Clinical trials: Chronic Pain (Back / Neck), active
Chronic Non-Specific Low Back Pain, Chronic Non-specific Neck Pain
Predictive Variables of Outcome in Subjects With Chronic Rachialgia Referred to Different Pathways of Physiotherapy.
The aim of this study is to investigate the predictive value of various biopsychosocial variables on the outcomes of subjects with chronic spinal pain undergoing public health rehabilitation pathways.
- Trial name
- PRE-CBP (NCT06915896)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Spine, Low Back Pain
Differences in Mechanistic Measures (Oxytocin and Cortisol) of Therapeutic Alliance Between A Talk-Based Therapy and Soft-Tissue Mobilization in Individuals With Chronic Spinal Pain
The goal of this randomized cross-over mechanistic trial is to compare pre- and post-level cortisol and oxytocin changes in patients with chronic spine pain who receive either a hand's on (massage) or a hand's off (talk-based)…
- Conditions
- Spine, Low Back Pain, Neck Pain
- Trial name
- COTHA (NCT06987786)
- Testing
- Massage, Talk-based therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Duke University
Lumbosacral Radiculopathy, Sciatica
A Multicomponent Intervention for Patients With Lumbosacral Radiculopathy: Move-MORE
The Move-MORE study is designed to evaluate a multicomponent mindfulness and movement program for patients with lumbosacral radiculopathy.
- Conditions
- Lumbosacral Radiculopathy, Sciatica, Chronic Low Back Pain With a Neuropathic Component, Radiculopathy Lumbar
- Trial name
- Move-MORE (NCT07125027)
- Testing
- Move-MORE
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- National University of Natural Medicine
Back Pain, Neck Pain
Workplace Exercise Therapy With or Without Manual Therapy in Chronic Spinal Pain
Implementing workplace strategies to manage symptoms in office workers with chronic nonspecific spinal pain (CNSP) may improve both health- and work-related outcomes, as adherence to these interventions is more feasible in this…
- Conditions
- Back Pain, Neck Pain, Low Back Pain
- Trial name
- NCT07251959
- Testing
- Exercise therapy, Manual Therapy
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Catholic University of Murcia
Facet Joint Pain
ITX24-01 in Adult Male and Female Patients With Select Types of Severe Chronic Neck- and Lower Back Pain
The study is a single ascending dose (SAD), single-center, randomised, double-blind, placebo-controlled Phase 1b clinical trial designed to evaluate the safety, tolerability, and preliminary analgesic efficacy of ITX24-01 in…
- Trial name
- NCT07520240
- Testing
- ITX24-01, Normal Saline (0.9% NaCl)
- Where
- Australia
- Volunteers
- 32 people
- Sponsor
- Interventional AnalgesiX Inc.
Knee Osteoarthritis; Insomnia; Cervical Spondylosis; Chronic Low Back Pain; Allergic Rhinitis
Validating Blinding Maintenance of a Sham-Sensitization Control Design for Sensitization Acupuncture Trials
This study is the clinical validation component of a broader research program developing a randomized controlled trial (RCT) comparing sensitization acupuncture (an individualized technique in which treatment points are selected…
- Trial name
- NCT07868224
- Testing
- Sensitization Acupuncture, Traditional Acupuncture
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Jiangxi University of Traditional Chinese Medicine
Myofascial Pain Syndrome - Lower Back, Myofascial Pain Syndrome - Neck
Low-Energy Ultrasound, Electrical and Magnetic Field Stimulation in Therapy-Resistant Myofascial Pain Syndrome
Sonodyn is an investigational device that within this clinical investigation is intended for use in patients suffering from low back pain, tension headache or neck pain, originating from therapy-resistant myofascial pain…
- Conditions
- Myofascial Pain Syndrome - Lower Back, Myofascial Pain Syndrome - Neck, Myofascial Pain Syndrome - Tension Headache
- Trial name
- NCT05851326
- Testing
- Active Sonodyn
- Where
- 6 sites in Austria, Switzerland
- Volunteers
- 126 people
- Sponsor
- Sobet AG
Chronic Pain (Back / Neck)
Effectiveness of a Pain Neuroscience Education and Therapeutic Exercise Program Delivered by Primary Care Physiotherapists to Patients With Chronic Nociplastic Spinal Pain
The main objective of the project is to evaluate the effectiveness, in terms of quality of life, of a therapy based on an Active Coping Protocol for Non-Cancer Chronic Pain in the Primary Care setting.
