Clinical trials: Chronic Musculoskeletal Disease
Lateral Epicondylitis
Comparison of Muscle Energy Technique and Oscillating Energy Manual Therapy in Chronic Lateral Epicondylitis
Lateral epicondylitis (LE) is a painful musculoskeletal condition caused by overuse. The condition is also called tennis elbow because it affects 50% of tennis players, notably beginners learning the one-handed backhand.
- Trial name
- NCT05354167
- Testing
- muscle energy technique, oscillating manual energy therapy
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Inflammatory Bowel Diseases, Chronic Pain
Somatosensory Profiles in Individuals With Persistent Musculoskeletal Pain and Inflammatory Bowel Disease
This study evaluates nervous system hypersensitivity in individuals with inflammatory bowel disease (IBD) and experiences of ongoing musculoskeletal (MSK) pain.
- Conditions
- Inflammatory Bowel Diseases, Chronic Pain, Central Sensitization
- Trial name
- NCT03799471
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
Pain, Knee Osteoarthritis
A Study to Evaluate the Efficacy and Safety of CG5503 Prolonged Release (PR) in Subjects With Moderate to Severe Chronic Pain Due to Osteoarthritis of the Knee
The purpose of this study is to evaluate whether tapentadol (CG5503) prolonged-release (PR) tablets at doses of 100-250 mg twice daily provide a better pain relief in patients with moderate to severe chronic pain due to…
- Trial name
- NCT00486811
- Testing
- Tapentadol ER (100 to 250 mg twice daily), Oxycodone CR (20 to 50 mg twice daily)
- Where
- 100 sites in Austria, Croatia and 11 more
- Volunteers
- 990 people
- Sponsor
- Grünenthal GmbH
Tendinopathy
Minimal Invasive Treatment of Achilles Tendinopathy: Focus on Percutaneous Release (Maffulli)
To evaluate the outcome of percutaneous paratenon release for chronic midportion Achilles tendinopathy.
- Trial name
- NCT04793971
- Testing
- percutaneous paratenon release
- Where
- Belgium
- Volunteers
- 8 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome
The Effectiveness of Temporomandibular Joint Mobilization and Exercise in Individuals With Chronic Neck Pain
To examine the effects of temporomandibular joint mobilization and exercises added to the conventional physiotherapy program on posture, functionality and muscular endurance in individuals with chronic neck pain.
- Conditions
- Temporomandibular Joint Disorders, Temporomandibular Joint Dysfunction Syndrome, Neck Pain, Chronic Pain
- Trial name
- NCT06005922
- Testing
- physiotherapy, TMJ exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Uskudar University
Cerebral Palsy, Spasticity
Spinal Cord Stimulation for Children With Cerebral Palsy
The goal of this clinical trial is to help understand spinal cord excitability in children with cerebral palsy compared to neurologically typical children.
- Trial name
- NCT07516067
- Testing
- Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Martin Piazza
Myofascial Pain Syndromes
Transcranial Magnetic Stimulation and/or Neurofunctional Electrical Acupuncture in Myofascial Chronic Pain Patients
To evaluate the hypothesis: the effects of repetitive transcranial magnetic (rTMS) stimulation and/or peripheral stimulation (neurofunctional electrical acupuncture) treatments are more effective in pain relief than placebo-sham…
- Trial name
- NCT02381171
- Testing
- Active rTMS, Active Neuroacupuncture
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Chronic Fatigue Syndrome
Therapy for Chronic Fatigue Syndrome: A Presumptive Mitochondrial Disorder
The purpose of this study is to determine whether therapy that has been shown to be beneficial for mitochondrial diseases is also beneficial for Chronic Fatigue Syndrome (CFS) patients.
- Trial name
- NCT01872351
- Testing
- Nutraceuticals
- Where
- United States
- Sponsor
- Columbia University
Rheumatoid Arthritis
Rheumatoid Arthritis: Comparison of Active Therapies in Patients With Active Disease Despite Methotrexate Therapy
Rheumatoid arthritis (RA) is a chronic inflammatory disease of the joints leading to joint destruction, with significant long-term morbidity and mortality.
- Trial name
- RACAT (NCT00405275)
- Testing
- Etanercept, methotrexate, Sulfasalazine
- Where
- 37 sites in United States, Canada
- Volunteers
- 353 people
- Sponsor
- US Department of Veterans Affairs
Cerebral Palsy
Effect of Dysport Injections on Energy Expenditure and Walking Efficiency in Children With Cerebral Palsy
This study aims to evaluate the efficacy of single event multi level chemoneurolysis with the abobotulinumtoxin A drug, Dysport®, on walking energy expenditure and gait in children with spastic diplegia cerebral palsy.
