Clinical trials: Chronic Fatigue Syndrome (CFS)
Chronic Fatigue Syndrome (CFS)
Controlled Trial of Hydrogen Water as a Treatment for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
This is a 16-week controlled treatment trial of an over-the -counter supplement, hydrogen water, for individuals with ME/CFS patients. An active treatment condition will be compared to a placebo-control condition.
- Trial name
- ME/CFS (NCT07753122)
- Testing
- Molecular hydrogen produced by a metallic magnesium tablet, consumed 3x a day dissolved in water. Treatment duration is 16 weeks.
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Fred Friedberg
Fatigue Syndrome, Chronic, Epstein-Barr Virus Infection
Mental Training for CFS Following EBV Infection in Adolescents
The general aim of this study is to investigate the effect of an individually tailored mental training program in adolescents developing chronic fatigue syndrome (CFS) after an acute Epstein Barr-virus (EBV) infection.
- Trial name
- NCT02499302
- Testing
- Mental training
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Long COVID, Postural Orthostatic Tachycardia Syndrome
The Long COVID-19 Wearable Device Study
To further characterize Long COVID-19 by collecting data from individuals who already own wearable devices or are provided with a wearable device along with basic and enhanced educational materials to determine if both can…
- Conditions
- Long COVID, Postural Orthostatic Tachycardia Syndrome, Dysautonomia, Myalgic Encephalomyelitis
- Trial name
- NCT05741112
- Testing
- Wearable device
- Where
- United States
- Volunteers
- 100,500 people
- Sponsor
- Scripps Translational Science Institute
Chronic Fatigue Syndrome
Cytokine Inhibition in Chronic Fatigue Syndrome Patients
Rationale: Chronic fatigue syndrome (CFS) is a medically unexplained syndrome for which no somatic or pharmacological treatment has been proven effective.
- Trial name
- CiCFS (NCT02108210)
- Testing
- Anakinra
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Chronic Fatigue Syndrome
Discovering Trends in Chronic Fatigue Syndrome Patients' Clinical Study Experiences
The study seeks to delve into the firsthand experiences of patients diagnosed with chronic fatigue syndrome who partake in a separate clinical trial featuring a specific medical intervention.
- Trial name
- NCT05967494
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Bodily Distress Syndrome, Functional Somatic Disorder
DISTRESS Trial Functional Disorders - the DISTRESS Trial
A Diagnostic Clinic for Functional Somatic Disorders (FSD) has been set up at the outpatient diagnostic center at Regionshospitalet Silkeborg.
- Trial name
- DISTRESS (NCT06025617)
- Testing
- Diagnostic evaluation at the Diagnostic Clinic for Functional Disorders, Diagnostic as usual
- Where
- Denmark
- Volunteers
- 290 people
- Sponsor
- Regionshospitalet Silkeborg
Chronic Fatigue Syndrome (CFS), Myalgic Encephalomyelitis (ME)
Cyclophosphamide in Myalgic Encephalopathy/ Chronic Fatigue Syndrome (ME/CFS)
Significant clinical improvements of ME/CFS symptoms were observed in two patients with long-standing ME/CFS who received adjuvant chemotherapy including cyclophosphamide for breast cancer, also in one ME/CFS patient who received…
- Trial name
- CycloME (NCT02444091)
- Testing
- Cyclophosphamide
- Where
- Norway
- Volunteers
- 40 people
- Sponsor
- Haukeland University Hospital
Chronic Fatigue Syndrome/ Myalgic Encephalitis (CFS/ME), Post COVID Syndrome
Effectiveness and Safety of a Tele-Rehabilitation Program on Fatigue and Related Variables in Chronic Fatigue Syndrome and Post COVID Syndrome
This is a randomized, single-blind clinical trial that aims to evaluate the effectiveness of a tele-rehabilitation program based on mindful and conscious movement-based exercise (including adapted yoga, breathing exercises, and…
- Trial name
- NCT06978582
- Testing
- Mindful and conscious movement-based exercise, Conventional exercise
- Where
- Spain
- Volunteers
- 147 people
- Sponsor
- University of Seville
Chronic Fatigue Syndrome (CFS), Quality of Life
Photobiomodulation in Chronic Fatigue Syndrome
The goal of this clinical trial is to evaluate whether photobiomodulation therapy (low-level laser therapy) can reduce fatigue and improve quality of life in patients with chronic fatigue syndrome (CFS).
- Trial name
- NCT07546539
- Testing
- Photobiomodulation (Low-Level Laser Therapy)
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- University of Lahore
Myalgic Encephalomyelitis, Chronic Fatigue Syndrome
A Non-Interventional Pilot Study to Explore the Role of Gut Flora in ME/CFS
This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records regarding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).
- Trial name
- NCT04100915
- Testing
- No Intervention
- Where
- United States
- Sponsor
- ProgenaBiome
Fatigue Syndrome, Chronic, Cardiovascular Diseases
Is Post-exertional Symptom Exacerbation Specific to Patients With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome? A Study Comparing Patients With Myalgic Encephalomyelitis / Chronic Fatigue Syndrome and Patients With Cardiac Diseases Who Underwent an Exercise Test.
Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME/CFS) is a disease characterized by persistent and unexplained fatigue associated with diffuse pain, sleep disorders, neurocognitive and autonomic symptoms, musculoskeletal…
- Trial name
- MAPEMCAR (NCT07491315)
- Testing
- Exercise test on ergocycle, Near Infrared Spectroscopy (NIRS)
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hôpital Européen Marseille
ME/CFS, Long COVID
Is Swimming a More Tolerable Form of Movement for Individuals With Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome?
Individuals with ME/CFS experience profound exercise intolerance and post-exertional malaise. This remote (app-based) pilot study explores whether light, fully self-paced, swimming may be a tolerable form of movement for people…
- Conditions
- ME/CFS, Long COVID, Post- COVID-19 Syndrome, POTS - Postural Orthostatic Tachycardia Syndrome
- Trial name
- ME/CFS (NCT07454395)
- Testing
- Swimming, Cycling
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Simon Fraser University
Fibromyalgia (FM), Chronic Fatigue Syndrome (CFS)
Molecular Response to Custom Manual Physiotherapy Treatment of Fibromyalgia & Chronic Fatigue Syndrome (CFS)
Fibromyalgia (FM)and Chronic Fatigue Syndrome (CFS) are complex diseases often presenting overlapping symptomatology. Manual therapy (MT) protocols report benefits for pain treatment of FM, but the underlying mechanisms for…
- Trial name
- NCT04174300
- Testing
- Manual Therapy
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Chronic Fatigue Syndrome
Use of Sildenafil (Viagra) to Alter Fatigue, Functional Status and Impaired Cerebral Blood Flow in Patients With CFS
Use of Viagra to Alter Symptoms in Patients with Chronic Fatigue Syndrome (CFS)
- Trial name
- NCT00598585
- Testing
- Sildenafil (Viagra)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Charles Drew University of Medicine and Science
Irritable Bowel, Fibromyalgia
Psychiatric Disorders and Functional Somatic Disorders
The objectives of this study are: Firstly, to investigate the association between psychiatric disorders and functional somatic disorder (FSD).
- Conditions
- Irritable Bowel, Fibromyalgia, Chronic Fatigue Syndrome, Bodily Distress Syndrome
- Trial name
- NCT06006715
- Volunteers
- 7,493 people, healthy volunteers welcome
- Sponsor
- Aarhus University Hospital
Fibromyalgia, Irritable Bowel Syndrome
A Computer-Based Intervention for Medically Unexplained Physical Symptoms
In this study 60 people with medically unexplained physical symptoms (MUPS) will receive either a 6-session resilience skill building intervention provided fully online or a weekly computerized journaling assignment.
- Conditions
- Fibromyalgia, Irritable Bowel Syndrome, Chronic Fatigue Syndrome
- Trial name
- NCT00468013
- Testing
- Resilience Building Exercises, Journaling
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Medicine and Dentistry of New Jersey
Chronic Fatigue With OSA, Chronic Fatigue Syndrome With OSA
Nasal Continuous Positive Airway Pressure (CPAP) in Chronic Fatigue and Sleep-disordered Breathing
Chronic fatigue (CF) and chronic fatigue syndrome (CFS) are disabling disorders that may be induced or aggravated by underlying sleep disturbances. The relationship between sleep quality and fatigue is still not fully elucidated.
- Trial name
- NCT01368718
- Where
- Belgium
- Volunteers
- 5 people
- Sponsor
- University Hospital, Ghent
Chronic Pain, Fibromyalgia
Developing an Activity Pacing Framework: Feasibility and Acceptability
This study explores whether it is feasible to use a newly developed activity pacing framework to standardise how activity pacing is instructed by healthcare professionals in rehabilitation programmes for patients with chronic…
- Conditions
- Chronic Pain, Fibromyalgia, Chronic Fatigue Syndrome, Chronic Low Back Pain
- Trial name
- NCT03497585
- Testing
- Activity pacing framework
- Where
- United Kingdom
- Volunteers
- 112 people
- Sponsor
- Pennine Acute Hospitals NHS Trust
Chronic Fatigue Syndrome, Intensive Care Unit
Chronic Fatigue Etiology and Recovery in Covid-19 Patients: the Role of Fatigability
Chronic fatigue is the most common and debilitating symptom in intensive care unit (ICU) survivors. Indeed, it has been widely reported that patients who stayed in ICU for prolonged periods report a feeling of tiredness for…
- Conditions
- Chronic Fatigue Syndrome, Intensive Care Unit, Muscle
- Trial name
- FatCovid-19 (NCT04363606)
- Testing
- Questionnaires, blood test, Maximal effort test
- Where
- 8 sites in France
- Volunteers
- 69 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Chronic Fatigue Syndrome
Exertional Exhaustion in Chronic Fatigue Syndrome
Post-exertional malaise was modeled by having Chronic Fatigue Syndrome (CFS) and sedentary control subjects perform submaximal exercise on 2 consecutive days with objective changes in brain function measured by magnetic resonance…
- Trial name
- NCT03567811
- Testing
- Submaximal bicycle exercise stress test on Days 1 and 2
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Georgetown University