Clinical trials: Cognitive Deficit
Breast Cancer Female, Side Effects
Rehabilitation Through Hippotherapy for the Management of Women After Primary Treatment of Breast Cancer
Breast cancer is the most common women's cancer and the third leading cause of death. Advances in prevention, detection and primary treatment have improved overall survival leading to its growing acceptance as a long-term…
- Conditions
- Breast Cancer Female, Side Effects, Psychological Distress, Physical Disability
- Trial name
- HippoBreastCa (NCT04350398)
- Testing
- Hippotherapy, Conventional therapy
- Where
- France
- Volunteers
- 83 people
- Sponsor
- Alliance Equiphoria
Down Syndrome
Application of LLM Care and Related Affective Computing Systems on Persons With Special Needs
Down syndrome (DS) is a genetic disorder characterized by specific physical characteristics (muscle degeneration) and cognitive phenotype (neurodegeneration caused by gene-overexpression that has affected memory, language, and…
- Trial name
- dsLLM (NCT04390321)
- Testing
- LLMcare
- Where
- Greece
- Volunteers
- 46 people
- Sponsor
- Aristotle University Of Thessaloniki
Huntington Disease
Non-invasive Brain Stimulation in Huntington's Disease
Huntington's disease is a disabling neurodegenerative disease. Patients present with involuntary movements of the body and cognitive symptoms like behavioral problem, difficulty in planning tasks, etc.
- Trial name
- NCT04429230
- Testing
- Active Transcranial pulsed current stimulation (tPCS)
- Volunteers
- 15 people
- Sponsor
- Western University, Canada
Mild Cognitive Impairment
Nurse-led Clinics Training Program on Mild Cognitive Impairment Patients
This trail is the first study to test the efficacy of nurse-led clinics cognitive training on mild cognitive impairment (MCI) patients using a single-blind, randomized controlled trial design.
- Trial name
- NCT06198530
- Testing
- cognitive training in NLCs, cognitive training in home, cognitive training in tradition
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Xuanwu Hospital, Beijing
Dementia
The Therapeutic Effect of Exercise Training on Patients With Dementia and Mild Cognitive Impairment
This study aimed to clarify whether strength training or aerobic training could bring more benefits for patients with dementia, another study is to clarify whether isokinetic or isotonic training could bring more benefits for…
- Trial name
- NCT03811314
- Testing
- Strength training, Aerobic training, Isokinetic trinaing
- Where
- Taiwan
- Volunteers
- 107 people
- Sponsor
- Taichung Veterans General Hospital
Childhood Hematopoietic and Lymphatic System Neoplasm, Childhood Malignant Solid Neoplasm
Strengthening Teen Brain Resilience Using Music Intervention to Improve Radiation Induced Cognitive Decline for Adolescents Undergoing Radiation Therapy for Cancer Treatment
This clinical trial tests the feasibility and acceptability of the Strengthening Teen Brain Resilience Using Music (STRUM) intervention to improve radiation induced cognitive decline for adolescents undergoing radiation therapy…
- Trial name
- NCT07729384
- Testing
- Interview, Music Therapy, Survey Administration
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Postoperative Cognitive Dysfunction
LINC01844 as a Diagnostic Biomarker for POCD in Elderly Patients
Postoperative cognitive dysfunction (POCD) is a common complication after surgery that is associated with more adverse events and death.
- Trial name
- NCT06387836
- Testing
- Isoflurane 0.8 MAC, Desflurane 0.8MAC
- Where
- China
- Volunteers
- 85 people
- Sponsor
- Shanghai Zhongshan Hospital
Cognitive Decline, Dementia Risk Factors
GOIZ ZAINDU Feasibility Multi Domain Trial to Prevent Dementia.
GOIZ ZAINDU ("caring early" in Basque) is a pilot study to adapt the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) methodology to the Basque population and evaluate feasibility and…
- Conditions
- Cognitive Decline, Dementia Risk Factors, Prevention, Multidomain Intervention
- Trial name
- GOIZ_ZAINDU (NCT06163716)
- Testing
- Multidomain intervention (MD-Int) group
- Where
- Spain
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Fundacion CITA-alzheimer
Cognitive Dysfunction
Neuropsychological Profile of a Patient's Group With Multiple Sclerosis and Effect of a Cognitive Rehabilitation Program
The purpose of the study is to determine the effect of an web-based intensive cognitive rehabilitation program in neuropsychological performance of a population of patients with multiple sclerosis or clinical isolated syndrome.
- Trial name
- MS_Rehab (NCT02193906)
- Testing
- Cognitive training
- Volunteers
- 75 people
- Sponsor
- Aveiro University
Cognitive Impairment, Mild, Dementia
Effects of Training Dose on Computerized Cognitive Training in Patients With Cognitive Impairment
The goal of this observational study is to explore the optimal dose of computerized cognitive training in patients with cognitive impairment.
