Clinical trials: Cognitive Ability
Cognitive Function
The Cognitive Functioning of Young Athletes Including Bioelectrical Brain Function
The project focuses on two central issues: 1. The impact of intensity of sport on the cognitive functioning and brain waves of children in late childhood (10-12 years old); 2.
- Trial name
- NCT04753047
- Testing
- No intervention
- Where
- 2 sites in Poland
- Volunteers
- 179 people, healthy volunteers welcome
- Sponsor
- University of Gdansk
Pathologically Confirmed Differentiated Thyroid Carcinoma, All Patients Are in the Initial Treatment Phase
The Effect of a Psychosomatic Symptom Intervention Program on the Primary Treatment of Differentiated Thyroid Cancer
The psychosomatic symptoms of patients with differentiated thyroid cancer (DTC) during the initial treatment phase need to be improved.
- Conditions
- Pathologically Confirmed Differentiated Thyroid Carcinoma, All Patients Are in the Initial Treatment Phase, Normal Cognitive and Communicative Abilities, Capable of Reading and Understanding Questionnaires in Chinese, Ability to Use a Smartphone
- Trial name
- NCT06422702
- Testing
- Psychosomatic Symptoms Intervention, Extended supportive care
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Harbin Medical University
Healthy
Effect of a Nutritional Approach in Combination With Cognitive Stimulation on Child Cognitive Abilities
The objective of the study is to explore the impact of a combined intervention including a growing up milk (GUM) fortified in micronutrients and cognitive stimulation on cognitive abilities, mother-child- interaction and behavior…
- Trial name
- Stimulearn (NCT02359669)
- Testing
- StimuLearn Intervention, Without StimuLearn intervention
- Where
- Indonesia
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Cardiovascular Diseases, Heart Diseases
Age, Risk Factors for CVD and Cognitive Functioning
To relate cardiovascular disease (CHD) risk factors to cognitive performance among middle-aged and elderly men and women over a 10 year longitudinal study period.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Neurologic Manifestations
- Trial name
- NCT00007397
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Friedreich's Ataxia, Motor Disorders
Electroencephalogram in Patients With Friedreich's Ataxia for the Study of the Structural and Functional Connectome.
Prospective, exploratory, multicenter pilot study investigating the structural and functional connectome in patients with Friedreich's Ataxia (FRDA) using high-density electroencephalogram (HD-EEG).
- Trial name
- CONNETTOMA (NCT07095062)
- Testing
- HD-EEG recordings, combined with cognitive and motor assessment
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Eugenio Medea
Neurodegenerative Diseases, Cognition Disorders in Old Age
Probiotics in Mild Alzheimer's Disease
The main objective is to investigate whether administration of probiotics to patients with mild Alzheimer's Disease (AD) reduces neuroinflammation, improves cognitive function and modifies neurophysiological measures, compared to…
- Trial name
- NCT06181513
- Testing
- Probiotic Blend Capsule
- Where
- Cyprus
- Volunteers
- 40 people
- Sponsor
- University of Nicosia
Functional Abilities, Cognitive Abilities
Effect of Instrument-assisted Soft Tissue Mobilization on Functional and Cognitive Abilities in Elderly
PURPOSE: To determine the effect of Instrument-assisted soft tissue mobilization on functional and cognitive abilities in elderly. BACKGROUND: There is an increased interest in health care with growth of the older population.
- Trial name
- IASTM-AGE (NCT07208630)
- Testing
- Instrument-assisted soft tissue mobilization, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dementia in Nursing Home
Cognitive Stimulation Therapy for Residents With Dementia in Nursing Homes
The goal of this experimental study was to evaluate whether cognitive stimulation therapy (CST) improved cognitive functioning and engagement levels in individuals with mild-to-moderate dementia residing in long-term care…
- Trial name
- NCT06978972
- Testing
- Cognitive Stimulation Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Northern Kentucky University
Mild Cognitive Impairment
Neurobic Exercise Program on Cognitive Abilities
This research aims to investigate the significance of a neurobic exercise program on cognitive abilities, memory retention, activities of daily living (ADL), and quality of life (QOL) among older adults with mild cognitive…
- Trial name
- NCT06601751
- Testing
- Neurobic Exercise Program, Traditional Brain Exercise
- Where
- Pakistan
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Old Age; Debility
Puzzle Game Strategy on Older Adults
One innovative approach uses puzzle game strategies, including crosswords, Sudoku, and other brain-teasing activities. These strategies have been shown to help maintain attention, improve memory, and keep older adults' thoughts…
- Trial name
- PUZZLEOLDER (NCT06459492)
- Testing
- puzzle game strategies
- Where
- Egypt
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Smoke Exposure, Smokeless Tobacco
Effect of Passive Smoking on Functional Capacity, Cognition and Academic Performance in Primary School Children
This is an observational study that aims to understand the effects of passive smoking (secondhand smoke exposure) on children's health and development.
