Clinical trials: Cognitive Testing
Cocaine Dependence
Neuropsychological Rehabilitation on Cocaine/Crack Dependents
Cocaine/Crack Dependence has been associated with neuropsychological impairments mainly in executive functions and decision-making, which are predominantly managed by the prefrontal cortex (PFC) in the brain.
- Trial name
- NCT01914835
- Testing
- Motivational Chess
- Where
- Brazil
- Volunteers
- 56 people
- Sponsor
- University of Sao Paulo General Hospital
Depression, Anxiety
Developing and Testing of Culturally Adapted Cognitive Behavior Therapy (CaCBT) for Pashto Speaking Pakistanis and Afghans
CBT for common mental disorders has a strong evidence base in both the USA and the UK. There are wider cultural and linguistic differences between Non Pashtun and Pashtun population of Pakistan and Afghanistan and there is…
- Trial name
- NCT02797691
- Testing
- CaCBT, Medication/ Psychotherapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Peshawar Medical College
Huntington's Disease
FuRST 2.0 Cognitive Pre-Testing
The FuRST 2.0 scale is being developed as a Patient Reported Outcome (PRO) with information coming directly from the Huntington's Disease Gene Expansion Carrier (HDGEC) and companion through self-report.
- Trial name
- NCT02881931
- Testing
- FuRST 2.0
- Where
- 4 sites in United States, Canada
- Volunteers
- 75 people
- Sponsor
- CHDI Foundation, Inc.
Hepatic Encephalopathy, Cirrhosis, Liver
Rifamycin in Minimal Hepatic Encephalopathy
This is a randomized double-blind placebo-controlled trial of MHE in patients with cirrhosis using rifamycin SV-MMX 600mg BID vs placebo for 30 days with PK, safety, microbiota, brain function and brain MRI endpoints.
- Trial name
- RIVET (NCT04082780)
- Testing
- Rifamycin SV MMX
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Hunter Holmes Mcguire Veteran Affairs Medical Center
Heart Failure, Cardiac Failure
Heart Failure Insomnia Treatment Study
The purpose of this study is to compare a short, behavioral treatment for insomnia with sleep monitoring to determine whether these approaches are effective in reducing insomnia and improving sleep quality among patients with…
- Conditions
- Heart Failure, Cardiac Failure, Congestive Heart Failure, Insomnia
- Trial name
- H-FITS (NCT03636880)
- Testing
- Brief treatment for Insomnia, Sleep Monitoring
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Ohio State University
Traumatic Brain Injury, Acquired Brain Injury
Comparative Utility of Clinical Balance Measures in Traumatic Brain Injury
The purpose of this research study is to investigate how useful three balance tests are in predicting fall risk in the individual with traumatic brain injury (TBI).
- Conditions
- Traumatic Brain Injury, Acquired Brain Injury, Accidental Falls
- Trial name
- NCT02696538
- Testing
- Functional Gait Assessment, mini-Balance Evaluation Systems Test, Berg Balance Scale
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Suicidal Ideation/Behavior
Culturally Centered CBT Protocol for Suicidal Behaviors Among Youth in Mexico City
This NIMH R34 award application proposes to conduct an adaptation, implementation, and pilot testing of the culturally centered CBT protocol, the Socio-Cognitive Behavioral Therapy for Suicidal Behaviors (SCBTSB), among suicidal…
- Trial name
- NCT06885047
- Testing
- Socio-Cognitive Behavioral Therapy for Suicidal Behavior (SCBT-SB), Treatment as usual
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Bradley Hospital
Mental Health and General Well-being
The Influence of Mindfulness on the Link Between Consumer Culture Values and Well-being
The study is a three-arm intervention, where students are randomly assigned to one of three conditions: Teacher-led group-based MBCT, Self-guided MBCT using an audio book, or 'wait list' control.
- Trial name
- NCT03079154
- Testing
- Teacher-led MBCT course, Self-guided MBCT course
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Sussex
Mild Cognitive Impairment
A Study of a Self-Administered Memory Screening Test With Automated Reporting (SAMSTAR) in Participants With Mild Cognitive Impairment
The purpose of this study is to evaluate the psychometric properties of a Self-administered Memory Screening Test with Automated Reporting (SAMSTAR) adapted from the Rey Auditory Verbal Learning Test (RAVLT) in normal control…
- Trial name
- NCT02419183
- Testing
- SAMSTAR, RAVLT
- Where
- 2 sites in United States
- Volunteers
- 153 people
- Sponsor
- Janssen Research & Development, LLC
Combat Disorders, Post-traumatic Stress Disorder
Treatment of Older Veterans With Chronic Posttraumatic Stress Disorder
This project represents the first randomized clinical trial of psychotherapy for older veterans with posttraumatic stress disorder (PTSD). It will compare relaxation training (RT) to prolonged exposure therapy (PE).