- Trial name
- NCT05922319
- Testing
- Computerized cognitive training with different training doses
- Where
- China
- Volunteers
- 21,845 people
- Sponsor
- Xuanwu Hospital, Beijing
TBI Traumatic Brain Injury
DBS for Cognitive Deficits After Traumatic Brain Injury
Patients with memory and cognitive deficits following TBI that do not respond to conventional treatments experience a decrease in quality of life.
- Trial name
- NCT06818864
- Testing
- Deep Brain Stimulation
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Sunnybrook Health Sciences Centre
Covid19, Cognitive Impairment
Cognitive Training in Survivors of Covid-19: A Randomized Trial
Preliminary evidence suggests that cognitive impairment is a common outcome experienced by individuals surviving Covid-19 (1-5).
- Trial name
- NCT04956887
- Testing
- AKL-T01, Control Group
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Vanderbilt University Medical Center
Mild Cognitive Impairment
Effects of Tai Chi on Cognition, I-ADLs, and HRQOL in Older People With MCI
The prevalence of older people with cognitive decline is increasing since the aging population is growing substantially worldwide. Cognitive impairment places older adults at high risk for functional disability.
- Trial name
- NCT03404765
- Testing
- Tai Chi
- Where
- Hong Kong
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Mild Cognitive Impairment
Biodistribution of [11C]Acetoacetate/[18F]Fluorodeoxyglucose in Subjects With Risk Factors for Alzheimer's Disease
This is a single center imaging study that will recruit 60 participants who are enrolled in the Effect of a Ketogenic Diet on Alzheimer's Disease Biomarkers and Symptoms: Brain Energy for Amyloid Transformation in AD (BEAT-AD)…
- Trial name
- AcAc PET (NCT03130036)
- Testing
- [11C]Acetoacetate[18F]Fluorodeoxyglucose positron emission tomography scan
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Alzheimer Disease, Aging
Vanderbilt Memory and Aging Project
This study will use an observational cohort to cross-sectionally and longitudinally relate vascular health to clinical, imaging, and biological markers of early Alzheimer's disease and cerebrovascular disease among aging adults.
- Conditions
- Alzheimer Disease, Aging, Aged, 80 and Over, Biomarkers
- Trial name
- VMAP (NCT05372159)
- Testing
- none, observational study
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Vanderbilt University Medical Center
Treatment, Active Control
Cognitive Training Delivered Remotely to Individuals With Psychosis (ROAM)
Primary study: This study is a single-site, double-blind, randomized, controlled clinical trial to compare an evidence-based structured program of 30-35 hours of on-line cognitive and social cognitive training exercises performed…
- Conditions
- Treatment, Active Control, Schizophrenia, Psychosis
- Trial name
- NCT02782442
- Testing
- Structured Cognitive Training & PRIME, Computer Games Control & PRIME
- Where
- 2 sites in United States
- Volunteers
- 109 people
- Sponsor
- University of Minnesota
Alzheimer Disease
Alzheimer's Disease - Input of Vitamin D With mEmantine Assay
The purpose of this study is to compare the effect after 24 weeks of the oral intake of vitamin D3 (cholecalciferol) with the effect of a placebo on the change of cognitive performance in patients suffering from moderate…
- Trial name
- AD-IDEA (NCT01409694)
- Testing
- Memantine, Vitamin D
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Angers
Alzheimer's Disease
Practice Effects and Amyloid Imaging Using 18F-PIB or Flutemetamol PET and FDG-PET
Alzheimer's disease (AD) is the most common cause of progressive cognitive decline in the United States. AD is characterized by severe impairments in learning, memory and other cognitive abilities that significantly interfere…
- Trial name
- NCT01202994
- Testing
- 18F-Flutemetamol
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Utah
Major Depressive Disorder, Cognitive Dysfunction
Musical Attention Control and Executive Function Training for Adults With MDD
The investigators have developed music-based cognitive training sessions derived from Neurologic Music Therapy (NMT) techniques.
- Conditions
- Major Depressive Disorder, Cognitive Dysfunction, Suicide
- Trial name
- NCT05694156
- Testing
- Music-based cognitive training
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- Unity Health Toronto
Intrinsic Capacity, Frailty
Project ICOPE Brazil: Assessment of Intrinsic Capacity in Brazilian Older Adults
The ICOPE Brazil study aims to understand aging trajectories in Brazil, especially healthy aging trends based on intrinsic capacity, a collective of mental and physical capacities one may have to maintain their functional ability…
- Conditions
- Intrinsic Capacity, Frailty, Aging, Healthy Aging
- Trial name
- ICOPE-BR (NCT06968702)
- Volunteers
- 3,838 people
- Sponsor
- University of Sao Paulo