Clinical trials: Chronic Mental Disorder
Genito-Pelvic Pain/Penetration Disorder, Dyspareunia
VIBRating vs Traditional Therapy for Treatment of ENTry Dyspareunia
The goal of this randomized controlled trial is to determine whether the use of a novel vibrating pelvic floor therapeutic device ("Kiwi") improves sexual function in sexually active women aged 18 and older with genito-pelvic…
- Conditions
- Genito-Pelvic Pain/Penetration Disorder, Dyspareunia, Vaginismus, Pelvic Pain
- Trial name
- VIBRENT (NCT06840314)
- Testing
- Pelvic floor therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medstar Health Research Institute
Chronic Pain, Opioid Use Disorder
Virtual Reality for Chronic Pain and Opioid Use Disorder Pilot
This is a pilot feasibility study of a virtual reality device for patients with co-morbid chronic pain and opioid use disorder.
- Trial name
- NCT05546749
- Testing
- RelieVRx
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Albert Einstein College of Medicine
Disorders of Consciousness Due to Severe Brain Injury, Minimally Conscious State
Assessment of Consciousness With CRS-R and SECONDs
Accurately determining the level of consciousness in patients with severe brain injury is essential for treatment planning, prognosis, and ethical decision-making.
- Conditions
- Disorders of Consciousness Due to Severe Brain Injury, Minimally Conscious State, Unresponsive Wakefulness Syndrome
- Trial name
- AssessConsc (NCT07456020)
- Testing
- Simplified Evaluation of CONsciousness Disorders (SECONDs), Coma Recovery Scale-Revised (CRS-R)
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- BDH-Klinik Hessisch Oldendorf
Chronic Fatigue Syndrome/ Myalgic Encephalitis (CFS/ME), Post COVID Syndrome
Effectiveness and Safety of a Tele-Rehabilitation Program on Fatigue and Related Variables in Chronic Fatigue Syndrome and Post COVID Syndrome
This is a randomized, single-blind clinical trial that aims to evaluate the effectiveness of a tele-rehabilitation program based on mindful and conscious movement-based exercise (including adapted yoga, breathing exercises, and…
- Trial name
- NCT06978582
- Testing
- Mindful and conscious movement-based exercise, Conventional exercise
- Where
- Spain
- Volunteers
- 147 people
- Sponsor
- University of Seville
Chronic Disease, Mental Health
Alaska Alliance for Community Engagement Phase II: Partnership for Action Toward Health
The AK ACE-PATH Phase II study aims to pilot and implement a novel intervention, Tools for Arctic Health Promotion (TAHP), to address Alaska Native (AN) community priorities related to local health and community-level resilience.
- Conditions
- Chronic Disease, Mental Health, Caridovascular Disease, Stress
- Trial name
- AK ACE-PATH (NCT07801989)
- Testing
- Tools for Arctic Health Promotion
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- University of Alaska Fairbanks
Endometriosis
Endometriosis Pelvic Pain Interdisciplinary Cohort Data Registry
The purpose of this data registry is to prospectively collect data from patients referred to an interdisciplinary clinic for pelvic pain and endometriosis to investigate long-term patient outcomes, prognosis, predictors, causes…
- Trial name
- EPPIC (NCT02911090)
- Testing
- Data Registry
- Where
- Canada
- Volunteers
- 5,000 people
- Sponsor
- BC Women's Hospital & Health Centre
Cognition, Affect (Mental Function)
ETASCAN Project: ETAS Project 2
This study aims to investigate the chronic effects of ETAS® on cognitive, affective and neural outcomes in healthy adults aged 60-80 years with mild to moderate subjective cognitive complaints.
- Conditions
- Cognition, Affect (Mental Function), Sleep, MRI
- Trial name
- ETASCAN (NCT07550140)
- Testing
- ETAS®
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Reading
Alcohol Dependence
Contingency Management for Chronic Recidivist Alcohol-Dependent Patients
The purpose of this study is to evaluate the efficacy of prize contingency management (CM) in reducing in-patient detoxification services for chronic recidivist alcohol-dependent patients.
- Trial name
- NCT00408161
- Testing
- Contingency Management, standard case management treatment
- Where
- United States
- Volunteers
- 104 people
- Sponsor
- UConn Health
Opioid-use Disorder, Chronic Pain
Randomized Trial of ACT and a Care Management App in Primary Care-based Buprenorphine Treatment
The proposed IMPOWR Research Center at Montefiore-Einstein (IMPOWR-ME) will create a multidisciplinary and synergistic program of research to test multimodal treatments that address both chronic pain and opioid use disorder.
- Trial name
- NCT05039554
- Testing
- Acceptance and commitment therapy, Valera Smartphone Application, Treatment as Usual
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Albert Einstein College of Medicine
Mental Disorders, Severe, Mental Illness Persistent
Physical Activity to Reduce Cardiometabolic Risk in Adults With Serious Mental Illness (PARCS) Study
The aim of this project is to trial the protocol of a park-based physical activity (PA) intervention in adults with serious mental illness (SMI) in a community mental health center's peer support program.
