Clinical trials: Cognitive Fatigue
Rheumatoid Arthritis, Pain
Effect of Antiinflammatory Treatment Versus Hand Training on Neuropsychiatric Comorbidity in RA-patients
The purpose of this study is to investigate how RA affect the brain structures in RA-patients and if anti-inflammatory treatment that target TNF-α or JAK OR physical training of hands has positive impact on neuropsychiatric…
- Conditions
- Rheumatoid Arthritis, Pain, Fatigue, Cognitive Decline
- Trial name
- NeuMRA (NCT04378621)
- Testing
- TNF-α inhibitor OR JAK inhibitor, Hand training
- Where
- Sweden
- Volunteers
- 212 people
- Sponsor
- Vastra Gotaland Region
Breast Cancer Female, Side Effects
Rehabilitation Through Hippotherapy for the Management of Women After Primary Treatment of Breast Cancer
Breast cancer is the most common women's cancer and the third leading cause of death. Advances in prevention, detection and primary treatment have improved overall survival leading to its growing acceptance as a long-term…
- Conditions
- Breast Cancer Female, Side Effects, Psychological Distress, Physical Disability
- Trial name
- HippoBreastCa (NCT04350398)
- Testing
- Hippotherapy, Conventional therapy
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Alliance Equiphoria
Psychological Adaptation, Cognitive Change
Health Psychological Group Rehabilitation for Patients With Chronic Fatigue Syndrome (ME/CFS)
Chronic fatigue syndrome (ME/CFS) is a severe medical condition. It is characterized by long term fatique and other persisted symptoms, such as a cognitive disabilities and orthostatic intolerance.
- Conditions
- Psychological Adaptation, Cognitive Change, Adaptive Behavior, Functioning
- Trial name
- NCT04151693
- Testing
- Health Psychological Group Rehabilitation for Patients With Chronic Fatigue Syndrome (ME/CFS)
- Where
- Finland
- Volunteers
- 80 people
- Sponsor
- Joint Authority for Päijät-Häme Social and Health Care
Brain and Central Nervous System Tumors, Cognitive/Functional Effects
Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors
RATIONALE: Methylphenidate may decrease side effects of radiation therapy. It is not yet known if methylphenidate is effective in improving quality of life in patients with primary or metastatic brain tumors.
- Conditions
- Brain and Central Nervous System Tumors, Cognitive/Functional Effects, Depression, Fatigue
- Trial name
- NCT00031798
- Testing
- methylphenidate hydrochloride, quality-of-life assessment, radiation therapy
- Where
- 7 sites in United States
- Sponsor
- Wake Forest University Health Sciences
Brain Tumor
Systematic Light Exposure in Pediatric Brain Tumor Survivors
Children and adolescents treated for a brain tumor often experience fatigue and cognitive symptoms, such as slowed information processing and inattention.
- Trial name
- SLEPBT (NCT05340881)
- Testing
- Bright Light Exposure, Dim Light Exposure, Cognitive Assessment
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Baylor College of Medicine
Chronic Fatigue Syndrome
A Rehabilitation Program for Adolescents With Chronic Fatigue Syndrome
The aim of the programme is to develop a treatment model for adolescents with Chronic Fatigue Syndrome. The program consists of 4 elements lasting for 12 months, psychoeducation reflecting the current knowledge about the disease…
- Trial name
- NCT01806246
- Testing
- integrative rehabilitation program
- Where
- Norway
- Volunteers
- 13 people
- Sponsor
- St. Olavs Hospital
Cognitive Fatigue, Mental Fatigue
Effects of Natural Sounds on Attention Restoration in Virtual Reality
This study aims to examine whether listening to natural sounds in a noisy virtual reality environment compared to no natural sounds influences physiological markers.
- Conditions
- Cognitive Fatigue, Mental Fatigue, Behavioral Performance, Heart Rate Variability
- Trial name
- VEARS (NCT05679869)
- Testing
- Masking Sound, No masking sound
- Where
- Singapore
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nanyang Technological University
Sensory Science, Performance Assessment
Personalized Performance Optimization Platform
Crews of future long-duration exploration missions will have to cope with a wide range of stressors that present significant challenges for maintaining optimal performance.
- Conditions
- Sensory Science, Performance Assessment, Countermeasure Evaluation, Neurocognitive Function
- Trial name
- P-POP (NCT06979570)
- Testing
- AttentivU
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Anxiety, Cancer Survivor
Mindfulness Intervention in Reducing Anxiety in Patients Who Have Been Treated for Gynecologic Cancer
This pilot clinical trial studies how well a mindfulness-based stress reduction (MBSR) intervention works in reducing anxiety in patients who have undergone treatment for gynecologic cancer but no longer have any sign of disease.
- Conditions
- Anxiety, Cancer Survivor, Cognitive Impairment, Depression
- Trial name
- NCT02518308
- Testing
- Mindfulness-Based Stress Reduction
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- University of Wisconsin, Madison
Burnout, Professional
Decision Fatigue and Emotional Exhaustion Among Anesthesiologists
This study aims to evaluate the level of decision fatigue among anesthesiologists actively practicing in clinical settings in Turkey and to examine its relationship with emotional exhaustion.
