Clinical trials: Chronic Low Back Pain
Non-specific Chronic Low Back Pain, Healthy Volunteer
Behavioral Indicators of Pain Representation
The goal of this observational study is to compare the postural response to the mental simulation of everyday situations identified as painful in participants with non-specific low back pain and healthy volunteers.
- Trial name
- ICOR (NCT06669767)
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Universite de Picardie Jules Verne
Low Back Pain, Depression
Cipralex in Treatment of Depressive Symptoms and Chronic Back Pain
Chronic low back pain (CLBP) is one of the most frequent forms of chronic pain and can result in significant functional impairment. This is often associated with major depression too.
- Trial name
- NCT00227292
- Testing
- Escitalopram
- Where
- Germany
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Chronic Low Back Pain
Effect of High Intensity Interval Exercise on Chronic Low Back Pain Patients
Patients with low back pain (LBP) often report an overall reduced physical activity and fitness that could consequently lead to an altered autonomic balance.
- Trial name
- CLBP (NCT03753165)
- Testing
- High intensity interval exercise
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Patients With Chronic Mechanical LBP
Core Stability Exercise Versus Aerobic Exercise on Pain, Range of Motion and Function in Patients With Chronic Mechanical Low Back Pain: Randomized Controlled Trial
Chronic mechanical low back pain (CMLBP) is a prevalent musculoskeletal condition characterized by persistent pain originating from the spine, muscles, ligaments, or intervertebral discs.
- Trial name
- NCT06634511
- Testing
- core stability exercises
- Where
- Saudi Arabia
- Volunteers
- 45 people
- Sponsor
- Cairo University
Chronic Low Back Pain
Physical CAM Therapies for Chronic Low Back Pain
This is a pilot randomized trial intended to evaluate the effectiveness of acupuncture, chiropractic and massage for chronic back pain in older and younger adults.
- Trial name
- NCT00065975
- Testing
- massage therapy, chiropractic, acupuncture
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Acute Low-back Pain, Chronic Low-back Pain
Impact of DuoTherm Compared to TENS on Pain and Disability With Acute and Chronic Low Back Pain
Evaluate pain and disability change in Low Back Pain with DuoTherm Compared to Active Control
- Conditions
- Acute Low-back Pain, Chronic Low-back Pain, Pain, Intractable
- Trial name
- NCT04494698
- Testing
- Duotherm VibraCool Back Device, TENS 8-channel unit
- Where
- 2 sites in United States
- Volunteers
- 160 people
- Sponsor
- MMJ Labs LLC
Low Back Pain, Adult
Reliability of Function Tests for People With Back Pain.
Back pain is often accompanied by changes in function. The performance of individuals with their backs on their wills may become more functional.
- Trial name
- NCT03645616
- Testing
- 6-minute walk test, 10 meters walk test, 30 Second Sit to Stand Test
- Where
- Brazil
- Volunteers
- 33 people
- Sponsor
- Alessandro Haupenthal
Low Back Pain, Recurrent, Neuropathic Pain
CRF vs WCRF or PRF-DRG in CLBP of FJ Origin and RFA Failure of MBDR: Central Sensitization and Aberrant Nerve Sprouting
The investigators will select two study groups from a population of patients with severe chronic low back pain (CLBP) of facet joint (FJ) origin already treated with conventional radiofrequency ablation (CRFA) of the medial…
- Conditions
- Low Back Pain, Recurrent, Neuropathic Pain, Facet Joint Pain, Central Sensitisation
- Trial name
- NCT04542798
- Testing
- Radiofrequency COSMAN
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Hospital General Universitario de Valencia
Chronic Non-Specific Low Back Pain, Cognitive Decline
The Impacts of Chronic Non-specific Low Back Pain on Cognitive Functions of Older Adults
Chronic non-specific low back pain (CNSLBP) is a prevalent condition among older adult and has been associated with an increased risk of executive function impairment.
- Conditions
- Chronic Non-Specific Low Back Pain, Cognitive Decline, Cross-Sectional Study, Older Adults
- Trial name
- NCT06704425
- Testing
- For observational studies, participants are not assigned an intervention as part of the study.
- Where
- 3 sites in Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Low Back Pain, Chronic Pain
Cognitive Muscular Therapy for Low Back Pain
The primary aim of this study is to adapt Cognitive Muscular Therapy so that it can be used to manage chronic low back pain. A secondary aim is to understand the potential therapeutic benefit of this intervention.
