Clinical trials: Chorionic Villus Sampling
Hereditary Diseases
Cell-based Non-invasive Prenatal Testing as an Alternative to Invasive Chorionic Villus Sampling
The study aims to evaluate cell-based non-invasive prenatal testing (cbNIPT) as an alternative to invasive chorionic villus sampling (CVS) in patients who achieve pregnancy following preimplantation genetic testing for hereditary…
- Trial name
- NCT05453474
- Testing
- Whole genome amplification
- Where
- Denmark
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Aalborg University Hospital
Chorionic Villi Sampling
Pain Perception During Chorionic Villus Sampling
Chorionic villous sampling is a frequent procedure used for antenatal genetic testing. This procedure is associated with anxiety and fear of pain that can be expected during the procedure, often prejudicing patients against this…
- Trial name
- NCT03140293
- Testing
- Lidocaine injection, Gebauer Ethyl Chloride Spray
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Angela Bianco
Maternal Anxiety, Prenatal Diagnosis
Effect of Video -Based vs Standard ınformation on Maternal Anxiety and Procedure Decision in Pregnant Woman Offered Amniocentesis or Cvs
This prospective study evaluates the impact of video-based patient education compared to standard verbal informed consent on state anxiety levels and procedure acceptance rates in pregnant women undergoing invasive prenatal…
- Conditions
- Maternal Anxiety, Prenatal Diagnosis, Amniocentesis, Chorionic Villus Sampling
- Trial name
- NCT07876726
- Testing
- Multilingual Video-Based Patient Education, Standard Verbal Informed Consent
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ankara City Hospital Bilkent
Pain
MEOPA Versus Local Anesthesia for Analgesia During Chorionic Villus Sampling.
determine if efficiency of MEOPA anesthesia is at least equivalent to local anesthetics into the chorionic villus sampling in the first trimester of pregnancy
- Trial name
- MELIBIO (NCT02573987)
- Testing
- Oxygen/nitrous oxide equimolar mix, Lidocaine
- Where
- France
- Volunteers
- 192 people
- Sponsor
- Hospital St. Joseph, Marseille, France
Prenatal Diagnoses, Preimplantation Genetic Diagnosis
Cell Based Non Invasive Prenatal Testing as an Alternative to Chorionic Villus Sampling Following Preimplantation Genetic Testing
The study aims to investigate whether cell-based non-invasive prenatal testing (cbNIPT) can be used as an alternative to invasive chorionic villus sampling (CVS) in patients who achieve pregnancy following preimplantation genetic…
- Trial name
- NCT04584047
- Testing
- Cell-based non-invasive prenatal testing
- Where
- Denmark
- Volunteers
- 8 people
- Sponsor
- Aalborg University Hospital
Pregnancy, Down Syndrome
An Interactive Informed Consent and Education Program for Pregnant Women
The purpose of this study is to determine whether an interactive education program for prenatal testing is effective in improving pregnant women's understanding of and expectations towards prenatal screening and diagnosis.
- Trial name
- NCT01176019
- Testing
- Information about Prenatal Screening and Diagnosis
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Amniocentesis, Chorionic Villus Sampling
Multımedia Information Before Amniocentesıs And Chorion Villus Sampling
It is known that the anxiety levels of pregnant women are high before amniocentesis and chorionic villus sampling and it is often neglected.
- Trial name
- NCT06572436
- Testing
- Multimedia information training
- Volunteers
- 90 people
- Sponsor
- Akdeniz University
Down Syndrome, Edwards Syndrome
Non-Invasive Screening for Fetal Aneuploidy
The purpose of this study is to determine if a laboratory test developed by the Sequenom Center for Molecular Medicine (SCMM) that uses a new marker found in the mother's blood can better identify pregnancies that have a child…
- Trial name
- NCT00847990
- Testing
- Maternal blood screening test for fetal aneuploidy
- Where
- 25 sites in United States
- Volunteers
- 5,000 people
- Sponsor
- Sequenom, Inc.
Pregnancy
Prenatal Testing: Amniocentesis Versus Transabdominal Chorionic Villus Sampling (TA CVS)
Prenatal diagnosis can provide information to parents about specific fetal disorders. However, invasive prenatal diagnostic procedures are associated with risks to the fetus.
- Trial name
- NCT00065897
- Testing
- Amniocentesis, Transabdominal chorionic villus sampling (TA CVS)
- Volunteers
- 6,400 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Down Syndrome, Aneuploidy
Noninvasive Screening for Affected Pregnancies: Assay Development & Optimization in Affected Pregnancies
To collect samples for the purpose of developing and optimizing an in vitro noninvasive prenatal diagnostic (NIPD) test. The NIPD test employs circulating cell free (ccff) DNA extracted from whole blood samples collected from…
- Trial name
- CHARMM-AP (NCT01052688)
- Testing
- Maternal blood draw of 30 to 50ml
- Where
- 10 sites in United States
- Volunteers
- 150 people
- Sponsor
- Sequenom, Inc.
Pregnancy
Invasive Prenatal Testing Decisions in Pregnancy After Infertility
This study will explore the decision-making experiences of women who are currently pregnant following a period of infertility on whether or not to undergo an invasive prenatal test (IPT) procedure, such as amniocentesis or…
- Trial name
- NCT00341822
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- National Human Genome Research Institute (NHGRI)