- Trial name
- AP-AADC (NCT07133607)
- Testing
- education about pain and physical excersice, education about pain and physical excersice with somatosensorial treatment, Classic physiotherapy treatment with physical exercise, analgesic electrotherapy and thermotherapy
- Volunteers
- 135 people
- Sponsor
- Distrito de Atención Primaria Sevilla
Chronic Pain, Back Pain
Partners4Pain & Wellbeing: A Randomized Trial of Community Supported Complementary and Integrative Health Self-management for Back Pain
The goal of this clinical trial is to learn how well two community-based self-management programs work in people with chronic back or neck pain.
- Conditions
- Chronic Pain, Back Pain, Neck Pain, Self-management
- Trial name
- P4P (NCT06696352)
- Testing
- Partners4Pain, Keys to Wellbeing
- Where
- United States
- Volunteers
- 376 people
- Sponsor
- University of Minnesota
Cervical Pain, Posterior, Swallowing Difficulties
Tongue Pressure in Middle-Aged and Elderly Individuals With Chronic Cervical Pain
The goal of the cross-sectional study is to explore the impact of neck pain on tongue pressure in the middle-aged and elderly population and analyze the effects of different cranio-cervical positioning on tongue pressure…
- Conditions
- Cervical Pain, Posterior, Swallowing Difficulties, Swallowing Disorders
- Trial name
- NCT07021586
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons
Evaluation of an Online Peri-operative Health Education Platform for Patients Undergoing Spine Surgery: Ready Set Recover
Chronic back pain is the world's leading cause of disability, with spine surgery being a common yet costly intervention. However, many patients experience suboptimal recovery, with persistent pain and functional limitations…
- Conditions
- Medium-/Long-segment Spinal Fusion Patients, Spine Surgeons, Chronic Low Back Pain, Scoliosis Patients
- Trial name
- NCT07766824
- Testing
- Ready Set Recover
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National University of Natural Medicine
Chronic Pain, Back Pain
CARES (Comprehensive Analgesic, Recovery, and Education Support) for Surgery Trial
The goal of this clinical trial is to learn whether a combined behavioral and pharmacologic intervention can help reduce opioid use, improve pain recovery, and prevent opioid misuse after surgery in adults undergoing elective…
- Conditions
- Chronic Pain, Back Pain, Neck Pain, Opioid Misuse
- Trial name
- CARES (NCT06027099)
- Testing
- Tizanidine, MI-Opioid Taper, Enhanced Usual Care
- Where
- 4 sites in United States
- Volunteers
- 375 people
- Sponsor
- Stanford University
Back Pain, Neck Pain
Safety and Efficacy of Oral Cannabis in Chronic Spine Pain
The overall objectives of this study are to investigate the efficacy of extended cannabis treatment to reduce patient exposure to prescription opioids through its use 1) as a non-opioid analgesic treatment, and 2) as a therapy…
- Trial name
- NCT05052541
- Testing
- THC/CBD, THC
- Where
- United States
- Volunteers
- 157 people
- Sponsor
- University of Colorado, Denver
Mechanical Neck Pain
Comparative Efficacy of Magnesium Sulfate Iontophoresis and Extracorporeal Shockwave Therapy on Chronic Mechanical Neck Pain
The purpose of the study is to investigate the Comparative Efficacy of Magnesium Sulfate Iontophoresis and Extracorporeal shockwave therapy on Chronic Mechanical Neck Pain
- Trial name
- NCT07027631
- Testing
- Magnesium Sulfate Iontophoresis, Shock Wave Therapy, stretching and strengthening
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Chronic Pain, PERIPHERAL NEUROPATHY
Prospective Case Series Evaluating 6-Month and 12-Month Outcomes After Cryoneurolysis for Chronic Pain
To prospectively describe patient-centered and health utilization outcomes through 12 months after cryoneurolysis performed as routine clinical care for chronic pain at Yale.
