Clinical trials: Comorbid Personality Disorders
Comorbidity, Substance Abuse
ENGAGE - Meeting Mental Health Needs of Complex Comorbid Patients
Scotland has higher rates of suicide than other parts of the UK, an average rate of 15.1 per 100,000 in Scotland compared to 11.4 for England and Wales. The Scottish Government is committed to reducing suicide by 2013.
- Conditions
- Comorbidity, Substance Abuse, Personality Disorder
- Trial name
- ENGAGE (NCT00980824)
- Testing
- Cognitive behavioural therapy, Standard treatment
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Glasgow
Alcohol Use Disorder, Borderline Personality Disorder
Nalmefene in Alcohol Dependence and Borderline Personality Disorder
The objective is to study the effectiveness of Nalmefene in decreasing alcohol intake in subjects with alcohol use disorder and comorbid BPD.
- Trial name
- NCT02752503
- Testing
- Nalmefene
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Bipolar I Disorder, Borderline Personality Disorder
Effects of Comorbid Personality Disorder on the Treatment of Bipolar I Disorder
This study will examine the impact of comorbid personality disorder on the outcome of treatment among patients with bipolar I disorder.
- Trial name
- NCT00178061
- Testing
- Interpersonal Social Rhythm Therapy (IPSRT)
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Pittsburgh
Posttraumatic Stress Disorder, Borderline Personality Disorder
Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder and Borderline Personality Disorder (PTSD-BPD)
Posttraumatic Stress Disorder (PTSD) with co-occurring Borderline Personality Disorder (BPD) (i.e., PTSD-BPD) is common (as high as 58%), debilitating, costly, and limited treatment options available for this population.
- Trial name
- NCT04230668
- Testing
- Cognitive Processing Therapy with Suicide Risk Management, Treatment as Usual with Suicide Rick Management
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Palo Alto University
Posttraumatic Stress Disorder (PTSD), Avoidant Personality Disorder
Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and CPD
The goal of PROSPER-C is to study effectiveness of ImRs compared to integrated SFT-ImRs in treatment-seeking, adult patients with comorbid PTSD and Cluster C Personality Disorder (CPD).
- Conditions
- Posttraumatic Stress Disorder (PTSD), Avoidant Personality Disorder, Dependent Personality Disorder, Obsessive Compulsive Personality Disorder
- Trial name
- PROSPER-C (NCT03833531)
- Testing
- ImRS, SFT
- Where
- Netherlands
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Arkin
Depression, Comorbid Personality Disorders
Effects of Vagus Nerve Stimulation (VNS) as a Treatment of Persistent Depression With Comorbid Personality Disorders (Impulse-VNS
In this monocentre two-armed double blind randomised placebo-controlled study - in which the control group obtains the VNS therapy within a defined space of time after 12 weeks - the impact of vagus nerve stimulation on…
- Trial name
- Impuls-V (NCT01119053)
- Testing
- VNS Pulse Model 102
- Where
- Germany
- Sponsor
- University Medical Center Goettingen
Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
Extended Group Written Exposure Therapy for Comorbid PTSD and BPD (Traits)
The goal of this open label trial is to evaluate the effectiveness of virtual group extended Written Exposure Therapy (GE-WET) in reducing Post-Traumatic Stress Disorder (PTSD) symptoms in patients with comorbid PTSD and…
- Trial name
- NCT07576387
- Testing
- Group Written Exposure Therapy
- Where
- Canada
- Volunteers
- 63 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Posttraumatic Stress Disorder (PTSD), Borderline Personality Disorder (BPD)
Effectiveness of PTSD-treatment Compared to Integrated PTSD-PD-treatment in Adult Patients With Comorbid PTSD and BPD
The goal of PROSPER-B is to study effectiveness of EMDR compared to integrated DBT-EMDR in treatment-seeking, adult patients with comorbid PTSD and Borderline Personality Disorder (BPD).
- Trial name
- PROSPER-B (NCT03833453)
- Testing
- EMDR, DBT
- Where
- Netherlands
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Arkin
Anxiety Disorders, Depressive Disorders
Short-term, Intensive Psychodynamic Group Therapy Versus Cognitive-behavioral Group Therapy in the Day Treatment
Background: Psychodynamic and cognitive-behavioral group therapies are frequently applied in day hospitals in the treatment of anxiety disorders, and comorbid depressive or personality disorders in Poland.
- Conditions
- Anxiety Disorders, Depressive Disorders, Personality Disorders
- Trial name
- NCT02126787
- Testing
- Intensive Group Analytic Psychotherapy, Intensive transdiagnostic cognitive-behavioral group therapy
- Where
- Poland
- Volunteers
- 123 people
- Sponsor
- Medical University of Warsaw
Borderline Personality Disorder, Stress Disorders, Post-Traumatic
Narrative Exposure Therapy in Women With Borderline Personality Disorder and Posttraumatic Stress Disorder
Narrative Exposure Therapy (NET) is an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity.
- Trial name
- NCT02517723
- Testing
- Narrative Exposure Therapy, Dialectical Behavior Therapy, Standard Inpatient Care
- Where
- Germany
- Volunteers
- 67 people
- Sponsor
- Evangelisches Krankenhaus Bielefeld gGmbH