Clinical trials: Collagen Disorder
Hypertension, Diabetes Mellitus
Effect of Recombinant Human Bone Morphogenetic Protein-2 With an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.
Effect of Recombinant Human Bone Morphogenetic Protein-2 with an Absorbable Collagen Sponge on Stability of Dental Implant: (Split Mouth Randomized Clinical Trial Study.
- Conditions
- Hypertension, Diabetes Mellitus, Blood Disease
- Trial name
- rhBMP-2 (NCT05719181)
- Testing
- rhBMP-2
- Where
- Iraq
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Ehlers-Danlos Syndromes (EDS)
CLINICAL AND BIOLOGICAL DATABASE OF PATIENTS WITH NON-VASCULAR EHLERS-DANLOS SYNDROMES
The Rare Disease Reference Center (CRMR) for Non-Vascular Ehlers-Danlos Syndromes (NV-EDS) at the Raymond Poincaré University Hospital provides diagnosis and care for patients with non-vascular Ehlers-Danlos syndrome.
- Trial name
- BASE SED-NV (NCT07899489)
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Peri-Implantitis
The Adjunctive Effect of Soft Tissue Augmentation Procedures of Moderate-severe Peri-implantitis
The key objective of the study is to compare the effects of soft tissue augmentation using a volume stable collagen matrix or autogenous connective tissue graft or no soft tissue augmentation in addition to bone…
- Trial name
- NCT05415111
- Testing
- Subepithelial connective tissue, Volume stable Collagen Matrix, No soft tissue augmentation
- Where
- 3 sites in Germany, Singapore and 1 more
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nadja Naenni
Keloid, Alopecia Areata
Pain Outcomes Following Intralesional Corticosteroid Injections
Corticosteroid therapy, including intralesional and topical applications, has many indications within the fields of Dermatology, Plastic Surgery, and Orthopedics.
- Conditions
- Keloid, Alopecia Areata, Acne, Hypertrophic Scar
- Trial name
- NCT03630198
- Testing
- Corticosteroid with lidocaine, Corticosteroid with normal saline
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Rheumatic Disease
Patient Experiences in Rheumatology
Information was entered by mistake by a Research Assistant. Study never went beyond the initial discussion phase.
- Trial name
- NCT00346710
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Hand Rheumatism, Systemic Lupus Erythematosus Arthritis
Application of MRI for Musculoskeletal Involvement in SLE
Articular involvement can reach up to 95% within the chronic multisystemic manifestations of SLE (1). Originally, a non-erosive pattern of articular inflammation was described, but the emergence of more sensitive imaging…
- Trial name
- RMNLES (NCT04035265)
- Testing
- Blood test
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hospital del Mar
Tooth Loss
Bone Remodeling After Immediate Implant Placement With and Without Bone Grafting
This study compares two ways of placing a dental implant on the day of tooth extraction. One method will place a additional bone graft (derived from bovine bone) and the other group will not have the graft placed.
- Trial name
- NCT02174198
- Testing
- BioOss Collagen at the time of implant placement
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy Volunteers, Vascular Ehlers Danlos Syndrome
Non-Invasive Quantitative Imaging of Human Local Arterial Wall Elasticity Using Supersonic Shear Imaging
Arterial stiffness is associated with increased risk of cardiovascular events and death. Most of existing technique need dedicated device for arterial stiffness evaluation and indirect calculation of intra arterial pressure.
- Trial name
- ULTRAFASTECHO (NCT01096264)
- Testing
- SSI and SphygmoCor® evaluations
- Where
- France
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- French Cardiology Society
Venous Stasis, Deep Venous Thrombosis
Effects of External Leg Compression Devices on Healing and Blood Clotting
This study aims to compare two different external calf compression devices applied in healthy individuals. These devices are commonly used in medical care in order to prevent the formation of blood clots, for example during…
- Conditions
- Venous Stasis, Deep Venous Thrombosis, Healing Wound
- Trial name
- NCT03050671
- Testing
- Intermittent Pneumatic Compression, Rapid, Intermittent Pneumatic Compression, Slow
- Where
- Sweden
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Gingival Recession, Generalized
Comparison Between Connective Graft and Xenogeneic Matrix, in Patients With Multiple Gingival Recessions
Subepithelial connective tissue graft (SCTG) is considered the gold standard for root coverage treatment. However, it is associated with postoperative morbidity, limited amount of donor tissue, and longer surgical time.