- Trial name
- NCT06723470
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Egyptian Chinese University
Autism Spectrum Disorder (ASD)
Omega-3 Fatty Acids Monotherapy in Children and Adolescents With Autism Spectrum Disorders
The primary aim of this study is to examine the efficacy and tolerability of short-term omega-3 fatty acids monotherapy in youth with Autism Spectrum Disorders (ASD).
- Trial name
- NCT01248130
- Testing
- Omega-3 Fatty Acid
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Massachusetts General Hospital
Multiple Sclerosis
Electrical Brain Stimulation for Treatment of Secondary Symptoms in Multiple Sclerosis
Multiple Sclerosis (MS) is an autoimmune disease associated with physical disability, psychological impairment, and cognitive dysfunction. As a result, the disease burden is high, and treatment options are limited.
- Trial name
- NCT06401928
- Testing
- transcranial direct current stimulation, transcranial direct current stimulation combined with cognitive training
- Where
- Iran
- Volunteers
- 53 people
- Sponsor
- The National Brain Mapping Laboratory (NBML)
Right Hemispheric Stroke, Left Hemispheric Stroke
Neural and Cognitive Correlates of Pragmatic Abilities
Pragmatics of language refers to the set of abilities that allow one to use and interpret language according to context and, in general, to communicate effectively.
- Conditions
- Right Hemispheric Stroke, Left Hemispheric Stroke, Traumatic Brain Injury, Right Hemispheric Brain Tumor
- Trial name
- APACS_Neuro (NCT06297044)
- Testing
- Neuropsychological assessment
- Where
- Italy
- Volunteers
- 324 people, healthy volunteers welcome
- Sponsor
- IRCCS San Camillo, Venezia, Italy
Borderline Intellectual Functioning (BIF)
A Comparative Study of Virtual Reality and Sensory-Adapted Dental Environments for Dental Anxiety Reduction in Individuals With BIF
A randomized clinical trial was conducted with 98 participants with borderline intellectual functioning (BIF) and moderate dental anxiety (DAS: 9-12).
- Trial name
- VR-SADE (NCT07261670)
- Testing
- Virtual Reality Distraction - immersive VR software delivered through Meta Quest 3® headset during dental procedure, Sensory adapted dentist environment
- Where
- Italy
- Volunteers
- 98 people
- Sponsor
- Oasi Research Institute-IRCCS
Healthy
Explore the Nature Factors Relevant to Learning-Pioneering Natural Factors That Influences Science Learning II
Genetic research has provided the most exciting breakthroughs in neuroscience and cognitive science. Partially genetically determined cognitive impairments have been described in people with COMT, 5HT6, BDNF (Swillen et al.…
- Trial name
- NCT00713570
- Where
- Taiwan
- Volunteers
- 2,800 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Parkinson's Disease, Freezing of Gait
Study to Assess the Clinical Benefit and Safety of Droxidopa in Parkinson's Disease
Since droxidopa has been approved in Japan for treating freezing of gait in Parkinson's disease patients, this is to confirm and further investigate the safety and efficacy using a similar dose.
- Conditions
- Parkinson's Disease, Freezing of Gait, Cognitive Ability, General
- Trial name
- NCT02066571
- Testing
- Droxidopa, sugar pill
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Traumatic Brain Injury
NeuroAiD II™ (MLC901) in Mild Traumatic Brain Injury
A Randomized Double-blind, Placebo-controlled, Multi-center Trial to determine the efficacy of NeuroAiD II™ (MLC901) in improvement of cognitive functioning of adult patients with long-term cognitive impairment following mild…
- Trial name
- SAMURAI (NCT04861688)
- Testing
- Traditional Chinese Medicine (NeuroAiD II™ (MLC901)
- Where
- 4 sites in Russia
- Volunteers
- 182 people
- Sponsor
- Moleac Pte Ltd.
Prostate Cancer
Predicting Cognitive Decline From Androgen Deprivation Therapy
Androgen Deprivation Therapy (ADT) is associated with cognitive impairment and dementia in men with prostate cancer. Pre-clinical data suggest that ADT-induced hypogonadism leads to accumulation of beta-amyloid plaques in the…
- Trial name
- ABC (NCT05820932)
- Testing
- Blood-based assay, Cognitive assessments, Quality of Life Surveys
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, San Francisco
Schizophrenia, Schizoaffective Disorder
Therapeutic Improvement in People With Schizophrenia Undergoing tACS/CBTp (Transcranial Alternating Current Stimulation Applied Pre-cognitive Behavioral Therapy for Psychosis) Associated to Usual Medication Regimen
The investigators are proposing a new, non-invasive therapeutic model using transcranial alternative current stimulation (tACS), to augment cognitive behavioral therapy for psychosis (CBTp) efficacy in individuals with…
- Trial name
- tACS/CBTpSZ (NCT06889025)
- Testing
- Experimental: tASC/CBTp: gamma band electric stimulation for 20 minutes at the beginning of the CBTp session
- Where
- Canada
- Volunteers
- 28 people
- Sponsor
- Felicia Iftene