Clinical trials: Chronic Functional Constipation
Abdominal Pain, Constipation - Functional
Lactobacillus Reuteri in Treatment of Functional Abdominal Pain and Chronic Constipation in Children
Beneficial therapeutic effect of probiotics has been reported in children with irritable bowel syndrome, but not consistently in other functional gastrointestinal disorders.
- Trial name
- NCT01587846
- Testing
- Administration of L.reuteri in children with abdominal pain, Administration of L.reuteri in children with constipation
- Where
- Croatia
- Volunteers
- 300 people
- Sponsor
- Sisters of Mercy University Hospital
Irritable Bowel Syndrome
Prevalence of Intestinal Parasitic Infections in Patients With Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is common medical disorder and represent a group of diseases of the gastrointestinal tract that is characterized by chronic abdominal pain , bloating , passage of mucus or straining with bowel…
- Trial name
- NCT05830370
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sohag University
Constipation
Functional Magnetic Stimulation Enhances Gastrointestinal Motility in Patients With Chronic Constipation
The purpose of this study is to evaluate the effects of Functional Magnetic stimulation (FMS) on gastrointestinal motility in patients suffering from chronic constipation due to non-neurological issues.
- Trial name
- NCT01786837
- Testing
- Functional Magnetic Stimulation
- Where
- United States
- Sponsor
- The Cleveland Clinic
Chronic Constipation, Functional Constipation
A Phase 2 Study to Evaluate Pharmacodynamics of YKP10811 in Patients With Chronic or Functional Constipation
This will be a single-center, randomized, parallel group, multiple dose administration, double-blind, placebo-controlled study to evaluate the effects of YKP10811 on gastric, small bowel, and colonic transit in patients with…
- Trial name
- NCT01523184
- Testing
- YKP10811 Drug Product Capsule
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- SK Life Science, Inc.
Constipation
The Effects of Abdominal Massage on Functional (Primary) Chronic Constipation
The aim of the present study is to investigate the efficacy of abdominal massage in patients with functional (primary) chronic constipation. The present study is designed as a randomized placebo controlled.
- Trial name
- NCT03764995
- Testing
- Standard bowel management, Abdominal massage
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Hacettepe University
Constipation
Effectiveness of Electromagnetic Field Therapy in Chronic Constipation
This study was, randomise controlled study. The aim of this study was to determine the effect of transabdominal magnetic field therapy on constipation severity in patients with chronic functional constipation.
- Trial name
- NCT06578442
- Testing
- Magnetic Field Treatment, Standard Care Group
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Medipol University
Chronic Constipation
Physiotherapeutic Intervention in Children With Chronic Functional Constipation
The purpose of this study is to determine whether physiotherapy is effective in the treatment of the chronic functional constipation in children.
- Trial name
- NCT00906971
- Testing
- diaphragmatic breathing, isometric training of the abdominal muscles and abdominal massage
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- Universidade Federal de Pernambuco
Bladder Dysfunction, Bowel Dysfunction
Comparison of Transcutaneous Electrical Nerve Stimulation and Manual Therapy in Children With Cerebral Palsy
There are many studies in the literature on healthy children with lower urinary tract dysfunction (LUTD), but there are limited number of studies in children with cerebral palsy (CP) with LUTD.
- Conditions
- Bladder Dysfunction, Bowel Dysfunction, Cerebral Palsy, Neurogenic Bladder
- Trial name
- NCT05351138
- Testing
- TENS, Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Bahçeşehir University
Constipation
Efficacy and Tolerability of Cassia Fistula Plus Senna Alexandrina Miller (Sugar Free) in the Chronic Functional Constipation (CFC).
Primary Objective: To evaluate the clinical efficacy of Naturetti (jelly sugar free) To test medication on subjects who suffer chronic functional constipation in 30 days use.
- Trial name
- NCT00931853
- Testing
- SENNA+CASSIA(Naturetti)
- Where
- Brazil
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Sanofi
Chronic Functional Constipation
The Efficacy of Long-Course Treatment Using Vibrating Capsules for Chronic Constipation
This is a single-center trial. It enrolled nine 18- to 85-year-old patients with chronic constipation to evaluate the efficacy of long-course treatment by using vibrating capsule (VC).
