Clinical trials: Cognitive Fatigue
Quality of Life (QOL), Communication Barriers
The Mental Cost and Burden of Listening
This randomised controlled trial aims to test the effect of hearing adjustment using hearing aids, on the ease and effectiveness of communication such as listening effort, fatigue, and sentence recognition in noise, in addition…
- Conditions
- Quality of Life (QOL), Communication Barriers, Cognitive Performance, Fatigue, Mental
- Trial name
- NCT06951815
- Testing
- Hearing aids programmed to each participant's hearing loss.
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Cognitive Function, Balance Impairment
Effects of Action Observation Therapy in Geriatric Individuals
This randomized controlled trial aimed to investigate the effects of Action Observation Therapy (AOT) on cognitive function, balance, fatigue, and functional capacity in geriatric individuals.
- Conditions
- Cognitive Function, Balance Impairment, Fatigue, Aging
- Trial name
- NCT07418970
- Testing
- Action, Action Observation Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 162 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Psychological Stress, Mental Fatigue
Psychophysiological Effects of Green Exercise in Outdoor Green vs. Indoor Control
Core Purpose: Researchers want to learn if walking in an outdoor green environment helps people recover from mental tiredness and stress better than walking indoors.
- Conditions
- Psychological Stress, Mental Fatigue, Cognitive Dysfunction, Emotional Well-being
- Trial name
- GREEN-OI (NCT07379164)
- Testing
- Outdoor Green Group, Indoor Control Group
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Lincoln University College
CAR T Cell Therapy, ICANS
Neurological and Cognitive Dysfunction Following CAR-T Treatment. ICANS and Beyond
This is a phase 4 non-interventional single center trial. We aim to prospectively include patients scheduled to undergo CAR-T therapy at ME CAST, Karolinska University Hospital Huddinge, to study ICANS.
- Conditions
- CAR T Cell Therapy, ICANS, Cognitive and Executive Dysfunction
- Trial name
- NCT07375628
- Volunteers
- 10 people
- Sponsor
- Karolinska University Hospital
Fatigue, Graft Vs Host Disease
Fatigue and Cognitive Dysfunction Due to Synaptopathy or Graft Versus Host (GVH) Disease in the Brain.
Patients undergoing allogenic stem cell transplantation are regularly followed up in the outpatient clinic at Karolinska University Hospital.
- Conditions
- Fatigue, Graft Vs Host Disease, Cognitive Dysfunction
- Trial name
- NCT07365696
- Testing
- PET investigation
- Where
- Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
Cognitive Assessment, Working Memory
Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure.
The proposed project will evaluate the synergistic effects of a nutritional formulation, 'Think Tank' on cognitive performance following exposure to a psychological and physical stressor.
- Conditions
- Cognitive Assessment, Working Memory, Executive Function (Cognition), Sustained Attention
- Trial name
- NCT07319117
- Testing
- Skoshify 'Think Tank' Formulation
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Leeds Beckett University
Brain Fog, Cognitive Health
Modulation of the Brain Fog Scale by Eicosapentaenoic Acid Monoglycerides (MAG-EPA).
A growing body of studies shows that omega-3s act directly in molecular signaling pathways that reduce inflammation and are thought to have a positive effect on cognitive health.
- Trial name
- NBF-MG01 (NCT06695910)
- Testing
- Monoglyceride Eicosapentaenoic acid (omega-3), Sunflower Oil
- Where
- 2 sites in Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Samuel Fortin
Chronic Rhinosinusitis, Sleep Disorders
Sleep Disturbance and Daytime Fatigue as Predictors of Cognitive Decline and Functional Decline in Chronic Rhinosinusitis
FOCUS-CRS is a cross-sectional observational study examining the relationship between sleep disturbance, daytime fatigue, and cognitive and functional health in patients with chronic rhinosinusitis (CRS).
- Conditions
- Chronic Rhinosinusitis, Sleep Disorders, Fatigue, Cognitive Dysfunction
- Trial name
- SNOOZE-CRS (NCT07242040)
- Testing
- Self-Reported Questionnaires for Sleep, Fatigue, and Quality of Life
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- Sinai University
Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting
Sexual Dysfunction in Women With Multiple Sclerosis (MS)
Sexual dysfunction in women with multiple sclerosis (MS) is an important yet often overlooked problem. The primary objective of this study is to investigate the prevalence of sexual dysfunction in female patients diagnosed with…
- Conditions
- Multiple Sclerosis, Multiple Sclerosis (MS) - Relapsing-remitting, Fatigue in Multiple Sclerosis, Sexual Disfunction
- Trial name
- MS (NCT07193823)
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people
- Sponsor
- Ege University
COVID-19 (SARS-CoV-2 Infection)
Use of a Cysteine-rich Whey Protein Isolate in Post COVID-19 Cognitive Impairment
Abstract Background: Post-COVID-19 cognitive impairment (PCCI), characterized by deficits in attention, memory, and executive functioning, remains a major challenge among patients with long COVID.
