Clinical trials: Cognitive Measures, active
Healthy
A Study of TopSpin360 Training Device
This research is being done to investigate the novel neck strengthening device, TopSpin360 and its effectiveness on measures of neck strength and cognitive function.
- Trial name
- NCT06052553
- Testing
- TopSpin360
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Rheumatoid Arthritis
STudying Ageing in Rheumatic Diseases (STAR)
The primary objective of the STAR study is to investigate how measures of disease activity and measures for cognition, physical activity and performance behave in ageing population controls and patients with rheumatoid arthritis…
- Trial name
- NCT05463666
- Testing
- Rheumatoid arthritis
- Where
- Netherlands
- Volunteers
- 840 people
- Sponsor
- Maastricht University Medical Center
Neurofibromatosis 1, Plexiform Neurofibromas
Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)
Background: People with neurofibromatosis 1 (NF1) who have plexiform neurofibromas (pNFs) can have pain that affects their daily lives.
- Trial name
- NCT02544022
- Where
- 6 sites in United States
- Volunteers
- 476 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute (NCI)
Healthy Adult, Cognitive Measures
Multivitamin Intervention and Cognitive Function
The purpose of this trial is to learn how a multivitamin combined blueberry polyphenol supplement (Vitals+) influences cognitive function in healthy adults.
- Trial name
- NCT06795789
- Testing
- Vitals+ (combined multivitamin and polyphenol supplement)
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Braincare Limited
Acute Kidney Injury, Exertional Heat Illness
Effects of Creatine Supplementation on Cognitive Measures and Markers of Acute Kidney Injury After Exercise in the Heat
The goal of this clinical trial is to learn if one week of creatine monohydrate supplementation alters inflammation, markers of acute kidney injury (AKI) risk, and cognitive performance in active, young, healthy volunteers.
- Trial name
- NCT07472426
- Testing
- Creatine Monohydrate
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Northern Iowa
Cognitive Decline
Study Evaluating the Quality and Effects of Lion's Mane Product on Cognitive Health
The rationale for this study is to observe differences in cognitive health outcomes such as short term memory and simple reaction time between a consumer-grade and commercially available Lion's mane mushroom product and a placebo…
- Trial name
- NCT06870136
- Testing
- Lion's Mane Study Product
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- M2 Ingredients
Parkinson Disease
TMS-related Measures as Biomarker of Cognitive Impairment in PD
The goal of the present study is to explore the diagnostic and prognostic value of neurophysiological biomarkers obtained through paired-pulse Transcranial Magnetic Stimulation (TMS) techniques in individuals affected by…
- Trial name
- SAI-PD22 (NCT06835595)
- Testing
- Transcranial Magnetic Stimulation
- Where
- 3 sites in Italy
- Volunteers
- 52 people
- Sponsor
- Azienda Sanitaria Universitaria Integrata del Trentino
Autism Spectrum Disorder (ASD), Anxiety
Adapted Group Therapy Compared With Usual Care for Anxiety and Depression in Adults With an Autism Diagnosis
The goal of this clinical trial is to learn whether an adapted group therapy works to treat anxiety and depression in adults with an autism diagnosis. The therapy is a form of cognitive behavioral therapy (CBT).
- Conditions
- Autism Spectrum Disorder (ASD), Anxiety, Depression
- Trial name
- CoMind (NCT07880028)
- Testing
- Autism-adapted group cognitive behavioral therapy
- Volunteers
- 154 people
- Sponsor
- Lovisenberg Diakonale Hospital
Liver Cirrhosis, Cognitive Dysfunction
The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)
The goal of this observational study is to develop and test a new questionnaire called the Liver Cirrhosis Cognitive Decline Scale (LiCCoS) for adults with liver cirrhosis.