- Trial name
- NCT06553664
- Testing
- Treat with Vibrabot capsules for at least 7 weeks
- Where
- China
- Volunteers
- 9 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Constipation
A Study to Evaluate the Effects of a Natural Supplement in Adults With Chronic Functional Constipation
Constipation is common in the general population, especially in women and in the elderly. Hard stool is a complaint often associated with constipation, which suggests that stool softening would provide a major benefit in the…
- Trial name
- NCT02073006
- Testing
- Natural Fibre Supplement
- Where
- Ireland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Atlantia Food Clinical Trials
Constipation, Constipation by Outlet Obstruction
The Impact of Aerobic Interval and Inspiratory Muscle Training On Patient Reported Outcome Scores In Individuals With Chronic Constipation
The primary aim of this study will be to determine if the addition of aerobic interval and inspiratory muscle training (IMT) targeted at improving cardiopulmonary-based measures will further improve patient satisfaction scores in…
- Conditions
- Constipation, Constipation by Outlet Obstruction, Constipation-predominant Irritable Bowel Syndrome, Constipation - Functional
- Trial name
- NCT05321953
- Testing
- Standard Physical Therapy Care, Aerobic and Inspiratory Muscle Training
- Where
- United States
- Sponsor
- University of Miami
Constipation
Investigation of the Additional Effects of Aerobic Exercise Training to Abdominal Massage in Functional Constipation
The aim of this study was to investigate the additional effects of aerobic exercise to abdominal massage in patients with functional constipation.
- Trial name
- NCT06298331
- Testing
- Aerobic Exercise, Abdominal Massage, Patient Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Hacettepe University
Chronic Idiopathic Constipation
SP-304 Dose Ranging Study in Patients With Chronic Idiopathic Constipation
This is a Phase 2a, randomized, double-blind, placebo-controlled, 14-day repeat oral, dose ranging study to determine the safety, pharmacokinetics (PK) and pharmacodynamics (PD) effects of SP-304 in patients with chronic…
- Trial name
- CIC (NCT01053962)
- Testing
- SP-304 0.3 mg, SP-304 1.0 mg, SP-304 3.0 mg
- Where
- 14 sites in United States
- Volunteers
- 84 people
- Sponsor
- Bausch Health Americas, Inc.
Constipation - Functional
Transcutaneous Electrical Acupoint Stimulation (TEAS) for Chronic Constipation
Transcutaneous electrical acupoint stimulation (TEAS) is an emerging technology for non-invasive neuromodulation that has broad potential implications and warrants further study.
- Trial name
- NCT03243955
- Testing
- Verum TEAS
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Chronic Constipation
Evaluate the Safety and Efficacy of a 5-HT4 Agonist in Chronic Constipation (ACCORD Trial)
Study 0038 compares the safety and effectiveness of an investigational drug, TD-5108 with placebo (a sugar pill) for the treatment of chronic constipation.
- Trial name
- NCT00391820
- Testing
- TD-5108
- Where
- United States
- Volunteers
- 360 people
- Sponsor
- Alfasigma S.p.A.
Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C)
"Efficacy and Safety of Linaclotide in Chronic Constipation"
Goal of this study is to evaluate the efficacy and safety of two different doses of Linaclotide in improving bowel function and patient-reported outcomes among Bangladeshi patients with chronic constipation for 8 weeks along with…
- Conditions
- Chronic Idiopathic Constipation, Irritable Bowel Syndrome (IBS-C), Chronic Constipation, CIC
- Trial name
- LIN-CC-BD (NCT07431957)
- Testing
- Linaclotide 72 micrograms, Linaclotide 145 micrograms
- Where
- Bangladesh
- Volunteers
- 90 people
- Sponsor
- Md Mehedi Shahriar
Chronic Functional Constipation
Comparative Study of Different Dosages of Vibrabot Capsule in the Treatment of Chronic Functional Constipation
This is a single-center trial that enrolls 120 18- to 85-year-old patients with mild to moderate chronic functional constipation to study the dose-response relationship of the Vibrabot capsule as well as the mechanism of action…
- Trial name
- NCT06526767
- Testing
- Vibrabot capsules twice a week, Vibrabot capsules three times a week, Vibrabot capsules five times a week
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Tsinghua Chang Gung Hospital
Defecation Disorder, Constipation - Functional
Barriers to Rectal Irrigation in Defaecatory Dysfunction
Rectal irrigation is the introduction of warm tap water through the anal canal into the rectum to initiate defaecation. NICE recommends that rectal irrigation be considered in patients with constipation(1) and faecal incontinence…
- Conditions
- Defecation Disorder, Constipation - Functional, Constipation by Outlet Obstruction, Faecal Incontinence
- Trial name
- NCT06569446
- Testing
- There is no intervention. This a qualitative study to explore barriers to rectal irrigation
- Volunteers
- 34 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Constipation
Evaluation of Cassia Fistula + Senna Alexandrina Miller in the Chronic Functional Constipation Treatment.
Primary Objective: To evaluate the clinical efficacy of Naturetti (capsules) , considering the following criteria: Evacuation frequency during the treatment and follow-up period Consistency of stools during the treatment and…
- Trial name
- NCT00994851
- Testing
- SENNA+CASSIA
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- Sanofi