Clinical trials: Community Acquired Pneumonia
Community Acquired Pneumonia, Pneumonia
Standardized Emergency Care for Community Acquired Pneumonia (CAP)
Community acquired pneumonia (CAP) is associated with a high in-hospital mortality. Standardization of diagnostics and adherence to sepsis bundles in the emergency department (ED) are associated with reduced mortality in patients…
- Conditions
- Community Acquired Pneumonia, Pneumonia, Infection
- Trial name
- NCT01963000
- Where
- Germany
- Volunteers
- 2,819 people
- Sponsor
- Klinikum Nürnberg
Community-acquired Pneumonia
Clarithromycin Treatment to Prevent Sepsis Progression in CAP (REACT)
The primary objective of the REACT randomized clinical trial (RCT) is to optimize the clinical benefit from adjunctive clarithromycin treatment shown in the ACCESS trial and to provide evidence for the clinical benefit of early…
- Trial name
- REACT (NCT06294600)
- Testing
- Clarithromycin 500mg, Tablets
- Where
- 24 sites in Greece
- Volunteers
- 330 people
- Sponsor
- Hellenic Institute for the Study of Sepsis
Community Acquired Pneumonia (CAP)
ItAlian ReGistry Of pNeumoniA in immUnocompromised paTients (ARGONAUT)
This multicentric, prospective study aims at: evaluating the prevalence, etiology, characteristics, and 1one-year outcomes of immunocompromised patients hospitalized for Community-Acquired Pneumonia (CAP); conducting biochemical…
- Trial name
- ARGONAUT (NCT06755814)
- Where
- Italy
- Volunteers
- 1,298 people
- Sponsor
- Societa Italiana di Pneumologia
Community Acquired Pneumonia
A Retrospective Study on Hospitalized Patients With Community-acquired Pneumonia in China (CAP-China)
The purpose of this study is to evaluate the disease burden of hospitalized patients with CAP and healthcare-associated pneumonia (HCAP) in real life of China .
- Trial name
- RSCAP-China (NCT02489578)
- Testing
- other
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- Capital Medical University
Pneumonia, Sepsis
A Safety and Efficacy Study of Hospitalized Patients With Community-Acquired Pneumonia and Sepsis
The objective of this study is to demonstrate the safety and efficacy of IC14 in the treatment of hospitalized patients with community-acquired pneumonia and sepsis.
- Trial name
- NCT00042588
- Testing
- Recombinant Chimeric Monoclonal Antibody
- Where
- United States
- Sponsor
- ICOS Corporation
Pneumonia, Bacterial
Prevalence and Serotype of Streptococcus Pneumoniae Hospitalized Adult With Community-Acquired Pneumonia
Streptococcus Pneumoniae is one of the etiology in severe CAP and accounts for about 60-75% of cases and is likely to be the leading cause of unknown etiologic pneumonia.
- Trial name
- HACAP (NCT05173727)
- Where
- Indonesia
- Volunteers
- 355 people
- Sponsor
- Dr Cipto Mangunkusumo General Hospital
Community-acquired Pneumonia, Skin Infection
Improving Short Course Treatment for Common Pediatric Infections
Randomized quality improvement trial to improve the proportion of cases of community-acquired pneumonia (CAP) treated with no more than 5 days of antibiotics the proportion of cases of skin and soft tissue infections (SSTI)…
- Trial name
- NCT06087809
- Testing
- Education and feedback, Clinical decision support
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Boston Children's Hospital
Pneumonia, Pneumococcal, Pneumococcal Infections
Study Evaluating the Effiacy of a 13-Valent Pneumococcal Conjugate Vaccine (13vPnC) in Adults
The purpose of this study is to assess the efficacy of 13-valent pneumococcal conjugate vaccine in the prevention of the first episode of vaccine-type pneumococcal community-acquired pneumonia in adults.
- Conditions
- Pneumonia, Pneumococcal, Pneumococcal Infections, 13-valent Pneumococcal Vaccine
- Trial name
- CAPITA (NCT00744263)
- Testing
- VACCINE: 13-valent pneumococcal conjugate vaccine
- Where
- 159 sites in Netherlands
- Volunteers
- 84,496 people, healthy volunteers welcome
- Sponsor
- Pfizer
Sepsis, Acute Respiratory Distress Syndrome
A Validation Study on a Prognostic Prediction Model for Respiratory Tract Infections
This study adopted a prospective, single-center, open-label design, aiming to evaluate the efficacy of the RTI clinical outcome prediction model in predicting clinical outcomes in subjects with acute respiratory tract infections.
- Conditions
- Sepsis, Acute Respiratory Distress Syndrome, Community Acquired Pneumonia, Transcriptome
- Trial name
- NCT07109310
- Testing
- RTImodel001
- Volunteers
- 150 people
- Sponsor
- Peking Union Medical College Hospital
Community-acquired Pneumonia
Clinical Pathway Based on Procalcitonin Levels for the Management of Community-acquired Pneumonia in Outpatients
A clinical protocol was developed for the management of adult outpatients with community-acquired pneumonia (CAP) and Pneumonia Severity Index risk classes I-II.
