Clinical trials: Chronic Headache
Short Lasting Unilateral Neuralgiform Headache Attacks
Phase 1b Study in Patients With Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA)
This exploratory open-label phase 1b, ascending dose study is to evaluate the effects of psilocybin on cognition in patients with Chronic Short-Lasting Unilateral Neuralgiform Headache Attacks (SUNHA)
- Trial name
- NCT04905121
- Testing
- Psilocybin
- Where
- United Kingdom
- Volunteers
- 4 people
- Sponsor
- Beckley Psytech Limited
Chronic Pain, Pelvic Pain
Vibratory Stimulation for the Treatment of Chronic Pain
The purpose of this study is to perform a first in man study with VCR stimulation of the belly and back for patients with chronic pain conditions including pelvic pain, functional abdominal pain, or low back pain.
- Conditions
- Chronic Pain, Pelvic Pain, Functional Abdominal Pain Syndrome, Low Back Pain
- Trial name
- NCT04069572
- Testing
- Vibrotactile Stimulation
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Stanford University
Migraine Disorders
Botox Injection in Treatment of Chronic Migraine
Chronic migraine is in many cases a most disabling condition. Chronic migraine is defined as headaches for at least 15 days per month, of which 8 days have typical migraine features.
- Trial name
- NCT02259075
- Testing
- Botulinum Toxin Type A
- Where
- Norway
- Volunteers
- 10 people
- Sponsor
- Norwegian University of Science and Technology
Migraine Disorders
A Multicenter Assessment of ALD403 in Chronic Migraine
The purpose of this study is to assess ALD403 in the prevention of migraine headache in chronic migraineurs.
- Trial name
- NCT02275117
- Testing
- ALD403
- Where
- 92 sites in United States, Australia and 2 more
- Volunteers
- 665 people
- Sponsor
- Alder Biopharmaceuticals, Inc.
Migraine Disorders, Facial Pain Disorder, Cluster Headache, Trigeminal Neuralgia, Trigeminal Autonomic Cephalalgias
Sphenopalatine Ganglion Pulsed Radiofrequency Treatment Outcomes
Purpose of the Study: This study aims to evaluate the clinical effectiveness and long-term outcomes of "Sphenopalatine Ganglion (SPG) Pulsed Radiofrequency (PRF)" treatment in patients with chronic headaches and facial pain.
- Trial name
- SPG-PRF (NCT07370142)
- Testing
- Pulsed Radiofrequency of the Sphenopalatine Ganglion
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people
- Sponsor
- Ankara City Hospital Bilkent
Chronic Migraine, Headache, Chronic Migraine
Rate , Predictors and Outcome of Chronic Migraine
Nowadays, headache has been considered as one of the top global disabling medical conditions.1 Migraine is an important type of headache, and one of the chronic multifaceted neuro-inflammatory disorders.2 It is characterized by…
- Trial name
- NCT05079659
- Where
- Egypt
- Volunteers
- 296 people, healthy volunteers welcome
- Sponsor
- Assiut University
Chronic Daily Headache
Nutrition for Chronic Daily Headache
The purpose of this study is: 1) To assess the feasibility of implementing a clinical trial comparing two potentially analgesic dietary interventions in patients with chronic daily headache (CDH) and 2)To assess the preliminary…
- Trial name
- NCT01157208
- Testing
- Diet A, Diet B
- Where
- United States
- Volunteers
- 67 people
- Sponsor
- University of North Carolina, Chapel Hill
Cervicogenic Headache
Effects of SNAGS Along With Thoracic Postural Correction Techniques in Patients With Chronic Cervicogenic Headache
The aim of this study is to find out the effects of Mulligan SNAGs along with thoracic postural correction techniques on patients with chronic cervicogenic headache.
- Trial name
- NCT04993950
- Testing
- sustained natural apophyseal glides, SNAGS with thoracic postural correction techniques
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Myofascial Trigger Points, Chronic Musculoskeletal Pain
Clinical Study of Myofascial Trigger Points(MTrPs) Injection in the Treatment of Shoulder Osteoarthritis(OA)
Chronic musculoskeletal pain (CMP) is a common disease in China, with a high incidence among the elderly, and has a significant impact on patients' quality of life. Shoulder osteoarthritis is a common type of CMP.
- Conditions
- Myofascial Trigger Points, Chronic Musculoskeletal Pain, Shoulder Osteoarthritis
- Trial name
- NCT07347054
- Testing
- Joint Cavity Injection, MTrPs Injection
- Where
- China
- Volunteers
- 1,036 people
- Sponsor
- Beijing Tiantan Hospital
Chronic Migraine, Headache
Adjunctive Treatment of Chronic Migraine Using an Oral Dental Device
Single blinding study comparing FDA cleared device for prevention of medically diagnosed migraine pain to placebo.
