Clinical trials: Coenzyme Q10
Non-Alcoholic Fatty Liver Disease
The Effect of Coenzyme Q10 on Endothelial, Vascular and Myocardial Function
Non-alcoholic fatty liver disease (NAFLD) is associated with increased cardiovascular risk. The aim of this study is to investigate the effects of coenzyme Q10 (CoQ10) on endothelial, vascular and myocardial function in patients…
- Trial name
- NCT05941910
- Testing
- Q10
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- Attikon Hospital
Huntington's Disease
Study in PRE-manifest Huntington's Disease of Coenzyme Q10 (UbiquinonE) Leading to Preventive Trials (PREQUEL)
To establish the tolerability of treatment with 600, 1200 or 2400 mg per day of coenzyme Q10 in pre-manifest participants carrying the CAGn expansion for Huntington's Disease (HD).
- Trial name
- PREQUEL (NCT00920699)
- Testing
- CoQ10
- Where
- 13 sites in United States
- Volunteers
- 90 people
- Sponsor
- Johns Hopkins University
Congestive Heart Failure
Atorvastatin/CoenzymeQ10 in Congestive Heart Failure
The aim of this study is to compare the effect of addition of combination of Atorvastatin/CoenzymeQ10 to standard congestive heart failure (CHF) treatment versus addition of Atorvastatin alone on CHF outcomes.
- Trial name
- NCT01925937
- Testing
- Atorvastatin, Coenzyme Q10
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Isfahan University of Medical Sciences
Infertility Unexplained, Oligospermia
Evaluation of Treatment With Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile Men With Idiopathic Oligoasthenoteratospermia
Evaluation of treatment with Coenzyme Q10 and L-Carnitine on Semen Parameters in Infertile men with Idiopathic Oligoasthenoteratospermia
- Trial name
- infertility (NCT06342856)
- Testing
- co enzyme Q10 , L- Carnitine
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Aneuploidy, Pregnancy
The Effect of Co Enzyme Q10 Together With Fertility Drugs on Pregnancy Outcome of in Vitro Fertilization
The goal of our research is to increase live birth rates in infertile women and to reduce the incidence of aneuploidy leading to miscarriage and trisomies.
- Conditions
- Aneuploidy, Pregnancy, Miscarriage
- Trial name
- CoQ10-IVF (NCT01048385)
- Testing
- Coenzyme Q10 concomitant treatment
- Where
- Canada
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Systemic Lupus Erythematosus
The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus
The goal of this clinical trial is to evaluate the safety and efficacy of coenzyme Q10 supplementation in pediatric patients with SLE.
- Trial name
- NCT07096557
- Testing
- Coenzyme Q10
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Ain Shams University
Poor Ovarian Response
How Dose Coenzyme Q10 Supplementation During Infertility Treatment Effects Pregnancy Outcome
As women age the ovarian response and pregnancy rate are reduced while the rate of chromosomal abnormalities in the embryos is increased.
- Trial name
- CoQ10 (NCT00878124)
- Testing
- Coenzyme Q10 co treatment
- Where
- 2 sites in Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Breast Cancer, Chemotherapeutic Toxicity
Coenzyme Q10 and Chemotherapeutic Toxicity in Breast Cancer Patients
investigating the potential effect of Coenzyme Q10 in ameliorating and preventing the development of paclitaxel chemotherapeutic toxicity in breast cancer patients
- Trial name
- NCT06570811
- Testing
- Coenzyme Q10 200mg twice daily
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Damanhour University
Dry Eye Syndrome
Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Dry Eye
Background: Dry eye disease (DED) is a common condition causing burden on visual function and reducing quality of life. Corticosteroids and/or cyclosporine eye drops are able to improve DED symptoms, however, side effects of…
- Trial name
- DEDCO (NCT03074344)
- Testing
- XLHA+CoQ10, Hyaluronic acid (HA)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Infertility, Male, COVID-19
Effect of COVID-19 on Platelet Mitochondrial Bioenergetic, Antioxidants and Oxidative Stress in Infertile Men.
To verify the hypothesis that infertility and the effect of SARS-CoV-2 on infertility may damage platelet mitochondrial bioenergetics and endogenous coenzyme Q10 levels in infertile men.