- Trial name
- NCT07089160
- Testing
- Online Survey (Decision Fatigue Scale and Emotional Exhaustion Scale)
- Where
- Turkey (Türkiye)
- Volunteers
- 97 people
- Sponsor
- Istinye University
COVID-19, Brain Fog
Transcranial Ultrasound Stimulation for Cognitive Function Modulation in Patients With Post COVID-19 Brain Fog
This study aims to investigate whether a specific brain region mediates the cognitive deficit in long COVID brain fog, and whether targeted modulation of this region can improve cognition.
- Conditions
- COVID-19, Brain Fog, Long COVID, Transcranial Ultrasound Stimulation
- Trial name
- NCT07154199
- Testing
- real transcranial ultrasound stimulation
- Where
- 2 sites in China
- Volunteers
- 40 people
- Sponsor
- Xuanwu Hospital, Beijing
Multiple Sclerosis, Insomnia
Comparing Telehealth-Delivered CBT-I to Web-Based CBT-I to Enhance Sleep, Reduce Fatigue, and Promote Neuroprotection
The objective of this RCT is to assess the efficacy of one-on-one telehealth CBT-I (tCBT-I) compared to web-based CBT-I (wCBT-I) and treatment as usual (TAU) to improve sleep outcomes (Aim 1), fatigue and quality of life (Aim 2)…
- Trial name
- CLEAR (NCT06434571)
- Testing
- Telehealth cognitive behavioral therapy for insomnia (tCBT-I), Web-based cognitive behavioral therapy for insomnia (wCBT-I), Treatment as usual (TAU)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- University of Kansas Medical Center
Brain Tumors, Nervous System Tumors
Armodafinil in Treating Fatigue Caused By Radiation Therapy in Patients With Primary Brain Tumors
RATIONALE: Armodafinil may help relieve fatigue and improve quality of life in patients with cancer receiving radiation therapy to the brain.
- Conditions
- Brain Tumors, Nervous System Tumors, Cognition Disorders, Fatigue
- Trial name
- NCT01032200
- Testing
- Armodafinil
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Wake Forest University Health Sciences
Multiple Sclerosis
Assessing the Effects of Ongoing Ocrelizumab (OCR) Therapy on Fatigue and Cognition in Veterans With Multiple Sclerosis
This study seeks to assess the effects of long-term ocrelizumab therapy on fatigue (extreme tiredness) as well as cognition (thinking and reasoning skills, such as memory, learning and attention), in veterans with multiple…
- Trial name
- ML45855 (NCT07181811)
- Testing
- Multiple Sclerosis patients who have been on Ocrelizumab will undergo cognitive and fatigue assessments
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Anza Memon
Fibromyalgia
Subjective Ageing in Fibromyalgia
Subjective age or felt age is the term used for how the person feels; one can feel same, younger or older than their actual age.
- Trial name
- NCT03966820
- Where
- Turkey (Türkiye)
- Volunteers
- 262 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Cognitive Dysfunction, Acquired Brain Injury
Fareon Open Label Device Clinical Trial
The purpose of this study is to assess the safety and feasibility of an at-home MMT treatment in patients with cognitive dysfunction related to acquired brain injury, Long COVID, traumatic brain injury, myalgic encephalomyelitis…
- Conditions
- Cognitive Dysfunction, Acquired Brain Injury, Traumatic Brain Injury
- Trial name
- NCT07600320
- Testing
- Fareon device
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cognition, Mood
Investigation of the Acute Effects of Nepalese Pepper Extract (Zanthoxylum Armatum DC) on Cognitive Function, Mood and Gaming Performance in Young, Healthy, Competitive Gamers
The goal of this clinical trial is to learn if a Nepalese Pepper Extract (Zanthoxlum Armatum, ZA) supplement can improve cognitive performance and mental abilities in competitive gamers aged 16 to 34.
- Conditions
- Cognition, Mood, Gaming Performance, Fatigue
- Trial name
- NCT07047105
- Testing
- Nepalese Pepper (Zanthoxylum Armatum) extract 150mg, Nepalese Pepper (Zanthoxylum Armatum) extract 300mg, Caffeine 75mg
- Where
- United Kingdom
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Arthritis, Fatigue
Tablet-based Cognitive Behavioral Intervention for Older Adults With Arthritis Fatigue
The purpose of this project is to pilot test a long-term effect of Tab-G (tablet-based cognitive behavioral group education intervention).
- Trial name
- NCT04792853
- Testing
- Tab-G
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Massachusetts, Amherst
Inflammation, Fatigue
Effects of Riluzole on CNS Glutamate and Fatigue in Breast Cancer Survivors With High Inflammation
The goal of the proposed research is to determine whether riluzole, a drug that increases glutamate reuptake, will decrease central nervous system (CNS) glutamate in breast cancer survivors with increased inflammation and…
- Trial name
- NCT02796755
- Testing
- Riluzole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Emory University
Stress Perception, Psychological Resilience, Compassion Fatigue
Evaluation of the Effect of Cognitive Behavioral Approach-Based Stress Coping Skills Training Program on Stress Perception, Resilience and Compassion Fatigue
This research is an experimental study with a randomized pre-test-post-test control group to evaluate the effect of the cognitive behavioral approach-based stress coping skills training program carried out by tele-nursing on the…
- Trial name
- NCT05830448
- Testing
- Cognitive Behavioral Therapy, T.R. Mobile Mental Health Support System produced by the Ministry of Health
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Eskisehir Osmangazi University