- Trial name
- NCT02600806
- Testing
- Azithromycin, Levofloxacin
- Where
- Spain
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Pneumonia, Community-Acquired, Bacterial Pneumonia
Efficacy and Safety of Faropenem in Bangladeshi Adult Patients With Community-Acquired Bacterial Pneumonia (CABP)
The goal of this clinical trial is to evaluate the efficacy and safety of faropenem in comparison to co-amoxiclav and clarithromycin in Bangladeshi adults diagnosed with community-acquired bacterial pneumonia (CABP).
- Trial name
- NCT06804096
- Testing
- Faropenem, Co-amoxiclav, Clarithromycin 500 mg
- Where
- 2 sites in Bangladesh
- Volunteers
- 129 people
- Sponsor
- Dr. Md. Alimur Reza
Community Acquired Pneumonia, Respiration Failure
A Molecular Toolkit for the Microbial Investigation of Severe Community Acquired Pneumonia
Severe community acquired pneumonia is common and associated with high mortality. Conventional microbiological diagnostics identify pathogens in approximately half of cases, which is inadequate for both clinical and…
- Conditions
- Community Acquired Pneumonia, Respiration Failure, Pneumonia
- Trial name
- S-CAP (NCT02963142)
- Where
- United Kingdom
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Community-Acquired Pneumonia, Fraility
Frailty and Outcomes in Older Emergency Department Patients With Pneumonia
Pneumonia is one of the leading causes of infection-related mortality in the older population. Traditional severity scores used in emergency departments, such as the Pneumonia Severity Index (PSI) and CURB-65, primarily focus on…
- Conditions
- Community-Acquired Pneumonia, Fraility, Hospitalizations
- Trial name
- NCT07442656
- Testing
- Clinical frailty scale, Clinical Frailty Scale (CFS)
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people
- Sponsor
- Ege University
Community-acquired Pneumonia
Corticosteroid Treatment for Community-Acquired Pneumonia - The STEP Trial
Background: An intact hypothalami-pituitary-adrenal (HPA) axis with an effective intracellular anti-inflammatory activity of glucocorticoids is indispensable for host survival during stress upon exposure to an infectious agent.
- Trial name
- STEP (NCT00973154)
- Testing
- Prednisone
- Where
- 7 sites in Switzerland
- Volunteers
- 800 people
- Sponsor
- University Hospital, Basel, Switzerland
Infectious Disease of Lung, Molecular Diagnosis
Clinical Impact of a Multiplex Rapid Diagnostic Pneumonia Panel Testing in Critically-ill Patients With Severe Hospital-acquired Pneumonia, Ventilator-associated Pneumonia and Community-acquired Pneumonia With High Risk of Multidrug Resistant Pathogen
The objective of the research is to ascertain the influence of a syndromic mutiplex PCR assay (FilmArray) on the management of patients hospitalised in the ICU for severe respiratory disease.
- Conditions
- Infectious Disease of Lung, Molecular Diagnosis, Pneumonia
- Trial name
- NCT06782607
- Testing
- Pneumonia Panel by FilmArray
- Where
- Thailand
- Volunteers
- 80 people
- Sponsor
- Mahidol University
Acute Respiratory Infections, Febrile Illnesses
The Fever Clinic Acute Respiratory Cohort
This prospective cohort study aims to characterize the natural progression and outcomes of acute respiratory infections among patients presenting to fever clinics.
- Conditions
- Acute Respiratory Infections, Febrile Illnesses, Community-acquired Pneumonia, Viral Respiratory Tract Infections
- Trial name
- FACTS (NCT07278700)
- Testing
- No intervention involved
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Fudan University
Community-acquired Pneumonia
Physical Training During Hospital Admission With Community-Acquired Pneumonia
The purpose of this study is to assess the effect of standard usual care combined with daily supervised physical training during hospitalization with community-acquired pneumonia (CAP) compared to standard usual care alnone.
- Trial name
- NCT04094636
- Testing
- In-bed cycling, Exercise booklet
- Where
- Denmark
- Volunteers
- 210 people
- Sponsor
- Nordsjaellands Hospital
Infections, Community Acquired Pneumonia
Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)
This is a study of safety and effectiveness of ceftaroline fosamil in children with Community Acquired Bacterial Pneumonia receiving antibiotic therapy in the hospital.
- Trial name
- NCT01530763
- Testing
- Ceftaroline fosamil, Ceftriaxone, amoxicillin clavulanate
- Where
- 44 sites in United States, Argentina and 7 more
- Volunteers
- 161 people
- Sponsor
- Forest Laboratories
Community Acquired Pneumonia
Comparative Study of NXL103 Versus Comparator in Adults With Community Acquired Pneumonia
The purpose of this study is to compare the efficacy, safety and tolerance of 2 different dose levels of oral NXL103 with oral comparator in the treatment of community acquired pneumonia in adults
- Trial name
- NCT00653172
- Testing
- NXL103, comparator
- Where
- 60 sites in Chile, Croatia and 7 more
- Volunteers
- 302 people
- Sponsor
- Novexel Inc
Community-Acquired Infections
Cohort Study on the Treatment of Severe Pneumonia with Traditional Chinese Medicine
This is a multicenter, prospective cohort study, with syndrome differentiation and treatment of traditional Chinese medicine as the exposure factor.
- Trial name
- NCT06613659
- Testing
- traditional Chinese medicine (TCM), non traditional Chinese medicine (non-TCM)
- Where
- China
- Volunteers
- 1,016 people
- Sponsor
- Henan University of Traditional Chinese Medicine