Clinical trials: Chronic Low Back Pain (CLBP)
Chronic Low Back Pain (CLBP), Low Back Pain
Chronic Low Back Pain and Osteopathic Manipulation Treatment
The goal of this clinical trial is to learn if adding Osteopathic Manipulative Therapy (OMT) to the usual medical care provided at the VA (usual VA care) improves treatment outcomes in individuals with chronic low back pain…
- Trial name
- NCT07161661
- Testing
- Usual VA Care, Osteopathic manipulative treatment
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Edward Hines Jr. VA Hospital
Degenerative Disc Disease, DDD
Biologic Injection For Adults With Lumbar Disc Herniation
The goal of this clinical trial is to find out whether adding a bone-marrow aspirate concentrate (BMAC) injection during surgery can improve recovery in adults undergoing lumbar microdiscectomy for a lumbar disc herniation.
- Conditions
- Degenerative Disc Disease, DDD, Degenerative Disc Disease Lumbar, Degenerative Disc Disease, Lumbar
- Trial name
- BMAC (NCT07386548)
- Testing
- Bone Marrow Aspirate Concentrate (BMAC)
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Weill Medical College of Cornell University
Chronic Low-back Pain (cLBP)
Pain Phenotypes in Individuals With Chronic Low Back Pain
This observational cross-sectional study aims to determine pain phenotypes in individuals with chronic low back pain (CLBP). Participants will be classified according to a mechanism-based clinical pain phenotyping algorithm as…
- Trial name
- NCT07766200
- Testing
- Pain classification method
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kutahya Health Sciences University
Meralgia Paresthetica, Chronic Low-back Pain (cLBP)
Dry Needling Versus Cyriax Technique on Pain, Paraesthesia and Functional Disability in Patients With Chronic Low Back Pain
This study is designed to compare the effectiveness of two physiotherapy techniques-Dry Needling and the Cyriax Technique-in people suffering from chronic low back pain (CLBP) that radiates to the outer thigh, a condition…
- Trial name
- NCT07089472
- Testing
- Dry Needling Therapy, Cyriax Technique
- Where
- Pakistan
- Volunteers
- 80 people
- Sponsor
- University of Lahore
Fibromyalgia, Lupus Erythematosus, Systemic
Brief Pain Exposure Therapy (BPET) For Nociplastic Pain
This study is intended to test whether a brief Zoom-based behavioral treatment can help adults with fibromyalgia (FM), Lupus, chronic pelvic pain, and chronic low back pain learn effective strategies for reducing pain, disability…
- Conditions
- Fibromyalgia, Lupus Erythematosus, Systemic, Chronic Pelvic Pain, Chronic Low Back Pain (CLBP)
- Trial name
- BPET (NCT06208514)
- Testing
- Brief pain exposure therapy (BPET)
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Michigan
Chronic Low Back Pain (CLBP)
Focal Extracorporeal Shock Wave Therapy With Two Different Dosing Regimens for Chronic Low Back Pain
The purpose of this clinical trial is to evaluate and compare the efficacy of two different dosing regimens of focal extracorporeal shock wave therapy (F-ESWT) in patients diagnosed with chronic mechanical low back pain.
- Trial name
- ESWT-LBP (NCT07646132)
- Testing
- Focal Extracorporeal Shock Wave Therapy (F-ESWT)
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Armando Tonatiuh Avila Garcia
Chronic Low Back Pain (CLBP), Physical Therapy
Psilocybin-Assisted Physical Therapy in Chronic Low Back Pain
The purpose of this research study is to investigate whether a single administration of psilocybin can improve interoceptive awareness (awareness of bodily sensations) in individuals with chronic low back pain undergoing physical…
- Conditions
- Chronic Low Back Pain (CLBP), Physical Therapy, Psilocybin
- Trial name
- NCT07306364
- Testing
- Psilocybin 10 mg, Psilocybin 25 mg, Niacin 100 mg
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Yale University
Chronic Low Back Pain
Transcranial Stimulation for Physiotherapy Optimisation - Chronic Low Back Pain (STOP-CLBP)
The main objective of this study is to investigate the effects of non-invasive brain stimulation (the so-called transcranial direct current stimulation ; tDCS) combined with an active physiotherapy program on the multidimensional…
- Trial name
- STOP-CLBP (NCT05757609)
- Testing
- Anodal tDCS combined with active physiotherapy
- Where
- Switzerland
- Volunteers
- 48 people
- Sponsor
- Stephane ARMAND
Chronic Low Back Pain (CLBP)
Proprioceptive, Calisthenic, and Kinesthetic Exercises for Chronic Low Back Pain
Numerous studies have emphasized the debilitating effects of chronic low back pain (CLBP), which persists for over 12 weeks and impacts approximately 20% of the global population.