- Trial name
- NCT03207984
- Testing
- Root coverage surgery
- Where
- Brazil
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Cesarean Section; Dehiscence, Scar Keloid
Patch With Onion Extract and Allantoin for C-section Scar
The wound healing is a process occurring in response to dermal injury. The resulting scar may have various characteristics ranging from fine-line and asymptomatic to hypertrophic scars and keloids.
- Conditions
- Cesarean Section; Dehiscence, Scar Keloid, Wound Heal
- Trial name
- NCT04046783
- Testing
- patch
- Where
- Italy
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University of Salerno
Sarcopenia, Collagen Degeneration
Effects of Whey Protein Supplementation Collagen Associated to Resistance Training in Older Woman
The main purpose of the present study was to investigate the effects of whey protein with collagen hydrolyzed following resistance training on body composition, muscular strength, functional capacity, and plasma-metabolism…
- Trial name
- NCT04621383
- Testing
- Whey protein plus collagen, Whey protein plus maltodextrin
- Where
- Brazil
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Londrina
Smartphone Addiction, Game Addiction, Video
Exploring the Effects of Smartphone and Game Addiction on Activity, Sleep, Stress, and Pain in Youth
This study aims to examine the relationship between smartphone and digital game addiction and various health indicators, including physical activity level, sleep quality, stress, fatigue, and musculoskeletal pain among young…
- Conditions
- Smartphone Addiction, Game Addiction, Video, Musculoskeletal Pain Disorder, Sleep
- Trial name
- NCT06994104
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Spinal Cord Injury, Bladder Dysfunction
Quantitative and Qualitative Changes in Neural Efferent Receptors
OBJECTIVE: 1. To study tissues from spinal cord injured patients with noncompliant bladders as well as neurologically intact patients with normal bladder compliance, analyzing both quantitative and qualitative neural efferent…
- Trial name
- NCT00472784
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Extraction Socket Healing, Extraction, Tooth
The Effect of Collagen In Tooth Extraction Procedures
This study is aimed at assessing the effect of an animal-derived collagen matrix on bone and soft tissues in the human teeth. Single-rooted teeth that are beyond restoration and in need of extraction will be included in the…
- Trial name
- NCT07270510
- Testing
- Collagen Matrix soft tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Altinbas University
Recession, Gingival
Palatal Volumetric Change Analysis Following Connective Tissue Graft With and Without Donor Site Augmentation
The goal of this randomized clinical trial is to compare whether soft tissue augmentation placed in the donor site following a gum graft harvesting leads to volumetric changes compared to non-augmented sites in the palate.
- Trial name
- NCT05961566
- Testing
- Use of collagen matrix after subepithelial connective tissue graft harvest
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Hailey Bivens
Skin Laxity, Skin Aging
Cucurbita Pepo Flowers Extract to Promote Skin Health
The aim of this cosmetic clinical trial is to learn if an extract of Cucurbita pepo flower (CpLfe) works to enhance skin health and resilience in adult women with photo-damage.
- Conditions
- Skin Laxity, Skin Aging, Skin Wrinkling
- Trial name
- EACpLfe22S01 (NCT06674005)
- Testing
- Cucurbita pepo L. Flowers Extract
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ritamaria Di Lorenzo
Pancreatic Tumor
Effect of Thrombin-containing Collagen-based Hemostatic Matrix
Under the hypothesis that collagen-based hemostatic agents improve the suppression of leakage of hemostatic pancreatic fluid at the surgical site during surgery, thrombin-containing collagen-based hemostatic agents are applied in…
- Trial name
- TCM (NCT04357483)
- Testing
- flowable thrombin containing collagen hemostat matrix, thrombin coated L-dopa contained collagen patch
- Where
- South Korea
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Asan Medical Center
Keloid
Examining the Therapeutic Potential of Botulinum Toxin Type A in the Treatment of Keloids
Keloids are a common form of hypertrophic scars that by definition last beyond 6 months and grow beyond the site of initial injury.
- Trial name
- NCT05330078
- Testing
- Botulinum toxin type A, Vehicle
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Streptococcus Group A
Prevalence of RHD, Pyoderma and Scabies in Children in Fiji
The purpose of this study is to estimate the number of cases of rheumatic heart disease, pyoderma, and scabies in school age children in Fiji.
- Trial name
- NCT00284843
- Where
- Fiji
- Volunteers
- 5,200 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)