- Trial name
- NCT03469999
- Testing
- Dysport Injectable Product
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Columbia University
Low Back Pain, Adult
Reliability of Function Tests for People With Back Pain.
Back pain is often accompanied by changes in function. The performance of individuals with their backs on their wills may become more functional.
- Trial name
- NCT03645616
- Testing
- 6-minute walk test, 10 meters walk test, 30 Second Sit to Stand Test
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Alessandro Haupenthal
Cerebral Palsy
Physical Therapy After Anti-spastic Treatment in Children With Cerebral Palsy
It is the primary purpose of this pilot study to investigate if physical therapy with strength training is better at improving muscle and gait function after anti-spastic treatment with Botulinum toxin compared to physical…
- Trial name
- NCT00552721
- Testing
- Physical therapy with strength training, Physical therapy without strength training
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Hvidovre University Hospital
Metatarsalgia
Physiotherapy for Chronic Metatarsalgia
The pilot study was conducted in the form of an open prospective single-arm observational study with 28 patients who received physiotherapy at the Spiraldynamik® Med Center in Zurich.
- Trial name
- NCT02578615
- Testing
- physiotherapy
- Volunteers
- 28 people
- Sponsor
- Spiraldynamik AG
Tendinopathy, Jumper's Knee
A Study of the Effect of Time-of-day of Training on Chronic Patellar Tendinopathy
The study is a 12-week human study where 60 participants with chronic patellar tendinopathy (more than 3 months symptoms duration) are randomised to undergo 12 weeks of targeted resistance exercise either in the morning or in the…
- Trial name
- TENDOTIME (NCT06217432)
- Testing
- Resistance training for knee extensors
- Where
- Denmark
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Bispebjerg Hospital
Joint Pain, Chronic Pain
Predicting Chronic Opioid Use Following Lower Extremity Joint Arthroplasty
Personalized medicine is a concept in which medical care is individualized to a patient based on their unique characteristics, including comorbidities, demographics, genetics, and microbiome.
- Conditions
- Joint Pain, Chronic Pain, Opioid Use
- Trial name
- NCT04974463
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of California, San Diego
Renal Osteodystrophy
Low Magnitude Mechanical Stimuli Effects on Bone Structure in ESRD
The proposed 6 month pilot and feasibility randomized trial will evaluate LMMS as an anabolic stimulus to bone in 30 adults on maintenance hemodialysis.
- Trial name
- NCT00364234
- Testing
- Low magnitude mechanical stimuli
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Osteoarthritis of the Knee, Insomnia
Sleep, Pain and Inflammatory Processes in Older Adults With Osteoarthritis
The purpose if the study is to determine whether improving sleep, especially slow wave or "deep" sleep, in older adults with osteoarthritis (OA) and insomnia reduces pain sensitivity and inflammatory responses to pain, and…
- Conditions
- Osteoarthritis of the Knee, Insomnia, Knee Pain
- Trial name
- NCT01683799
- Testing
- Cognitive Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Rochester
Cerebral Palsy, Spastic Hemiplegic Cerebral Palsy
Mechanical Vibration on Children With Cerebral Palsy
The purpose of this study was to assess the effect of mechanical vibration on spasticity and balance in children with cerebral palsy.
- Trial name
- NCT05593406
- Testing
- Vibration Group, Control Group
- Where
- Greece
- Volunteers
- 13 people
- Sponsor
- University of Thessaly
Running-related Injuries, Medial Tibial Stress Syndrome
Machine Learning-Based Risk Identification and Precision Exercise for Common Running Injuries
This study aims to identify biomechanical risk factors associated with common running-related injuries in recreational runners using machine learning analysis.
- Conditions
- Running-related Injuries, Medial Tibial Stress Syndrome, Patellofemoral Pain, PFP, Chronic Achilles Tendinopathy
- Trial name
- NCT07689916
- Testing
- Multidimensional Precision Intervention, Precision Exercise Intervention
- Where
- China
- Volunteers
- 204 people
- Sponsor
- Zeyi Zhang
Lipedema, Knee Osteoarthritis
The Effect of Lipedema on Knee Osteoarthritis
This study will be one of the few to examine the effect of lipedema on knee osteoarthritis in a comparative manner with a control group within the same osteoarthritis context.
- Conditions
- Lipedema, Knee Osteoarthritis, Knee Acute and Chronic Pain, Knee
- Trial name
- NCT07575555
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 76 people
- Sponsor
- Izmir Democracy University
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.