- Trial name
- NCT06751719
- Testing
- core stabilization exercises, heat therapy, proprioceptive exercises
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Sleep Disturbance, Chronic Low-back Pain
Trans Cranial Direct Current Stimulation Along With Craniosacral Therapy on Sleep Disturbances in Patients With Chronic Low Back Pain
Sleep problems in patients with CLBP are a very common complication and is the most neglected part of the management. Though previous literature suggested that sleep problems need to be managed in patients with CLBP, no physical…
- Trial name
- NCT03976232
- Testing
- Trans cranial Direct Current Stimulation (tDCS), Craniosacral therapy (CST), tDCS+ CST
- Volunteers
- 60 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Chronic Low-back Pain (cLBP)
Core Muscle Training in Patients With Chronic Mechanical Low Back Pain
The goal of this study is to train core muscles in patients with chronic low back pain, the researchers will compar between the effect of suspension exercise core muscle training and pressure biofeed back core muscle training
- Trial name
- NCT07448766
- Testing
- suspension execises, pressure biofeedback training, advices
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Chronic Low Back Pain (CLBP)
Comparison Between Lumbar Stabilization Exercises and Lumbar Manipulation on Multifidus Muscle in Chronic Low Back Pain This Study Will Investigate and Compare the Effect of Lumbar Stabilization Exercises and Manipulation on Multifidus Muscle in Chronic Low Back Pain
Histological and morphological changes of multifidus muscle have been reported in lumbar disc herniation (LDH), but there is scarce research comparing the efficacy of different treatment programs that can correct multifidus…
- Trial name
- NCT06796023
- Testing
- Stretching and strengthening exercises for back muscles, Lumbar stabilization Exercises, Lumbar Manipulation
- Volunteers
- 60 people
- Sponsor
- Cairo University
Mechanical Low Back Pain
Association Between the Duration of Smart Phone Use and Back Dysfunction in Patients With Low Back Pain
This study investigates the association between the duration of smart phone use and back pain and proprioception deficits in patients with chronic mechanical low back pain (CLBP).
- Trial name
- NCT03517410
- Testing
- Smart phone use
- Where
- Egypt
- Volunteers
- 62 people
- Sponsor
- Aliaa Rehan Youssef
Cancer Survivorship, Chronic Low Back Pain (CLBP)
Exploring Physiotherapist's Knowledge, Attitudes, Beliefs and Clinical Decision-making Regarding Physical Activity in Chronic Pain Management.
Chronic pain is a globally increasing problem, with enormous impact on the individual and society. Within the treatment of chronic pain, physical activity is a key strategy to improve pain-related complaints.
- Conditions
- Cancer Survivorship, Chronic Low Back Pain (CLBP), Physiotherapy and Rehabilitation
- Trial name
- PPS (NCT06605729)
- Testing
- e-learning
- Where
- Belgium
- Volunteers
- 330 people
- Sponsor
- Universiteit Antwerpen
Chronic Low Back Pain
Management of Chronic Low Back Pain in Older Adults Using Auricular Point Acupressure
Almost one-third (30%) of persons 60 years and older suffer from cLBP and cause a significant negative impact on individuals and society in the U.S.
- Trial name
- NCT03589703
- Testing
- Target ear points related to chronic low back pain (T-APA), Non-Target ear Points not related to chronic low back pain (NT-APA), Enhanced Educational Control Group (CG-2)
- Where
- 2 sites in United States
- Volunteers
- 272 people
- Sponsor
- The University of Texas Health Science Center, Houston
Low Back Pain, Mechanical
Short Terms Effects of Medial Branch Block vs Para-spinal Muscle Injection in Patients With Non-specific CLBP
This study compares the efficacy of medial branch block (MBB) vs. paravertebral deep intramuscular (PDI) injection for pain relief in chronic low back pain.
- Trial name
- NCT02521519
- Testing
- Medial branch block in one side, paravertebral deep intramuscular (PDI) injection
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Chronic Low Back Pain (cLBP)
Integration of Virtual Reality and Traditional Acupuncture: From Education to Clinical Practice.
This research project aims to develop and validate whether a "VR-assisted traditional acupuncture therapy model" provides superior pain relief and functional improvement compared to acupuncture alone.
- Trial name
- NCT07816796
- Testing
- VR-Assisted Acupuncture Group, Traditional Acupuncture Group, Conventional Care / Outcome Assessment Only
- Volunteers
- 90 people
- Sponsor
- China Medical University Hospital
Chronic Pain, Chronic Back Pain
Virtual Reality Treatment for Adults With Chronic Back Pain (VRNT)
Participants with chronic back pain will complete an online Qualtrics eligibility survey. After signing a consent form, eligible participants enter a two-week baseline period ("Baseline Period"), during which they complete two…
- Conditions
- Chronic Pain, Chronic Back Pain, Chronic Lower Back Pain (CLBP)
- Trial name
- NCT07033195
- Testing
- Skills-based Virtual Reality Therapy, Distraction-based Virtual Reality Therapy
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- CognifiSense Inc.
Chronic Low Back Pain (CLBP)
Comparison of the Immediate Effect of Passive vs. Passive-Active Hamstring Stretching on Flexibility in Patients With Chronic Low Back Pain
The goal of this clinical trial is to determine whether a combination of passive and active hamstring stretching (PAS) is more effective than passive stretching alone (PS) in improving flexibility in patients with chronic low…
- Trial name
- EFIM2 (NCT06888895)
- Testing
- Passive-active stretching (PAS), Passive hamstring stretching
- Where
- 2 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Clermont-Ferrand
Chronic Low Back Pain (CLBP)
Study of Correlation Between Serum BDNF Levels and Pfirmann Grading and IL- 1β
Brain-derived neurotrophic factor (BDNF) is a protein belonging to the neurotrophin family, known to be involved in neuronal survival, growth, and synaptic plasticity.
- Trial name
- NCT07807839
- Testing
- blood sampling for ELISA
- Where
- South Korea
- Volunteers
- 59 people
- Sponsor
- Keimyung University Dongsan Medical Center