- Conditions
- Chronic Pain, PERIPHERAL NEUROPATHY, Occipital Neuralgia, Chronic Hip Pain
- Trial name
- NCT07639060
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Yale University
Chronic Pain, Neck Pain
Moderators and Mediators (M & M Trial) of Psychosocial Treatments of Chronic Pain
Chronic musculoskeletal pain (CP) is a major public health concern. Psychosocial treatments have been shown to be efficacious when compared to largely inert control conditions, but they are characterized by modest effects on…
- Conditions
- Chronic Pain, Neck Pain, Back Pain
- Trial name
- NCT06044649
- Testing
- Cognitive Behavioral Therapy, Acceptance and Commitment Therapy, Emotional Awareness and Expression Therapy
- Where
- 2 sites in United States
- Volunteers
- 408 people
- Sponsor
- Rush University Medical Center
Neck Pain Musculoskeletal, Back Pain
Diaphragmatic Breathing Exercises and Chronic Non-spesifik Neck and Back Pain
Effects of Diaphragmatic Breathing Exercises Added to Posture and Core Stabilization Training on Pain, Body Awareness and Cardiovascular Parameters in Women with Chronic Non-spesific Neck and Back Pain
- Trial name
- NCT07683273
- Testing
- Diapragmatic Breathing, Control Group (A):
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Hacettepe University
Chronic Pain, Chronic Pain Due to Injury
Virtual Pain Education for Spinal Cord Stimulation Patients
Chronic pain is a leading cause of disability in the United States. When standard treatments fail, many patients develop treatment resistant pain and undergo Spinal Cord Stimulation (SCS) therapy.
- Conditions
- Chronic Pain, Chronic Pain Due to Injury, Failed Back Syndrome, Persistent Spinal Pain Syndrome
- Trial name
- SCS-PNE (NCT07743905)
- Testing
- SCS-PNE intervention
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Chronic Musculoskeletal Pain, Anxiety
Screening and Referral Practices for Anxiety and Depression Among Patients With Chronic Neck, Shoulder and Low Back Pain Within Physiotherapy Practices
The goal of this cross-sectional, qualitative study is to investigate whether physiotherapists screen for symptoms of anxiety and depression in patients with chronic musculoskeletal pain and to explore the facilitators and…
- Conditions
- Chronic Musculoskeletal Pain, Anxiety, Depression
- Trial name
- NCT07177547
- Testing
- Mental health screening and referral practices in physiotherapy
- Where
- Belgium
- Volunteers
- 18 people
- Sponsor
- Ana Catarina Navarro Ramalho
Low Back Pain, Chronic Pain (Back / Neck)
Digitally Delivered Treatments to Reduce Chronic Low Back Pain
This study aims to evaluate the effectiveness of pain education and clinical hypnosis delivered via a mobile app compared to a guideline-informed factsheet for reducing pain and disability in people experiencing chronic low back…
- Conditions
- Low Back Pain, Chronic Pain (Back / Neck), General Practice (GP), Primary Care Settings, Digital Health
- Trial name
- NOTUS (NCT06984354)
- Testing
- Pain education and clinical hypnosis delivered via a mobile app, Guideline-informed factsheet
- Where
- Australia
- Volunteers
- 720 people
- Sponsor
- Neuroscience Research Australia