Clinical trials: Colonoscopy Technique
Predictive Cancer Model
Innovative Approach to Detect Recurrent Colorectal Lesions With Surveillance Via Mutation Analysis & Clinical Phenotype
It is known that the development of colorectal adenoma is dependent on the appearance of somatic mutations in protooncogenes and tumor suppressor genes.
- Trial name
- MTG (NCT05929365)
- Testing
- colonoscopy
- Where
- Czechia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Military University Hospital, Prague
Colonoscopy
Can Simple and Inexpensive Techniques Enhance Patient Comfort
This research study compares two methods of performing colonoscopy without sedation. The standard method is to insert the colonoscope without adding any water to the colon, and when colonic spasms occur during the examination…
- Trial name
- NCT00747084
- Testing
- Colonoscopy
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colorectal Neoplasms
Comparative Efficacy of Water & Indigo Carmine vs. Water or Air Method on Adenoma Detection Rate (ADR) - a Randomized Controlled Trial (RCT)
Adenoma detection rate (ADR) is a quality indicator of colonoscopy performed for colorectal cancer screening. Population studies have shown that traditional air colonoscopy fails to eliminate post screening colonoscopy cancers or…
- Trial name
- NCT01607255
- Testing
- Indigo carmine, water (exchange) method, water (exchange) plus dye method
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Colorectal Cancer Screening
Comparison of on Demand Sedation With Study Method Versus on Demand Sedation With Conventional Method for Performing Colonoscopy for Colorectal Cancer Screening and Surveillance
Hypothesis 1. Study method achieves lower requirement for medications 2. Study method increases overall cecal intubation with comparable assessment of current experience and patient willingness to repeat future colonoscopy…
- Trial name
- NCT00920751
- Testing
- Water infusion, Air insufflation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- East Bay Institute for Research and Education
Polyps
Experience and Enhancement: Improving Colonoscopic Polyp Detection
The study looks at 2 hypotheses in 2 patient groups: 1. Are more experienced endoscopists better at detecting subtle lesions (polyps) on the lining of the colon (large bowel) than less experienced endoscopists? 2.
- Trial name
- NCT00237276
- Testing
- colonoscopy
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- London North West Healthcare NHS Trust
Colorectal Polyp
The Impact of Repeated Colonoscopic Insert Method on the Detection Rate of Adenomas in the Sigmoid Colon
Colorectal cancer (CRC) is a malignant tumour originating from the colorectal mucosal epithelium, with rising incidence and mortality rates.
- Trial name
- NCT06186778
- Testing
- secondary colonoscopy, conventional colonoscopy
- Where
- China
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Jianning Yao
Colonoscopy
Sedation Techniques for Outpatient Colonoscopy
This was a prospective, randomized, single-blind controlled clinical trial comparing three sedative regimens for outpatient colonoscopy.
- Trial name
- NCT04686058
- Testing
- Propofol 10 MG/ML Injection, Midazolam injection, Pethidine Hydrochloride 50 Mg/mL Solution for Injection
- Where
- Malaysia
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Colon Cancer Screening
Randomized Control Trial Comparing the Incidence of Loop Formation in Colonoscopy Techniques
A colonoscopy is a common procedure used to check for problems in the colon, such as disease or other health issues. Although it's widely used, one challenge is that the flexible tube used in the procedure (called a colonoscope)…
- Trial name
- NCT07245173
- Testing
- colonoscopy
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- Memorial University of Newfoundland
Gastrointestinal Diseases, Digestive System Diseases
Warm Water and Unsedated Colonoscopy
Unsedated or slightly sedated colonoscopy has fast recovery time, less cost and lower or no incidence of drug-related side effects. May be slightly painful or discomforting for the patient.
- Trial name
- WW (NCT01463319)
- Testing
- air insufflation, warm water irrigation
- Where
- 2 sites in Italy
- Volunteers
- 818 people, healthy volunteers welcome
- Sponsor
- Presidio Ospedaliero Santa Barbara
Adenomatous Polyp, New Imaging Techniques in Colonoscopy
Narrow Band Imaging Colon Polyp Study
In this study the investigators hypothesize that High Definition White Light colonoscopy and narrow band imaging (NBI) will detect a higher number of adenomas compared to standard definition white light colonoscopy.
