name
- NCT00242307
- Testing
- Roflumilast
- Where
- Japan
- Volunteers
- 450 people
- Sponsor
- AstraZeneca
Blood Loss, Postoperative, Blood Loss, Surgical
EFFECT OF TRANEXAMIC ACID ON PERIOPERATIVE BLOOD LOSS IN REAMED INTRAMEDULLARY NAILING OF DIAPHYSEAL FEMORAL AND TIBIAL FRACTURES: A PROSPECTIVE COMPARATIVE STUDY
Perioperative blood loss is one of the most frequently encountered and significant complications of spine surgery. Intraoperative and post-operative bleeding cause various complications and negatively affect patient outcomes.
- Conditions
- Blood Loss, Postoperative, Blood Loss, Surgical, Femoral Fracture, Tibial Fracture
- Trial name
- NCT07625709
- Testing
- Intervention with Tranexamic Acid, Control group (Normal Saline)
- Where
- Nepal
- Volunteers
- 54 people
- Sponsor
- Kathmandu University School of Medical Sciences
Dermatitis, Atopic, Eczema
Comparative Study of Crisaborole vs. Tacrolimus in Atopic Dermatitis
This study will compare the efficacy and safety of crisaborole ointment with tacrolimus ointment, in the treatment of patients with mild-to-moderate atopic dermatitis.
- Trial name
- NCT07367932
- Testing
- Application of crisaborole twice daily, Tacrolimus ointment in atopic dermatitis
- Volunteers
- 30 people
- Sponsor
- Cairo University
Diabetes Mellitus, Type 2
A Study Using Medical Records of Danish People With Type 2 Diabetes Comparing Empagliflozin and Glucagon-Like Peptide-1 Receptor Agonists (GLP1-RA) in the Occurrence of Serious Cardiovascular Outcomes
The primary research question is to evaluate whether, among patients with type 2 diabetes mellitus (T2D), initiation of empagliflozin changes the adjusted incidence of outcomes compared with initiation of Glucagon-Like Peptide-1…
- Trial name
- NCT03993132
- Testing
- Empagliflozin, Liraglutide
- Where
- Denmark
- Volunteers
- 26,774 people
- Sponsor
- Boehringer Ingelheim
Liver Resection
A Trial to Compare Pringle Maneuver With Either Infrahepatic Inferior Vena Cava Clamping or Low Central Venous Pressure
The purpose of this study is to better comprehend the benefits and efficacy of portal triad clamping with infrahepatic IVC clamping during complex hepatectomy.
- Trial name
- NCT01355887
- Where
- China
- Volunteers
- 192 people
- Sponsor
- Huazhong University of Science and Technology
Fecal Incontinence, Bowel Incontinence
Fecal Incontinence Treatment (FIT) Study
Patients with severe fecal incontinence (FI), defined as two or more episodes of staining, solid or liquid FI per week, and who meet the inclusion criteria for Injection of Solesta (INJ; an inert bulking agent), or Biofeedback…
- Trial name
- NCT03811821
- Testing
- Biofeedback, Injection
- Where
- 6 sites in United States
- Volunteers
- 275 people
- Sponsor
- Mayo Clinic
Physiological Root Resorption of Primary Teeth
The Effect of Physiological Root Resorption in Primary Teeth on the Success of Pulpotomy Treatment
The aim of our study was to evaluate the effect of physiological root resorption on the success of pulpotomy treatment performed using a calcium silicate-based material on primary second molars with deep dentin caries.
- Trial name
- NCT07834814
- Testing
- Pulpotomy treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Aydin Adnan Menderes University
Thoracic Sympathectomy
Analgesic Effect of Erector Spinae Versus Serratus Anterior Plane Block for Thoracoscopic Sympathectomy
Thoracic incisions are painful and associated with chronic post-surgical pain and inadequate analgesia is associated with poorer postoperative outcomes.
- Trial name
- NCT04486014
- Testing
- Erector spinae plane block, Serratus anterior plane block
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Nausea With Vomiting Chemotherapy-Induced
BMT-08: A Comparative Effectiveness Study of Transdermal Granisetron to Ondansetron
Patients undergoing either an autologous or allogeneic hematopoietic stem cell transplant (HSCT) and receiving preparative chemotherapy experience a considerable amount of chemotherapy-induced nausea and vomiting (CINV).
- Trial name
- NCT04150614
- Testing
- Granisetron Transdermal Patch, Intravenous Dexamethasone, Ondansetron
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Illinois at Chicago
Sleep Apnea, Obstructive
Comparison of the Pentax AWS® With the Macintosh Laryngoscopic Intubation in Obstructive Sleep Apnea Syndrome Patients
The Pentax-AWS_ system (AWS; Pentax Corporation, Tokyo, Japan) is a new rigid indirect laryngoscope which has an integrated tube passage function.
- Trial name
- NCT01428570
- Testing
- Pentax-AWS (AWS; Pentax Corporation, Tokyo, Japan)
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Kyunghee University Medical Center
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