- Trial name
- NCT07184398
- Testing
- Intervention with Consolidated Cysteine (Immunocal) 20 g per day, Cognitive rehabilitation workshops
- Where
- Colombia
- Volunteers
- 120 people
- Sponsor
- Universidad Libre seccional Cali
Type 2 Diabetes Mellitus (T2DM), Cognitive Function
Prediabetes and Type 2 Diabetes in Aging
This case-control study will evaluate the effects of geriatric individuals on cognitive status, physical function and fatigue. Our study aims to compare the effects of geriatric individuals with prediabetes and type 2 diabetes…
- Conditions
- Type 2 Diabetes Mellitus (T2DM), Cognitive Function, Dual Task, Fatigue
- Trial name
- NCT06953609
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Uşak University
Chronic Fatigue Syndrome, Cognitive Impairments
Efficacy and Safety of Lisdexamfetamine Dimesylate in Adults With Chronic Fatigue Syndrome
Over the past decade, the Rochester Center for Behavioral Medicine (RCBM) has evaluated many patients with attention deficit hyperactivity disorder (ADHD).
- Trial name
- NCT01071044
- Testing
- Lisdexamfetamine Dimesylate
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Rochester Center for Behavioral Medicine
Obstructive Sleep Apnea
Brain Fog in Sleep Apnea
Objective: This observational, cross-sectional pilot study aims to assess "Brain Fog" (cognitive symptoms impacting memory, attention, and concentration) in severe Obstructive Sleep Apnea (OSA) patients.
- Trial name
- BF -OSA (NCT06664450)
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Exercise Performance Impairment, Cognitive Function Decline
Effects of Energy Drink on Repeated Sprint Performance and Cognitive Function in Athletes
Energy drinks are often used by athletes before competitions to enhance their performance. Recent research has pointed out that the performance effects of select ingredients have been studied individually but not in combination…
- Conditions
- Exercise Performance Impairment, Cognitive Function Decline, Fatigue
- Trial name
- NCT07104188
- Testing
- Caffeine, Energy Drink
- Where
- Taiwan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Chien-Wen Hou
Brain Abscess, Fatigue
Cognitive Function and Fatigue After Brain Abscess
Brain abscess is a focal bacterial or fungal infection of the brain. Treatment is neurosurgical drainage of pus followed by long-term antibiotic treatment.
- Conditions
- Brain Abscess, Fatigue, Cognitive Dysfunction
- Trial name
- NCT04938362
- Testing
- FDG-PET, EEG
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University of Oslo
Menopause, Sleep Disturbance
Radicle Revive 24: A Study of Health and Wellness Products on Menopausal Health and Related Health Outcomes
A randomized, double-blind, placebo-controlled, direct-to-consumer trial assessing the impact of health and wellness products on hormonal health and associated health outcomes in women with menopausal health issues
- Conditions
- Menopause, Sleep Disturbance, Anxiety, Depression
- Trial name
- NCT06749288
- Testing
- Radicle Revive Active Study Product 4.1 Usage
- Where
- United States
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Radicle Science
Fatigue, Cognitive Load
Effects of Physical Fatigue on Cognitive Load and Performance Under Dual-Task Environments.
This study aims to determine how different levels of physical fatigue influence cognitive load and performance during dual-task activities. 1.
- Trial name
- NCT06941701
- Testing
- Mild-intensity physical fatigue, Moderate-intensity physical fatigue, High-intensity physical fatigue
- Where
- Pakistan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Cancer, Distress, Emotional
Cognitive Trance, Hypnosis and Meditation in Oncology
Patients with cancer often suffer from a symptom cluster, including pain, fatigue, sleep difficulties, emotional distress and cognitive impairments.
- Conditions
- Cancer, Distress, Emotional, Pain, Fatigue
- Trial name
- NCT04873661
- Testing
- Hypnosis group intervention, Cognitive trance group intervention, Meditation group intervention
- Where
- Belgium
- Volunteers
- 160 people
- Sponsor
- University of Liege
Cognitive Impairment, Old Age; Debility
Dietary Supplementation and Cognitive Functions in the Elderly
In recent years, globally, there has been a growth in both the size and the proportion of older adults in the world population. The World Health Organization (WHO) has estimated that by 2030, 1 in 6 people will be 60 years of age…
- Trial name
- ESPINS (NCT06352099)
- Testing
- Dietary supplement with micronised diosmin, hesperidin and herbal extracts
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Brain Fog
Transcranial Direct Current Stimulation (tDCS)
Cognitive impairment refers to when an individual struggles to learn, concentrate, remember, or make decisions. This can be due to underlying neurological diseases (i.e.
- Trial name
- tDCS (NCT05524233)
- Testing
- Active Transcranial Direct Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Baylor College of Medicine