- Trial name
- NCT00614770
- Testing
- standard of care colonoscopy, colonoscopy
- Where
- 2 sites in United States
- Volunteers
- 630 people, healthy volunteers welcome
- Sponsor
- Kansas City Veteran Affairs Medical Center
Colonoscopy
Comparing Warm Versus Cool Temperature Water During Colonoscopy
The purpose of this study will be to determine if the temperature of water used during insertion of colonoscopy makes a difference in patient discomfort and sedation requirements.
- Trial name
- NCT01322724
- Testing
- Warm vs Cool water
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Colorectal Adenoma, Colorectal Polyp
Examining Techniques on Adenoma Miss Rate in Proximal Colon
The primary aim of this study is to explore the usefulness of re-examination and retroflexion on adenoma miss rate (AMR) in the proximal colon.
- Trial name
- SINOCOLO2017 (NCT03355443)
- Testing
- Retroflexion, Re-examination
- Where
- 3 sites in China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Colorectal Neoplasms
Risk-adapted Screening in First-degree Relatives of Patients With Colorectal Cancer
BACKGROUND: First-degree relatives of patients with colorectal cancer are at increased risk for colorectal cancer as well. Nevertheless, participation in the German national screening program stagnates at 2-3 percent per year…
- Trial name
- FAMKOL (NCT01903395)
- Testing
- Nurse-led counselling
- Where
- 33 sites in Germany
- Volunteers
- 313 people, healthy volunteers welcome
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Diabetes Mellitus, Obesity
Jejunal Luminal and Colonic Mucosa-Associated Microbiota in Metabolic Diseases: Methods, Identification and Causalities
This clinical study will investigate Jejunal Microbiota in Metabolic Diseases (Je-MiMe, n=45) and Colonic mucosa-associated Microbiota in Metabolic Diseases (Col-MiMe, n=45).
- Conditions
- Diabetes Mellitus, Obesity, Metabolic Disease
- Trial name
- JE/COL-MIME (NCT05186389)
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Colorectal Cancer
A New Method for Colorectal Cancer Screening: Colon Capsule Endoscopy Compared to Conventional Endoscopy
Introduction: Prevention of colorectal cancer (CRC) is feasible through polypectomy on screening colonoscopy. Patient acceptance remains the main limiting factor for execution.
- Trial name
- NCT00991003
- Testing
- Colon capsule endoscopy, Conventional Colonoscopy
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Colon Disease;, Rectal Disease
Ultrafine Endoscope for Colonoscopy in Diagnosis of Colorectal Diseases
This study is the evaluation of ultrafine endoscope (with small caliber and turning radius )for colonoscopy in decreasing abdominal pain of patients . 60 patients will be accepted in this trial.
- Trial name
- NCT02160210
- Testing
- Ultrafine Endoscope
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Youlin Yang ,MD
Colonoscopy
The Comparative Study Between Bowel Preparation Method
The purpose of this study is to compare the efficacy, acceptability and preparation-induced mucosal inflammation of PEG + ascorbic acid vs. PEG for colonoscopy.
- Trial name
- CSBPM (NCT01964417)
- Testing
- Colonoscopy after bowel cleansing
- Where
- South Korea
- Volunteers
- 319 people, healthy volunteers welcome
- Sponsor
- Inje University
Colonoscopy, Colon Disease
Three Distraction Methods for Pain Reduction During Colonoscopy
Colonoscopy is a common procedure to evaluate the gastrointestinal tract. The colonoscopy procedure can sometimes be uncomfortable and painful for the patient.
- Trial name
- NCT05378165
- Testing
- Music group, Stress ball group, Video group
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Colonic Transendoscopic Enteral Tubing
Methods of Colonic Transendoscopic Enteral Tubing
Colonic transendoscopic enteral tubing (TET) is a novel, safe, convenient, and reliable way for fecal microbiota transplantation (FMT) and the whole-colon enema treatment.
- Trial name
- NCT03621033
- Testing
- colonic transendoscopic enteral tubing
- Where
- 2 sites in China
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Nanjing Medical University
Colorectal Cancer, Colorectal Adenoma
Fecal DNA Methylation Test for Colorectal Cancer Screening
This is an observational, prospective study using fecal DNA methylation test to define the risk of suffering from advanced adenoma or colorectal cancer (CRC) compared to colonoscopy and fecal immunochemical test (FIT).
- Trial name
- NCT04823793
- Testing
- Stool DNA methylation detection
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)