Clinical trials: Chronic Recurrent Multifocal Osteomyelitis
Chronic Recurrent Multifocal Osteomyelitis
Chronic Recurrent Multifocal Osteomyelitis - a Bacterial Cause?
Chronic recurrent multifocal osteomyelitis (CRMO) is an immune-mediated chronic inflammatory self- limiting disease with non-suppurative inflammation involving one or multiple bone foci.
- Trial name
- NCT03433287
- Testing
- 18F-NaF-PET/MRI
- Where
- Denmark
- Volunteers
- 15 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Chronic Recurrent Multifocal Osteomyelitis
Medication Adherence Intervention in Chronic Recurrent Multifocal Osteomyelitis (CRMO)
This project aims to quantify and evaluate rates of non-adherence and barriers to medication adherence in pediatric patients with CRMO followed at Seattle Children's Hospital's robust CRMO program, which is the only clinical…
- Trial name
- NCT06232603
- Testing
- Education of medication management
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- Seattle Children's Hospital
Immune System Disease, Musculoskeletal Disease
Chronic Non-bacterial Osteomyelitis Treated With Pamidronate
In a randomized double blind placebo controlled trial to investigate the effect of pamidronate in treatment of chronic non bacterial osteomyelitis. Main objective: 1.
- Trial name
- CNOPAM (NCT02594878)
- Testing
- Pamidronatdinatrium, Natrium chloride 9mg/ml
- Where
- Denmark
- Volunteers
- 32 people
- Sponsor
- University of Aarhus
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Ocular Inflammation
Triamcinolone Versus Topical Treatment in Post Operative Phacoemulsification
Cataract extraction is one of the most common operative procedures performed throughout the world. Conventionally, patients are discharged with postoperative drops of steroids and antibiotics or a combination of both.
- Trial name
- NCT00789971
- Testing
- triamcinolone acetonide, Maxitriol
- Where
- Ireland
- Volunteers
- 150 people
- Sponsor
- Sligo General Hospital
Osteomyelitis Chronic
EFFICACY AND SAFETY OF ZOLEDRONATE VERSUS PLACEBO ON PAIN AT WEEK 12 IN PEDIATRIC PATIENTS WITH CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITIS
Chronic recurrent multifocal osteomyelitis (CRMO) is a rare auto-inflammatory bone disease that primarily affects children and/or adolescents at a median age of 10 years.
- Trial name
- POMREP (NCT07668583)
- Testing
- Zoledronic Acid / Zoledronate 4 MG/100 ML Intravenous Solution, NaCL 0.9% Intravenous Solution
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Chronic Recurrent Multifocal Osteomyelitis
Post-transition Clinical and Socio-professional Future in Adult Patients With Recurrent Multifocal Chronic Osteitis
Chronic Recurrent Multifocal Osteomyelitis (CRMO) is a rare autoinflammatory bone disease in children. Studies evaluating the quality of life of patients with CRMO are small and heterogeneous.
- Trial name
- ESPERANTO (NCT05103137)
- Testing
- Questionnaire
- Where
- 3 sites in France
- Volunteers
- 16 people
- Sponsor
- Hospices Civils de Lyon
Chronic Recurrent Multifocal Osteomyelitis, Pediatrics
Reliability and Validation of the WB-MRI Radiological Score in CRMO
This study evaluates the inter-observer reliability of a standardized WB-MRI scoring system for CRMO and its consistency with the PedCNO clinical score.
- Trial name
- NCT07483853
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Chronic Nonbacterial Osteomyelitis, Chronic Recurrent Multifocal Osteomyelitis
CHronic Nonbacterial Osteomyelitis International Registry
The objective of the study is to establish a prospective disease registry for chronic recurrent multifocal osteomyelitis (CRMO)/chronic nonbacterial osteomyelitis (CNO) in order to investigate the natural history of the disease…
- Trial name
- CHOIR (NCT04725422)
- Testing
- Methotrexate, Sulfasalazine, Leflunomide
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Seattle Children's Hospital