- Conditions
- Low Back Pain, Chronic Pain, Muscle Tightness
- Trial name
- CMT-LBP (NCT05611476)
- Testing
- Cognitive Muscular Therapy for low back pain
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- University of Salford
Chronic Low Back Pain (CLBP)
Lumber Stabilization Exercise Versus Back Endurance Exercise Among Female University Students
Low Back Pain (LBP) as estimates show that up to 84% of adults will experience LBP at some point in their lifetime, ranking it as a leading cause of disability globally.
- Trial name
- NCT07163117
- Testing
- lumbar stabilization exercises, endurance training, Home based program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Low Back Pain, Chronic Pain
Nonpharmacologic Pain Management in FQHC Primary Care Clinics
The goal of this study is to improve pain management and reduce opioid reliance for patients with chronic back pain in Utah Federally-Qualified Health Centers (FQHCs).
- Trial name
- BeatPain Utah (NCT04923334)
- Testing
- Brief Pain Teleconsult, Telehealth Physical Therapy
- Where
- 2 sites in United States
- Volunteers
- 500 people
- Sponsor
- University of Utah
Chronic Low Back Pain, Self-Management
Physical Activity on Neurophysiologic Gene Expression Profiles of Chronic Low Back Pain
This pilot project will provide an understanding of the contextual variables responsible for chronic low back pain. These variables include, genetic variation, pain sensitivity, reactivity, pain catastrophizing, perceived stress…
- Trial name
- PROPEL (NCT03637998)
- Testing
- Problem-solving Pain to Enhance Living Well (PROPEL)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Connecticut
Low Back Pain
Study Of The Efficacy Of Neurolysis In Functional Recovery From Chronic Nonspecific Low Back Pain
This is a prospective, randomized, double-blind, placebo-controlled study. In an initial phase, 100 patients with chronic low back pain will be included in this study.
- Trial name
- NCT01190033
- Testing
- Neurotome OFF, neurolysis
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- University of Sao Paulo
Chronic Low Back Pain
Yoga for Veterans With CLBP
Chronic low back pain (CLBP) is a prevalent condition among VA patients, but many current treatment options have limited effectiveness.
- Trial name
- NCT02524158
- Testing
- Yoga Therapy for CLBP
- Where
- United States
- Volunteers
- 152 people
- Sponsor
- VA Office of Research and Development
Chronic Low Back Pain, Gait
Complexity & Distraction in LBP
Motor control, notably expressed through the complexity of the variability of the locomotor pattern, is disturbed at the central level by an apprehension of pain and movement, more than pain itself (or by biomechanical /…
- Conditions
- Chronic Low Back Pain, Gait, Motor Activity
- Trial name
- CoDiLoBP (NCT03633578)
- Testing
- walk test
- Where
- France
- Volunteers
- 16 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Brain Network Functional Connectivity
Brain Network fMRI Analysis in Proprioceptive Training for Chronic Low Back Pain
Through longitudinal analysis of dynamic changes in DMN functional connectivity before and after sensory training intervention, combined with pain behavioral and functional improvement indicators, this study systematically…
- Trial name
- NCT07308249
- Testing
- Multimodal Imaging Evaluation
- Volunteers
- 40 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Mechanical Low Back Pain, Paraspinal Muscles
Effects of Back Muscles Endurance Training in Patients With Chronic Mechanical Low Back Pain
Low back pain is one the leading cause of disability and affecting many individuals. Chronic low back pain is associated with restriction in daily physical activities that ultimately leads to disuse atrophy of muscles.
- Conditions
- Mechanical Low Back Pain, Paraspinal Muscles, Muscle Stretching Exercises
- Trial name
- NCT05052840
- Testing
- Muscle endurance training (MET), Conventional Treatment
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Chronic Low Back Pain
Case Series Evaluation of Psychodynamic Interpersonal Therapy in Chronic Low Back Pain
Many people in the world have chronic pain; this is pain which lasts more than twelve weeks. Pain can cause people to feel low in mood and change how they feel about themselves and others around them.
- Trial name
- NCT03658226
- Testing
- Psychodynamic Interpersonal Therapy (PIT)
- Where
- United Kingdom
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Charlotte Morgan
Pain, Low Back Pain
Efficacy and Safety Study of Buprenorphine HCl Buccal Film in Subjects With Low Back Pain
The purpose of this study is to determine whether buprenorphine hydrochloride (HCl) buccal film is effective and safe in the treatment of chronic low back pain (CLBP).
- Trial name
- NCT01256450
- Testing
- Buprenorphine
- Where
- 24 sites in United States
- Volunteers
- 334 people
- Sponsor
- BioDelivery Sciences International
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