- Trial name
- PARCS (NCT05457179)
- Testing
- Park-based physical activity, Active Control
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Kansas State University
Mind-Body Therapies, Insomnia Chronic
Ba Duan Jin for CI With Hyperarousal/Anxiety
This randomized controlled trial aims to evaluate the effectiveness of Ba Duan Jin exercise in treating chronic insomnia (CI) with comorbid hyperarousal and anxiety symptoms.
- Trial name
- NCT06969079
- Testing
- Ba Duan Jin Exercise plus Sleep Hygiene Education, Sleep Hygiene Education
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Xuanwu Hospital, Beijing
Chronic Low-back Pain, Anxiety
EaseVRx-8w+ for the Treatment of Chronic Lower Back Pain
The aim of this randomized controlled trial (RCT) is to assess outcomes for virtual reality therapy (including pain intensity, pain interference, anxiety, depression, physical function, sleep, behavioral skills development…
- Conditions
- Chronic Low-back Pain, Anxiety, Depression
- Trial name
- AVR_HEOR (NCT05263037)
- Testing
- EaseVRx
- Where
- United States
- Volunteers
- 1,093 people
- Sponsor
- AppliedVR Inc.
Child Development Disorder, Activity, Motor
Psychometric Properties of the Turkish Version of Young Children's Participation and Environment Measure
The Young Children's Participation and Environment Measure (YC-PEM) is a parent/caregiver reported outcome measure that evaluates the participation status and environmental factors of children under five years old.
- Trial name
- NCT04936269
- Where
- Turkey (Türkiye)
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dementia, Traumatic Brain Injury (TBI)
Clinical Characteristics of Dementias That Occur Remotely After Traumatic Brain Injury in Retired Military Personnel
The objective of this study is to measure the frequency and clinical types of mild cognitive impairment (MCI) or dementia that occur among up to 150 military retirees with and without a history of traumatic brain injury (TBI)…
- Conditions
- Dementia, Traumatic Brain Injury (TBI), Mild Cognitive Impairment (MCI), Chronic Traumatic Encephalopathy (CTE)
- Trial name
- NCT01891383
- Where
- 2 sites in United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Uniformed Services University of the Health Sciences
Chronic Pain, Chronic Pain Due to Injury
Virtual Pain Education for Spinal Cord Stimulation Patients
Chronic pain is a leading cause of disability in the United States. When standard treatments fail, many patients develop treatment resistant pain and undergo Spinal Cord Stimulation (SCS) therapy.
- Conditions
- Chronic Pain, Chronic Pain Due to Injury, Failed Back Syndrome, Persistent Spinal Pain Syndrome
- Trial name
- SCS-PNE (NCT07743905)
- Testing
- SCS-PNE intervention
- Volunteers
- 50 people
- Sponsor
- University of Arkansas
Fibromyalgia, Insomnia
Sleep and Pain Interventions in Women With Fibromyalgia
Insomnia affects 67-88% of chronic pain patients. SPIN II is a randomized controlled clinical trial that will compare the effects of two cognitive behavioral sleep treatments in women with fibromyalgia and insomnia.
- Conditions
- Fibromyalgia, Insomnia, Chronic Widespread Pain
- Trial name
- SPIN-II (NCT03744156)
- Testing
- Cognitive Behavioral Treatment-Insomnia, Sleep Hygiene Education
- Where
- United States
- Volunteers
- 131 people
- Sponsor
- University of Missouri-Columbia
Alzheimer's Disease
Chronic Electrical Stimulation of Hypothalamus/Fornix in Alzheimer's Disease
Alzheimer's Disease (AD) is the most common cause of dementia for which no treatment has shown consistent efficacy to stop or slow down the disease.
- Trial name
- NCT00888056
- Testing
- Bilateral chronic electrical stimulation of the hypothalamus/fornix
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Insomnia Chronic, Fecal Microbiota Transplantation
The Efficacy and Safty of FMT in Patients With CID
This clinical trial aims to learn about the efficacy of fecal microbiota transplantation in patients with chronic insomnia disorder.
- Conditions
- Insomnia Chronic, Fecal Microbiota Transplantation, Sleep Disorder, Depression
- Trial name
- NCT05917379
- Testing
- fecal microbiota, synbiotics
- Where
- 7 sites in China
- Volunteers
- 80 people
- Sponsor
- Peking University Sixth Hospital
Long COVID
Evaluating the Neuromodulatory Effect of Ketamine in Long COVID-19
Plain Language Summary: This study is a clinical trial to see if ketamine can help treat symptoms of Long COVID, especially fatigue and problems with thinking clearly (often called "brain fog").
- Trial name
- NCT06821087
- Testing
- Ketamine only
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Texas at Austin
Physical Health, Mental Illnesses
Physical Health Improvement Intervention for People Admitted to Mental Health Service
This study aims to codesign and implement a physical health improvement behaviour change intervention for people being treated for a mental illness in a mental health inpatient unit of a regional hospital.
- Conditions
- Physical Health, Mental Illnesses, Chronic Diseases
- Trial name
- NCT06996899
- Testing
- Health Improvement Profile (HIP), Clinician Health Improvement Profile user training
- Volunteers
- 25 people
- Sponsor
- Charles Darwin University
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