- Trial name
- COVInfertility (NCT05421234)
- Testing
- diagnostic test and sperm analysis
- Where
- Slovakia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Comenius University
Infertility
Comparison of Acetyl- L- Carnitine& Folic Acid Versus Coenzyme Q10& Folic Acid on Semen& Hormonal Parameters& Semen Oxidative Status in Patients of Primary Infertility. A Double Blind Randomized Clinical Trial
The investigators aim is to conduct a double blind randomized clinical trial, to study the effects of Acetyl-L-Carnitine and folic acid versus Coenzyme Q10 and folic acid on Semen and hormonal parameters and semen oxidative…
- Trial name
- NCT05616000
- Testing
- Acetyl-l-carnitine, folic acid
- Where
- Pakistan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Khyber Medical University Peshawar
Progressive Supranuclear Palsy, Neurological Disorders
Effects of Coenzyme Q10 in PSP and CBD
To compare the efficacy, safety and tolerability of Coenzyme Q 10 versus placebo in patients with atypical parkinsonian syndromes corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) ).
- Trial name
- NCT00532571
- Testing
- CoQ10
- Where
- United States
- Sponsor
- Lahey Clinic
Gulf War Illness
Q10 for Gulf War Veterans
Goal: The investigators propose to test whether giving the supplement coenzyme Q10 (Q10) improves symptoms and subjective health in Gulf War veterans (GWV) with chronic, multi-symptom health problems.
- Trial name
- GULF (NCT01011348)
- Testing
- Coenzyme Q10
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of California, San Diego
Health Knowledge, Attitudes, Practice
Effect of Endurance Training-Induced Coenzyme Q10 (CoQ10) Supplementation on Myokine, Exerkine Secretion and Cognitive Functions in Long-Distance Runners
The goal of this clinical trial is to learn if CoQ10 amplifies endurance training-induced myokine and exerkine secretion and if those changes influences cognition in long-distance runners.
- Trial name
- NCT06619249
- Testing
- CoQ10 supplementation
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Gdansk University of Physical Education and Sport
Male Reproductive Problem, Infertility, Male
Impact of Co Enzyme Q10 as Adjuvant Therapy to Letrozole on Spermiogram
Worldwide infertility affects about 15 % of reproductive-age couples. In many cases, infertility can't be treated, new treatment options with promising value were involved in the recent clinical trials.
- Trial name
- NCT05847257
- Testing
- Letrozole tablets, Coenzyme Q10 table
- Where
- Iraq
- Volunteers
- 74 people
- Sponsor
- Al-Mustansiriyah University
Gulf War Syndrome, Persian Gulf Syndrome
Mitochondrial Cocktail for Gulf War Illness
The purpose of this study is to develop preliminary evidence, such as effect size and variance estimates, to guide successful conduct of a properly-powered clinical trial to assess the benefit of a mitochondrial cocktail…
- Conditions
- Gulf War Syndrome, Persian Gulf Syndrome, Mitochondrial Disorders
- Trial name
- NCT02804828
- Testing
- Individualized mitochondrial cocktail
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of California, San Diego
Parkinson's Disease
Parkinson's Disease Treatment With Coenzyme Q10
The purpose of this study is to compare the effects of varying dosage of coenzyme Q10 (CoQ10) versus a placebo in the treatment of Parkinson's disease (PD) in patients with early, untreated PD.
- Trial name
- NCT00004731
- Testing
- Coenzyme Q10
- Where
- United States
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Polycystic Ovarian Syndrome (PCOS)
Effect of Coenzyme Q10 Administration on Polycystic Ovary Syndrome
The goal of this clinical trial is to determine the effects of coenzyme Q10 supplementation on oxidative stress, inflammation and hyperandrogenism in women with polycystic ovary syndrome.
- Trial name
- PCOS (NCT06659406)
- Testing
- Coenzyme Q10
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Faisalabad
Idiopathic Infertility
Neotililty Trial: Effect of Coenzyme Q10 on Semen Parameters in Men With Idiopathic Infertility
To study the effect of coenzyme Q10 on semen parameters in men with idiopathic infertility
- Trial name
- Neotility (NCT03104998)
- Testing
- Coenzyme Q10
- Where
- Pakistan
- Sponsor
- PharmEvo Pvt Ltd
Frailty, Aging
MItochondrial Intervention for Resilience in Older Adults With Coenzyme Q10
This randomized, double-blind, placebo-controlled clinical trial will investigate whether 10 weeks of CoQ10 supplementation can improve biological resilience and functional health in community-dwelling adults aged 65 years or…
- Conditions
- Frailty, Aging, Mitochondria Health, Skin Aging
- Trial name
- MIRO-Q (NCT07772336)
- Testing
- Q10Vital® (CoQ10, ubiquinone)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana