Clinical trials: Coenzyme q10, open to volunteers
Frailty, Aging
MItochondrial Intervention for Resilience in Older Adults With Coenzyme Q10
This randomized, double-blind, placebo-controlled clinical trial will investigate whether 10 weeks of CoQ10 supplementation can improve biological resilience and functional health in community-dwelling adults aged 65 years or…
- Conditions
- Frailty, Aging, Mitochondria Health, Skin Aging
- Trial name
- MIRO-Q (NCT07772336)
- Testing
- Q10Vital® (CoQ10, ubiquinone)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Periodontal Diseases, Pregnancy Related
Adjunctive Periodontal Treatment With Coenzyme Q10 in Association With Probiotics for Pregnant Women
The aim of the study is to assess if probiotic supplementation can be effective in reducing periodontal clinical parameters in a 6-month study on pregnant patients.
- Trial name
- NCT06308497
- Testing
- Probiotic Treatment, Standard Treatment
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Cardiovascular Disease (CVD), Elevated Cardiovascular Risk
Sacha Inchi-CoQ10 Supplementation and Cardiovascular Health
The goal of this clinical trial is to learn if Sacha Inchi-CoQ10 supplementation can improve cardiovascular health in adults who have an increased risk of cardiovascular disease.
- Conditions
- Cardiovascular Disease (CVD), Elevated Cardiovascular Risk, Endothelial Dysfunction
- Trial name
- Sacha-Q10 (NCT07792005)
- Testing
- Sacha-Q10 Plus
- Volunteers
- 60 people
- Sponsor
- Hospital Pengajar Universiti Putra Malaysia
Coenzyme Q10, Alveolar Cleft Grafting
Effect of Co-enzyme Q10 on the Bone Volume of Alveolar Cleft Reconstruction
Evaluate the effect of Co-enzyme Q10 on the bone volume in unilateral alveolar cleft repair
- Trial name
- NCT07045246
- Testing
- Coenzyme Q 10, iliac bone graft
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Fayoum University
Asthenozoospermia
Effect of Pentoxifylline + CoQ10 vs CoQ10 Alone on Sperm Motility in Subfertile Men With Asthenozoospermia
The goal of this clinical trial is to learn if drug Pentoxifylline plus Coenzyme Q10 work to treat asthenozoospermia in subfertile male. It will also learn about the safety of drug Pentoxifylline plus Coenzyme Q10.
- Trial name
- NCT07252518
- Testing
- Coenzyme Q 10, Pentoxifylline 400 MG Oral Tablet
- Where
- Bangladesh
- Volunteers
- 56 people
- Sponsor
- Mst.Sumyara Khatun
Hypercholesterolemia, Lipid Metabolism Disorders
Metabolic Effects of an Ophiocordyceps Sinensis- and CoQ10-Based Formulation in Mild-to-Moderate Hypercholesterolemia
This randomized, double-blind, placebo-controlled study will evaluate the metabolic effects of CORDICOL, a formulation containing Ophiocordyceps sinensis extract (200 mg) and Coenzyme Q10 (50 mg), in adults with mild-to-moderate…
- Conditions
- Hypercholesterolemia, Lipid Metabolism Disorders, Lipid Metabolism, Nutraceutical
- Trial name
- CORDICOL (NCT07852481)
- Testing
- CORDICOL
- Volunteers
- 140 people
- Sponsor
- noiVita Srls
Healthy Aging, Inflammaging
The Effects of Quercefit® and Ubiqsome™ in Mitigating Inflammation and Promoting Metabolic Health
The goal of this clinical trial is to learn if Quercefit® or Ubiqsome™ can improve markers of healthy aging, blood sugar control, and heart health in older adults. It will also learn about the safety of these supplements.
- Conditions
- Healthy Aging, Inflammaging, Metabolic Health, Quercetin
- Trial name
- NCT07760506
- Testing
- Quercetin (dietary supplement), Coenzyme Q10, Rice Flour
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Applied Science & Performance Institute
Chronic Kidney Diseases
Role of Coenzyme Q10 in Chronic Kidney Disease
This randomized placebo controlled double blind parallel clinical study will be conducted on 44 non-dialysis chronic kidney disease (CKD) patients (Stages 2-3b).Clinical Study Evaluating the Role of Coenzyme Q10 as Adjuvant…
- Trial name
- NCT05942027
- Testing
- Co-Enzyme Q10
- Where
- Egypt
- Volunteers
- 44 people
- Sponsor
- Tanta University
Depigmentation Treatment, Depigmentation
Effect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation
This study aims to assess the clinical effectiveness of Co-enzyme Q10 and Vitamin C, applied individually or in combination after surgical gingival depigmentation.