- Trial name
- NCT00539279
- Testing
- Prolonged Exposure Therapy (PE), Relaxation Training (RT)
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- US Department of Veterans Affairs
Schizophrenia, Memory Disorders
The Effects of Atomoxetine on Cognition and Brain Function Based on Catechol-O-methyltransferase(COMT) Genotype
This study will evaluate whether Atomoxetine improves cognition in healthy volunteers as well as patients with schizophrenia. Atomoxetine is a drug that has been Food and Drug Administration (FDA) approved for Attention Deficit…
- Conditions
- Schizophrenia, Memory Disorders, Cognition Disorders
- Trial name
- Atomoxetine (NCT00548327)
- Testing
- Atomoxetine, Functional magnetic resonance imaging, Neuropsychological Testing
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Postoperative Cognitive Abilities
Postoperative Sleep Disturbances Role in Cognitive Test Results After Fast-track Hip and Knee Arthroplasty
The purpose of this study is to evaluate sleep cycle before and after fast-track arthroplasty (3 days before and 10 days after) combined with cognitive testing preoperatively, on postoperative day 1,2,10.
- Trial name
- NCT01383369
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Alzheimer Disease, Mild Cognitive Impairment
Optina Diagnostics' Cerebral ß-Amyloid Status (CAS) Test
This observational, cross-sectional study is designed to validate a novel diagnostic test for the detection of phenotypic changes in the retina that correlate with likely PET amyloid status (negative or positive), to aid in the…
- Conditions
- Alzheimer Disease, Mild Cognitive Impairment, Mild Dementia
- Trial name
- REPHRASE (NCT05107882)
- Where
- 7 sites in United States, Canada
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Optina Diagnostics Inc.
Adverse Mental/Physical Effects of Low Dose S. Tortuosum.
Safety Study of the Effect of Scelectium Tortuosum (as Zembrin®)in Aged Normals
Phosphodiesterase is a candidate for the Rx \& prevention of cognitive and psychotic disorders. Since caffeine targets primarily PDE4(Phosphodiesterase subtype 4), caffeine analogs have been developed to mimic the actions of…
- Trial name
- NCT01805518
- Testing
- Scelectium Tortuosum
- Where
- Puerto Rico
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Woodbury, Michel, M.D.
Multiple Sclerosis
Testing the Feasibility of Computer-based Cognitive Training in Individuals with Multiple Sclerosis Living in the Community
Cognitive impairments are common in multiple sclerosis (MS) diagnosed both at the onset and throughout the disease course. Poor cognitive abilities have been associated with poor outcomes such as higher levels of unemployment…
- Trial name
- NCT06608797
- Testing
- Learning and memory training
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Kessler Foundation
Epilepsy, Functional Neurological Disorder
EXercise-induced PhysioLogical Adaptations In Neurological Disorders
The goal of this study is to investigate how a one-time exercise session influences different parameters of brain function in people with neurological diseases compared to healthy volunteers.
- Conditions
- Epilepsy, Functional Neurological Disorder, Mild Cognitive Impairment, Dementia
- Trial name
- EXPLAIN (NCT07883720)
- Testing
- Acute Exercise
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Physical Activity, Mental Health Wellness 1
Physical Exercise for Education ('Fit to Study')
Neuroscience evidence suggests that physical exercise can influence brain function and structure, both immediately and in the long-term.
- Conditions
- Physical Activity, Mental Health Wellness 1, Cognitive Function 1, Social, Academic Attainment
- Trial name
- FTS (NCT03286725)
- Testing
- Physical Education (PE) Programme
- Where
- United Kingdom
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Stroke
Predicting Cognitive Development in Younger Stroke Patients Using the Oxford Cognitive Screen
The purpose of this study is to investigate whether Oxford Cognitive Screen (OCS) can be used as a predictive tool during hospital admission in younger (<65 years) stroke patients, i.e.
- Trial name
- STROKY (NCT05612815)
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Bispebjerg Hospital
Mild Cognitive Impairment
The Role of Ophthalmologic Tests and EEG Imaging in Alzheimer's Disease
Alzheimer's disease (AD) is a prevalent, long-term progressive degenerative disorder with great social impact. It is currently thought that, in addition to neurodegeneration, vascular changes also play a role in the…
- Trial name
- NCT04277767
- Testing
- observational
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Dental Anxiety
Testing of Cognitive Behavioral Therapy Resource of Turkish Version
This study aimed to evaluate the cognitive behavioral therapy source of Turkish version of the 'message to dentist' (MTD) with children attending two dental settings.
- Trial name
- NCT05285722
- Testing
- Cognitive Behavioral Therapy form for dental anxiety
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- Altinbas University