- Conditions
- Liver Cirrhosis, Cognitive Dysfunction, Hepatic Encephalopathy, Neurocognitive Disorders
- Trial name
- LiCCoS (NCT07418008)
- Where
- India
- Volunteers
- 230 people
- Sponsor
- University of Malaya
Multiple Sclerosis
Assessing the Effects of Ongoing Ocrelizumab (OCR) Therapy on Fatigue and Cognition in Veterans With Multiple Sclerosis
This study seeks to assess the effects of long-term ocrelizumab therapy on fatigue (extreme tiredness) as well as cognition (thinking and reasoning skills, such as memory, learning and attention), in veterans with multiple…
- Trial name
- ML45855 (NCT07181811)
- Testing
- Multiple Sclerosis patients who have been on Ocrelizumab will undergo cognitive and fatigue assessments
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anza Memon
Deconditioning, Orthopedic Fractures
This Study Aims to Measure the Effect of Acute Hospitalisation on the Physical and Cognitive Functioning of Older Orthopaedic Patients (Aged 65 or Above).
This study aims to investigate the impact of hospitalisation on physical and cognitive performance in patients aged 65 and older admitted with an orthopaedic injury.
- Conditions
- Deconditioning, Orthopedic Fractures, Hospital Associated Deconditioning, Orthopaedic Injuries
- Trial name
- NCT06932224
- Where
- United Kingdom
- Volunteers
- 70 people
- Sponsor
- University of Southampton
Clinical High Risk for Psychosis (CHR)
A Study Exploring Changes in a Variety of Biomarkers Following Dosing With MT1988 in Participants at Clinical High Risk for Psychosis
The goal of this clinical trial is to learn how tests undertaken by people at high risk of developing psychosis (aged 17 to 30 years old) change when those people are given the study drug MT1988 daily for 8 weeks.
- Trial name
- NCT07226895
- Testing
- MT1988 Low Dose, MT1988 High Dose
- Where
- 15 sites in United States
- Volunteers
- 150 people
- Sponsor
- Monument Therapeutics Limited
Post Intensive Care Syndrome (PICS)
Post Intensive Care Accelerometery to Study and Support Recovery Outcomes
The primary purpose of this study is to find out whether a wrist-worn activity monitor can help healthcare professionals understand how people recover after they leave the intensive care unit (ICU), where they were cared for when…
- Trial name
- PICASSO (NCT07466446)
- Where
- 3 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Sleep, Cardiovascular Diseases
Effects of Milk-based Drinks on Gut Microbiome, Sleep and Cardiometabolic Markers
The purpose of this study is to evaluate the effects of kefir on gastrointestinal health, sleep quality, and biochemical parameters in adults who have sleep problems.
- Conditions
- Sleep, Cardiovascular Diseases, Gut Microbiome, Cognitive Function and Mood
- Trial name
- NCT07071181
- Testing
- Original flavour kefir, Milk
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
MCI, Mild Cognitive Impairment (MCI)
Prevalence of Mild Cognitive Impairment and Dementia in Patients Admitted to Non-neurological Rehabilitation Wards
Cognitive impairment is common among older adults hospitalized for non-neurological conditions but often goes unrecognized, particularly in rehabilitation settings where clinical attention is mainly focused on physical recovery.
- Conditions
- MCI, Mild Cognitive Impairment (MCI), Mild Cognitive Impairment, Cognitive Deficit
- Trial name
- COGinREHAB (NCT07731334)
- Testing
- Cognitive and clinical screening, Extended neuropsychological assessment, Blood biomarker sampling and APOE genotyping
- Where
- 3 sites in Italy
- Volunteers
- 384 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Alzheimer Disease and Related Dementias, Cognition
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
The objective of this study is to determine the effects of a 6-month, home-based personalized transcranial direct current stimulation (tDCS) intervention targeting the left dorsolateral prefrontal cortex on cognitive function…
- Conditions
- Alzheimer Disease and Related Dementias, Cognition, Mobility Disability
- Trial name
- TDCS4MCR (NCT06821568)
- Testing
- Personalized Transcranial Direct Current Stimulation (tDCS)
- Where
- 2 sites in United States, Israel
- Volunteers
- 128 people
- Sponsor
- Hebrew SeniorLife
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University