- Trial name
- NCT04871581
- Testing
- NTI-tss
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- ChairsideSplint.com
Rheumatoid Arthritis, Ankylosing Spondylitis
PatientSpot Formerly Known as ArthritisPower
Patient Power is a patient research network and database (registry) to collect prospective information about demographics, self-reported diagnoses and medications, and willingness to participate in research from participants with…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Fibromyalgia, Gout
- Trial name
- NCT03840928
- Where
- United States
- Volunteers
- 40,000 people, healthy volunteers welcome
- Sponsor
- Global Healthy Living Foundation
Tension-Type Headache, Chronic Tension-type Headache
Efficacy of a Multimodal Physiotherapy Program and Mobile-App Guided Meditation in Adults With Frequent or Chronic Tension-Type Headache
The goal of this clinical trial is to evaluate whether a multimodal physiotherapy program and guided meditation using a mobile app can help reduce headache pain and improve quality of life in adults with frequent or chronic…
- Conditions
- Tension-Type Headache, Chronic Tension-type Headache, Frequent Episodic Tension-Type Headache
- Trial name
- JBE-CEF (NCT07240532)
- Testing
- Multimodal Physiotherapy for Tension-Type Headache, Guided Meditation Using Insight Timer App
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Universidad de Granada
Headache Disorders, Secondary, Post-Dural Puncture Headache
Association Between Chronic Headache and Back Pain With Childbirth
This study uses a single questionnaire to evaluate two separate primary outcomes: 1. To identify association between chronic headache in women who have given birth to children as compared to a control group of women who have…
- Conditions
- Headache Disorders, Secondary, Post-Dural Puncture Headache, Migraine Disorders, Back Pain
- Trial name
- NCT04091321
- Where
- United States
- Volunteers
- 1,112 people
- Sponsor
- Stanford University
Tension-Type Headache
Gonyautoxin in the Treatment of Chronic Tension-Type Headache
The purpose of this study is to evaluate the clinical efficacy of Gonyautoxin 2/3 epimers in the treatment of patients diagnosed with chronic tensional-type headache in accordance with International Headache Society guidelines
- Trial name
- NCT00276952
- Testing
- Gonyautoxin
- Where
- Chile
- Volunteers
- 27 people
- Sponsor
- University of Chile
Headache, Physical Activity
Exercise Training With Physically Active Lifestyle to Reduce Headache and Quality of Life
The aim of this intervention study is to examine whether tailored exercise therapy training is effective and cost-effective to decrease headache frequency and intensity, reduce medication used for chronic headache and patients´…
- Conditions
- Headache, Physical Activity, Quality of Life
- Trial name
- HEADEX (NCT01664585)
- Testing
- Training group, Control
- Where
- 3 sites in Finland
- Volunteers
- 116 people
- Sponsor
- UKK Institute
Headache, Jugular Vein Occlusion
Safety Profile of PETALO CVS in the Treatment of Non-thrombotic Internal Jugular Vein Stenosis and Chronic Headache
The purpose of the study is to assess, as first stage, the safety profile of an innovative venous- oriented device (Petalo CVS) in the treatment of patients with non-thrombotic internal jugular vein stenosis and chronic headache…
- Trial name
- PETALO (NCT04352218)
- Testing
- PTA + Stenting using "Petalo stent", Percutaneous Transluminal Angioplasty (PTA)
- Volunteers
- 60 people
- Sponsor
- University of Catania
Cluster Headache - Episodic and Chronic
Safety and Efficacy Study of SOM230 s.c. in Cluster Headache
The purpose of this study was to determine if SOM230 is safe and effective for the treament of cluster headache.
- Trial name
- NCT02619617
- Testing
- SOM230
- Where
- 4 sites in United States, Germany and 1 more
- Volunteers
- 28 people
- Sponsor
- Novartis Pharmaceuticals
Chronic Daily Headache
Effect of Intranasal Oxytocin on Headache in Chronic Daily Headache
The objective of this prospective, randomized, double-blind, parallel-group, placebo-controlled study is to determine the effectiveness of intranasal oxytocin in subjects suffering from chronic daily headache.
- Trial name
- NCT00963040
- Testing
- Syntocinon, Sterile water
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- MedVadis Research Corporation
New Daily Persistent Headache (NDPH)
Endogenous Modulation and Central Sensitization in New Daily Persistent Headache ( NDPH ) in Children
New daily persistent headache (NDPH) is a primary headache disorder characterized by the daily and unremitting headache pain patients experience with a distinct onset.
- Trial name
- EMCS-NDPH (NCT03447782)
- Testing
- Naltrexone HCl (Bulk) Powder
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Cluster Headache
Botulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic Cluster Headache
Cluster headache is a primary headache condition characterized by clusters of one-sided, high-intensity pain attacks. The headache may be episodic or chronic. Treatment options are limited and their effects unsatisfactory.
- Trial name
- BASIC (NCT03944876)
- Testing
- Botulinum toxin type A
- Where
- 5 sites in Germany, Italy and 3 more
- Volunteers
- 112 people
- Sponsor
- Norwegian University of Science and Technology