- Trial name
- Effect of Coe (NCT07677826)
- Testing
- surgical depigmentation, Coenzyme Q10, Vitamin C
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Gulf War Syndrome, Persian Gulf Syndrome
Coenzyme Q10 for Gulf War Illness: A Replication Study
The purpose of this study is to assess whether a high quality preparation of ubiquinone (coenzyme Q10) benefits symptoms, function, and quality of life in veterans with Gulf War illness.
- Conditions
- Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorder, Respiratory Chain
- Trial name
- NCT06515184
- Testing
- PharmaNord Bio-Quinone Active CoQ10 Gold 100mg
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- University of California, San Diego
Borderline High LDL-cholesterol
Effects of Ubiquinol and Ubiquinone on Vascular Function in Healthy Adults With Borderline High LDL-Cholesterol
This randomized, double-blind, placebo-controlled clinical trial will evaluate the effects of Ubiquinol and Ubiquinone on vascular endothelial function in generally healthy adults with borderline high LDL-cholesterol.
- Trial name
- NCT07881601
- Testing
- Ubiquinol, Ubiquinone
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- SF Research Institute, Inc.
Pregnancy, Periodontal Disease
Effectiveness of Coenzyme Q10 and Probiotics in Periodontal Therapy During Pregnancy
This randomized controlled clinical trial aims to evaluate the effectiveness of adjunctive coenzyme Q10 and probiotic supplementation (Limosilactobacillus reuteri Prodentis®) in improving periodontal health in pregnant women…
- Conditions
- Pregnancy, Periodontal Disease, Gingivitis, Dental Plaque
- Trial name
- PREG-Q10 (NCT07029360)
- Testing
- Limosilactobacillus reuteri Prodentis®, Coenzyme Q10 Toothpaste
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Pavia
Prostate Cancer, Uterine Cancer
COQ10 and Vitamin E for Off-Target Radiation Toxicity
The goal of this supportive care study is to learn if high-dose Vitamin E and CoQ10 in combination can reduce the negative sub-acute and chronic side effects of radiation to the pelvis in adults treated for prostate, uterine…
- Conditions
- Prostate Cancer, Uterine Cancer, Cervical Cancer, Anal Cancer
- Trial name
- NCT07668284
- Testing
- Coenzyme Q10 Cap/Tab, Vitamin E Cap/Tab
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Nebraska
Cardiovascular Disease
Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)
Cardiovascular diseases are the leading causes of death and prescription drug use. Research on certain dietary supplements looks promising as a way to help reduce risk factors.
- Trial name
- PANDA (NCT04444349)
- Testing
- Coenzyme Q10, Standard Medical Therapy
- Where
- 4 sites in China
- Volunteers
- 500 people
- Sponsor
- Nanjing Medical University
Mitochondrial Disorders, Mitochondrial Genetic Disorders
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
- Conditions
- Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes
- Trial name
- NAMDC (NCT01694940)
- Where
- 17 sites in United States, Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Columbia University
Nephrotoxicity
Renoprotective Role of Vitamin C and Coenzyme Q10 in Nephrotoxicity
Cisplatin is a widely used chemotherapy drug for many solid tumors (e.g., lung, bladder, ovarian, head and neck cancers). Despite its efficacy, its clinical use is limited by severe side effects, mainly nephrotoxicity, which…
- Trial name
- VitC-CoQ10 (NCT07476443)
- Testing
- Vitamin C, Coenzyme Q 10
- Where
- Egypt
- Volunteers
- 75 people
- Sponsor
- Ain Shams University
Ovarian Response
The Effects of Coenzyme Q10 Pretreatment on Ovarian Function and Assisted Reproductive Outcomes in Patients With Ovarian Hyporesponsiveness.
This prospective, randomized, double-blind, controlled study will be conducted at Tangdu Hospital, Air Force Medical University. It plans to enroll 128 patients with poor ovarian response for a 2-year study.
- Trial name
- NCT07260773
- Testing
- Coenzyme Q10
- Volunteers
- 128 people
- Sponsor
- Tang-Du Hospital
Colorectal Cancer
The Role of Coenzyme Q10 in the Prophylaxis of Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Cancer
This study aims to evaluate the possible beneficial role of coenzyme Q10 against oxaliplatin-induced peripheral neuropathy in patients with colorectal cancer.
- Trial name
- NCT06856447
- Testing
- Coenzyme Q10, Oxaliplatin, 5-Fluorouracil (5-FU)
- Where
- Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- toqa saad mohammed mohammed
Community Acquired Pneumonia
Coenzyme Q10 in Pediatric Community-Acquired Pneumonia
The aim of this work is to assess the benefit of coenzyme Q10 supplementation, in addition to standard antibiotic and other supportive therapy, in the management of hospitalized children with community acquired pneumonia
- Trial name
- NCT07317440
- Testing
- oral coenzymeQ10
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Tanta University
ADHD
Role of Coenzyme Q in ADHD in Children
Role of Coenzyme Q in ADHD in Children
- Trial name
- NCT04216186
- Testing
- Atomoxetine, Coenzyme Q
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Sherief Abd-Elsalam